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Browse our GRIN1 (GRIN1) ELISA Kits

Full name:
Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 ELISA Kits (GRIN1)
On www.antibodies-online.com are 23 Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1) ELISA Kits from 10 different suppliers available. Additionally we are shipping GRIN1 Antibodies (257) and GRIN1 Proteins (10) and many more products for this protein. A total of 301 GRIN1 products are currently listed.
Synonyms:
4930447P04Rik, GB19253, GluN1, GluRdelta1, GluRzeta1, GRIN1, M100174, MRD8, Ndor, NMD-R1, NMDA1, Nmdar, NMDAR1, NR1, Rgsc174
list all ELISA KIts Gene Name GeneID UniProt
GRIN1 2902 Q05586
GRIN1 24408 P35439
GRIN1 14810 P35438

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More ELISA Kits for GRIN1 Interaction Partners

Human Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1) interaction partners

  1. De novo GRIN1 mutations are associated with severe intellectual disability with cortical visual impairment as well as oculomotor and movement disorders being discriminating phenotypic features. Loss of NMDA receptor function appears to be the underlying disease mechanism. The identification of both heterozygous and homozygous mutations blurs the borders of dominant and recessive inheritance of GRIN1-associated disorders.

  2. The differences in cortical NMDAR expression and post-synaptic density protein 95 (show DLG4 ELISA Kits) are present in psychiatric disorders and suicide completion and may contribute to different responses to ketamine.

  3. GRIN1 (rs4880213) was significantly associated with depression and disruptive behavior in adolescents.

  4. Knockdown of PKD1 (show PKD1 ELISA Kits) did not affect NMDAR internalization but prevented the phosphorylation and inhibition of remaining surface NMDARs and NMDAR-mediated synaptic functions.

  5. Study found GluN receptor subunit-specific changes in mixed subcortical ischemic vascular dementia(SIVD)/Alzheimer's disease(AD) (decreased GluN1) and SIVD (increased GluN2A (show GRIN2A ELISA Kits) and 2B), likely reflecting interaction of ischemic neurovascular and AD processes

  6. The results of this study suggested that GRIN1 mutations cause encephalopathy resulting in seizures and movement disorders.

  7. Genome-wide significant marker, SNP rs524991, and an association of seropositivity with influenza autoantibodies status, we provide genetic and environmental risk factors of NMDAR-autoantibodies formation

  8. Epigenetic changes in GRIN1, in combination with experiences of maltreatment, may confer risk for depression in children.

  9. Reduction in NR1 and NR2C (show GRIN2C ELISA Kits) in the DLPFC of people with schizophrenia may lead to altered NMDAR stoichiometry and provides compelling evidence for an endogenous NMDAR deficit in schizophrenia.

  10. Isolated GluN1/GluN3A (show GRIN3A ELISA Kits) receptors integrated into lipid bilayers responded to addition of either glycine or d-serine, but not glutamate, with a approximately 1 nm reduction in height of the extracellular domain

Xenopus laevis Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1) interaction partners

  1. Establishment of late-phase long-term potentiation (L-LTP (show SCP2 ELISA Kits)) in vivo requires NMDAR activation in the postsynaptic tectal cells within a critical time window after LTP (show SCP2 ELISA Kits) induction.

  2. PIP2 supports the open state of NMDA receptors via the adaptor protein alpha-actinin (show ACTN1 ELISA Kits). PIP2 and alpha-actinin (show ACTN1 ELISA Kits) act like a two-component hinge keeping the channel gate in its open state.

Mouse (Murine) Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1) interaction partners

  1. In diabetic mice, knockdown of NR1 using lentivirus carrying NR1-shRNA ameliorated the pathological features associated with diabetic kidney disease. NR1 knockdown decreased the cell shape remodelling, cell collapse, bovine serum albumin (show ALB ELISA Kits) permeability, and migration induced by high glucose.

  2. In a model of depressive disorder, the oxidation of NR1 by NOX1 (show NOX1 ELISA Kits)-derived reactive oxygen species was demonstrated in prefrontal cortex.

