Browse our GRP78 (HSPA5) ELISA Kits

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Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) ELISA Kits (HSPA5)
On are 41 Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) ELISA Kits from 10 different suppliers available. Additionally we are shipping GRP78 Antibodies (513) and GRP78 Proteins (25) and many more products for this protein. A total of 590 GRP78 products are currently listed.
AL022860, AU019543, baffled, Bip, cb865, D2Wsu17e, D2Wsu141e, fb60h09, fi36d04, GRP-78, Grp78, Hsce70, hspa5a, mBiP, MIF2, SEZ-7, Sez7, wu:fb60h09, wu:fi36d04, zgc:55994, zgc:77606
list all ELISA KIts Gene Name GeneID UniProt
HSPA5 3309 P11021
HSPA5 14828 P20029
HSPA5 25617 P06761

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Top referenced GRP78 ELISA Kits

  1. Mouse (Murine) GRP78 ELISA Kit for Sandwich ELISA - ABIN425546 : Li, Zhu, Shen, Wan, Arnold, Peng: Deficiency of rac1 blocks NADPH oxidase activation, inhibits endoplasmic reticulum stress, and reduces myocardial remodeling in a mouse model of type 1 diabetes. in Diabetes 2010 (PubMed)

More ELISA Kits for GRP78 Interaction Partners

Xenopus laevis Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) interaction partners

  1. In amphibians, the association of BiP with unfolded protein and its possible role in aggresome function may be vital in the maintenance of cellular proteostasis.

  2. Hspa5 is essential for pronephros formation by mediating retinoic acid signaling.

Human Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) interaction partners

  1. Inhibition of 17beta-HSD (show HSD17B3 ELISA Kits) 7 modulates breast cancer protein profile and enhances apoptosis by down-regulating GRP78.

  2. GALNT6 (show GALNT6 ELISA Kits)-induced O-glycosylation is critical for the stability, subcellular localization, and anti-apoptotic function of GRP78 protein in cancer cells. We also suggest that GRP78 might enhance the activity of GALNT6 (show GALNT6 ELISA Kits) in carcinogenesis through driving Golgi-to-ER relocation of GALNT6 (show GALNT6 ELISA Kits).

  3. BiP (show GDF10 ELISA Kits) binds to the unfolded state of MJ0366 and prevents its refolding, and that this effect is dependent on both the type and concentration of nucleotides.

  4. GRP78 control of fatty acid oxidation may represent a new homeostatic function for GRP78.

  5. in vitro and in vivo upregulation of Par-4 (show PAWR ELISA Kits) expression is indispensable for the trafficking of GRP78 to the cell membrane and subsequent apoptosis of cancer cell

  6. We found that 25-epi (show TFPI ELISA Kits) Ritterostatin GN1N induced cell death in melanoma cells at nanomolar concentrations, and this cell death was characterized by inhibition of GRP78 expression, increased expression of the ER stress marker CHOP (show DDIT3 ELISA Kits), loss of mitochondrial membrane potential, and lipidation of the autophagy marker protein LC3B (show MAP1LC3B ELISA Kits).

  7. Data suggest that, in breast cancer cells, expression of HSD17B5 (show AKR1C3 ELISA Kits) and expression of GRP78 (an apoptosis inhibitor) are strongly but negatively correlated; GRP78 knockdown decreases breast cancer cell viability whereas HSD17B5 (show AKR1C3 ELISA Kits) knockdown increases cell viability and cell proliferation. (HSD17B5 (show AKR1C3 ELISA Kits), 17-beta-hydroxysteroid dehydrogenase 5; GRP78, 78 kDa glucose-regulated protein)

  8. Western blot analysis of subcutaneously implanted AsPC-1 and BxPC-3 tumors as well as orthotopically implanted Panc-1 tumors demonstrated upregulation of BIP (show GDF10 ELISA Kits), CHOP (show DDIT3 ELISA Kits), and IRE1alpha (show ERN1 ELISA Kits) expression in the tumor lysates from penfluridol-treated mice as compared to tumors from control mice

