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Browse our anti-TICAM1 (TICAM1) Antibodies

Full name:
anti-Toll-Like Receptor Adaptor Molecule 1 Antibodies (TICAM1)
On www.antibodies-online.com are 77 Toll-Like Receptor Adaptor Molecule 1 (TICAM1) Antibodies from 26 different suppliers available. Additionally we are shipping TICAM1 Kits (6) and TICAM1 Proteins (3) and many more products for this protein. A total of 93 TICAM1 products are currently listed.
Synonyms:
AW046014, AW547018, IIAE6, MyD88-3, PRVTIRB, TICAM-1, trif
list all antibodies Gene Name GeneID UniProt
TICAM1 148022 Q8IUC6
TICAM1 106759 Q80UF7
TICAM1 363328  

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anti-Human TICAM1 Antibodies:

anti-Mouse (Murine) TICAM1 Antibodies:

anti-Rat (Rattus) TICAM1 Antibodies:

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Top referenced anti-TICAM1 Antibodies

  1. Human Polyclonal TICAM1 Primary Antibody for WB - ABIN1881885 : Bin, Xu, Shu: TIRP, a novel Toll/interleukin-1 receptor (TIR) domain-containing adapter protein involved in TIR signaling. in The Journal of biological chemistry 2003 (PubMed)
    Show all 5 references for ABIN1881885

  2. Human Polyclonal TICAM1 Primary Antibody for EIA, IHC (p) - ABIN501042 : ONeill, Fitzgerald, Bowie: The Toll-IL-1 receptor adaptor family grows to five members. in Trends in immunology 2003 (PubMed)
    Show all 4 references for ABIN501042

  3. Human Polyclonal TICAM1 Primary Antibody for DB, EIA - ABIN493536 : Fitzgerald, Golenbock: Immunology. The shape of things to come. in Science (New York, N.Y.) 2007 (PubMed)
    Show all 3 references for ABIN493536

  4. Human Polyclonal TICAM1 Primary Antibody for IP, WB - ABIN1169062 : Carty, Goodbody, Schröder, Stack, Moynagh, Bowie: The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling. in Nature immunology 2006 (PubMed)
    Show all 3 references for ABIN1169062

More Antibodies against TICAM1 Interaction Partners

Human Toll-Like Receptor Adaptor Molecule 1 (TICAM1) interaction partners

  1. involved in signaling that moderates the expression of heme oxygenase1 and il-8 (show IL8 Antibodies) after keratinocytes exposure to dinitrochlorobenzene

  2. Using bone marrow derived macrophages from knockout mice we demonstrate that hBD3 (show DEFB103A Antibodies) suppresses the polyI:C-induced TLR3 (show TLR3 Antibodies) response mediated by TICAM1 (TRIF), while exacerbating the cytoplasmic response through MDA5 (IFIH1 (show IFIH1 Antibodies)) and MAVS (IPS1/CARDIF (show MAVS Antibodies)).

  3. signaling through TRIF (show TRIM69 Antibodies) is important for the inflammatory response of AngII-induced abdominal aortic aneurysm formation

  4. Data show that toll-like receptor 3 (show TLR3 Antibodies)/TRIF (show TRIM69 Antibodies) protein signalling regulates cytokines IL-32 (show IL32 Antibodies) and IFN-beta (show IFNB1 Antibodies) secretion by activation of receptor-interacting protein-1 (RIP-1 (show RIPK1 Antibodies)) and tumour necrosis factor (show TNF Antibodies) receptor-associated factor 6 (TRAF6 (show TRAF6 Antibodies)) in cornea epithelial cells.

  5. WDFY1 (show WDFY1 Antibodies) mediates TLR3 (show TLR3 Antibodies)/TLR4 (show TLR4 Antibodies) signaling by recruiting TRIF (show TRIM69 Antibodies).

  6. In mic (show AGT Antibodies)e with nonfunctional TRIF (Trif(mut) mice), Ang II-induced hypertension and cardiac hypertrophy were abrogated, and proinflammatory gene expression in heart and kid (show TRIM69 Antibodies)neys was unchanged or decreased. These results indicate that Ang II induces activation of a proinflammatory innate immune response, causing hypertension and cardiac hypertrophy, which require functional adaptor protein TRIF-mediated pathways.

  7. TRIF (show TRIM69 Antibodies) promotes angiotensin II-induced cross-talk between fibroblasts and macrophages in atrial fibrosis.

  8. amino-terminal 21 amino acid sequence is crucial for TRAF3 (show TRAF3 Antibodies) association, protein stability and activation of the IFN pathway

  9. required, in combination with MyD88 (show MYD88 Antibodies), for TLR4 (show TLR4 Antibodies)-mediated proinflammatory dendritic cell differentiation

  10. findings show that TRIF (show TRIM69 Antibodies) activates IRF3 (show IRF3 Antibodies) through a phosphorylation-dependent mechanism; results reveal that phosphorylation of innate adaptor proteins is an essential and conserved mechanism that selectively recruits IRF3 (show IRF3 Antibodies) to activate the type I IFN pathway

Mouse (Murine) Toll-Like Receptor Adaptor Molecule 1 (TICAM1) interaction partners

  1. The authors demonstrate that, in addition to MyD88 (show MYD88 Antibodies), Yersinia pseudotuberculosis inhibits TRIF (show RNF138 Antibodies) signaling through the type III secretion system effector YopJ.

