Browse our Septin 5 Proteins (SEPT5)

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Septin 5 Proteins (SEPT5)
On are 11 Septin 5 (SEPT5) Proteins from 8 different suppliers available. Additionally we are shipping Septin 5 Antibodies (68) and Septin 5 Kits (13) and many more products for this protein. A total of 98 Septin 5 products are currently listed.
5-Sep, CDCREL, CDCREL-1, CDCrel-1A, CDCREL1, fj37h04, H5, HCDCREL-1, PNUTL1, SEPT5, wu:fj37h04, zgc:73218
list all proteins Gene Name GeneID UniProt
SEPT5 18951 Q9Z2Q6
SEPT5 116728 Q9JJM9
SEPT5 5413 Q99719

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Septin 5 Proteins (SEPT5) by Origin

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Top referenced Septin 5 Proteins

  1. Human SEPT5 Protein expressed in Escherichia coli (E. coli) - ABIN667493 : Bläser, Jersch, Hainmann, Wunderle, Zgaga-Griesz, Busse, Zieger: Human septin-septin interaction: CDCrel-1 partners with KIAA0202. in FEBS letters 2002 (PubMed)
    Show all 2 references for 667493

More Proteins for Septin 5 Interaction Partners

Mouse (Murine) Septin 5 (SEPT5) interaction partners

  1. Congenic knockout mice and mice overexpressing Sept5 in the hippocampus or amygdala were indistinguishable from control mice in novelty and olfactory responses, anxiety or motor activity

  2. Report SEPT4 (show SEPT4 Proteins)/5/7 expression in mouse cochlea and roles in auditory function.

  3. The result of this study suggested that Septin 5 is a core molecular substrate that differentiates distinct release modalities at the central synapse.

  4. Here, we showed existence of two Sept5 isoforms in the mouse and studied their tissue and developmental expressions that would be helpful for exploring isoform specific function.

  5. a role for CDCrel-1 in platelet secretion and aggregation.

  6. Transgenic mice expressing dominant negative parkin (show PARK2 Proteins) mutant accumulated moderate levels of Septin 5 in substantia nigra-dopaminerergic neurons. A threshold level of Septin 5 is required for dopaminergic cell loss.

  7. the interaction of Sept5 with syntaxin-1 (show STX1A Proteins) is regulated by the phosphorylation of Sept5_v1 at Ser17 by Cdk5 (show CDK5 Proteins)-p35 (show CDK5R1 Proteins)

  8. SEPT3 (show SEPT3 Proteins) and SEPT5 are dispensable for neuronal development as well as for synaptic vesicle fusion and recycling.

  9. Sept5 deficiency exerts pleiotropic effects on a select set of affective behaviors and cognitive processes.

Human Septin 5 (SEPT5) interaction partners

  1. CDCrel-1 overexpression exerts dopamine-dependent neurotoxicity and may contribute to the development of autosomal-recessive juvenile parkinsonism

  2. We studied the assembly of three human septins, SEPT4 (show SEPT4 Proteins), SEPT5 and SEPT8 (show SEPT8 Proteins), with each other (heterotypic) and with themselves (homotypic) using a yeast two-hybrid system.

  3. the high expression levels of PNUTL1 in human pancreatic endocrine cells that suggests a similar role of this protein in islet cells to that demonstrated in neuronal tissues, and warrants further functional studies of this protein.

  4. Our finding suggests a role for members of the septin (show SEPT6 Proteins) family in the development of proliferative retinal membranes.

  5. HSP70 (show HSP70 Proteins) and constitutively active HSF1 (show HSF1 Proteins) mediate protection against CDCrel-1-mediated toxicity

Septin 5 (SEPT5) Protein Profile

Protein Summary

This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB\; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Alternative names and synonyms associated with Septin 5 (SEPT5)

  • septin 5a (sept5a)
  • septin 5 (Sep-05)
  • septin 5 (SEPT5)
  • septin 5 (sept5)
  • septin 5 (Sept5)
  • 5-Sep protein
  • CDCREL protein
  • CDCREL-1 protein
  • CDCrel-1A protein
  • CDCREL1 protein
  • fj37h04 protein
  • H5 protein
  • HCDCREL-1 protein
  • PNUTL1 protein
  • SEPT5 protein
  • wu:fj37h04 protein
  • zgc:73218 protein

Protein level used designations for Septin 5 Proteins (SEPT5)

septin 5 , septin-5-like , cell division control related protein 1 , cell division control-related protein 1 , peanut-like 1 homolog , peanut-like protein 1 , septin-5 , CDCrel-1 , peanut-like 1 , platelet glycoprotein Ib beta chain

335925 Danio rerio
416778 Gallus gallus
458652 Pan troglodytes
712041 Macaca mulatta
100125069 Xenopus (Silurana) tropicalis
100468420 Ailuropoda melanoleuca
100544775 Meleagris gallopavo
18951 Mus musculus
116728 Rattus norvegicus
5413 Homo sapiens
615408 Bos taurus
486419 Canis lupus familiaris
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