Browse our anti-BMP4 (BMP4) Antibodies

Full name:
anti-Bone Morphogenetic Protein 4 Antibodies (BMP4)
On www.antibodies-online.com are 273 Bone Morphogenetic Protein 4 (BMP4) Antibodies from 30 different suppliers available. Additionally we are shipping BMP4 Kits (120) and BMP4 Proteins (69) and many more products for this protein. A total of 472 BMP4 products are currently listed.
Synonyms:
bmp-2, BMP-4, bmp2, bmp2-4, Bmp2b, Bmp2b-1, Bmp2b1, BMP4, BOMPR4A, cb670, MCOPS6, OFC11, XBMP-4, xbmp4, zbmp-2, zbmp-4, zbmp2, zgc:100779, ZYME
list all antibodies Gene Name GeneID UniProt
BMP4 652 P12644
BMP4 12159 P21275
BMP4 25296  

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Most Popular Reactivities for anti-BMP4 (BMP4) Antibodies

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anti-Human BMP4 Antibodies:

anti-Mouse (Murine) BMP4 Antibodies:

anti-Rat (Rattus) BMP4 Antibodies:

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Top referenced anti-BMP4 Antibodies

  1. Human Polyclonal BMP4 Primary Antibody for DB, EIA - ABIN492827 : Peng: The TGF-beta superfamily and its roles in the human ovary and placenta. in Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstétrique et gynécologie du Canada : JOGC 2003 (PubMed)
    Show all 4 references for 492827

  2. Human Monoclonal BMP4 Primary Antibody for WB - ABIN659071 : Kupfer, Anderson, Hooker, Skol, Kittles, Keku, Sandler, Ellis: Genetic heterogeneity in colorectal cancer associations between African and European americans. in Gastroenterology 2010 (PubMed)
    Show all 4 references for 659071

  3. Human Monoclonal BMP4 Primary Antibody for ELISA, WB - ABIN968986 : Oida, Iimura, Maruoka, Takeda, Sasaki: Cloning and sequence of bone morphogenetic protein 4 (BMP-4) from a human placental cDNA library. in DNA sequence : the journal of DNA sequencing and mapping 1995 (PubMed)
    Show all 3 references for 968986

  4. Chicken Polyclonal BMP4 Primary Antibody for IHC, WB - ABIN223638 : Ni, Qiu, Rezvan, Kwon, Nam, Son, Visvader, Jo: Discovery of novel mechanosensitive genes in vivo using mouse carotid artery endothelium exposed to disturbed flow. in Blood 2010 (PubMed)
    Show all 2 references for 223638

  5. Human Polyclonal BMP4 Primary Antibody for IHC (p), WB - ABIN388454 : Sorescu, Sykes, Weiss, Platt, Saha, Hwang, Boyd, Boo, Vega, Taylor, Jo: Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress stimulates an inflammatory response. in The Journal of biological chemistry 2003 (PubMed)
    Show all 2 references for 388454

  6. Mouse (Murine) Polyclonal BMP4 Primary Antibody for IF (p), IHC (p) - ABIN685642 : Wang, Zhao, Wang: Umbilical cord blood cells regulate the differentiation of endogenous neural stem cells in hypoxic ischemic neonatal rats via the hedgehog signaling pathway. in Brain research 2014 (PubMed)

  7. Cow (Bovine) Polyclonal BMP4 Primary Antibody for WB - ABIN2789354 : Ganti, Hunt, Parapuram, Hunt: Vitreous modulation of gene expression in low-passage human retinal pigment epithelial cells. in Investigative ophthalmology & visual science 2007 (PubMed)

More Antibodies against BMP4 Interaction Partners

Zebrafish Bone Morphogenetic Protein 4 (BMP4) interaction partners

  1. Study found that BMP-2 is negatively regulated by miR (show MYLIP Antibodies)-140 during early embryogenesis and bone development in zebra fi sh.

  2. Data show that transcription of organizer-specific bone morphogenetic protein 2b (bmp2b) is directly down-regulated by Nodal and up-regulated by Wnt (show WNT2 Antibodies) signal.

  3. Structures of Bmp2a (show BMP2 Antibodies), Bmp2b, Bmp4 and Bmp16 were found to be remarkably similar; with residues involved in receptor binding being highly conserved.

  4. FGF signaling in establishment of the developmental hematopoietic stem cell niche occurs via inhibition of bmp4 transcription, and activation of bmp antagonists, nog2 and grem1a (show GREM1 Antibodies).

