Browse our anti-BMP4 (BMP4) Antibodies

Full name:
anti-Bone Morphogenetic Protein 4 Antibodies (BMP4)
On www.antibodies-online.com are 278 Bone Morphogenetic Protein 4 (BMP4) Antibodies from 32 different suppliers available. Additionally we are shipping BMP4 Kits (122) and BMP4 Proteins (75) and many more products for this protein. A total of 485 BMP4 products are currently listed.
Synonyms:
bmp-2, BMP-4, bmp2, bmp2-4, Bmp2b, Bmp2b-1, Bmp2b1, BMP4, BOMPR4A, cb670, MCOPS6, OFC11, XBMP-4, xbmp4, zbmp-2, zbmp-4, zbmp2, zgc:100779, ZYME
list all antibodies Gene Name GeneID UniProt
BMP4 652 P12644
BMP4 12159 P21275
BMP4 25296  

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anti-Human BMP4 Antibodies:

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Top referenced anti-BMP4 Antibodies

  1. Human Polyclonal BMP4 Primary Antibody for DB, EIA - ABIN492827 : Peng: The TGF-beta superfamily and its roles in the human ovary and placenta. in Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstétrique et gynécologie du Canada : JOGC 2003 (PubMed)
    Show all 4 references for 492827

  2. Human Monoclonal BMP4 Primary Antibody for WB - ABIN659071 : Kupfer, Anderson, Hooker, Skol, Kittles, Keku, Sandler, Ellis: Genetic heterogeneity in colorectal cancer associations between African and European americans. in Gastroenterology 2010 (PubMed)
    Show all 4 references for 659071

  3. Human Monoclonal BMP4 Primary Antibody for ELISA, WB - ABIN968986 : Oida, Iimura, Maruoka, Takeda, Sasaki: Cloning and sequence of bone morphogenetic protein 4 (BMP-4) from a human placental cDNA library. in DNA sequence : the journal of DNA sequencing and mapping 1995 (PubMed)
    Show all 3 references for 968986

  4. Human Polyclonal BMP4 Primary Antibody for IHC (p), WB - ABIN388454 : Sorescu, Sykes, Weiss, Platt, Saha, Hwang, Boyd, Boo, Vega, Taylor, Jo: Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress stimulates an inflammatory response. in The Journal of biological chemistry 2003 (PubMed)
    Show all 2 references for 388454

  5. Chicken Polyclonal BMP4 Primary Antibody for IHC, WB - ABIN223638 : Ni, Qiu, Rezvan, Kwon, Nam, Son, Visvader, Jo: Discovery of novel mechanosensitive genes in vivo using mouse carotid artery endothelium exposed to disturbed flow. in Blood 2010 (PubMed)
    Show all 2 references for 223638

  6. Mouse (Murine) Polyclonal BMP4 Primary Antibody for IF (p), IHC (p) - ABIN685642 : Wang, Zhao, Wang: Umbilical cord blood cells regulate the differentiation of endogenous neural stem cells in hypoxic ischemic neonatal rats via the hedgehog signaling pathway. in Brain research 2014 (PubMed)

  7. Cow (Bovine) Polyclonal BMP4 Primary Antibody for WB - ABIN2789354 : Ganti, Hunt, Parapuram, Hunt: Vitreous modulation of gene expression in low-passage human retinal pigment epithelial cells. in Investigative ophthalmology & visual science 2007 (PubMed)

More Antibodies against BMP4 Interaction Partners

Zebrafish Bone Morphogenetic Protein 4 (BMP4) interaction partners

  1. Study found that BMP-2 is negatively regulated by miR (show MYLIP Antibodies)-140 during early embryogenesis and bone development in zebra fi sh.

  2. Data show that transcription of organizer-specific bone morphogenetic protein 2b (bmp2b) is directly down-regulated by Nodal and up-regulated by Wnt (show WNT2 Antibodies) signal.

  3. Structures of Bmp2a (show BMP2 Antibodies), Bmp2b, Bmp4 and Bmp16 were found to be remarkably similar; with residues involved in receptor binding being highly conserved.

  4. FGF signaling in establishment of the developmental hematopoietic stem cell niche occurs via inhibition of bmp4 transcription, and activation of bmp antagonists, nog2 and grem1a (show GREM1 Antibodies).

