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Mouse (Murine) CREB1 ELISA Kit - ABIN832415
Arora, Bhowmik, Khanam, Vohora: Oxcarbazepine and fluoxetine protect against mouse models of obsessive compulsive disorder through modulation of cortical serotonin and CREB pathway. in Behavioural brain research 2013
CREB is positively regulated by PKA and calcium-sensitive calcineurin and negatively by PKC.
The sequence of the CREB gene contains a 88 bp 5 (show HSPD1 ELISA Kits)' UTR (show UTS2R ELISA Kits), a 783 bp open reading frame encoding 261 amino acids and a 348 bp 3 (show BST1 ELISA Kits)' UTR (show UTS2R ELISA Kits).
Data indicate increasing expression for CREB, ATF1 (show AFT1 ELISA Kits), and ATF3 (show ATF3 ELISA Kits) during gastrulation.
Inhibition of CaN attenuated the hTau-induced CREB dephosphorylation with improved synapse and memory functions.
Via blocking the hypoxia-mediated reduction in CREB phosphorylation.
The study adds evidence that CREB, a tumor oncogene (show RAB1A ELISA Kits), promotes renal cell carcinoma proliferation. It probably achieves this by increasing SKA2 (show FAM33A ELISA Kits) expression
cigarette smoke extracts activate the PKA, CREB, and IL-13Ralpha2 axis in lung endothelial cells.
This study showed that the induction level of IL-32 (show IL32 ELISA Kits) was increased in chronic rhinosinusitis with nasal polyps compared to normal nasal mucosa and that LPS (show IRF6 ELISA Kits)-induced IL-32 (show IL32 ELISA Kits) expression in nasal polyp-derived fibroblasts was regulated via the TLR4 (show TLR4 ELISA Kits)/JNK (show MAPK8 ELISA Kits)/AKT (show AKT1 ELISA Kits)/CREB signaling pathway.
Studies indicate that the small molecule ICG-001 selectively blocks the cAMP response element-binding (CREB) protein (CBP (show CREBBP ELISA Kits))/beta-catenin (show CTNNB1 ELISA Kits) or gamma-catenin (show JUP ELISA Kits) interaction.
Study indicates that BPA (show DST ELISA Kits) increases phosphorylated CREB in MCF-7 Cells as well as it binding to SOX2 (show SOX2 ELISA Kits) enhancer.
study concludes that miR (show MLXIP ELISA Kits)-132 regulated SIRT1 (show SIRT1 ELISA Kits)/CREB/ABCG2 (show ABCG2 ELISA Kits) signaling pathway contributing to the cisplatin resistance and might serve as a novel therapeutic target against gastric cancer
Leptin (show LEP ELISA Kits) also significantly increased cAMP levels, cAMP response element (CRE) activation, and CREB phosphorylation.
these data show the existence of functional CREB and C/EBP (show CEBPA ELISA Kits) binding sites in the human RIC8B gene promoter, a particular distribution of these sites and demonstrate a relevant role of CREB in stimulating transcriptional activity of this gene.
LH induces MAPK3 (show MAPK3 ELISA Kits)/1 and Akt (show AKT1 ELISA Kits) activation, both of which are required for the CREB-promoted expression of EGF (show EGF ELISA Kits)-like factors in granulosa cells.
However, the mechanism that induces release of IL-6 (show IL6 ELISA Kits) from skeletal muscle cells remains unknown. Here we show that heat increases IL-6 (show IL6 ELISA Kits) in skeletal muscle cells through the transient receptor potential vannilloid 1, PKC (show PKC ELISA Kits), and cAMP response element-binding protein (show CREB ELISA Kits) signal transduction pathway.
NFIL3 (show NFIL3 ELISA Kits) functions as an important regulator of glucose homeostasis in the liver by limiting CREB-mediated hepatic gluconeogenesis
EGCG significantly ameliorated insulin (show INS ELISA Kits) resistance and cognitive disorder by up-regulating the insulin receptor substrate-1 (IRS-1 (show IRS1 ELISA Kits))/AKT (show AKT1 ELISA Kits) and ERK (show EPHB2 ELISA Kits)/cAMP response element binding protein (CREB (show CREB ELISA Kits))/brain-derived neurotrophic factor (BDNF (show BDNF ELISA Kits)) signaling pathways.
