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Browse our anti-PTPN1 (PTPN1) Antibodies

Full name:
anti-Protein tyrosine Phosphatase, Non-Receptor Type 1 Antibodies (PTPN1)
On www.antibodies-online.com are 173 Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1) Antibodies from 26 different suppliers available. Additionally we are shipping PTPN1 Kits (29) and PTPN1 Proteins (23) and many more products for this protein. A total of 238 PTPN1 products are currently listed.
Synonyms:
CPTP1, Ptp, PTP-1B, PTP-HA2, ptp1b, PTPN1, wu:fk54h03
list all antibodies Gene Name GeneID UniProt
PTPN1 5770 P18031
PTPN1 19246 P35821
PTPN1 24697 P20417

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anti-Human PTPN1 Antibodies:

anti-Mouse (Murine) PTPN1 Antibodies:

anti-Rat (Rattus) PTPN1 Antibodies:

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Top referenced anti-PTPN1 Antibodies

  1. Human Polyclonal PTPN1 Primary Antibody for WB - ABIN1882122 : Blincoe, Chidambaram, Salari, Bond, Evans, Gray-Kaufman, Griffey, Tranby, Garner-Johnson, Lee, Sorenson: Pharmacokinetic distribution of 67Cu(II)2[3,5-diisopropyl(carboxy-14C)salicylate]4 among murine tissues. in Current medicinal chemistry 2004 (PubMed)
    Show all 6 references for ABIN1882122

  2. Human Polyclonal PTPN1 Primary Antibody for EIA, WB - ABIN360735 : Ragab, Bodin, Viala, Chap, Payrastre, Ragab-Thomas: The tyrosine phosphatase 1B regulates linker for activation of T-cell phosphorylation and platelet aggregation upon FcgammaRIIa cross-linking. in The Journal of biological chemistry 2003 (PubMed)
    Show all 5 references for ABIN360735

  3. Chicken Monoclonal PTPN1 Primary Antibody for IF, IP - ABIN967772 : Bharadwaj, Ali, Ovsenek: Multiple components of the HSP90 chaperone complex function in regulation of heat shock factor 1 In vivo. in Molecular and cellular biology 2000 (PubMed)
    Show all 5 references for ABIN967772

  4. Mouse (Murine) Polyclonal PTPN1 Primary Antibody for WB - ABIN1881705 : Stuible, Tremblay: In control at the ER: PTP1B and the down-regulation of RTKs by dephosphorylation and endocytosis. in Trends in cell biology 2010 (PubMed)
    Show all 4 references for ABIN1881705

  5. Chicken Polyclonal PTPN1 Primary Antibody for WB - ABIN2782192 : Malecki, Cyganek, Mirkiewicz-Sieradzka, Wolkow, Wanic, Skupien, Solnica, Sieradzki: Alanine variant of the Pro12Ala polymorphism of the PPARgamma gene might be associated with decreased risk of diabetic retinopathy in type 2 diabetes. in Diabetes research and clinical practice 2008 (PubMed)

  6. Human Monoclonal PTPN1 Primary Antibody for ELISA, WB - ABIN411571 : Gan, Zhang, Buckels, Paterson, Jiang, Clemens, Zhang, Du, Chang, Frank: IGF-1R modulation of acute GH-induced STAT5 signaling: role of protein tyrosine phosphatase activity. in Molecular endocrinology (Baltimore, Md.) 2013 (PubMed)

More Antibodies against PTPN1 Interaction Partners

Human Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1) interaction partners

  1. PTP1B directly regulates STAT5 (show STAT5A Antibodies) phosphorylation and its activation via the cAMP/PKA pathway downstream of the 5-HT7 (show HTR7 Antibodies) receptor is involved in the suppression of beta-casein (show CSN2 Antibodies) expression in MCF-12A cells

  2. On EGF (show EGF Antibodies) stimulation, complexes containing Mena (show EGFR Antibodies) and PTP1B are recruited to the EGFR (show EGFR Antibodies), causing receptor dephosphorylation and leading to decreased motility responses.

  3. PTP1B dephosphorylates PITX1 (show PITX1 Antibodies) to weaken its protein stability and the transcriptional activity for p120RasGAP (show RASA1 Antibodies) gene expression

  4. our data indicate that by targeting PTP1B, miR (show MLXIP Antibodies)-744 plays a feed-forward role in regulating type I IFN signaling pathway.

  5. O-GlcNAcylation of PTP1B can influence insulin (show INS Antibodies) signal transduction by modulating its own phosphatase activity, which participates in the process of hepatic insulin (show INS Antibodies) resistance.

