Browse our CHRNB1 Proteins (CHRNB1)

Full name:
Cholinergic Receptor, Nicotinic, beta 1 (Muscle) Proteins (CHRNB1)
On www.antibodies-online.com are 8 Cholinergic Receptor, Nicotinic, beta 1 (Muscle) (CHRNB1) Proteins from 3 different suppliers available. Additionally we are shipping CHRNB1 Antibodies (43) and CHRNB1 Kits (16) and many more products for this protein. A total of 69 CHRNB1 products are currently listed.
Synonyms:
Achr-2, ACHRB, Acrb, CHRNB, CHRNB1, CMS1D, CMS2A, RNACRB1, SCCMS
list all proteins Gene Name GeneID UniProt
CHRNB1 1140 P11230
Rat CHRNB1 CHRNB1 24261 P25109
CHRNB1 11443 P09690

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CHRNB1 Proteins (CHRNB1) by Origin

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Human Cholinergic Receptor, Nicotinic, beta 1 (Muscle) (CHRNB1) interaction partners

  1. This study reports on the presence of the CHRNB1 at the cellular level in human skeletal muscle and placenta and that mRNA expression mirrors that of protein within cell types.

  2. Association of the nicotinic acetylcholine receptor beta1 subunit (CHRNB1) and M1 muscarinic acetylcholine receptor (show CHRNA1 Proteins) (CHRM1 (show CHRM1 Proteins)) with vulnerability for nicotine dependence.

  3. No CHRNA1 (show CHRNA1 Proteins), CHRNB1, or CHRND (show CHRND Proteins) mutations were detected, but a homozygous RAPSN (show RAPSN Proteins) frameshift mutation, c.1177-1178delAA, was identified in a family with three children affected with lethal fetal akinesia sequence.

Mouse (Murine) Cholinergic Receptor, Nicotinic, beta 1 (Muscle) (CHRNB1) interaction partners

  1. Conformational changes involved in channel gating propagate from the binding-site to the channel in the ACh (show FGFR3 Proteins)-binding subunits and subsequently spread to the non-binding subunit.

  2. The metabolic stabilization of the AChR by agrin (show AGRN Proteins) or pervanadate was mediated specifically by phosphorylation of betaY390.

  3. Tyrosine phosphorylation of the acetylcholine receptor (AChR) beta-subunit (show POLG Proteins) is important in organizing AChRs and regulating synaptic differentiation.

  4. In V266M mutant the peak-current amplitude decreases along trains of nearly saturating ACh (show FGFR3 Proteins) pulses delivered at physiologically relevant frequencies, consistent with enhanced entry into desensitization in congenital myasthenic syndrome.

CHRNB1 Protein Profile

Protein Summary

The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome.

Alternative names and synonyms associated with CHRNB1

  • cholinergic receptor, nicotinic, beta 1 (muscle) (CHRNB1)
  • cholinergic receptor, nicotinic, beta 1 (muscle) (chrnb1)
  • acetylcholine receptor beta subunit (LOC386576)
  • cholinergic receptor, nicotinic, beta 1 (muscle) (Chrnb1)
  • cholinergic receptor, nicotinic, beta polypeptide 1 (muscle) (Chrnb1)
  • Achr-2 protein
  • ACHRB protein
  • Acrb protein
  • CHRNB protein
  • CHRNB1 protein
  • CMS1D protein
  • CMS2A protein
  • RNACRB1 protein
  • SCCMS protein

Protein level used designations for CHRNB1

nicotinic acetylcholine receptor beta 1 subunit , cholinergic receptor, nicotinic, beta 1 (muscle) , AChR beta1b , acetylcholine receptor subunit beta , acetylcholine receptor subunit beta 1 , nicotinic acetylcholine receptor subunit beta 1b , acetylcholine receptor, nicotinic, beta 1 (muscle) , cholinergic receptor, nicotinic, beta polypeptide 1 (muscle) , Acetylcholine receptor beta , cholinergic receptor nicotinic beta polypeptide 1 , AChR beta , acetylcholine receptor beta

GENE ID SPECIES
454461 Pan troglodytes
489473 Canis lupus familiaris
715509 Macaca mulatta
100006941 Danio rerio
386576 Gallus gallus
1140 Homo sapiens
24261 Rattus norvegicus
282179 Bos taurus
11443 Mus musculus
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