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Browse our GRP78 (HSPA5) ELISA Kits

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Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) ELISA Kits (HSPA5)
On are 38 Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) ELISA Kits from 9 different suppliers available. Additionally we are shipping GRP78 Antibodies (476) and GRP78 Proteins (27) and many more products for this protein. A total of 546 GRP78 products are currently listed.
AL022860, AU019543, baffled, Bip, cb865, D2Wsu17e, D2Wsu141e, fb60h09, fi36d04, GRP-78, Grp78, Hsce70, hspa5a, mBiP, MIF2, SEZ-7, Sez7, wu:fb60h09, wu:fi36d04, zgc:55994, zgc:77606
list all ELISA KIts Gene Name GeneID UniProt
HSPA5 3309 P11021
HSPA5 14828 P20029
HSPA5 25617 P06761

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GRP78 (HSPA5) ELISA Kits by Reactivity

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Top referenced GRP78 ELISA Kits

  1. Mouse (Murine) GRP78 ELISA Kit for Sandwich ELISA - ABIN425546 : Li, Zhu, Shen, Wan, Arnold, Peng: Deficiency of rac1 blocks NADPH oxidase activation, inhibits endoplasmic reticulum stress, and reduces myocardial remodeling in a mouse model of type 1 diabetes. in Diabetes 2010 (PubMed)

More ELISA Kits for GRP78 Interaction Partners

Xenopus laevis Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) interaction partners

  1. In amphibians, the association of BiP with unfolded protein and its possible role in aggresome function may be vital in the maintenance of cellular proteostasis.

  2. Hspa5 is essential for pronephros formation by mediating retinoic acid signaling.

Human Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) interaction partners

  1. The increased BiP/GRP78 expression was clarified as an independent prognostic marker for predicting worse outcome.

  2. Three mutants, T38A, T229A, and S300A, exhibited much lower activity than wild-type GRP78, indicating that the active sites of the ATPase (show DNAH8 ELISA Kits) are located at the negatively charged cavity.

  3. These data provide the first evidence that GRP78 rs391957 and rs430397 polymorphisms could serve as the markers to predict the risk and poor prognosis of NB.

  4. Taken together, our results indicate that GRP78 plays an important role in the development and progression of colorectal carcinoma (CRC (show CALR ELISA Kits)) and may have therapeutic potential for CRC (show CALR ELISA Kits) patients.

  5. plasma exposure resulted in expression of unfolded protein response (UPR) proteins such as glucoserelated protein 78 (GRP78), protein kinase (show CDK7 ELISA Kits) R (PKR (show PKLR ELISA Kits))like ER kinase (PERK (show EIF2AK3 ELISA Kits)), and inositolrequiring enzyme 1 (IRE1 (show ERN1 ELISA Kits)). Elevated expression of spliced Xbox binding protein 1 (XBP1 (show XBP1 ELISA Kits)) and CCAAT/enhancerbinding protein homologous protein (CHOP (show DDIT3 ELISA Kits)) further confirmed that ROS (show ROS1 ELISA Kits) generatedby NTGP induces apoptosis through the ER stress

  6. overexpression of calreticulin(CALR (show CALR ELISA Kits)) and heat shock 70kDa (show RPS6KB1 ELISA Kits) protein 5 (show CAPS ELISA Kits)(HSPA5) was further validated. CONCLUSION: Alltogether, abundant new candidate molecules, especially proteins related to ER-stress, were found to be involved in the pathogenesis of GD

  7. The measurement of the GRP78 level associated with the determination of intraperitoneal fat can be a useful predictor for endometrial cancer.

  8. Prion protein (show PRNP ELISA Kits) mutants inhibit Hrd1 (show SYVN1 ELISA Kits)-mediated retrotranslocation of misfolded proteins by depleting misfolded protein sensor BiP (show GDF10 ELISA Kits).

  9. Data revealed that Enterovirus 71 infection might cause upregulation and aberrant redistribution of GRP78/BiP to the cytosol, thereby facilitating virus replication.

  10. Data show that bortezomib/CX-4945 combination modulates endoplasmic reticulum (ER) stress/unfolded protein response (UPR) signaling by down-regulation BIP/Grp78 and activates NF-kappa B (show NFKB1 ELISA Kits) p65 (show GORASP1 ELISA Kits) pro-apoptotic functions.

Cow (Bovine) Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) interaction partners

  1. This paper reports the localization of both GRP78 and HSP60 (show HSPD1 ELISA Kits) on the luminal/apical surface of oviduct epithelial cells, their binding to spermatozoa, and the presence of endogenous HSP60 (show HSPD1 ELISA Kits) in the sperm midpiece.

  2. BiP is a master regulator of endoplasmic reticulum function, and its cleavage by subtilase cytotoxin represents a previously unknown trigger for cell death

Pig (Porcine) Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) interaction partners

  1. Over-expression of GRP78 enhances replication of Porcine Circovirus 2.

Mouse (Murine) Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) interaction partners

  1. Endoplasmic reticulum stress gene GRP78 is involved in signaling pathway during hepatitis B virus-mediated hepatocarcinogenesis.

  2. data show that Med inhibits ER stress-induced apoptosis and promotes osteoblast cell survival by targeting GRP78.

  3. These results suggested the important roles of endoplasmic reticulum-related chaperons, Bip and SIL1 (show SIL1 ELISA Kits), in Alzheimer's disease-like tau hyperphosphorylation.