  6. Blockade of the interaction between Bcr-Abl (show ABL1 Antibodies) and PTB1B by small molecule SBF-1 (show SBF1 Antibodies) to overcomes imatinib-resistance of K562 cells.

  7. the multiple roles of PTP1B in liver diseases will be presented, with respect to liver regeneration, drug-induced liver disease, non-alcoholic fatty liver disease (NAFLD (show TSC2 Antibodies)) and hepatocellular carcinoma--{REVIEW}

  8. PTP1B amplification predicts poor survival of gastric cancer patients.

  9. the hydrogen bond and energy decomposition analyses indicate that apart from residue 181, point mutations have influence on the interactions of substrate with several residues in the active site of PTP1B

  10. Nck1 (show NCK1 Antibodies) depletion induces activation of the PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) pathway by attenuating PTP1B protein expression

Mouse (Murine) Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1) interaction partners

  1. Deletion of Ptp1b in POMC (show POMC Antibodies) neurons protects from leptin (show LEP Antibodies)- and sympatho-mediated increases in BP.

  2. these data provide first evidence for a key regulatory role for PTP1B in mediating a central dendritic cells function of initiating adaptive immune responses in response to innate immune cell activation.

  3. These findings indicated that improvement of insulin (show INS Antibodies) sensitivity and hypoglycemic effects of ME may be attributed to the inhibition of PTP1B. Thereby, we pioneered the inhibitory potential of ME targeted on PTP1B as anti-T2DM drug discovery.

  4. This study presents PTP1B as a mechanism-based therapeutic target for RTT, validating a unique strategy for treating the disease by modifying signal transduction pathways with small-molecule drugs.

  5. Studied the liver-specific role of PTP1B in GH signaling.

  6. Superoxide anion radicals induce IGF-1 (show IGF1 Antibodies) resistance through activation of PTP1B and PTEN (show PTEN Antibodies).

  7. Fumosorinone increased glucose uptake and improved insulin (show INS Antibodies) resistance by down-regulating the expression of PTP1B and activating the insulin (show INS Antibodies) signaling pathway, suggesting that it may possess antidiabetic properties.

  8. that PTP1B knockout offers cardioprotection against high fat diet intake through activation of AMPK (show PRKAA1 Antibodies).

  9. PTP1B up-regulation in podocytes induces a migratory response by activating Src-family kinases and focal adhesion kinase, leading to foot process effacement and proteinuria

  10. Complement-mediated glomerular injury is reduced by inhibition of protein-tyrosine phosphatase 1B.

PTPN1 Antigen Profile

Antigen Summary

The protein encoded by this gene is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzymatic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP has been shown to act as a negative regulator of insulin signaling by dephosphorylating the phosphotryosine residues of insulin receptor kinase. This PTP was also reported to dephosphorylate epidermal growth factor receptor kinase, as well as JAK2 and TYK2 kinases, which implicated the role of this PTP in cell growth control, and cell response to interferon stimulation.

Alternative names and synonyms associated with PTPN1

  • protein tyrosine phosphatase, non-receptor type 1 (PTPN1) antibody
  • protein tyrosine phosphatase, non-receptor type 1 (Ptpn1) antibody
  • protein tyrosine phosphatase, non-receptor type 1 (ptpn1) antibody
  • CPTP1 antibody
  • Ptp antibody
  • PTP-1B antibody
  • PTP-HA2 antibody
  • ptp1b antibody
  • PTPN1 antibody
  • wu:fk54h03 antibody

Protein level used designations for PTPN1

protein tyrosine phosphatase, non-receptor type 1 , tyrosine-protein phosphatase non-receptor type 1 , tyrosine-protein phosphatase non-receptor type 1-like , protein tyrosine phosphatase, placental , protein-tyrosine phosphatase 1B , protein-protein-tyrosine phosphatase HA2 , protein-tyrosine phosphatase HA2 , PTP-1B , fk54h03 , protein tyrosine phosphatase 1b , non-receptor protein tyrosine phosphatase , phosphoprotein phosphatase , tyrosine phosphatase 1B

GENE ID SPECIES
469970 Pan troglodytes
702016 Macaca mulatta
100172151 Pongo abelii
100354834 Oryctolagus cuniculus
100387823 Callithrix jacchus
100481720 Ailuropoda melanoleuca
5770 Homo sapiens
19246 Mus musculus
24697 Rattus norvegicus
30081 Danio rerio
444514 Xenopus laevis
395688 Gallus gallus
477263 Canis lupus familiaris
396667 Sus scrofa
508658 Bos taurus
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