Browse our GRID2 Proteins (GRID2)

Full name:
Glutamate Receptor, Ionotropic, delta 2 Proteins (GRID2)
On are 9 Glutamate Receptor, Ionotropic, delta 2 (GRID2) Proteins from 2 different suppliers available. Additionally we are shipping GRID2 Kits (26) and GRID2 Antibodies (20) and many more products for this protein. A total of 56 GRID2 products are currently listed.
B230104L07Rik, cpr, GluD2, glurd2, GluRdelta2, GRID2, ho, Lc, Lc, MMS10-AC, Ms10ac, nmf408, si:rp71-1l7.1, tpr
list all proteins Gene Name GeneID UniProt
GRID2 2895 O43424
GRID2 14804 Q61625
Rat GRID2 GRID2 79220 Q63226

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GRID2 Proteins (GRID2) by Origin

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More Proteins for GRID2 Interaction Partners

Zebrafish Glutamate Receptor, Ionotropic, delta 2 (GRID2) interaction partners

  1. These results suggest that the expression of zebrafish GluRdelta2 is selective for cerebellum-like neural wiring with large numbers of parallel fiber inputs.

Human Glutamate Receptor, Ionotropic, delta 2 (GRID2) interaction partners

  1. GRID2 gene can be a suppressor in TNF (show TNF Proteins)-induced neurodegeneration which may help to understand the main factors leading to autism.

  2. Glutamate (show GRIN1 Proteins) system genes including have been associated with disease risk in recent analyses from the Psychiatric Genomics Consortium.

  3. findings suggest a possible role of GRID2 in the susceptibility to develop mevalonate kinase (show MVK Proteins) deficiency. GRID2 gene associated with MKD: The rs1450500 SNP was differently distributed in patients with MKD with respect to those with recurrent fever.

  4. We demonstrated for the first time GRID2 expression and localization in human and murine retina, providing evidence for a novel functional role of GRID2 in the retina.

  5. GRID2 point mutations: cerebellar ataxia (show USP14 Proteins) is the core phenotype, but with variable severity ranging from very mild adult-onset to congenital-onset linked to both the heterozygous and homozygous state of the variant, and the position of the mutation.

  6. GluD2 (show GLUD2 Proteins) gating is triggered by type 1 metabotropic glutamate (show GRIN1 Proteins) receptors.

  7. GRID2 mutations are associated with a recessive syndrome causing cerebellar ataxia (show USP14 Proteins) and eye movement abnormalities.

  8. Tests for gene-environment interaction between these 33 genes and maternal smoking found evidence for interaction with two additional genes: GRID2 and ELAVL2 (show ELAVL2 Proteins) among European mothers

  9. Glutamate (show GRIN1 Proteins) receptor delta2 is involved in a common mechanism that restricts the number of synaptic AMPA (show GRIA3 Proteins) receptors at parallel fiber synapses in cerebellar Purkinje cells.

  10. Thus, phosphorylation of -2T and/or -1S of GluRdelta2 C-terminus by PKA may regulate the binding of GluRdelta2 to its scaffolding protein, Delphilin (show GRID2IP Proteins).

Mouse (Murine) Glutamate Receptor, Ionotropic, delta 2 (GRID2) interaction partners

  1. The GluD2 (show GLUD2 Proteins) mutation in the ho15J mice affects stable retention of the acquired conditioned bradycardia.

  2. Notably, the introduction of GLUD2 (show GLUD2 Proteins) did not affect glutamate (show GRIN1 Proteins) levels in mice, consistent with observations in the primates. Instead, the metabolic effects of GLUD2 (show GLUD2 Proteins) center on the tricarboxylic acid cycle, suggesting that GLUD2 (show GLUD2 Proteins) affects carbon flux during early brain development, possibly supporting lipid biosynthesis.

  3. This study showed that spontaneous Grid2 mutations causing cerebellar pathology are impaired in motor functions during the neonatal period.

  4. Established is a mouse line with an autosomal recessive gene mutation characterized by progressive ataxia (show USP14 Proteins) and significant cerebellar atrophy.

  5. GluD2 (show GLUD2 Proteins) works in concert with GluD1 (show GLUD1 Proteins) for the construction of cerebellar synaptic wiring through distinct neuronal and synaptic expressions.

  6. Climbing fiber signals in Glu2 receptor delta2 knock-out mice propagate across multiple microzones.

  7. GluD2 (show GLUD2 Proteins) deletion impairs presynaptic R-type voltage-gated Ca(2 (show CA2 Proteins)+) channels, resulting in decreased release of synaptic vesicles

  8. The results suggest that multiple PC death pathways are induced by the physical trauma of making organotypic slice cultures, naturally-occurring postnatal cell death, and the GluRdelta2 (Lc) mutation.

  9. CD95 (show FAS Proteins) and soluble CD95L (show FASL Proteins) contribute, via non-apoptotic signaling, to the inflammatory reaction initiated early in neuron death within the Grid2(Lc/+) cerebellum

  10. activity-dependent phosphorylation of serine 880 (S880) in GluA2 (show GRIA2 Proteins) AMPA (show GRIA3 Proteins) receptor subunit, which is an essential step for AMPA (show GRIA3 Proteins) receptor endocytosis during LTD induction, was impaired in GluD2 (show GLUD2 Proteins)-null cerebellum

GRID2 Protein Profile

Protein Summary

Human glutamate receptor delta-2 (GRID2) is a relatively new member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. GRID2 is a predicted 1,007 amino acid protein that shares 97% identity with the mouse homolog which is expressed selectively in cerebellar Purkinje cells. A point mutation in mouse GRID2, associated with the phenotype named 'lurcher', in the heterozygous state leads to ataxia resulting from selective, cell-autonomous apoptosis of cerebellar Purkinje cells during postnatal development. Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis. This strongly suggests a role for GRID2 in neuronal apoptotic death.

Alternative names and synonyms associated with GRID2

  • glutamate receptor, ionotropic, delta 2 (grid2)
  • glutamate receptor, ionotropic, delta 2 (GRID2)
  • glutamate receptor, ionotropic, delta 2 (Grid2)
  • B230104L07Rik protein
  • cpr protein
  • GluD2 protein
  • glurd2 protein
  • GluRdelta2 protein
  • GRID2 protein
  • ho protein
  • Lc protein
  • Lc protein
  • MMS10-AC protein
  • Ms10ac protein
  • nmf408 protein
  • si:rp71-1l7.1 protein
  • tpr protein

Protein level used designations for GRID2

gluR delta-2 subunit , glutamate receptor delta-2 subunit , glutamate receptor ionotropic, delta-2 , glutamate receptor, ionotropic, delta 2 , glutamate receptor delta-2 subunit-like , GluR-delta-2 , creeper , hotfoot , lurcher , minisatellite 10ac detected by probe MMS10

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