Ca(2 (show CA2 ELISA Kits)+) signaling pathway increases Nr4a1 (show NR4A1 ELISA Kits) expression in MA-10 Leydig cells, at least in part, by enhancing the recruitment of coactivator most likely through the MEF2 (show MEF2C ELISA Kits), AP1 (show JUN ELISA Kits), and CREB transcription factors thus demonstrating an important interplay between the Ca(2 (show CA2 ELISA Kits)+) and cAMP pathways in regulating Nr4a1 (show NR4A1 ELISA Kits) expression.
PGE2 serves as a central regulator of the Ren (show REN1 ELISA Kits)-1c gene in the principal cells of the kidney collecting ducts via the PKC (show PKC ELISA Kits)/cAMP/CREB pathway.
study revealed the involvement of CREB in B-1a cells, which was upregulated to increase the production of IL-10 (show IL10 ELISA Kits) for attenuating inflammation and organ injury, and finally improving survival during sepsis
In conclusion, glucocorticoid couples mGR (show GRHL1 ELISA Kits) with Galphas (show GNAS ELISA Kits) and triggers cAMP-PKA-CREB axis dependent on the lipid raft to stimulate BACE1 (show BACE ELISA Kits) upregulation and Abeta (show APP ELISA Kits) generation.SIGNIFICANCE STATEMENT Patients with Alzheimer's disease (AD) have been growing sharply and stress is considered as the major environment factor of AD.
CREB was found to bind to GSK3beta (show GSK3b ELISA Kits) promoter and essential for cAMP-mediated regulation of GSK3beta (show GSK3b ELISA Kits).
The NR2B (show GRIN2B ELISA Kits)-CREB-miR212/132-CRTC1 (show CRTC1 ELISA Kits)-CREB signal network plays an important role in the regulation of pain.
The expression of porcine Prdx6 (show PRDX6 ELISA Kits) gene is up-regulated by C/EBPbeta (show CEBPB ELISA Kits) and CREB.
Results suggest that cerebral hypoxia results in differential regulation of CREB protein-mediated expression of proapoptotic and antiapoptotic proteins in the cerebral cortex of newborn piglets.
Data indicate that Ser738/742-to-glutamate (show GRIN2A ELISA Kits) protein kinase D (show PRKD1 ELISA Kits) mutant increased AngII-induced CREB protein and activating transcription factor 2 (show ATF2 ELISA Kits) phosphorylation, and phospho-CREB binding to the steroidogenic acute regulatory protein (show STAR ELISA Kits) promoter.
SUMO-1 (show SUMO1 ELISA Kits) has a role in modifying cAMP-response element-binding protein CREB (show CREB ELISA Kits) in prolonged hypoxia.
dsRNA as well as other agonists of endothelial cells elicit signaling mechanisms that include in part CREB phosphorylation mediated by calcium-independent phospholipase A2 (show LYPLA1 ELISA Kits)
the p38-MAPK (show MAPK14 ELISA Kits)/CREB pathway plays a critical role in TNFalpha (show TNF ELISA Kits)-induced VCAM-1 (show VCAM1 ELISA Kits) expression
We found several conserved cis elements in the frog CRF genes including a cAMP response element (CRE), activator protein 1 binding sites, and glucocorticoid response elements
p38 MAPK (show MAPK14 ELISA Kits) and CREB function along the dorsal-ventral axis in mesoderm patterning. The phosphorylated form of CREB (S133) is distributed in a gradient along the dorsal-ventral mesoderm axis and the p38 MAPK (show MAPK14 ELISA Kits) pathway mediates the phosphorylation of CREB.
modulating CREB activity during early zebrafish development caused significant defects in neural proliferation, midbrain-hindbrain organization and body patterning
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
cAMP responsive element binding protein 1
, cAMP responsive element binding protein
, cyclic AMP-responsive element-binding protein 1
, active transcription factor CREB
, cAMP-response element-binding protein-1
, cAMP-responsive element-binding protein 1
, transactivator protein
, Y protein
, cAMP response element binding protein 1
, cAMP response element-binding protein
, cyclic AMP-responsive element binding protein, delta
, cyclic AMP-responsive DNA-binding protein