  5. Organizer-derived Bmp2 is required for the formation of a correct Bmp activity gradient during embryonic development.

  6. BMP2b signaling in zebrafish embryos substantially decreases emergence of lymphatic endothelial cells.

  7. Data show that BMP2B protein is expressed in a gradient as early as blastula stages.

  8. we identify a previously unappreciated role for the Nodal-transcription factor FoxH1 in mediating cell responsiveness to Bmp further linking the control of these two pathways in the heart

  9. The Bmp2b mutants and mosaic loss-of-function experiments reveal that BMP acts as a repressor of eye-field fate through inhibition of its key transcription factor Rx3, thereby protecting the future telencephalon from acquiring eye identity.

  10. bmp2b is involved in dorsal retina initiation, acting upstream of gdf6a.

Xenopus laevis Bone Morphogenetic Protein 4 (BMP4) interaction partners

  1. Data indicate that bone morphogenetic protein (BMP) signaling is essential for erythroid differentiation, and in the absence of BMP signaling, precursor cells adopt an endothelial cell (EC) fate.

  2. Osr1 (show OSR1 Antibodies)/Osr2 normally repress bmp4 expression in the lateral plate mesoderm prior to respiratory specification.

  3. The results suggest that DeltaNp63 is an essential gene in early epidermal specification under the control of BMP4.

  4. PIAS (show PIAS1 Antibodies) proteins have differential ability to regulate signals from the growth factors activin (show Actbeta Antibodies), bone morphogenetic protein 4 (BMP4), and Wnt8 (show WNT8A Antibodies).

  5. Data show that PV.1A undergoes combinatorial regulation during early Xenopus development as both the direct target of BMP-4 signaling and as the direct and indirect target of positive and negative regulatory factors.

  6. BMP inhibition is sufficient for neural induction in vivo, and that in the absence of ventral BMPs, Spemann organizer signals are not required for brain formation.

  7. Data suggest that the feedback inhibitors BAMBI (show BAMBI Antibodies), SMAD6 (show SMAD6 Antibodies), and SMAD7 (show SMAD7 Antibodies) expand the dynamic BMP4 signaling range essential for proper embryonic patterning and reduce interindividual phenotypic and molecular variability in Xenopus embryos.

  8. limits homeobox (show PRRX1 Antibodies) gene expression in the organiser/non-organiser direction

  9. X-epilectin expression is down-regulated by Noggin (show NOG Antibodies) and tBR and that this effect is inhibited by BMP4 over-expression

  10. BMP4-dependent expression of Xenopus Grainyhead-like 1 (show GRHL1 Antibodies) has a critical role in epidermal differentiation

Horse (Equine) Bone Morphogenetic Protein 4 (BMP4) interaction partners

  1. BMP4 signaling plays a role in the regulation of terminal differentiation of primary equine trophoblast cells via activation of the SMAD1 (show SMAD1 Antibodies)/5 pathway

Human Bone Morphogenetic Protein 4 (BMP4) interaction partners

  1. Data suggest that serum BMP4 levels are associated with visceral adiposity and may play role in fat distribution; role of BMP4 in males and females may be different; visceral adiposity may predict serum BMP4 levels in females with obesity; serum BMP4 levels are decreased after GLP-1 receptor (show GLP1R Antibodies) agonist (exenatide) treatment in obesity. This study was conducted in China.

  2. BMP4 is a potential cause of digital and eye abnormalities in familial dopa-responsive dystonia.

  3. BMP4 expression was significantly upregulated in esophageal adenocarcinoma and Barrett's esophagus. BMP4 incubation inhibited cell viability,induced cell migration adnd upregulated SNAIL2 expression.

  4. the data identify MxA (show MX1 Antibodies) as a novel stimulator of BMP4 and BMP9 (show GDF2 Antibodies) transcriptional signaling, and suggest it to be a candidate IFN-alpha (show IFNA Antibodies)-inducible mechanism that might have a protective role against development of pulmonary arterial hypertension and other vascular diseases.

  5. The 6007C>T polymorphism of BMP-4, -66T>G polymorphism of OPN (show SPP1 Antibodies), and VDR (show CYP27B1 Antibodies)-FokI polymorphism are the susceptible factors of spinal TB and indicators of the clinical severity. These three genes may collaborate in the development of spinal TB.

  6. The results suggest that Osterix (show SP7 Antibodies) plays an important role in increasing BMP- 4-induced Cx43 (show GJA1 Antibodies) activity.

  7. inhibitory role on glucagon (show GCG Antibodies) secretion, pancreatic alpha-cell growth, and expression of genes maintaining alpha-cell identity

  8. BMP4 promotes a phenotype change of an esophageal squamous epithelium via up-regulation of KLF4 (show KLF4 Antibodies).