  9. HSP78 (show CLPB ELISA Kits) on the cell surface was upregulated in human neuroblastoma (show ARHGEF16 ELISA Kits) cells (SK-N-SH) infected with Enterovirus 71

  10. we uncovered that folate deficiency could profoundly downregulate two prominent anti-apoptotic effectors including survivin (show BIRC5 ELISA Kits) and glucose-regulated protein-78. Silencing of either survivin (show BIRC5 ELISA Kits) or glucose-regulated protein-78 via small interfering RNA interfering technique established that both effectors could serve as reactive oxygen species sinker proteins

Cow (Bovine) Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) interaction partners

  1. This paper reports the localization of both GRP78 and HSP60 (show HSPD1 ELISA Kits) on the luminal/apical surface of oviduct epithelial cells, their binding to spermatozoa, and the presence of endogenous HSP60 (show HSPD1 ELISA Kits) in the sperm midpiece.

  2. BiP is a master regulator of endoplasmic reticulum function, and its cleavage by subtilase cytotoxin represents a previously unknown trigger for cell death

Pig (Porcine) Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) interaction partners

  1. Over-expression of GRP78 enhances replication of Porcine Circovirus 2.

Mouse (Murine) Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) interaction partners

  1. Upregulating HSF1 (show HSF1 ELISA Kits) relieves the tau toxicity in N2a-TauRD DeltaK280 by reducing CHOP (show DDIT3 ELISA Kits) and increasing HSP70 (show HSP70 ELISA Kits) a5 (BiP/GRP78). Our work reveals how the bidirectional crosstalk between the two stress response systems promotes early tau pathology and identifies HSF1 (show HSF1 ELISA Kits) being one likely key player in both systems.

  2. These results demonstrate a key role for GRP78 in alveolar epithelial cell survival.

  3. These results indicate that GRP78, an endoplasmic reticulum chaperon of the HSP70 (show HSP70 ELISA Kits) family, is a novel host factor involved at multiple steps of the Japanese encephalitis virus life cycle and could be a potential therapeutic target.

  4. Genetic or pharmacologic inhibition of the HSPA5-GPX4 (show GPX4 ELISA Kits) pathway enhanced gemcitabine sensitivity by disinhibiting ferroptosis in vitro and in both subcutaneous and orthotopic animal models of PDAC.

  5. The data presented indicate that the unfolded protein response is activated in fibrotic lung tissue and strongly localized to macrophages. GRP78- and CHOP (show DDIT3 ELISA Kits)-mediated macrophage apoptosis was found to protect against bleomycin-induced fibrosis.

  6. Endoplasmic reticulum stress gene GRP78 is involved in signaling pathway during hepatitis B virus-mediated hepatocarcinogenesis.

  7. data show that Med inhibits ER stress-induced apoptosis and promotes osteoblast cell survival by targeting GRP78.

  8. These results suggested the important roles of endoplasmic reticulum-related chaperons, Bip and SIL1 (show SIL1 ELISA Kits), in Alzheimer's disease-like tau hyperphosphorylation.

  9. We show that chronic VPA treatment did not modify the ATXN3 (show ATXN3 ELISA Kits) inclusion load and astrogliosis in affected brain regions However, VPA chronic treatment was able to increase GRP78 protein levels at 30 weeks of age, one of its known neuroprotective effects

  10. these findings reveal a novel critical role of GRP78 in regulating ER stress-mediated apoptosis in cartilage development and the molecular mechanisms involved.

Zebrafish Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) interaction partners

  1. Phosphatidylinositol deficient zebrafish have elevated hspa5 expression in the liver and hepatic lipid accumulation due to endoplasmic reticulum stress response.

GRP78 (HSPA5) Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER. As this protein interacts with many ER proteins, it may play a key role in monitoring protein transport through the cell.

