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Browse our Enkephalin Proteins (PENK)

Full name:
Proenkephalin Proteins (PENK)
On www.antibodies-online.com are 10 Proenkephalin (PENK) Proteins from 6 different suppliers available. Additionally we are shipping Enkephalin Antibodies (118) and Enkephalin Kits (43) and many more products for this protein. A total of 183 Enkephalin products are currently listed.
Synonyms:
2410002E02Rik, AI326464, ecat4, Enk, Penk, Penk-rs, Penk1, Penk2, penkl, PPA, zgc:73353
list all proteins Gene Name GeneID UniProt
PENK 71950 Q80Z64
PENK 29237 P04094
PENK 5179 P01210

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Enkephalin Proteins (PENK) by Origin

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More Proteins for Enkephalin Interaction Partners

Zebrafish Proenkephalin (PENK) interaction partners

Mouse (Murine) Proenkephalin (PENK) interaction partners

  1. NANOG as a key regulator connecting the pluripotency network with constitutive heterochromatin organization in mouse embryonic stem cells.

  2. Data indicate that Nanog homeobox (show NANOG Proteins) protein (show HOXA1 Proteins) is important for the effects of reprogramming media.

  3. Nanog (show NANOG Proteins) enhances proliferation of fibroblasts through transcriptional regulation of cell cycle inhibitor p27 (show CDKN1B Proteins) gene.

  4. The different embryonic stem cells Nanog (show NANOG Proteins)-expressing populations differ in their differentiation propensities. Nanog (show NANOG Proteins) upregulation is not well correlated to Oct4 (show POU5F1 Proteins), Sox2 (show SOX2 Proteins) and Klf4 (show KLF4 Proteins) expression, or cell cycle phase.

  5. 1After the 32-cell stage, when embryos form the blastocyst cavity, Nanog expression was upregulated mainly in ICM cells while it was repressed in the future primitive endoderm lineage in an FGF signaling-dependent manner in the later stages

  6. Nanog is able to transform normal somatic cells into tumor cells.

  7. NANOG represses mitochondrial oxidative phosphorylation genes, as well as reactive oxygen species generation, and activates fatty acid oxidation to support tumor initiating cell self-renewal and drug resistance.

  8. The cellular reprogramming-promoting function of mitoflashes occurs via the upregulation of Nanog expression.

  9. the existence of three stable steady states for Nanog levels, which are the same in all the different conditions of the cell-culture medium.

  10. NANOG (show NANOG Proteins) binds to GLI1 (show GLI1 Proteins) and GLI3 (show GLI3 Proteins) proteins and represses Hedgehog (show SHH Proteins)-mediated transcription.

Pig (Porcine) Proenkephalin (PENK) interaction partners

  1. The expression of the genes coding for proopiomelanocortin (POMC (show POMC Proteins)), proenkephalin (PENK) and prodynorphin (PDYN (show PDYN Proteins)) in porcine luteal cells isolated from corpora lutea (CL) collected on days 3-6, 8-10 and 13-16 of the oestrous cycle is reported.

Human Proenkephalin (PENK) interaction partners

  1. Nav1.7 (show SCN9A Proteins) deletion has profound effects on gene expression, leading to an upregulation of enkephalin precursor Penk mRNA and met-enkephalin protein in sensory neurons.

  2. The PENK polymorphism-and potentially opioid neurotransmission more generally-modulates functioning and structural integrity of brain regions.

  3. Serum PENK-A levels were not associated with all-cause mortality in patients with type 2 diabetes mellitus, and its association with cardiovascular mortality was strongly attenuated after accounting for all traditional risk factors.

  4. BSP (show KLK6 Proteins) demonstrated that emodin, to a certain degree, affected the demethylation of tumor-suppressor genes P16, RASSF1A (show RASSF1 Proteins), and ppENK in the pancreatic cancer cell line PANC-1.

  5. increased plasma PENK-A levels are associated with disease severity and in-hospital mortality after acute intracerebral hemorrhage.

  6. enhanced plasma proenkephalin A could be a useful, complementary tool to predict short- or long-term clinical outcome after severe traumatic brain injury.

  7. EPS led to the discovery of two novel immunomodulatory proteins, MFAP5 (show MFAP5 Proteins) and PENK that when administered to mice subjected to endotoxemic shock, reversed the cytokine storm and provided a significant survival benefit

  8. Data from women undergoing hysterectomy for uterine fibroids suggest that uterine isthmian-cervical region exhibits nerve fibers expressing enkephalin (ENK); uterine fundus/corpus myoma pseudocapsules do not exhibit nerve fibers expressing ENK.

  9. Promoter methylation of WIF1 (show WIF1 Proteins), PENK and NPY (show NPY Proteins) is associated with colorectal adenocarcinoma (CRC (show CALR Proteins)) diagnosis and can be used to CRC (show CALR Proteins) from other cancers.

  10. Expression of preproenkephalin is significantly decreased in brain from HIV-1 infected patients compared to HIV-1 negative subjects.

Enkephalin (PENK) Protein Profile

Protein Summary

Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT-3'. When overexpressed, promotes cells to enter into S phase and proliferation (By similarity).

Alternative names and synonyms associated with Enkephalin (PENK)

  • proenkephalin (PENK)
  • Proenkephalin A (penk)
  • proenkephalin b (penkb)
  • proenkephalin (penk)
  • proenkephalin a (penka)
  • Nanog homeobox (Nanog)
  • preproenkephalin (Penk)
  • preproenkephalin, related sequence (Penk-rs)
  • proenkephalin (Penk)
  • 2410002E02Rik protein
  • AI326464 protein
  • ecat4 protein
  • Enk protein
  • Penk protein
  • Penk-rs protein
  • Penk1 protein
  • Penk2 protein
  • penkl protein
  • PPA protein
  • zgc:73353 protein

Protein level used designations for Proenkephalin Proteins (PENK)

proenkephalin , Proenkephalin A , PENKa , PENKb , proenkephalin-A , enkephalin a , ES cell-associated protein 4 , early embryo specific expression NK family , early embryo specific expression NK-type homeobox protein , homeobox protein NANOG , homeobox transcription factor Nanog , preproenkephalin 1 , spermatogenic-specific proenkephalin , enkephalin , preproenkephalin 2 , proenkephalin 1 , proenkephalin 2 , proenkephalin related sequence , enkephalin A , preproenkephalin

GENE ID SPECIES
421131 Gallus gallus
477889 Canis lupus familiaris
100196814 Salmo salar
100294557 Ovis aries
464186 Pan troglodytes
360136 Danio rerio
495184 Xenopus laevis
368228 Danio rerio
548461 Xenopus (Silurana) tropicalis
71950 Mus musculus
18619 Mus musculus
100379621 Cavia porcellus
101098113 Felis catus
100152093 Sus scrofa
29237 Rattus norvegicus
768277 Felis catus
5179 Homo sapiens
281387 Bos taurus
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