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Browse our CD3D Proteins (CD3D)

Full name:
CD3d Molecule, delta (CD3-TCR Complex) Proteins (CD3D)
On are 29 CD3d Molecule, delta (CD3-TCR Complex) (CD3D) Proteins from 7 different suppliers available. Additionally we are shipping CD3D Antibodies (88) and CD3D Kits (6) and many more products for this protein. A total of 138 CD3D products are currently listed.
list all proteins Gene Name GeneID UniProt
CD3D 12500 P04235
CD3D 25710 P19377
CD3D 915 P04234

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CD3D Proteins (CD3D) by Origin

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Top referenced CD3D Proteins

  1. Human CD3D Protein expressed in Human Cells - ABIN2003686 : Arnett, Harrison, Wiley: Crystal structure of a human CD3-epsilon/delta dimer in complex with a UCHT1 single-chain antibody fragment. in Proceedings of the National Academy of Sciences of the United States of America 2004 (PubMed)
    Show all 2 references for ABIN2003686

  2. Cynomolgus CD3D Protein expressed in Human Cells - ABIN2009766 : Kjer-Nielsen, Dunstone, Kostenko, Ely, Beddoe, Mifsud, Purcell, Brooks, McCluskey, Rossjohn: Crystal structure of the human T cell receptor CD3 epsilon gamma heterodimer complexed to the therapeutic mAb OKT3. in Proceedings of the National Academy of Sciences of the United States of America 2004 (PubMed)
    Show all 2 references for ABIN2009766

  3. Human CD3D Protein expressed in HEK-293 Cells - ABIN2180772 : Gil, Busto, Garcillán, Chean, García-Rodríguez, Díaz-Alderete, Navarro, Reiné, Mencía, Gurbindo, Beléndez, Gordillo, Duchniewicz, Höhne, García-Sánchez, Fernández-Cruz, López-Granados, Schamel et al.: A leaky mutation in CD3D differentially affects ?? and ?? T cells and leads to a T??-T??+B+NK+ human SCID. ... in The Journal of clinical investigation 2011 (PubMed)

More Proteins for CD3D Interaction Partners

Mouse (Murine) CD3d Molecule, delta (CD3-TCR Complex) (CD3D) interaction partners

  1. CD3 (show CD3E Proteins)/CD28 (show CD28 Proteins)-inducible MNSFbeta (show FAU Proteins)-Bcl-G complex may be involved in the regulation of T cell function and survival.

  2. Polymorphisms of the CD3delta ectodomain exist in mice,some of which lead to amino acid substitutions which cause structural changes and affect anti-CD3 (show CD3E Proteins) antibody binding.

  3. mouse CD3delta has a T-cell specific expression pattern

  4. there is one molecule each of CD3delta and CD3gamma in the surface TCR/CD3 (show CD3E Proteins) complex

  5. A human CD3 (show CD3E Proteins) transgene that encodes full length CD3delta and a truncated but functional form of CD3epsilon (show CD3E Proteins) restored the defective preTCR function in not only CD3epsilon (show CD3E Proteins)- but CD3gamma- and CD3gammadelta-deficient mice as well.

  6. CD3delta and CD3gamma play a different role in humans and mice in pre-TCR and TCR function during alphabeta T-cell development

  7. CD3delta transgene rescues gammadelta T cell development in mice lacking both mouse CD3delta and CD3gamma.

Human CD3d Molecule, delta (CD3-TCR Complex) (CD3D) interaction partners

  1. A FOXP3 (show FOXP3 Proteins)(+)CD3 (show CD3 Proteins)(+)CD56 (show NCAM1 Proteins)(+)-expressed T-cell population with immunosuppressive function and reduced patient survival has been identified in cancer tissues of human hepatocellular carcinoma.

  2. The docking site for CD3 (show CD3 Proteins) subunits on the T Cell receptor beta chain has been identified by solution NMR.

  3. analysis of the molecular organization of the TCR-CD3 (show CD3 Proteins) complex

  4. Two cases of SCID (show PRKDC Proteins) with CD3delta gene mutation in Mexican Mennonite infants are described.

  5. The surface TCR expression of primary alphabeta and gammadelta T cells from healthy donors carrying a single null or leaky mutation in CD3G (gamma+/-) or CD3D (delta+/-, delta+/leaky) with that of normal controls, were compared.

  6. Altered expression of the TCR signaling related genes CD3 (show CD3 Proteins) and FcepsilonRIgamma in patients with aplastic anemia.

  7. A transgenic T cell receptor gammadelta-low expressing subset of T cells accumulates in mouse ear keratinocytes after IL-23 (show IL23A Proteins) injections.

  8. report 2 unrelated cases of SCID (show PRKDC Proteins) with a selective block in alphabeta but not in gammadelta T cell development, associated with a new splicing mutation in the CD3D gene

  9. Data show that the expression pattern of the four CD3 (show CD3 Proteins) chains was epsilon>zeta>delta>gamma in peripheral blood mononuclear cells from MM, while a gamma>epsilon>zeta>delta expression pattern was found in healthy controls.

  10. A combination of trastuzumab antibody and phosphoantigen-stimulated gammadelta T-lymphocytes increases the efficacy of trastuzumab alone against HER-2 (show ERBB2 Proteins)-positive breast carcinoma cell lines in vivo and mammary carcinoma xenografts in mice.

Pig (Porcine) CD3d Molecule, delta (CD3-TCR Complex) (CD3D) interaction partners

  1. In cystic teratomas of the ovary, CD1 (show CD1A Proteins)-positive Langerhans cells appeared to cross the basal membrane and penetrate the subepidermal tissue, and they were associated there with T-cell line lymphocytes (CD3 (show CD3 Proteins) positive).

CD3D Protein Profile

Protein Summary

The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.

Alternative names and synonyms associated with CD3D

  • CD3d molecule, delta (CD3-TCR complex) (CD3D)
  • CD3 antigen, delta polypeptide (Cd3d)
  • CD3 molecule, delta (Cd3d)
  • CD3-DELTA protein
  • T3D protein

Protein level used designations for CD3D

CD3d molecule, delta (CD3-TCR complex) , T-cell receptor T3 delta chain , T-cell surface glycoprotein CD3 delta chain , CD3 antigen delta polypeptide , CD3 molecule delta polypeptide , CD3 antigen, delta subunit , CD3 delta , CD3d antigen, delta polypeptide (TiT3 complex) , OKT3, delta chain , antigen CD3D, delta polypeptide (TiT3 complex) , CD3 antigen delta chain , CD3 antigen, delta polypeptide , TcR CD3 delta-chain , CD3 delta chain

451584 Pan troglodytes
12500 Mus musculus
25710 Rattus norvegicus
915 Homo sapiens
281053 Bos taurus
396661 Sus scrofa
443397 Ovis aries
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