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Browse our Stromal Antigen 2 Proteins (STAG2)

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Stromal Antigen 2 Proteins (STAG2)
On are 3 Stromal Antigen 2 (STAG2) Proteins from 2 different suppliers available. Additionally we are shipping Stromal Antigen 2 Antibodies (87) and many more products for this protein. A total of 94 Stromal Antigen 2 products are currently listed.
9230105L23Rik, B230112I07Rik, bA517O1.1, RGD1562042, SA-2, sa2, sa2-a, SAP2, SCC3B, stag2, XSA2
list all proteins Gene Name GeneID UniProt
STAG2 10735 Q8N3U4
STAG2 20843 O35638
Rat STAG2 STAG2 313304  

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Stromal Antigen 2 Proteins (STAG2) by Origin

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More Proteins for Stromal Antigen 2 Interaction Partners

Human Stromal Antigen 2 (STAG2) interaction partners

  1. the clinical features of these three cases are remarkably similar to those observed in other well-established cohesinopathies. Herein, we suggest that STAG2 is a dosage-sensitive gene and that heterozygous loss-of-function variants lead to a cohesinopathy.

  2. results indicated that the complete loss of STAG2 expression was predictive for better recurrence-free survival and cancer-specific survival, suggesting its potential value as a prognostic biomarker in bladder cancer

  3. We suggest that increased STAG2 gene copy number and dysregulation of its downstream target genes may be responsible for the specific clinical findings of this syndrome.

  4. Characterization of C-terminal nuclear localization signal of the human SA2 stromalin

  5. Data show a significantly higher stromal antigen 2 (STAG2) mRNA and protein levels in normal bladder cells than bladder cancer cells.

  6. Microduplication of chromosome Xq25 encompassing STAG2 gene in a boy with intellectual disability

  7. STAG2 promotes the correction of kMT (show CAMKMT Proteins) attachment errors to ensure faithful chromosome segregation during mitosis.

  8. Genomic landscape of Ewing sarcoma defines an aggressive subtype with co-association of STAG2 and TP53 (show TP53 Proteins) mutations

  9. Loss of STAG2 expression occurs in 15% of tumors and is associated with metastatic disease, suggesting a potential genetic vulnerability in Ewing sarcoma

  10. our study identifies the duplication of XIAP (show XIAP Proteins) and STAG2 as the minimal duplicated region leading to the ID, facial morphological anomalies, and speech delay, specific to the patients with Xq25 duplication.

Mouse (Murine) Stromal Antigen 2 (STAG2) interaction partners

  1. our data suggests that STAG3 is required for structural changes of chromosomes that mediate chromosome pairing and synapsis, DNA repair and progression of meiosis.

  2. STAG3 is a strong candidate gene for male infertility

  3. STAG3 emerges as the key STAG cohesin involved in major functions of meiotic cohesin.

  4. STAG3-REC8 cohesin complexes have a critical role in supporting meiotic chromosome structure and functions.

  5. E2F6 silences SMC1beta and STAG3 in somatic cells

  6. a cohesin complex containing Rad21 and STAG2 cooperates with a STAG3-specific complex to maintain sister chromatid cohesion during the diplotene stage of meiosis

Stromal Antigen 2 (STAG2) Protein Profile

Protein Summary

Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis- specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I (By similarity).

Alternative names and synonyms associated with Stromal Antigen 2 (STAG2)

  • stromal antigen 2 (STAG2)
  • stromal antigen 2 (stag2)
  • stromal antigen 2 (Stag2)
  • stromal antigen 3 (Stag3)
  • 9230105L23Rik protein
  • B230112I07Rik protein
  • bA517O1.1 protein
  • RGD1562042 protein
  • SA-2 protein
  • sa2 protein
  • sa2-a protein
  • SAP2 protein
  • SCC3B protein
  • stag2 protein
  • XSA2 protein

Protein level used designations for Stromal Antigen 2 Proteins (STAG2)

stromal antigen 2 , stromal antigen 2, isoform 1 , SCC3 homolog 2 , cohesin subunit SA-2 , nuclear protein SA2 , cohesin subunit XSA2 , stromal antigen 2 homolog , xSA-2 , SCC3 homolog 3 , cohesin subunit SA-3 , stromalin 3 , stromalin-3

422360 Gallus gallus
100079984 Ornithorhynchus anatinus
100137587 Papio anubis
100175748 Ciona intestinalis
100301585 Oryzias latipes
100328701 Oryctolagus cuniculus
100470776 Ailuropoda melanoleuca
100565959 Anolis carolinensis
100598212 Nomascus leucogenys
10735 Homo sapiens
492111 Canis lupus familiaris
20843 Mus musculus
313304 Rattus norvegicus
100154944 Sus scrofa
616487 Bos taurus
394319 Xenopus laevis
50878 Mus musculus
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