  9. Study demonstrated that Chrdl1 (show CHRDL1 Antibodies) acts as an inhibitor of BMP4-induced migration and invasion which stimulated breast cancer cell invasion and matrix degradation, in part, through MMP2 (show MMP2 Antibodies) and MMP9 (show MMP9 Antibodies) activity that is antagonized by Chrdl1 (show CHRDL1 Antibodies).

  10. the upregulation of autophagy-related gene (Atg) and wingless/int1 (show WNT1 Antibodies) (Wnt (show WNT2 Antibodies)) signaling during BMP-2 (show BMP2 Antibodies)-mediated human osteoblastic differentiation, was examined.

Mouse (Murine) Bone Morphogenetic Protein 4 (BMP4) interaction partners

  1. Treatment of ES cells with TPO (show THPO Antibodies) induced the autocrine production of BMP4 with concomitant upregulation of the BMP receptor BMPR1A (show BMPR1A Antibodies), phosphorylation of SMAD1 (show SMAD1 Antibodies), 5, 8, and activation of specific BMP4 target genes; this was mediated by TPO (show THPO Antibodies)-dependent binding of transcription factor HIF-1alpha (show HIF1A Antibodies) to the BMP4 gene promoter.

  2. Data suggest that ovarian Bmp4 levels are significantly decreased in a mouse model of polycystic ovary syndrome with hyperandrogenism; androgens inhibited Bmp4 expression via activation of androgen receptors; Smad4 (show SMAD4 Antibodies) signaling rather than p38 MAPK (show MAPK14 Antibodies) pathway regulates androgen and estrogen formation.

  3. tightly spatial interaction of FSTL1 (show FSTL1 Antibodies) and BMP4 signaling plays an essential role in lung development

  4. this study identified Bmp4 as a significant factor for improved maintenance of Foxn1 (show FOXN2 Antibodies) expression, promotion of thymic epithelial progenitor populations self-renewal and immature epithelial cell differentiation and survival

  5. these data reveal a novel mechanism that the Bmp4-Msx1 (show MSX1 Antibodies) pathway and Osr2 control tooth organogenesis through antagonistic regulation of expression of secreted Wnt (show WNT2 Antibodies) antagonists.

  6. inhibitory role on glucagon (show GCG Antibodies) secretion, pancreatic alpha-cell growth, and expression of genes maintaining alpha-cell identity

  7. We demonstrate that elevated BMP4 depletes PSM progenitors in vitro, phenocopying the Fgf3 mutant, suggesting that excessive BMP signals cause the Fgf3 axis defect. To test this in vivo we increased BMP signaling in Fgf3 mutants by removing one copy of Noggin, which encodes a BMP antagonist.

  8. BMP-4 inhibited insulin (show INS Antibodies) signaling through activation of PKC-theta (show PRKCQ Antibodies); isoform, and resulted in insulin (show INS Antibodies) resistance through the attenuation of insulin (show INS Antibodies) signaling

  9. Western blot analysis demonstrated that following BMP2 (show BMP2 Antibodies) and BMP7 (show BMP7 Antibodies) cotransfection of MC3T3E1 cells, the protein expression levels of BMP2 (show BMP2 Antibodies), BMP4, BMP6 (show BMP6 Antibodies), BMP7 (show BMP7 Antibodies), BMP9 (show GDF2 Antibodies) and Wnt3a (show WNT3A Antibodies) were increased compared with control cells

  10. BMP4 inhibited ERalpha (show ESR1 Antibodies) signaling by increasing the degradation of ERalpha (show ESR1 Antibodies), and that the expression of BMP4 itself was suppressed by estrogens.

Cow (Bovine) Bone Morphogenetic Protein 4 (BMP4) interaction partners

  1. Bone morphogenetic protein 4 and retinoic acid trigger bovine VASA homolog (show DDX4 Antibodies) expression in differentiating bovine induced pluripotent stem cells.

  2. The BMP2/4 ligand and receptor system presides within bovine trophectoderm prior to uterine attachment. BMP4 negatively impacts CT1 (show SLC6A8 Antibodies) cell growth

  3. BMP4 during maturation increased the proportion of Oct-4 (show POU5F1 Antibodies) positive cells in parthenogenic embryos. BMP4 is implicated in bovine oocytes maturation and embryo development.

  4. analysis of polymorphic CA microsatellites in the third exon of the bovine BMP4 gene

  5. concluded that a bone morphogenetic protein (BMP)-signaling system, consisting of BMP2, BMP4, type II and I receptors, is present in bovine antral follicles and plays a role in development and functioning of follicles rather than in oocyte maturation

  6. Data report that BMP-7 (show BMP7 Antibodies) suppresses granulosa cell apoptosis by inhibiting the release of caspase-activated DNase (CAD (show DFFB Antibodies)) via a mechanism which does not appear to be associated with the mitochondrial pathway, whereas BMP-4 inhibits the release of CAD (show CAD Antibodies).

