Browse our CHRM3 Proteins (CHRM3)

Full name:
Cholinergic Receptor, Muscarinic 3 Proteins (CHRM3)
On www.antibodies-online.com are 6 Cholinergic Receptor, Muscarinic 3 (CHRM3) Proteins from 2 different suppliers available. Additionally we are shipping CHRM3 Antibodies (105) and CHRM3 Kits (33) and many more products for this protein. A total of 146 CHRM3 products are currently listed.
Synonyms:
Chrm-3, EGBRS, HM3, M3, M3R, MACHR
list all proteins Gene Name GeneID UniProt
CHRM3 1131 P20309
Rat CHRM3 CHRM3 24260 P08483
CHRM3 12671 Q9ERZ3

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CHRM3 Proteins (CHRM3) by Origin

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More Proteins for CHRM3 Interaction Partners

Human Cholinergic Receptor, Muscarinic 3 (CHRM3) interaction partners

  1. this study shows that anti-M3R (show CHRM4 Proteins) is significantly elevated in Sjogren's syndrome plasma in comparison with rheumatoid arthritis, systemic lupus erythematosus, and healthy controls

  2. Interacting post-muscarinic receptor (show CHRM5 Proteins) signaling pathways potentiate MMP1 (show MMP1 Proteins) expression and invasion of human colon cancer cells.

  3. M3R (show CHRM4 Proteins) expression plays an important role in early progression and invasion of colon neoplasia but is less important once tumors have spread.

  4. This study presents the endocytic pathways of internalization for muscarinic type 3 receptor and flotillin-1 (show FLOT1 Proteins)/2 in salivary gland epithelial cells. knockdown of flot-1 (show FLOT1 Proteins) or -2 by flotillin (show FLOT2 Proteins)-specific siRNA prevented internalization and reduced the endocytic efficiency of muscarinic type 3 receptor.

  5. M3-mAChR activation leads to enhancement of hsp expression via PKC (show PRRT2 Proteins)-dependent phosphorylation of HSF1 (show HSF1 Proteins), thereby stabilizing the mutant hERG (show KCNH2 Proteins)-FLAG protein. Thus, M3-mAChR activators may have a therapeutic value for patients with LQT2 (show KCNH2 Proteins).

  6. There were no significant associations between CHRM3 SNPs and autonomic nervous system activity in patients with schizophrenia on high-dose antipsychotics.

  7. To our knowledge, this is the first genetic association study that reveals the genetic contribution of CHRM3 gene in bladder cancer etiology.

  8. The CHRM3 gene plays a role in abnormal thalamo-orbital frontal cortex functional connectivity in first-episode treatment-naive patients with schizophrenia.

  9. These findings indicate that M3 mAChR may be important therapeutic target for obstructive airway diseases, as it regulates the effects of the epithelial-derived chemokines on ASM (show SMPD1 Proteins) cell migration, which results in lung remodeling.

  10. Blockading CHRM3 by shRNA or treatment with darifenacin inhibited prostate cancer growth.

Pig (Porcine) Cholinergic Receptor, Muscarinic 3 (CHRM3) interaction partners

  1. Data suggest that both M(2) and M(3) muscarinic receptors mediate the contraction in both pig clasp (show CLASRP Proteins) and sling fibers similar to human clasp (show CLASRP Proteins) and sling fibers.

Cow (Bovine) Cholinergic Receptor, Muscarinic 3 (CHRM3) interaction partners

  1. Sequential activation of muscarinic M3 receptors and cannabinoid CB1 receptors produce synergistic contractile effects of the bovine ciliary muscle by involving the activation of Rho-kinase and protein kinase C.

  2. These data support the existence of a novel transducing cascade, involving Galpha (show SUCLG1 Proteins)(q16)beta gamma coupling M(3)AChR to NPR (show NPTXR Proteins)-GC.

  3. airway M(2)Rs inhibit BK channels by a dual, Gbetagamma-mediated mechanism, a direct membrane-delimited interaction, and the activation of the phospholipase C/protein kinase C pathway

Mouse (Murine) Cholinergic Receptor, Muscarinic 3 (CHRM3) interaction partners

  1. Arthritis-induced joint destruction was significantly stronger in mice with M3 muscarinic acetylcholine receptor deficiency.

  2. The effects of muscarinic receptor (show CHRM5 Proteins) M3 knockout on cathepsin K (show CTSK Proteins) expression, bone density and biomechanical properties of bone are reported.

  3. results suggest that the autoantibodies against peptides of the second extracellular loop of M3R are not pathogenic in vivo and they are not suitable as biomarkers for pSS (show CDSN Proteins) diagnosis

  4. Expression of the M3 receptors mediating cholinergic contractile stimuli of the detrusor muscle was dysregulated in both Mras (show MRAS Proteins)-/- males and females, although only males exhibited a urinary phenotype.

  5. The study screened CrkL (show CRKL Proteins) binding proteins using RNA interference (RNAi) and identified Sorbs1 (show SORBS1 Proteins) and Sorbs2 (show Sorbs2 Proteins) as two proteins that are enriched at AChR clusters and are required for the formation of AChR aggregation in vitro.

  6. Activation of Chrm3 inhibits the recruitment of beta-arrestin-2 (show ARRB2 Proteins) to odorant receptors, resulting in a potentiation of odor-induced responses in olfactory sensory neurons.

  7. The muscarinic M3R receptor interacts directly with NOSTRIN (show NOSTRIN Proteins) at the plasma membrane in the aorta.

  8. Cholinergic signalling via the M3R is essential for optimal Th1 (show HAND1 Proteins) and Th2 adaptive immunity to infection.

  9. Our results identify a novel candidate mouse gene, Zfp277, whose expression pattern is compatible with a role in mediating divergent effects of Chrm3 and Chrm1 (show CHRM1 Proteins) gene ablation on murine intestinal neoplasia.

  10. In this review, genetic modifications of muscarinic M3 receptor cause robust alterations in insulin (show INS Proteins) levels and glucose tolerance.

CHRM3 Protein Profile

Protein Summary

G-protein coupled receptor, muscarinic receeptor subtype that mediates cholinergic-induced contraction in most smooth muscle

Alternative names and synonyms associated with CHRM3

  • cholinergic receptor, muscarinic 3 (CHRM3)
  • cholinergic receptor, muscarinic 3 (LOC100218380)
  • cholinergic receptor, muscarinic 3 (LOC100355313)
  • cholinergic receptor, muscarinic 3 (Chrm3)
  • cholinergic receptor, muscarinic 3, cardiac (Chrm3)
  • Chrm-3 protein
  • EGBRS protein
  • HM3 protein
  • M3 protein
  • M3R protein
  • MACHR protein

Protein level used designations for CHRM3

m3 muscarinic acetylcholine receptor , muscarinic acetylcholine receptor M3 , cholinergic receptor, muscarinic 3 , acetylcholine receptor, muscarinic 3 , m3 muscarinic receptor , cholinergic receptor, muscarinic 3, cardiac , M3 muscarinic acetylcholine receptor , AChR M3 , mm3 mAChR , muscarinic acetylcholine receptor 3

GENE ID SPECIES
403827 Canis lupus familiaris
708901 Macaca mulatta
100218380 Taeniopygia guttata
100355313 Oryctolagus cuniculus
100597211 Nomascus leucogenys
1131 Homo sapiens
24260 Rattus norvegicus
100144478 Sus scrofa
281685 Bos taurus
396364 Gallus gallus
100172838 Pongo abelii
469725 Pan troglodytes
12671 Mus musculus
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