Alternative names and synonyms associated with GRP78 (HSPA5)

  • 78 kDa glucose-regulated protein (CpipJ_CPIJ003550) Elisa Kit
  • heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) (HSPA5) Elisa Kit
  • 78 kDa glucose-regulated protein (grp78) Elisa Kit
  • BiP/GRP78 (LOC100533358) Elisa Kit
  • glucose-regulated protein 78 (BiP/grp78) Elisa Kit
  • glucose-regulated protein 78 (Tc00.1047053506585.40) Elisa Kit
  • glucose-regulated protein 78 (Tb11.02.5450) Elisa Kit
  • glucose-regulated protein 78 (Tb11.02.5500) Elisa Kit
  • glucose-regulated protein 78 (LmjF28.1200) Elisa Kit
  • Hsp70 family ATPase KAR2 (KAR2) Elisa Kit
  • glucose-regulated protein 78kDa (grp78) Elisa Kit
  • heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) (hspa5) Elisa Kit
  • heat shock 70 kDa protein 5a (hspa5) Elisa Kit
  • heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) (Hspa5) Elisa Kit
  • heat shock protein 5 (Hspa5) Elisa Kit
  • heat shock protein 5 (hspa5) Elisa Kit
  • AL022860 Elisa Kit
  • AU019543 Elisa Kit
  • baffled Elisa Kit
  • Bip Elisa Kit
  • cb865 Elisa Kit
  • D2Wsu17e Elisa Kit
  • D2Wsu141e Elisa Kit
  • fb60h09 Elisa Kit
  • fi36d04 Elisa Kit
  • GRP-78 Elisa Kit
  • Grp78 Elisa Kit
  • Hsce70 Elisa Kit
  • hspa5a Elisa Kit
  • mBiP Elisa Kit
  • MIF2 Elisa Kit
  • SEZ-7 Elisa Kit
  • Sez7 Elisa Kit
  • wu:fb60h09 Elisa Kit
  • wu:fi36d04 Elisa Kit
  • zgc:55994 Elisa Kit
  • zgc:77606 Elisa Kit

Protein level used designations for HSPA5

78 kDa glucose-regulated protein , GRP-78 , heat shock 70 kDa protein 5 , Protein 1603 , 78 kDa glucose-regulated protein homolog , luminal-binding protein , glucose-regulated protein 78 , glucose-regulated protein 78kDa , heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) , GRP 78 , biP , heavy-chain binding protein BiP , immunoglobulin heavy chain-binding protein , endoplasmic reticulum lumenal Ca(2+)-binding protein grp78 , glucose-regulated protein, 78kDa , XAP-1 antigen , glucose regulated protein, 78 kDa , heat shock 70kD protein 5 (glucose-regulated protein, 78kD) , heat shock 70kD protein 5 , heat shock 70kDa protein 5 (glucose-regulated protein) , steroidogenesis-activator polypeptide , bip

6034961 Culex quinquefasciatus
100173944 Pongo abelii
100196613 Salmo salar
100533358 Aplysia californica
543957 Solanum lycopersicum
3540481 Trypanosoma cruzi strain CL Brener
3665880 Trypanosoma brucei brucei strain 927/4 GUTat10.1
3665885 Trypanosoma brucei brucei strain 927/4 GUTat10.1
5653331 Leishmania major strain Friedlin
853418 Saccharomyces cerevisiae S288c
100135840 Oncorhynchus mykiss
379756 Xenopus laevis
464733 Pan troglodytes
703193 Macaca mulatta
100015941 Monodelphis domestica
100599238 Nomascus leucogenys
397850 Xenopus laevis
3309 Homo sapiens
415113 Bos taurus
396487 Gallus gallus
100731108 Cavia porcellus
407060 Sus scrofa
480726 Canis lupus familiaris
780447 Ovis aries
14828 Mus musculus
25617 Rattus norvegicus
378848 Danio rerio
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