  3. the present study demonstrates that nNOS-derived NO signaling modulated by spinal Sig-1R activation increases Nox2 activity and concomitant ROS production, which leads to a ROS-induced increase in PKC-dependent pGluN1 expression in the spinal cord dorsal horn and the development of pain hypersensitivity

  4. NMDAR1 plays a pivotal role in hemin-induced NLRP3 (show NLRP3 ELISA Kits)-mediated inflammatory damage through synergistic activation.

  5. Nbea (show NBEA ELISA Kits) targets glutamate and GABA receptors to the synapse via distinct molecular pathways by interacting with specific effector proteins.

  6. Study demonstrated that NMDAR functions are regulated by ghrelin (show GHRL ELISA Kits) in a GHSR1a-dependent manner: NMDAR-mediated synaptic currents are increased as a result of GluN1 subunit phosphorylation in the hippocampal pyramidal neurons and synapses

  7. Lysosomal iron modulates NMDA receptor-mediated excitation via small GTPase (show RACGAP1 ELISA Kits), Dexras1 (show RASD1 ELISA Kits)

  8. Deletion of the gene encoding the essential NR1 subunit of the NMDA receptor (NMDAR), restricted to the CA1 (show CA1 ELISA Kits) region of the hippocampus results in abnormal fear response in mice.

  9. Heterozygous NR1 (+/-) mice with reduced glutamate function are more sensitive to the disruptive effects of social isolation.

  10. EphB2 (show EPHB2 ELISA Kits) prevents amyloid-beta-induced depletion of cell surface GluN1 requiring the PDZ (show INADL ELISA Kits)-binding motif of EphB2 (show EPHB2 ELISA Kits)

GRIN1 Antigen Profile

Antigen Summary

The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.

Alternative names and synonyms associated with GRIN1

  • glutamate receptor, ionotropic, N-methyl D-aspartate 1 (grin1) Elisa Kit
  • glutamate receptor, ionotropic, N-methyl D-aspartate 1 (GRIN1) Elisa Kit
  • NMDA receptor 1 (Nmdar1) Elisa Kit
  • glutamate receptor, ionotropic, N-methyl D-aspartate 1 (Grin1) Elisa Kit
  • glutamate receptor, ionotropic, NMDA1 (zeta 1) (Grin1) Elisa Kit
  • NADPH dependent diflavin oxidoreductase 1 (Ndor1) Elisa Kit
  • 4930447P04Rik Elisa Kit
  • GB19253 Elisa Kit
  • GluN1 Elisa Kit
  • GluRdelta1 Elisa Kit
  • GluRzeta1 Elisa Kit
  • GRIN1 Elisa Kit
  • M100174 Elisa Kit
  • MRD8 Elisa Kit
  • Ndor Elisa Kit
  • NMD-R1 Elisa Kit
  • NMDA1 Elisa Kit
  • Nmdar Elisa Kit
  • NMDAR1 Elisa Kit
  • NR1 Elisa Kit
  • Rgsc174 Elisa Kit

Protein level used designations for GRIN1

glutamate receptor, ionotropic, N-methyl D-aspartate 1 , NMDA-type glutamate receptor 1 , NMDA-type glutamate receptor subunit 1 , N-methyl-D-aspartate receptor 1 , glutamate [NMDA] receptor subunit zeta-1 , N-methyl-D-aspartate receptor channel, subunit zeta-1 , N-methyl-D-aspartate receptor subunit NR1 , NMD-R1 , glutamate [NMDA] receptor subunit zeta 1 , glutamate receptor ionotropic, NMDA 1 , N-methyl-D-aspartate glutamate receptor , NMDA R1 receptor C1 cassette , neurotransmitter receptor , Glutamate [NMDA] receptor subunit zeta-1 , glutamate receptor subunit zeta 1 , N-methyl-D-aspartate receptor , NMDA glutamate receptor , N-methyl-D-aspartate receptor type 1 , NADPH-dependent diflavin oxidoreductase 1

GENE ID SPECIES
780048 Xenopus (Silurana) tropicalis
100023485 Monodelphis domestica
406079 Apis mellifera
443281 Ovis aries
751779 Taeniopygia guttata
2902 Homo sapiens
24408 Rattus norvegicus
494007 Canis lupus familiaris
397953 Xenopus laevis
404296 Gallus gallus
14810 Mus musculus
78797 Mus musculus
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