Browse our anti-HIST4H4 (HIST4H4) Antibodies

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anti-Histone Cluster 4, H4 Antibodies (HIST4H4)
On are 7 Histone Cluster 4, H4 (HIST4H4) Antibodies from 5 different suppliers available. Additionally we are shipping HIST4H4 Proteins (2) and many more products for this protein. A total of 10 HIST4H4 products are currently listed.
list all antibodies Gene Name GeneID UniProt
HIST4H4 121504 P62805

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Human Histone Cluster 4, H4 (HIST4H4) interaction partners

  1. Data suggest post-translational modifications of histones, trimethylation of lysine 36 in H3 (H3K36me3) and acetylation of lysine 16 in H4 (H4K16ac), have roles in DNA damage repair; H3K36me3 stimulates H4K16ac upon DNA double-strand break; SETD2 (show SETD2 Antibodies), LEDGF (show PSIP1 Antibodies), and KAT5 (show KAT5 Antibodies) are required for these epigenetic changes. (SETD2 (show SETD2 Antibodies) = SET domain containing 2 (show SETD2 Antibodies); LEDGF (show PSIP1 Antibodies) = lens epithelium-derived growth factor (show PSIP1 Antibodies); KAT5 (show KAT5 Antibodies) = lysine acetyltransferase 5 (show KAT5 Antibodies))

  2. Data suggest that O-GlcNAc (show OGT Antibodies) transferase 1 (OGT1) specifically binds to, O-GlcNAcylates, and stabilizes nonspecific lethal protein3 (NSL3 (show KANSL3 Antibodies)); stabilization of NSL3 (show KANSL3 Antibodies) by OGT1 up-regulates global acetylation levels of histone 4 at Lys-5 (show AASDHPPT Antibodies), Lys (show LYZ Antibodies)-8, and Lys (show LYZ Antibodies)-16.

  3. Data show that Omomyc protein co-localized with proto-oncogene (show RAB1A Antibodies) protein c (show PROC Antibodies)-myc (c-Myc (show MYC Antibodies)), protein arginine methyltransferase 5 (PRMT5 (show PRMT5 Antibodies)) and histone H4 H4R3me2s-enriched chromatin domains.

  4. H4K12ac is regulated by estrogen receptor-alpha (show ESR1 Antibodies) and is associated with BRD4 (show BRD4 Antibodies) function and inducible transcription

  5. Systemic lupus erythematosus appears to be associated with an imbalance in histone acetyltransferases and histone deacetylase (show HDAC1 Antibodies) enzymes favoring pathologic H4 acetylation.

  6. Data indicate that MEP50 (show WDR77 Antibodies) WD repeat protein (show DCAF7 Antibodies) is essential for methylation of histones H4 and H2A by PRMT5 (show PRMT5 Antibodies) arginine methyltransferase.

  7. Sumoylated human histone H4 prevents chromatin compaction by inhibiting long-range internucleosomal interactions.

  8. Acetylation at lysine 5 of histone H4 associated with lytic gene promoters during reactivation of Kaposi's sarcoma-associated herpesvirus.

  9. An increase in histone H4 acetylation caused by hypoxia in human neuroblastoma (show ARHGEF16 Antibodies) cell lines corresponds to increased levels of N-myc (show MYCN Antibodies) transcription factor in these cells.

  10. Human PIH1 domain-containing protein 1 (PIH1) interacts directly with histone H4 and recruits the Brg1 (show SMARCA4 Antibodies)-SWI (show SMARCA1 Antibodies)/SNF (show SNRPA Antibodies) complex via SNF5 (show SMARCB1 Antibodies) to human rRNA genes.

HIST4H4 Antigen Profile

Antigen Summary

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails\\\\; instead, they contain a palindromic termination element.

Alternative names and synonyms associated with HIST4H4

  • histone cluster 4, H4 (HIST4H4) antibody
  • H4/p antibody

Protein level used designations for HIST4H4

histone H4 , histone 4, H4

121504 Homo sapiens
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