Browse our Glutamate Dehydrogenase 2 Proteins (GLUD2)

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Glutamate Dehydrogenase 2 Proteins (GLUD2)
On www.antibodies-online.com are 5 Glutamate Dehydrogenase 2 (GLUD2) Proteins from 4 different suppliers available. Additionally we are shipping Glutamate Dehydrogenase 2 Antibodies (63) and many more products for this protein. A total of 74 Glutamate Dehydrogenase 2 products are currently listed.
Synonyms:
EG545999, GDH2, Glud-2, GluD2, GLUDP1, glutamate dehydrogenase 2, Gm5902, T2I1.150, T2I1_150
list all proteins Gene Name GeneID UniProt
GLUD2 2747 P49448
Mouse GLUD2 GLUD2 104277  
Rat GLUD2 GLUD2 79220 Q63226

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Glutamate Dehydrogenase 2 Proteins (GLUD2) by Origin

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Human Glutamate Dehydrogenase 2 (GLUD2) interaction partners

  1. The expression of GLUD2 was identified in the cellular and subcellular compartments of numerous tissues.

  2. Notably, the introduction of GLUD2 did not affect glutamate (show GRIN1 Proteins) levels in mice, consistent with observations in the primates. Instead, the metabolic effects of GLUD2 center on the tricarboxylic acid cycle, suggesting that GLUD2 affects carbon flux during early brain development, possibly supporting lipid biosynthesis.

  3. Study of the expression of the GDH1 (show GLUD1 Proteins)/2 in human steroidogenic organs revealed that, while GDH2 was expressed specifically in steroid-synthesizing cells, GDH1 (show GLUD1 Proteins) was expressed both in the cells that produce steroids and in those that lack endocrine function.

  4. IDH1 (show IDH1 Proteins)(R132H) exhibits a growth-inhibitory effect that is abrogated in the presence of glutamate dehydrogenase 2 (GLUD2), a hominoid-specific enzyme purportedly optimized to facilitate glutamate (show GRIN1 Proteins) turnover in human forebrain.

  5. hGDH2 can operate efficiently in the relatively acidic environment that prevails in astrocytes following glutamate (show GRIN1 Proteins) uptake [review]

  6. [review] Whereas GDH2 in most mammals is encoded by a single functional GLUD1 gene expressed widely, humans have acquired through retroposition an X-linked GLUD2 gene that encodes a highly homologous isoenzyme GDH2 expressed in testis and brain.

  7. Human GDH1 (show GLUD1 Proteins) appears to act like bovine GDH1 (show GLUD1 Proteins), but human GDH2 does not show the same enhancement of branched chain alpha-keto acid dehydrogenase complex enzyme activities.

  8. GLUD2 glutamate (show GRIN1 Proteins) dehydrogenase is expressed in neural and testicular supporting cells

  9. identify the structural basis for allosteric differences of GlUD1 (show GLUD1 Proteins) and GLUD2

  10. These results suggest that the Ser443 residue plays an important role in the different thermal stability of human glutamate (show GRIN1 Proteins) dehydrogenase isozymes (hGDH1 and hGDH2).

Arabidopsis thaliana Glutamate Dehydrogenase 2 (GLUD2) interaction partners

  1. In leaves and stems of arabidopsis and tobacco, both the alpha- and beta-subunits of Glutamate (show GRIN2A Proteins) dehydrogenase are targeted to the mitochondria of the companion cells.

  2. Protein phosphorylation by serine/threonine protein kinases is the essential step required for signal transduction into nucleus resulting in the induction of glutamate dehydrogenase 2 expression.

Mouse (Murine) Glutamate Dehydrogenase 2 (GLUD2) interaction partners

  1. GluD2 signaling induces parallel fiber protrusions that form circular structures and encapsulated Purkinje cell spines.

  2. These findings indicate how GluD2 is activated and regulates functions at parallel fiber-Purkinje cell synapses--{REVIEW}

  3. the flap (show ALOX5AP Proteins) loop (Arg321-Trp339) in the NTD of GluD2 (GluD2-NTD) was identified as a crucial region for the binding to Cbln1 (show CBLN1 Proteins) and the induction of presynaptic differentiation.

  4. The results of this study suggest that GluD2 differently regulates parallel fiber synaptogenesis and cerebellar long-term depression through the extracellular N-terminal domain and the cytoplasmic C-terminal end, respectively.

Glutamate Dehydrogenase 2 (GLUD2) Protein Profile

Protein Summary

The protein encoded by this gene is localized to the mitochondrion and acts as a homohexamer to recycle glutamate during neurotransmission. The encoded enzyme catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate. This gene is intronless.

Alternative names and synonyms associated with Glutamate Dehydrogenase 2 (GLUD2)

  • glutamate dehydrogenase 2 (gdhA_2)
  • glutamate dehydrogenase 2 (GLUD2)
  • glutamate dehydrogenase 2 (GDH2)
  • glutamate dehydrogenase, pseudogene (Glud-ps)
  • glutamate receptor, ionotropic, delta 2 (Grid2)
  • EG545999 protein
  • GDH2 protein
  • Glud-2 protein
  • GluD2 protein
  • GLUDP1 protein
  • glutamate dehydrogenase 2 protein
  • Gm5902 protein
  • T2I1.150 protein
  • T2I1_150 protein

Protein level used designations for GLUD2

glutamate dehydrogenase 2 , GDH 2 , glutamate dehydrogenase 2, mitochondrial , glutamate dehydrogenase pseudogene 1 , gluR delta-2 subunit , glutamate receptor delta-2 subunit , glutamate receptor ionotropic, delta-2

GENE ID SPECIES
3702749 Natronomonas pharaonis DSM 2160
2747 Homo sapiens
830635 Arabidopsis thaliana
104277 Mus musculus
79220 Rattus norvegicus
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