  2. Results show that toll (show TLR4 Antibodies)/IL-1 (show IL1A Antibodies) domain-containing adaptor inducing IFN-beta (show IFNB1 Antibodies) (TRIF (show RNF138 Antibodies)) is essential for Toll (show TLR4 Antibodies)-like receptors TLR3 (show TLR3 Antibodies)- and TLR4 (show TLR4 Antibodies)-mediated innate immune responses in peritoneal mesothelial cells (PMCs).

  3. Data show that annexin A2 (AnxA2 (show ANXA2 Antibodies)) directly exerted negative regulation of inflammatory responses through Toll-like receptor 4 (TLR4 (show TLR4 Antibodies))-initiated TRAM protein (show TRAM2 Antibodies)-TRIF (show RNF138 Antibodies) protein pathway occurring on endosomes.

  4. ProTalpha preconditioning-induced prevention of retinal ischemic damage is mediated by selective activation of the TIR-domain-containing adapter-inducing interferon-beta (show IFNB1 Antibodies) interferon regulatory factor 3 (show IRF3 Antibodies) pathway downstream of toll-like receptor 4 (show TLR4 Antibodies) in microglia

  5. signaling through TRIF (show RNF138 Antibodies) is important for the inflammatory response of AngII-induced abdominal aortic aneurysm formation

  6. analysis of how MyD88 (show MYD88 Antibodies) and TRIF (show RNF138 Antibodies) affect TLR4 (show TLR4 Antibodies) activation

  7. Ang II (show AGT Antibodies) induces activation of a proinflammatory innate immune response, causing hypertension and cardiac hypertrophy. These effects require functional adaptor protein TRIF (show RNF138 Antibodies)-mediated pathways.

  8. Data indicate that Toll-like receptor 4 (TLR4 (show TLR4 Antibodies)) endocytosis and the TIR-domain-containing adapter-inducing IFN-beta (show IFNB1 Antibodies) (TRIF (show RNF138 Antibodies))-signaling pathway in macrophages during endotoxin tolerance in the absence of cluster of differentiation 14 (CD14 (show CD14 Antibodies)).

  9. A MAVS (show MAVS Antibodies)/TICAM-1-independent interferon (show IFNA Antibodies)-inducing pathway contributes to regulation of hepatitis B virus replication

  10. Trif was mainly present in the ganglion cell layer(GCL)after ischemia-reperfusion (IR) injury. Retinas of TrifKO mice had a significantly reduced neurotoxic pro-inflammatory response and significantly increased survival of the GCL neurons after IR.

Cow (Bovine) Toll-Like Receptor Adaptor Molecule 1 (TICAM1) interaction partners

  1. Inhibition of the Toll (show TLR4 Antibodies)/interleukin-1 receptor (TIR) domain-containing adapter-inducing interferon-beta (show IFNB1 Antibodies) signaling reduced permeability changes and apoptosis in endothelial cells exposed to lipopolysaccharide.

Zebrafish Toll-Like Receptor Adaptor Molecule 1 (TICAM1) interaction partners

  1. 3D-models of rohu TLR3 (show TLR3 Antibodies)-TIR and zebrafish TRIF

  2. The role of zebrafish (Danio rerio) TICAM1 in activating NF-kappaB (show NFKB1 Antibodies) and zebrafish type I IFN was described.

  3. study focuses on the functional characterization of zebrafish TRIF; results show that the full length cDNA of zebrafish TRIF encodes a protein of 556 amino acids; TRIF is able to induce the IFN promoter as well as activate NF-kappaB (show NFKB1 Antibodies) response promoter

TICAM1 Antigen Profile

Antigen Summary

This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response.

Alternative names and synonyms associated with TICAM1

  • toll-like receptor adaptor molecule 1 (TICAM1) antibody
  • toll-like receptor adaptor molecule 1 (LOC100231928) antibody
  • toll-like receptor adaptor molecule 1 (Ticam1) antibody
  • toll-like receptor adaptor molecule 1 (ticam1) antibody
  • AW046014 antibody
  • AW547018 antibody
  • IIAE6 antibody
  • MyD88-3 antibody
  • PRVTIRB antibody
  • TICAM-1 antibody
  • trif antibody

Protein level used designations for TICAM1

TIR domain-containing adapter molecule 1 , TIR domain containing adaptor inducing interferon-beta , toll-interleukin I receptor domain containing adaptor molecule 1 , toll-like receptor adaptor molecule 1 , TIR domain-containing adapter molecule 1-like , TIR domain-containing adapter protein inducing IFN-beta , proline-rich, vinculin and TIR domain-containing protein B , putative NF-kappa-B-activating protein 502H , toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta , TIR domain-containing adaptor inducing interferon-beta , toll-interleukin 1 receptor domain-containing adapter protein inducing interferon-beta , TICAM-1 , TIR-domain containing adaptor inducing IFN-beta , TRIF/TICAM1

GENE ID SPECIES
468677 Pan troglodytes
574294 Macaca mulatta
611852 Canis lupus familiaris
100062414 Equus caballus
100231928 Taeniopygia guttata
100405343 Callithrix jacchus
100588929 Nomascus leucogenys
148022 Homo sapiens
106759 Mus musculus
510427 Bos taurus
363328 Rattus norvegicus
403147 Danio rerio
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