  7. Heat shock protein 70 (show HSP70 Antibodies) enhances vascular bone morphogenetic protein-4 signaling by binding matrix Gla protein (show MGP Antibodies).

Goat Bone Morphogenetic Protein 4 (BMP4) interaction partners

  1. A microsatellite (ACn (show ACIN1 Antibodies)) was identified in the 3' UTR (show UTS2R Antibodies) of BMP4 gene.Prolificacy associated microsatellite (AC19 (show POLR1D Antibodies)) was detected in Indian goats.

Pig (Porcine) Bone Morphogenetic Protein 4 (BMP4) interaction partners

  1. paracrine signals from the embryo, represented by FGF4 (show FGF4 Antibodies) and BMP4, induce a response in the trophoblast prior to the extensive elongation.

  2. The structure of porcine BMP4 gene is highly conservative with other mammalian BMP4 genes, but some differences may be present in the regulation of gene expression.

  3. Altered shear stress stimulates upregulation of endothelial VCAM-1 (show VCAM1 Antibodies) and ICAM-1 (show ICAM1 Antibodies) in a BMP-4- and TGF-beta1 (show TGFB1 Antibodies)-dependent pathway.

Rabbit Bone Morphogenetic Protein 4 (BMP4) interaction partners

  1. The TM-induced characteristic changes in the expression pattern of Hoxa11 (show HOXA11 Antibodies) and Bmp4 on GDs (show PAEP Antibodies) 10 and/or 11 were not noted.

  2. BMP4 is expressed peripherally in hypoblast and epiblast and in the mesoderm at the posterior pole of the embryonic disc.

  3. Data show that BMP-2 (show BMP2 Antibodies), BMP-4, and BMP-7 (show BMP7 Antibodies), noggin (show NOG Antibodies), and chordin (show CHRD Antibodies) were colocalized in rimming osteoblasts, osteoclasts, and chondrocytes.

  4. Both of the adenovirus-containing bone morphogenetic protein transduced MSCs expressed BMP4 mRNA and protein and underwent osteogenic differentiation.

BMP4 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.

Alternative names and synonyms associated with BMP4

  • bone morphogenetic protein 4 (bmp4) antibody
  • bone morphogenetic protein 4 (bmp4-a) antibody
  • bone morphogenetic protein 4 (BMP4) antibody
  • Bone morphogenetic protein 4 (bmp4) antibody
  • bone morphogenetic protein 4 (LOC100286408) antibody
  • bone morphogenetic protein 2b (bmp2b) antibody
  • bone morphogenetic protein 4 (bmp4-b) antibody
  • bone morphogenetic protein 4 (Bmp4) antibody
  • bmp-2 antibody
  • BMP-4 antibody
  • bmp2 antibody
  • bmp2-4 antibody
  • Bmp2b antibody
  • Bmp2b-1 antibody
  • Bmp2b1 antibody
  • BMP4 antibody
  • BOMPR4A antibody
  • cb670 antibody
  • MCOPS6 antibody
  • OFC11 antibody
  • XBMP-4 antibody
  • xbmp4 antibody
  • zbmp-2 antibody
  • zbmp-4 antibody
  • zbmp2 antibody
  • zgc:100779 antibody
  • ZYME antibody

Protein level used designations for BMP4

etID309887.17 , bone morphogenetic protein-4 , bone morphogenetic protein 4 , bone morphogenetic protein 4, isoform 3 , Bone morphogenetic protein 4 , bone morphogenetic protein 4-like , bone morphogenetic protein 2 , etID309839.20 , swirl , swr , BMP-2B , BMP-4 , bone morphogenetic protein 2B

GENE ID SPECIES
30612 Danio rerio
397874 Xenopus laevis
452912 Pan troglodytes
549788 Xenopus (Silurana) tropicalis
100034048 Equus caballus
100049354 Oryzias latipes
100137596 Papio anubis
100194815 Salmo salar
100221891 Taeniopygia guttata
100398270 Callithrix jacchus
100286408 Salmo salar
100449444 Pongo abelii
30632 Danio rerio
652 Homo sapiens
399322 Xenopus laevis
12159 Mus musculus
25296 Rattus norvegicus
407216 Bos taurus
490695 Canis lupus familiaris
100860789 Capra hircus
100113425 Sus scrofa
396165 Gallus gallus
100009569 Oryctolagus cuniculus
100733516 Cavia porcellus
443502 Ovis aries
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