Browse our CADPS Proteins (CADPS)

Full name:
Ca++-Dependent Secretion Activator Proteins (CADPS)
On are 5 Ca++-Dependent Secretion Activator (CADPS) Proteins from 3 different suppliers available. Additionally we are shipping CADPS Antibodies (26) and CADPS Kits (4) and many more products for this protein. A total of 36 CADPS products are currently listed.
AU067781, CADPS1, caps, CAPS-1, caps1, Caps2, mKIAA1121, si:busm1-6a2.7, si:dz6a2.7
list all proteins Gene Name GeneID UniProt
Rat CADPS CADPS 26989 Q62717
CADPS 27062 Q80TJ1

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CADPS Proteins (CADPS) by Origin

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More Proteins for CADPS Interaction Partners

Human Ca++-Dependent Secretion Activator (CADPS) interaction partners

  1. the p (show CAPS Proteins)referential binding of CAPS1 to open syntaxin-1 can (show STX1A Proteins) contribute to the stabilization of the open state of syntaxin-1 during its transition from "closed" state to the SNA (show STX1A Proteins)RE complex formation.

  2. Increased level of CADPS protein, human in Schizophrenic patients

  3. Loss of CADPS is associated with central nervous system primitive neuroectodermal tumor.

  4. Regulation of dense core vesicle release from PC12 cells by interaction between the D2 dopamine receptor (show DRD2 Proteins) and calcium-dependent activator protein for secretion (CAPS (show CAPS Proteins)).

Mouse (Murine) Ca++-Dependent Secretion Activator (CADPS) interaction partners

  1. CAPS1 (show CAPS Proteins) protein plays an important role during protein release from secretory granules in hippocampal neurons. The cytosolic protein CAPS1 (show CAPS Proteins) regulates several stages of secretory granule processing.

  2. identified a specific interaction of CAPS1 (show CAPS Proteins) with septin (show SEPT6 Proteins) family proteins; demonstrated that the C-terminal region of the CAPS1 (show CAPS Proteins) protein binds to part of the deduced GTP-binding (show RND2 Proteins) domain of septin (show SEPT6 Proteins) proteins.

  3. data indicate that CAPS-1 promotes fusion competence of immobile (tethered) DCVs in presynaptic terminals and that CAPS-1 localization to DCVs is probably not essential for this role

  4. Naturally occurring splice variants of CAPS2 (show CADPS2 Proteins) in CAPS1/CAPS2-deficient cells were studied and found that CAPS2 (show CADPS2 Proteins) primes vesicles independently of its MUN domain.

  5. Loss of CAPS1 (show CAPS Proteins) disrupts the trans-Golgi network-dense-core vesicle pathway.

  6. CAPS1 (show CAPS Proteins) binds to the full-length of cytoplasmic syntaxin-1 (show STX1A Proteins) with preference to its "open" conformation, whereas Munc13-1 binds to the first 80 N-terminal residues of syntaxin-1 (show STX1A Proteins).

  7. CAPS (show CAPS Proteins) family proteins exert dual roles in DCV trafficking, mediating trafficking at both the secretion site for exocytosis and at the Golgi complex for biogenesis

  8. a functional role for CAPS1 (show CAPS Proteins) in regulating DCV trafficking in the trans-Golgi network; this activity occurs via protein-protein interaction with ARF4 (show ARF4 Proteins)/ARF5 (show ARF5 Proteins) in a GDP-dependent manner.

  9. CAPS1 (show CAPS Proteins) has a role in constitutive and regulated exocytosis but not in loading of transmitters into dense core vesicles

  10. Data demonstrate that CAPS-1 and -2 generate and maintain a highly fusion competent synaptic vesicle pool that supports phasic Ca(2 (show CA2 Proteins)+) triggered release of transmitters.

CADPS Protein Profile

Protein Summary

This gene encodes a novel neural/endocrine-specific cytosolic and peripheral membrane protein required for the Ca2+-regulated exocytosis of secretory vesicles. The protein acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Alternative splicing has been observed at this locus and three variants, encoding distinct isoforms, are described.

Alternative names and synonyms associated with CADPS

  • Ca2+-dependent activator protein for secretion (cadps)
  • Ca++-dependent secretion activator (CADPS)
  • Ca++-dependent secretion activator (Cadps)
  • Ca++-dependent secretion activator (cadps)
  • Ca2+-dependent secretion activator (Cadps)
  • AU067781 protein
  • CADPS1 protein
  • caps protein
  • CAPS-1 protein
  • caps1 protein
  • Caps2 protein
  • mKIAA1121 protein
  • si:busm1-6a2.7 protein
  • si:dz6a2.7 protein

Protein level used designations for CADPS

Ca2+-dependent activator protein for secretion , Ca2+ dependent activator , Ca++-dependent secretion activator , calcium-dependent secretion activator 1-like , CAPS-1 , Ca2+-dependent secretion activator , Ca2+-regulated cytoskeletal protein , calcium-dependent activator protein for secretion 1 , calcium-dependent secretion activator 1 , Ca2+-dependent activator protein , Ca<2+-dependent activator protein for secretion , rCAPS , Ca<2+>dependent activator protein for secretion

368400 Danio rerio
100010948 Monodelphis domestica
100228459 Taeniopygia guttata
100408344 Callithrix jacchus
100454399 Pongo abelii
100471007 Ailuropoda melanoleuca
100518990 Sus scrofa
100583095 Nomascus leucogenys
8618 Homo sapiens
26989 Rattus norvegicus
444685 Xenopus laevis
27062 Mus musculus
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