Browse our Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) ELISA Kits

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Hydroxysteroid (11-Beta) Dehydrogenase 2 ELISA Kits (HSD11B2)
On are 22 Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) ELISA Kits from 6 different suppliers available. Additionally we are shipping Hydroxysteroid (11-Beta) Dehydrogenase 2 Antibodies (98) and Hydroxysteroid (11-Beta) Dehydrogenase 2 Proteins (10) and many more products for this protein. A total of 137 Hydroxysteroid (11-Beta) Dehydrogenase 2 products are currently listed.
11-HSD2, 11HSD2, AME, AME1, HSD2, HSD11B2, HSD11K, MGC81883, SDR9C3
list all ELISA KIts Gene Name GeneID UniProt
HSD11B2 3291 P80365
HSD11B2 15484 P51661
HSD11B2 25117 P50233

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Top referenced Hydroxysteroid (11-Beta) Dehydrogenase 2 ELISA Kits

  1. Human HSD11B2 ELISA Kit for Sandwich ELISA - ABIN420798 : Chang, Suh, Yang, Kang, Lee, Lee, Choi, Lee, Shin, Shin, Kim, Kim, Ahn, Won, Choi, Oh, Kwon, Kim, Park, Lee, Jun, Yu, Lee, Jung, Kwon, Choi, Do, Bae, Kim, Chang, Kim, Lee, Hong: Prenatal maternal distress affects atopic dermatitis in offspring mediated by oxidative stress. in The Journal of allergy and clinical immunology 2016 (PubMed)

More ELISA Kits for Hydroxysteroid (11-Beta) Dehydrogenase 2 Interaction Partners

Human Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) interaction partners

  1. The data demonstrate for the first time that 11b- HSD2 plays a key role in the pathophysiology of malignant epidermal cells.

  2. DNA sequence analysis of affected members of Apparent mineralocorticoid excess family revealed homozygous c.799A>G mutations within exon 4 of HSD11B2, corresponding to a p.T267A mutation of 11betaHSD2.

  3. activation of Hedgehog (show SHH ELISA Kits) signaling is crucial for the upregulation and maintenance of 11beta-HSD2 expression in placenta

  4. Reciprocal regulation of the glucocorticoid metabolizing enzymes, 11beta-hydroxysteroid dehydrogenase types 1 and 2, is associated with steroid-responsiveness and disease remission in childhood nephrotic syndrome.

  5. Rac1 GTPase (show RACGAP1 ELISA Kits) regulates 11beta-HSD2 expression, mineralocorticoid receptor (show NR3C2 ELISA Kits) activation, and mineralocorticoid receptor (show NR3C2 ELISA Kits)-mediated pro-fibrotic signaling.

  6. enhancer of zeste homolog 2 (EZH2 (show EZH2 ELISA Kits)) accounts for the silence of 11beta-HSD2 expression via trimethylation of histone H3 (show HIST3H3 ELISA Kits) lysine 27 at the promoter of the 11beta-HSD2 gene.

  7. Sensitivity to glucocorticoids did not appear to be mediated by changes in the expression of the beta variant of the glucocorticoid receptor or the 11-beta hydroxysteroid dehydrogenase 2 isozyme.

  8. Review of the role of HSD11B2 in pregnancy complications, fetal diseases, and later life morbidity.

  9. Since increased DNA methylation (show HELLS ELISA Kits) in HSD11B2 and FKBP5 (show FKBP5 ELISA Kits) are seen in a minority of bisulfite sequencing clones, these epigenetic changes, and functional consequences, may affect subpopulations of placental cells.

  10. significant positive correlation between DNA methylation of 11beta-HSD2 CpG 1 in infants and maternal sensitivity.

Pig (Porcine) Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) interaction partners

  1. These results indicate that the effects of maternal protein restriction on placental 11beta-HSD2 expression are gender-dependent in the pig, and thyroid hormones may be involved in such effects.

  2. Postnatal ontogeny of 11beta-HSD2 gene expression is described for the first time in stress-related brain regions of domestic pigs at 7, 21, and 35 days of age.

  3. concluded that the 11beta-hydroxysteroid dehydrogenase (11beta-HSD1 (show HSD11B1 ELISA Kits) and 2) system is involved in the regulation of cortisol activity in the testis and thus in the regulation of spermatogenesis

  4. Effects of age, weaning and/or social isolation on the expression of genes regulating HSD11B2.

  5. The expression of 11beta-HSD2 in several types of cells forms consecutive lines of defense may protect spermatogonia against glucocorticoid-induced apoptosis.

  6. 11beta-HSD (show HAL ELISA Kits) type 2, which is abundantly expressed, plays important roles in cortisol inactivation in pig Leydig cells.

  7. The amount of 11beta-HSD 2 in germ cells was greatest at birth, decreased thereafter and was absent after Week 3.

Cow (Bovine) Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) interaction partners

  1. investigation of expression for 11HSD1, 11HSD2, and glucocorticoid receptor (show NR3C1 ELISA Kits) during follicular maturation and atresia: in atretic follicles, expression of 11HSD2 increased in both granulosa cells and theca interna layers

Mouse (Murine) Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) interaction partners

  1. Kidney-specific deficiency of 11beta-HSD2 leads to Salt-dependent Hypertension, which is attributed to mineralocorticoid receptor (show NR3C2 ELISA Kits)-epithelial sodium channel-Na(+)-Cl(-) cotransporter (show SLC12A3 ELISA Kits) activation in the kidney.