  4. We show that chronic VPA treatment did not modify the ATXN3 (show ATXN3 ELISA Kits) inclusion load and astrogliosis in affected brain regions However, VPA chronic treatment was able to increase GRP78 protein levels at 30 weeks of age, one of its known neuroprotective effects

  5. these findings reveal a novel critical role of GRP78 in regulating ER stress-mediated apoptosis in cartilage development and the molecular mechanisms involved.

  6. ISM is a novel vascular permeability inducer that functions through cell-surface GRP78-mediated Src (show SRC ELISA Kits) activation as well as induction of apoptosis

  7. BIP increased surface CD19 molecule (show CD19 ELISA Kits) expression intensity and IL-10 (show IL10 ELISA Kits)(+), PD-L1 (show CD274 ELISA Kits)(hi) and FasL (show FASL ELISA Kits)(hi) B cells induced by BIP share the CD19 (show CD19 ELISA Kits)(hi) phenotype

  8. These studies demonstrate that BiP is critical for myelinating cell survival and contributes to the protective response of oligodendrocyte against inflammatory demyelination.

  9. These studies imply GRP78, but not GRP94 (show HSP90B1 ELISA Kits), is required for mammary gland development.

  10. The expression of GRP78 and Bcl-2 (show BCL2 ELISA Kits) was significantly higher in astrocytes pretreated with recombinant Shh (show SHH ELISA Kits). These findings suggest that the expression of Shh (show SHH ELISA Kits) may inhibit cell death by activating Bcl-2 (show BCL2 ELISA Kits) through a GRP78-dependent pathway.

Zebrafish Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) interaction partners

  1. Phosphatidylinositol deficient zebrafish have elevated hspa5 expression in the liver and hepatic lipid accumulation due to endoplasmic reticulum stress response.

GRP78 (HSPA5) Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER. As this protein interacts with many ER proteins, it may play a key role in monitoring protein transport through the cell.

Alternative names and synonyms associated with GRP78 (HSPA5)

  • 78 kDa glucose-regulated protein (CpipJ_CPIJ003550) Elisa Kit
  • heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) (HSPA5) Elisa Kit
  • 78 kDa glucose-regulated protein (grp78) Elisa Kit
  • BiP/GRP78 (LOC100533358) Elisa Kit
  • glucose-regulated protein 78 (BiP/grp78) Elisa Kit
  • glucose-regulated protein 78 (Tc00.1047053506585.40) Elisa Kit
  • glucose-regulated protein 78 (Tb11.02.5450) Elisa Kit
  • glucose-regulated protein 78 (Tb11.02.5500) Elisa Kit
  • glucose-regulated protein 78 (LmjF28.1200) Elisa Kit
  • Hsp70 family ATPase KAR2 (KAR2) Elisa Kit
  • glucose-regulated protein 78kDa (grp78) Elisa Kit
  • heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) (hspa5) Elisa Kit
  • heat shock 70 kDa protein 5a (hspa5) Elisa Kit
  • heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) (Hspa5) Elisa Kit
  • heat shock protein 5 (Hspa5) Elisa Kit
  • heat shock protein 5 (hspa5) Elisa Kit
  • AL022860 Elisa Kit
  • AU019543 Elisa Kit
  • baffled Elisa Kit
  • Bip Elisa Kit
  • cb865 Elisa Kit
  • D2Wsu17e Elisa Kit
  • D2Wsu141e Elisa Kit
  • fb60h09 Elisa Kit
  • fi36d04 Elisa Kit
  • GRP-78 Elisa Kit
  • Grp78 Elisa Kit
  • Hsce70 Elisa Kit
  • hspa5a Elisa Kit
  • mBiP Elisa Kit
  • MIF2 Elisa Kit
  • SEZ-7 Elisa Kit
  • Sez7 Elisa Kit
  • wu:fb60h09 Elisa Kit
  • wu:fi36d04 Elisa Kit
  • zgc:55994 Elisa Kit
  • zgc:77606 Elisa Kit

Protein level used designations for HSPA5

78 kDa glucose-regulated protein , GRP-78 , heat shock 70 kDa protein 5 , Protein 1603 , 78 kDa glucose-regulated protein homolog , luminal-binding protein , glucose-regulated protein 78 , glucose-regulated protein 78kDa , heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) , GRP 78 , biP , heavy-chain binding protein BiP , immunoglobulin heavy chain-binding protein , endoplasmic reticulum lumenal Ca(2+)-binding protein grp78 , glucose-regulated protein, 78kDa , XAP-1 antigen , glucose regulated protein, 78 kDa , heat shock 70kD protein 5 (glucose-regulated protein, 78kD) , heat shock 70kD protein 5 , heat shock 70kDa protein 5 (glucose-regulated protein) , steroidogenesis-activator polypeptide , bip

6034961 Culex quinquefasciatus
100173944 Pongo abelii
100196613 Salmo salar
100533358 Aplysia californica
543957 Solanum lycopersicum
3540481 Trypanosoma cruzi strain CL Brener
3665880 Trypanosoma brucei brucei strain 927/4 GUTat10.1
3665885 Trypanosoma brucei brucei strain 927/4 GUTat10.1
5653331 Leishmania major strain Friedlin
853418 Saccharomyces cerevisiae S288c
100135840 Oncorhynchus mykiss
379756 Xenopus laevis
464733 Pan troglodytes
703193 Macaca mulatta
100015941 Monodelphis domestica
100599238 Nomascus leucogenys
397850 Xenopus laevis
3309 Homo sapiens
415113 Bos taurus
396487 Gallus gallus
100731108 Cavia porcellus
407060 Sus scrofa
480726 Canis lupus familiaris
780447 Ovis aries
14828 Mus musculus
25617 Rattus norvegicus
378848 Danio rerio
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