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Browse our Mu Opioid Receptor 1 Proteins (OPRM1)

Full name:
Opioid Receptor, mu 1 Proteins (OPRM1)
On www.antibodies-online.com are 6 Opioid Receptor, mu 1 (OPRM1) Proteins from 3 different suppliers available. Additionally we are shipping Mu Opioid Receptor 1 Antibodies (107) and Mu Opioid Receptor 1 Kits (12) and many more products for this protein. A total of 137 Mu Opioid Receptor 1 products are currently listed.
Synonyms:
6430411K18Rik, LMOR, M-OR-1, Mar, Mart1, MOP, MOP-R, mor, MOR-1, MOR-1O, MOR1, MORA, muOR, OPRM, OPRM1, Oprrm1, or2, Peg11, ZFOR2
list all proteins Gene Name GeneID UniProt
Rat OPRM1 OPRM1 81829 P04636
OPRM1 4988 P35372
OPRM1 18390 P42866

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Mu Opioid Receptor 1 Proteins (OPRM1) by Origin

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Top referenced Mu Opioid Receptor 1 Proteins

  1. Human Mu Opioid Receptor 1 Protein expressed in Wheat germ - ABIN1313419 : Perlikowska, Gach, Fichna, Toth, Walkowiak, do-Rego, Janecka: Biological activity of endomorphin and [Dmt1]endomorphin analogs with six-membered proline surrogates in position 2. in Bioorganic & medicinal chemistry 2009 (PubMed)

More Proteins for Mu Opioid Receptor 1 Interaction Partners

Zebrafish Opioid Receptor, mu 1 (OPRM1) interaction partners

  1. demonstrate that zfMOR exhibits a pharmacological profile similar to that of the mammalian MOR.

Human Opioid Receptor, mu 1 (OPRM1) interaction partners

  1. This study demonstrated that brain regions particularly related to the somatosensory component of pain processing are modulated by variations in OPRM1.

  2. siRNA-loaded RVG exosomes significantly reduced MOR mRNA and protein levels. Surprisingly, MOR siRNA delivered by the RVG exosomes strongly inhibited morphine relapse via the down-regulation of MOR expression

  3. No association has been found between the OPRM1 A118G SNP and pain perception in Chinese cancer patients.

  4. result indicated that Caucasians carrying the G allele (AG + GG) of the A118G polymorphism in the mu-opioid receptor gene were more likely to be addicted to smoking compared with those with the AA homozygote

  5. we have identified for the first time a potential mechanism that involves the essential splicing factor (show SLU7 Proteins) ASF/SF2 (show SRSF1 Proteins) through which morphine regulates splicing specificity of the MOR encoding gene, OPRM1.

  6. OPRM1 A118G was not associated with nicotine craving in adolescent novice smokers.

  7. Significant differences in mean dose consumption were seen among the genotypic groups of the OPRM1 A118G and UGT2B7 C802T variants. These variants were found to predict codeine consumption in the cohort overall and among Caucasians

  8. Findings show that common OPRM1 intron 1 SNPs have replicable associations with heroin addiction, haplotype structure of rs3778150 and nearby SNPs may underlie the inconsistent associations between rs1799971 and heroin addiction

  9. These investigations represent a reverse translational approach to investigating how the OPRM1 A118G polymorphism alters mesolimbic responses to opioids, which may elucidate mechanisms influencing both opioid and alcohol abuse in human populations

  10. Study found that the OPRM1 A118G polymorphism produces significant variation in cortisol reactions to psychological stress among women

Mouse (Murine) Opioid Receptor, mu 1 (OPRM1) interaction partners

  1. findings indicate that G9a (show EHMT2 Proteins) contributes critically to transcriptional repression of MORs in primary sensory neurons in neuropathic pain. G9a (show EHMT2 Proteins) inhibitors may be used to enhance the opioid analgesic effect in the treatment of chronic neuropathic pain.

  2. In addition to generating a series of prototypic seven transmembrane domain G protein-coupled receptors, Oprm1 produces a set of truncated splice variants containing only six transmembrane domains through which selected opioids mediate a potent analgesia.

