Browse our Neuroligin 3 Proteins (NLGN3)

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Neuroligin 3 Proteins (NLGN3)
On are 13 Neuroligin 3 (NLGN3) Proteins from 7 different suppliers available. Additionally we are shipping Neuroligin 3 Antibodies (99) and Neuroligin 3 Kits (7) and many more products for this protein. A total of 126 Neuroligin 3 products are currently listed.
A230085M13Rik, CCE-L1, GB18290, HNL3, NL3, NLGN3, NV16744, Nv1604741
list all proteins Gene Name GeneID UniProt
NLGN3 54413 Q9NZ94
NLGN3 245537 Q8BYM5
Rat NLGN3 NLGN3 171297 Q62889

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Neuroligin 3 Proteins (NLGN3) by Origin

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Top referenced Neuroligin 3 Proteins

  1. Human NLGN3 Protein expressed in Human Cells - ABIN2004032 : Irie, Hata, Takeuchi, Ichtchenko, Toyoda, Hirao, Takai, Rosahl, Südhof: Binding of neuroligins to PSD-95. in Science (New York, N.Y.) 1997 (PubMed)
    Show all 2 references for 2004032

  2. Human NLGN3 Protein expressed in HEK-293 Cells - ABIN2181537 : Graf, Zhang, Jin, Linhoff, Craig: Neurexins induce differentiation of GABA and glutamate postsynaptic specializations via neuroligins. in Cell 2004 (PubMed)
    Show all 2 references for 2181537

  3. Human NLGN3 Protein expressed in HEK-293 Cells - ABIN2727167 : Venkatesh, Johung, Caretti, Noll, Tang, Nagaraja, Gibson, Mount, Polepalli, Mitra, Woo, Malenka, Vogel, Bredel, Mallick, Monje: Neuronal Activity Promotes Glioma Growth through Neuroligin-3 Secretion. in Cell 2015 (PubMed)

More Proteins for Neuroligin 3 Interaction Partners

Human Neuroligin 3 (NLGN3) interaction partners

  1. No statistically significant haplotypes have been found associated to autism in the NLGN3 after logistic regression and permutation analysis.

  2. The synaptic protein neuroligin-3 (NLGN3) was identified as the leading candidate mitogen, and soluble NLGN3 was sufficient and necessary to promote robust high-grade glioma cell proliferation.

  3. Our data provided a further evidence for the involvement of NLGN3 and NLGN4X (show NLGN4X Proteins) gene in the pathogenesis of autism in Chinese population.

  4. The present study explores, for the first time, the contribution of NLGN3 and NLGN4X (show NLGN4X Proteins) genetic variants in Greek patients with autistic disorder.

  5. Lack of association between NLGN3, NLGN4, SHANK2 and SHANK3 gene variants and autism spectrum disorder in a Chinese population.

  6. Neuroligins are adhesion proteins that bind to beta-neurexin (show NRXN1 Proteins) to form functional synapses.

  7. Data from studies using cross-linking reagents suggest that neuroligins form dimers, including homodimers and, most notably, neuroligin 1 (show NLGN1 Proteins)/3 heteromers; autism-associated neuroligin mutant (neuroligin 3 R471C) forms heterodimers with neuroligin 1 (show NLGN1 Proteins).

  8. study provides initial evidence that a common variant in NLGN3 gene may play a role in the etiology of ASDs among affected males in Chinese Han population.

  9. further characterization of the R451C mutation in NLGN3;role in protein folding

  10. report mutations in two X-linked genes encoding neuroligins NLGN3 and NLGN4 (show NLGN4X Proteins) in siblings with autism-spectrum disorders

Mouse (Murine) Neuroligin 3 (NLGN3) interaction partners

  1. The NL3 deletion-mutant mouse was a dramatic reduction of the number of GABAAalpha2-subunit containing GABAA (show GABRg1 Proteins) receptor clusters at the retinal inner plexiform layer.

  2. that neuroligin-3 specifies the properties of excitatory synapses on parvalbumin (show PVALB Proteins)-containing interneurons by a retrograde trans-synaptic mechanism and suggest a molecular pathway whereby neuroligin-3 mutations contribute to neuropsychiatric disorders

  3. Study shows altered mating behavior in the Neuroligin-3(R451C mutation) mouse and has provides new insights into the aggressive phenotype in this model.

  4. Nlgn3 and Nrxn1 (show NRXN1 Proteins) are differentially expressed in cerebral cortex and hippocampus which might be responsible for alternations in synaptic plasticity during aging.

  5. These findings suggest that structural changes in the brain of NL-3 mice are induced by the mutation in the NL-3 gene

  6. Thus our data suggest that perinatal exposure to BPA (show DST Proteins) impairs spatial memory through upregulation of expression of synaptic proteins Nrxn1 (show NRXN1 Proteins) and Nlgn3 and increased dendritic spine density in cerebral cortex and hippocampus of postnatal male mice.

  7. Therefore, we sought to replicate our findings in the neuroligin-3 R451C point mutant knock-in mouse model (NL3R451C) in a different genetic background.

  8. We used MRI (show C7ORF49 PLURAL_@35191@) to image three genetic mouse models with single mutations implicated in autism: Neuroligin-3 R451C knock-in, Methyl-CpG binding protein-2 (MECP2 (show MECP2 PLURAL_@35191@)) 308-truncation and integrin beta3 homozygous knockout.

  9. Results indicate that autism spectrum disorders (ASD (show GUSB Proteins))-associated NL3 mutations commonly disrupt striatal circuits in a subregion-, cell-type-, and synapse-specific fashion and suggest that this disruption may shape repetitive and stereotypic behaviors associated with ASD (show GUSB Proteins).

  10. Neuroligin-3 R704C-mutant induced neurons exhibit a large and selective decrease in AMPA (show GRIA3 Proteins)-type glutamate (show GRIN1 Proteins) receptor-mediated synaptic transmission without changes in NMDA-type glutamate (show GRIN1 Proteins) receptor- or in GABAA (show GABRg1 Proteins) receptor-mediated synaptic transmission.

Neuroligin 3 (NLGN3) Protein Profile

Protein Summary

This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. Mutations in this gene may be associated with autism and Asperger syndrome. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Alternative names and synonyms associated with Neuroligin 3 (NLGN3)

  • neuroligin 3 (Nlgn3)
  • neuroligin 3 (nlgn3)
  • neuroligin 3 (NLGN3)
  • neuroligin 3 (NLG-3)
  • A230085M13Rik protein
  • CCE-L1 protein
  • GB18290 protein
  • HNL3 protein
  • NL3 protein
  • NLGN3 protein
  • NV16744 protein
  • Nv1604741 protein

Protein level used designations for Neuroligin 3 Proteins (NLGN3)

neuroligin 3 , neuroligin-3 , neuroligin 3 isoform A1A2 , carboxylesterase clade L, member 3 , gliotactin homolog , neuroligin 3 protein , Neuroligin-3

409003 Apis mellifera
447240 Xenopus laevis
473660 Pan troglodytes
511251 Bos taurus
659852 Tribolium castaneum
770104 Gallus gallus
100121155 Nasonia vitripennis
100329188 Xenopus (Silurana) tropicalis
54413 Homo sapiens
491947 Canis lupus familiaris
245537 Mus musculus
171297 Rattus norvegicus
574216 Macaca mulatta
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