  2. Rac1 GTPase (show RACGAP1 ELISA Kits) regulates 11beta-HSD2 expression, mineralocorticoid receptor (show NR3C2 ELISA Kits) activation, and mineralocorticoid receptor (show NR3C2 ELISA Kits)-mediated pro-fibrotic signaling.

  3. Nr3c2 (show NR3C2 ELISA Kits) has a role in mouse skin development in a process that involves HSD11B1 (show HSD11B1 ELISA Kits)/HSD11B2

  4. Reduced brain 11betaHSD2 promotes a hunger for salt and salt sensitivity. 11betaHSD2-positive neurons integrate salt appetite and the blood pressure response to dietary sodium through a mineralocorticoid receptor (show NR3C2 ELISA Kits)-dependent pathway.

  5. 11betaHSD2 inhibition suppressed lung tumor growth and invasion in association with increased tissue active glucocorticoid levels, decreased COX-2 (show COX2 ELISA Kits) expression, inhibition of ERK (show EPHB2 ELISA Kits) and mTOR (show FRAP1 ELISA Kits) signaling pathways.

  6. results show that intestinal epithelial 11ssHSD2 activity contributes to increased COX-2 (show COX2 ELISA Kits) expression in Apc (show APC ELISA Kits)+/min intestinal adenomas and that 11ssHSD2 deficiency in intestinal epithelial cells suppresses adenoma development and growth

  7. 11beta-hydroxysteroid dehydrogenase-2 is a cortisol-inactivating enzyme with a role in keratinocyte cell proliferation and basal cell proliferation

  8. Reduced 11beta-hydroxysteroid dehydrogenase type 2 causes salt sensitivity of blood pressure because of impaired renal natriuretic capacity.

  9. findings implicate DNA methylation (show HELLS ELISA Kits) as a mechanism by which prenatal stress alters HSD11B2 gene expression

  10. This study found that 11beta-hydroxysteroid dehydrogenase type 2 knockout mice develop nephrogenic diabetes insipidus (show AVPR2 ELISA Kits).

Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) Antigen Profile

Antigen Summary

There are at least two isozymes of the corticosteroid 11-beta-dehydrogenase, a microsomal enzyme complex responsible for the interconversion of cortisol and cortisone. The type I isozyme has both 11-beta-dehydrogenase (cortisol to cortisone) and 11-oxoreductase (cortisone to cortisol) activities. The type II isozyme, encoded by this gene, has only 11-beta-dehydrogenase activity. In aldosterone-selective epithelial tissues such as the kidney, the type II isozyme catalyzes the glucocorticoid cortisol to the inactive metabolite cortisone, thus preventing illicit activation of the mineralocorticoid receptor. In tissues that do not express the mineralocorticoid receptor, such as the placenta and testis, it protects cells from the growth-inhibiting and/or pro-apoptotic effects of cortisol, particularly during embryonic development. Mutations in this gene cause the syndrome of apparent mineralocorticoid excess and hypertension.

Alternative names and synonyms associated with Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2)

  • hydroxysteroid (11-beta) dehydrogenase 2 (hsd11b2) Elisa Kit
  • hydroxysteroid (11-beta) dehydrogenase 2 (HSD11B2) Elisa Kit
  • hydroxysteroid 11-beta dehydrogenase 2 (Hsd11b2) Elisa Kit
  • NAD-dependent 11-beta-hydroxysteroid dehydrogenase (HSD11K) Elisa Kit
  • 11-HSD2 Elisa Kit
  • 11HSD2 Elisa Kit
  • AME Elisa Kit
  • AME1 Elisa Kit
  • HSD2 Elisa Kit
  • HSD11B2 Elisa Kit
  • HSD11K Elisa Kit
  • MGC81883 Elisa Kit
  • SDR9C3 Elisa Kit

Protein level used designations for HSD11B2

hydroxysteroid (11-beta) dehydrogenase 2 , corticosteroid 11-beta-dehydrogenase isozyme 2 , 11 beta-hydroxysteroid dehydrogenase type 2 , -HSD11 type II , 11-DH2 , 11-beta-HSD2 , 11-beta-hydroxysteroid dehydrogenase type 2 , 11-beta-hydroxysteroid dehydrogenase type II , NAD-dependent 11-beta-hydroxysteroid dehydrogenase , short chain dehydrogenase/reductase family 9C member 3 , 11-beta hydroxysteroid dehydrogenase , hydroxysteroid 11-beta dehydrogenase 2 , 11-beta-hydroxysteroid dehydrogenase 2 , 11(beta)-HSD2 , Hydroxysteroid dehydrogenase, 11 beta type 2

444491 Xenopus laevis
100034124 Equus caballus
100529249 Felis catus
3291 Homo sapiens
396948 Sus scrofa
282434 Bos taurus
100009531 Oryctolagus cuniculus
489758 Canis lupus familiaris
15484 Mus musculus
25117 Rattus norvegicus
443530 Ovis aries
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