  5. Organizer-derived Bmp2 is required for the formation of a correct Bmp activity gradient during embryonic development.

  6. BMP2b signaling in zebrafish embryos substantially decreases emergence of lymphatic endothelial cells.

  7. Data show that BMP2B protein is expressed in a gradient as early as blastula stages.

  8. we identify a previously unappreciated role for the Nodal-transcription factor FoxH1 in mediating cell responsiveness to Bmp further linking the control of these two pathways in the heart

  9. The Bmp2b mutants and mosaic loss-of-function experiments reveal that BMP acts as a repressor of eye-field fate through inhibition of its key transcription factor Rx3, thereby protecting the future telencephalon from acquiring eye identity.

  10. bmp2b is involved in dorsal retina initiation, acting upstream of gdf6a.

Xenopus laevis Bone Morphogenetic Protein 4 (BMP4) interaction partners

  1. Data indicate that bone morphogenetic protein (BMP) signaling is essential for erythroid differentiation, and in the absence of BMP signaling, precursor cells adopt an endothelial cell (EC) fate.

  2. Osr1 (show OSR1 Antibodies)/Osr2 normally repress bmp4 expression in the lateral plate mesoderm prior to respiratory specification.

  3. The results suggest that DeltaNp63 is an essential gene in early epidermal specification under the control of BMP4.

  4. PIAS (show PIAS1 Antibodies) proteins have differential ability to regulate signals from the growth factors activin (show Actbeta Antibodies), bone morphogenetic protein 4 (BMP4), and Wnt8 (show WNT8A Antibodies).

  5. Data show that PV.1A undergoes combinatorial regulation during early Xenopus development as both the direct target of BMP-4 signaling and as the direct and indirect target of positive and negative regulatory factors.

  6. BMP inhibition is sufficient for neural induction in vivo, and that in the absence of ventral BMPs, Spemann organizer signals are not required for brain formation.

  7. Data suggest that the feedback inhibitors BAMBI (show BAMBI Antibodies), SMAD6 (show SMAD6 Antibodies), and SMAD7 (show SMAD7 Antibodies) expand the dynamic BMP4 signaling range essential for proper embryonic patterning and reduce interindividual phenotypic and molecular variability in Xenopus embryos.

  8. limits homeobox (show PRRX1 Antibodies) gene expression in the organiser/non-organiser direction

  9. X-epilectin expression is down-regulated by Noggin (show NOG Antibodies) and tBR and that this effect is inhibited by BMP4 over-expression

  10. BMP4-dependent expression of Xenopus Grainyhead-like 1 (show GRHL1 Antibodies) has a critical role in epidermal differentiation

Horse (Equine) Bone Morphogenetic Protein 4 (BMP4) interaction partners

  1. BMP4 signaling plays a role in the regulation of terminal differentiation of primary equine trophoblast cells via activation of the SMAD1 (show SMAD1 Antibodies)/5 pathway

Human Bone Morphogenetic Protein 4 (BMP4) interaction partners

  1. Study shows that BMP4 is overexpressed in hepatocellular carcinoma (HCC (show FAM126A Antibodies)) tissues and BMP4-induced ID2/CDKN1B (show CDKN1B Antibodies) signaling facilitates the proliferation of HCC (show FAM126A Antibodies).

  2. Data suggest pituitary cells secrete factor (TSP1) that binds to and inhibits action of BMP2 and BMP4; von Willebrand type C domain of TSP1 is likely responsible for this BMP2/4-binding activity. These studies were initially conducted using cultured cells from ovine pituitary gland and mouse cell line; interactions were confirmed using recombinant human proteins. (TSP1 = thrombospondin-1; BMP = bone morphogenetic protein)

  3. we demonstrate that expression of bone morphogenetic protein 4 (BMP-4) is universally upregulated in human colorectal cancer cells and tissues, resulting in activated BMP signaling

  4. RUNX1T1 (show RUNX1T1 Antibodies) serves as a common angiogenic driver for vaculogenesis and functionality of endothelial lineage cells

  5. Phosphorylated Smad1/5/8/9 specifically bound to the BREs of Smad8/9 gene. The present study reveals that Smad8/9 is a unique R-Smad regulated through the BMP pathway at the mRNA level.

  6. Meta-analysis to assess the effect of BMP4 rs17563 polymorphism on nonsyndromic cleft lip with or without cleft palate (NSCL (show NHLH1 Antibodies)/P) suggests that the C allele of BMP4 rs17563 may be a risk factor for NSCL (show NHLH1 Antibodies)/P among Asians and Caucasians, and may be a protective factor for NSCL (show NHLH1 Antibodies)/P in Brazilian population.