  3. Morphine treatment interferes with neuronal differentiation via MOR activation.

  4. These investigations represent a reverse translational approach to investigating how the OPRM1 A118G polymorphism alters mesolimbic responses to opioids, which may elucidate mechanisms influencing both opioid and alcohol abuse in human populations

  5. Results suggested that the MOPR A118G SNP results in a loss of receptor function in the mouse hippocampus

  6. Study demonstrates a functional role for Mu Opioid Splice Variant MOR-1K in a murine model of opioid-induced hyperalgesia.

  7. In the colon, monoglyceride lipase (show MGLL Proteins) deficiency causes increased mu opioid receptor sensitivity.

  8. This study resolves distinct ligand-directed mechanisms of JNK activation by mu opioid agonists and understanding ligand-directed signaling at MOR may improve opioid therapeutics.

  9. Study showed that the acquisition and escalation of heroin self-administration is greater in a mouse model of the OPRM1 A118G polymorphism

  10. In mu opioid receptor knockout mice, a sex difference was seen in alcohol consumption following social deprivation.

Cow (Bovine) Opioid Receptor, mu 1 (OPRM1) interaction partners

Rhesus Monkey Opioid Receptor, mu 1 (OPRM1) interaction partners

  1. Coactivation of mu opioid receptors with nociceptin receptors produces synergistic antinociception.

  2. Thisstudy adds to the growing literature showing that variation in the mu-opioid receptor gene OPRM1 is associated with social attachment and rejection.

  3. OPRM1 gene variation influences hypothalamic-pituitary-adrenal axis function in response to a variety of stressors.

  4. findings suggest a role for OPRM1 variation in the expression of attachment behavior, especially as a function of separation from the caregiver

Mu Opioid Receptor 1 (OPRM1) Protein Profile

Protein Summary

This gene encodes one of three opioid receptors. The mu opioid receptor is the principal target of endogenous opioid peptides and opioid analgesic agents such a s beta-endorphn and enkephalins. The NM_001008503.1:c.118A>G allele had been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Mu Opioid Receptor 1 (OPRM1)

  • opioid receptor, mu 1 (oprm1)
  • opioid receptor, mu 1 (OPRM1)
  • outer membrane efflux protein (oprM1)
  • outer membrane protein OprM (oprM1)
  • malate dehydrogenase 2, NAD (mitochondrial) (Mdh2)
  • opioid receptor, mu 1 (Oprm1)
  • retrotransposon-like 1 (Rtl1)
  • 6430411K18Rik protein
  • LMOR protein
  • M-OR-1 protein
  • Mar protein
  • Mart1 protein
  • MOP protein
  • MOP-R protein
  • mor protein
  • MOR-1 protein
  • MOR-1O protein
  • MOR1 protein
  • MORA protein
  • muOR protein
  • OPRM protein
  • OPRM1 protein
  • Oprrm1 protein
  • or2 protein
  • Peg11 protein
  • ZFOR2 protein

Protein level used designations for Opioid Receptor, mu 1 Proteins (OPRM1)

ZfMOR , mu-type opioid receptor , opioid receptor, mu 1 , mu-opioid receptor , outer membrane efflux protein , outer membrane protein OprM , malate dehydrogenase, mitochondrial , M-OR-1 , MOR-1 , MUOR1 , mu opioid receptor splice variant rMOR-1S , mu opioid receptor splice variant rMOR-1Z , opioid receptor B , micro opioid receptor isoform hMOR-1A2 , mu opiate receptor , mu opioid receptor hMOR-1a , MOP receptor , mu opioid receptor , mammalian retrotransposon derived protein 1 , paternally expressed gene 11 protein , retrotransposon-derived protein PEG11 , retrotransposon-like protein 1

GENE ID SPECIES
65088 Danio rerio
484041 Canis lupus familiaris
100033967 Equus caballus
100585188 Nomascus leucogenys
4606278 Azoarcus sp. BH72
10918065 Cupriavidus necator N-1
81829 Rattus norvegicus
25601 Rattus norvegicus
4988 Homo sapiens
18390 Mus musculus
100379267 Cavia porcellus
396802 Sus scrofa
281958 Bos taurus
472165 Pan troglodytes
574141 Macaca mulatta
353326 Mus musculus
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