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Lanoix, Lacasse, Reiter, Vaillancourt: Melatonin: the watchdog of villous trophoblast homeostasis against hypoxia/reoxygenation-induced oxidative stress and apoptosis. in Molecular and cellular endocrinology 2013
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Rat (Rattus) Glutathione Peroxidase 1 ELISA Kit for Sandwich ELISA - ABIN416232
Rodrigues, Bergamaschi, Fernandes, Paredes-Gamero, Curi, Ferreira, Araujo, Punaro, Maciel, Nogueira, Higa: P2×(7) receptor in the kidneys of diabetic rats submitted to aerobic training or to N-acetylcysteine supplementation. in PLoS ONE 2014
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Human Glutathione Peroxidase 1 ELISA Kit for Sandwich ELISA - ABIN414656
Nalkiran, Turan, Arikan, Kahraman, Acar, Yaylim, Ergen: Determination of gene expression and serum levels of MnSOD and GPX1 in colorectal cancer. in Anticancer research 2014
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Human Glutathione Peroxidase 1 ELISA Kit for Sandwich ELISA - ABIN840169
Wu, Wang, Yang, Wei, Li, Pan, Huang, Wang, Qin, Zheng, Shima, Deng, Guo: Ambient particulate air pollution and circulating antioxidant enzymes: A repeated-measure study in healthy adults in Beijing, China. in Environmental pollution (Barking, Essex : 1987) 2015
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Human Glutathione Peroxidase 1 ELISA Kit for Sandwich ELISA - ABIN2684378
Takebe, Yarimizu, Saito, Hayashi, Nakamura, Yodoi, Nagasawa, Takahashi: A comparative study on the hydroperoxide and thiol specificity of the glutathione peroxidase family and selenoprotein P. in The Journal of biological chemistry 2002
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GPX1 is a gatekeeper restraining the oncogenic power of mitochondrial ROS (show ROS1 ELISA Kits) generated by SOD2 (show SOD2 ELISA Kits) is presented. Review.
Using lens epithelial cells derived from targeted inactivation of Prdx6 (show PRDX6 ELISA Kits)(-/-) gene and relative enzymatic and stability assays, we discovered dramatic increases in GSH-peroxidase (30%) and aiPLA2 (show PRDX6 ELISA Kits) (37%) activities and stability in the K122/142 R mutant, suggesting Sumo1 (show SUMO1 ELISA Kits) destabilized Prdx6 (show PRDX6 ELISA Kits) integrity
Coronary angiography findings indicated that individuals possessing Pro198Leu (CT) polymorphism were found to be associated with low erythrocyte GPX-1 activity and increased susceptibility for coronary artery disease.
High GPX1 expression is associated with Thyroid Tumors.
Data suggest that serum myeloperoxidase (show MPO ELISA Kits) (GPX1) levels are significantly associated with higher asymmetric dimethyl-arginine (ADMA) levels and up-regulation of circulating components of renin (show REN ELISA Kits)-angiotensin-aldosterone-system in patients with cardiovascular disease (CVD). Serum levels of ADMA and angiotensin II are more predictive for all-cause and CVD mortality compared to GPX1.
Pro198Leu of GPX1 might be a genetic risk factor in the development of Nephrolithiasis in South Iranian patients with lower Glutathione Peroxidase enzyme activity.
our data suggest that gene polymorphisms of GPX1 Pro198Leu and CAT C262T may have a protective role in the development of primary open-angle glaucoma in a Polish population.
GPx-1 expression deters the unfolded protein response following exposure to cigarette smoke
Knockdown of GPX1 in hucMSCs abrogated antioxidant and anti-apoptotic abilities of hucMSC-Ex and diminished the hepatoprotective effects of hucMSC-Ex in vitro and in vivo. Thus, hucMSC-Ex promote the recovery of hepatic oxidant injury through the delivery of GPX1.
The potential protective effect without statistical relationships were also observed for other genotypes and alleles studied polymorphic variants of antioxidant enzymes in CD and CAT- 262C / T and + 35 A / C SOD1 (show SOD1 ELISA Kits) in UC. Conducted our audit should be extended to more group of patients in order to assess whether or not to confirm the observed during analysis, the protective effect of CAT-262 C / T in ulcerative colitis and
Notably, CUEDC2 (show CUEDC2 ELISA Kits) promoted E3 ubiquitin ligases tripartite motif-containing 33 (TRIM33 (show TRIM33 ELISA Kits))-mediated the antioxidant enzyme, glutathione peroxidase 1 (GPX1) ubiquitination, and proteasome-dependent degradation.
GPx1 does not clearly exacerbate hyperoxia-induced increases in oxidative stress or lung injury but may alter pulmonary immune function.
Glutathione peroxidase 1 (GPx1) knockdown not only induced oxidative stress characterized by the increased production of reactive oxygen species (ROS (show ROS1 ELISA Kits)) but also caused reductive stress indicated by an elevation of glutathione (GSH)/oxidized GSH (GSSG) ratio.
Exposure to far infrared rays significantly protects acute restraint stress oxidative burdens via inhibition of JAK2 (show JAK2 ELISA Kits)/STAT3 (show STAT3 ELISA Kits) signaling by induction of GPx-1.
Genetic inhibition of Gpx1 potentiates cocaine-induced renal damage via activation of AT1R (show AGTRAP ELISA Kits) by inhibition of PI3K-Akt (show AKT1 ELISA Kits) signaling.
Glutathione peroxidase 1 deficiency attenuates concanavalin A-induced liver injury by induction of T-cell hyporesponsiveness through chronic reactive oxygen species exposure.
GPx1 was found to play a critical role in regulating pro-inflammatory pathways in vascular endothelium.
Plasmalogen enrichment via batyl alcohol supplementation attenuated atherosclerosis in ApoE (show APOE ELISA Kits)- and ApoE (show APOE ELISA Kits)/GPx1-deficient mice.
Gpx1 expression in the mouse skeletal muscle can be altered by both exercise and dyslipidemia through changes in DNA methylation (show HELLS ELISA Kits), leading to a fine regulation of free radical metabolism.
Studied the importance of selenium in bovine female reproductive function. Gene expression analysis revealed selenoprotein gene GPX1 was significantly up-regulated in large healthy follicles.
did not find any significant inhibition of bovine GPx-1 by (S)- or (R)-misonidazole.
Data indicate mRNA level and activity of GPx1 are regulated by level of selenium supplied to hepatocytes.
homocysteine decreases GPx1 activity by altering the translational mechanism
glutathione peroxidase-1 activity is decreased by aminoglycosides through interference with selenocysteine incorporation
GPx1 plays a key role in blocking the promotion of porcine circovirus type 2 replication
The developmental expression of GPX1 and thioredoxin reductase during fetal development and the effect of maternal selenium consumption on the expression of these proteins are reported.
This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
glutathione peroxidase Gpx1
, glutathione peroxidase
, putative glutathione peroxidase
, glutathione peroxidase 1
, cellular glutathione peroxidase
, selenium-dependent glutathione peroxidase 1
, cytosolic glutathione peroxidase