  7. this study identified BMP-4 as a potential molecular marker for predicting the invasion and progression of papillary thyroid carcinoma

  8. Bmp4 drives terminal differentiation into mature white rather than brown fat cells. Bmp4 seems to have a dual role in metabolism either promoting or repressing oxidative metabolism in a cell context dependent manner.

  9. Data suggest that serum BMP4 levels are associated with visceral adiposity and may play role in fat distribution; role of BMP4 in males and females may be different; visceral adiposity may predict serum BMP4 levels in females with obesity; serum BMP4 levels are decreased after GLP-1 receptor (show GLP1R Antibodies) agonist (exenatide) treatment in obesity. This study was conducted in China.

  10. BMP4 is a potential cause of digital and eye abnormalities in familial dopa-responsive dystonia.

Mouse (Murine) Bone Morphogenetic Protein 4 (BMP4) interaction partners

  1. These results suggest how BMP4 regulates adipocyte recruitment in subcutaneous (SC) white adipose tissue, and thus promote its beneficial metabolic effects.

  2. RUNX1T1 (show RUNX1T1 Antibodies) serves as a common angiogenic driver for vaculogenesis and functionality of endothelial lineage cells

  3. Expression of Bmp4 in the ureteric mesenchyme depends on HH signaling and Foxf1 (show FOXF1 Antibodies), and that exogenous BMP4 rescued cell proliferation and epithelial differentiation in ureters with abrogated HH signaling or FOXF1 (show FOXF1 Antibodies) function.

  4. the effect of titanium (Ti) with nanotopography (Nano) on the endogenous expression of BMP-2 (show BMP2 Antibodies) and BMP-4 and the relevance of this process to the nanotopography-induced osteoblast differentiation.

  5. These data indicate that Foxc1 (show FOXC1 Antibodies) expression is regulated by BMP4 and FOXC1 (show FOXC1 Antibodies) functions in the commitment of progenitor cells to the osteoblast fate and its expression is reduced when differentiation proceeds.

  6. Phosphorylated Smad1/5/8/9 specifically bound to the BREs of Smad8/9 gene. The present study reveals that Smad8/9 is a unique R-Smad regulated through the BMP pathway at the mRNA level.

  7. Treatment of ES cells with TPO (show THPO Antibodies) induced the autocrine production of BMP4 with concomitant upregulation of the BMP receptor BMPR1A (show BMPR1A Antibodies), phosphorylation of SMAD1 (show SMAD1 Antibodies), 5, 8, and activation of specific BMP4 target genes; this was mediated by TPO (show THPO Antibodies)-dependent binding of transcription factor HIF-1alpha (show HIF1A Antibodies) to the BMP4 gene promoter.

  8. Data suggest that ovarian Bmp4 levels are significantly decreased in a mouse model of polycystic ovary syndrome with hyperandrogenism; androgens inhibited Bmp4 expression via activation of androgen receptors; Smad4 (show SMAD4 Antibodies) signaling rather than p38 MAPK (show MAPK14 Antibodies) pathway regulates androgen and estrogen formation.

  9. tightly spatial interaction of FSTL1 (show FSTL1 Antibodies) and BMP4 signaling plays an essential role in lung development

  10. this study identified Bmp4 as a significant factor for improved maintenance of Foxn1 (show FOXN2 Antibodies) expression, promotion of thymic epithelial progenitor populations self-renewal and immature epithelial cell differentiation and survival

Cow (Bovine) Bone Morphogenetic Protein 4 (BMP4) interaction partners

  1. Bone morphogenetic protein 4 and retinoic acid trigger bovine VASA homolog (show DDX4 Antibodies) expression in differentiating bovine induced pluripotent stem cells.

  2. The BMP2/4 ligand and receptor system presides within bovine trophectoderm prior to uterine attachment. BMP4 negatively impacts CT1 (show SLC6A8 Antibodies) cell growth

  3. BMP4 during maturation increased the proportion of Oct-4 (show POU5F1 Antibodies) positive cells in parthenogenic embryos. BMP4 is implicated in bovine oocytes maturation and embryo development.

  4. analysis of polymorphic CA microsatellites in the third exon of the bovine BMP4 gene

  5. concluded that a bone morphogenetic protein (BMP)-signaling system, consisting of BMP2, BMP4, type II and I receptors, is present in bovine antral follicles and plays a role in development and functioning of follicles rather than in oocyte maturation

  6. Data report that BMP-7 (show BMP7 Antibodies) suppresses granulosa cell apoptosis by inhibiting the release of caspase-activated DNase (CAD (show DFFB Antibodies)) via a mechanism which does not appear to be associated with the mitochondrial pathway, whereas BMP-4 inhibits the release of CAD (show CAD Antibodies).

  7. Heat shock protein 70 (show HSP70 Antibodies) enhances vascular bone morphogenetic protein-4 signaling by binding matrix Gla protein (show MGP Antibodies).

Goat Bone Morphogenetic Protein 4 (BMP4) interaction partners

  1. A microsatellite (ACn (show ACIN1 Antibodies)) was identified in the 3' UTR (show UTS2R Antibodies) of BMP4 gene.Prolificacy associated microsatellite (AC19 (show POLR1D Antibodies)) was detected in Indian goats.

Pig (Porcine) Bone Morphogenetic Protein 4 (BMP4) interaction partners

  1. paracrine signals from the embryo, represented by FGF4 (show FGF4 Antibodies) and BMP4, induce a response in the trophoblast prior to the extensive elongation.

  2. The structure of porcine BMP4 gene is highly conservative with other mammalian BMP4 genes, but some differences may be present in the regulation of gene expression.

  3. Altered shear stress stimulates upregulation of endothelial VCAM-1 (show VCAM1 Antibodies) and ICAM-1 (show ICAM1 Antibodies) in a BMP-4- and TGF-beta1 (show TGFB1 Antibodies)-dependent pathway.

Rabbit Bone Morphogenetic Protein 4 (BMP4) interaction partners

  1. The TM-induced characteristic changes in the expression pattern of Hoxa11 (show HOXA11 Antibodies) and Bmp4 on GDs (show PAEP Antibodies) 10 and/or 11 were not noted.

  2. BMP4 is expressed peripherally in hypoblast and epiblast and in the mesoderm at the posterior pole of the embryonic disc.

  3. Data show that BMP-2 (show BMP2 Antibodies), BMP-4, and BMP-7 (show BMP7 Antibodies), noggin (show NOG Antibodies), and chordin (show CHRD Antibodies) were colocalized in rimming osteoblasts, osteoclasts, and chondrocytes.

  4. Both of the adenovirus-containing bone morphogenetic protein transduced MSCs expressed BMP4 mRNA and protein and underwent osteogenic differentiation.

BMP4 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.

Alternative names and synonyms associated with BMP4

  • bone morphogenetic protein 4 (bmp4) antibody
  • bone morphogenetic protein 4 (bmp4-a) antibody
  • bone morphogenetic protein 4 (BMP4) antibody
  • Bone morphogenetic protein 4 (bmp4) antibody
  • bone morphogenetic protein 4 (LOC100286408) antibody
  • bone morphogenetic protein 2b (bmp2b) antibody
  • bone morphogenetic protein 4 (bmp4-b) antibody
  • bone morphogenetic protein 4 (Bmp4) antibody
  • bmp-2 antibody
  • BMP-4 antibody
  • bmp2 antibody
  • bmp2-4 antibody
  • Bmp2b antibody
  • Bmp2b-1 antibody
  • Bmp2b1 antibody
  • BMP4 antibody
  • BOMPR4A antibody
  • cb670 antibody
  • MCOPS6 antibody
  • OFC11 antibody
  • XBMP-4 antibody
  • xbmp4 antibody
  • zbmp-2 antibody
  • zbmp-4 antibody
  • zbmp2 antibody
  • zgc:100779 antibody
  • ZYME antibody

Protein level used designations for BMP4

etID309887.17 , bone morphogenetic protein-4 , bone morphogenetic protein 4 , bone morphogenetic protein 4, isoform 3 , Bone morphogenetic protein 4 , bone morphogenetic protein 4-like , bone morphogenetic protein 2 , etID309839.20 , swirl , swr , BMP-2B , BMP-4 , bone morphogenetic protein 2B

GENE ID SPECIES
30612 Danio rerio
397874 Xenopus laevis
452912 Pan troglodytes
549788 Xenopus (Silurana) tropicalis
100034048 Equus caballus
100049354 Oryzias latipes
100137596 Papio anubis
100194815 Salmo salar
100221891 Taeniopygia guttata
100398270 Callithrix jacchus
100286408 Salmo salar
100449444 Pongo abelii
30632 Danio rerio
652 Homo sapiens
399322 Xenopus laevis
12159 Mus musculus
25296 Rattus norvegicus
407216 Bos taurus
490695 Canis lupus familiaris
100860789 Capra hircus
100113425 Sus scrofa
396165 Gallus gallus
100009569 Oryctolagus cuniculus
100733516 Cavia porcellus
443502 Ovis aries
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