Browse our anti-TICAM1 (TICAM1) Antibodies

Full name:
anti-Toll-Like Receptor Adaptor Molecule 1 Antibodies (TICAM1)
On are 81 Toll-Like Receptor Adaptor Molecule 1 (TICAM1) Antibodies from 26 different suppliers available. Additionally we are shipping TICAM1 Kits (7) and TICAM1 Proteins (5) and many more products for this protein. A total of 99 TICAM1 products are currently listed.
AW046014, AW547018, IIAE6, MyD88-3, PRVTIRB, TICAM-1, trif
list all antibodies Gene Name GeneID UniProt
TICAM1 148022 Q8IUC6
TICAM1 106759 Q80UF7
TICAM1 363328  

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anti-Human TICAM1 Antibodies:

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Top referenced anti-TICAM1 Antibodies

  1. Human Polyclonal TICAM1 Primary Antibody for ICC, IF - ABIN266066 : Hoebe, Du, Georgel, Janssen, Tabeta, Kim, Goode, Lin, Mann, Mudd, Crozat, Sovath, Han, Beutler: Identification of Lps2 as a key transducer of MyD88-independent TIR signalling. in Nature 2003 (PubMed)
    Show all 23 references for 266066

  2. Human Polyclonal TICAM1 Primary Antibody for WB - ABIN1881885 : Bin, Xu, Shu: TIRP, a novel Toll/interleukin-1 receptor (TIR) domain-containing adapter protein involved in TIR signaling. in The Journal of biological chemistry 2003 (PubMed)
    Show all 5 references for 1881885

  3. Human Polyclonal TICAM1 Primary Antibody for EIA, IHC (p) - ABIN501042 : ONeill, Fitzgerald, Bowie: The Toll-IL-1 receptor adaptor family grows to five members. in Trends in immunology 2003 (PubMed)
    Show all 4 references for 501042

  4. Human Polyclonal TICAM1 Primary Antibody for IP, WB - ABIN1169062 : Carty, Goodbody, Schröder, Stack, Moynagh, Bowie: The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling. in Nature immunology 2006 (PubMed)
    Show all 3 references for 1169062

  5. Human Polyclonal TICAM1 Primary Antibody for DB, EIA - ABIN493536 : Fitzgerald, Golenbock: Immunology. The shape of things to come. in Science (New York, N.Y.) 2007 (PubMed)
    Show all 3 references for 493536

  6. Human Polyclonal TICAM1 Primary Antibody for ELISA, ICC - ABIN4362350 : Shi, Kehrl: MyD88 and Trif target Beclin 1 to trigger autophagy in macrophages. in The Journal of biological chemistry 2008 (PubMed)

More Antibodies against TICAM1 Interaction Partners

Human Toll-Like Receptor Adaptor Molecule 1 (TICAM1) interaction partners

  1. Therefore, Seneca Valley virus suppressed antiviral interferon (show IFNA Antibodies) production to escape host antiviral innate immune responses by cleaving host adaptor molecules MAVS (show MAVS Antibodies), TRIF (show TRIM69 Antibodies), and TANK by its 3C protease.

  2. TRIF (show TRIM69 Antibodies) gene may contribute to susceptibility of T2DM.

  3. The NF-kappaB (show NFKB1 Antibodies) activated by dsRNA appears not to be the canonical p65 (show GORASP1 Antibodies)/p50 (show CD40 Antibodies) heterodimers.

  4. We confirmed associations with papillary thyroid cancer and SNPs in FOXE1 (show FOXE1 Antibodies)/HEMGN, SERPINA5 (show SERPINA5 Antibodies) (rs2069974), FTO (show FTO Antibodies) (rs8047395), EVPL (show EVPL Antibodies) (rs2071194), TICAM1 (rs8120) and SCARB1 (show SCARB1 Antibodies) (rs11057820) genes. We found associations with SNPs in FOXE1 (show FOXE1 Antibodies), SERPINA5 (show SERPINA5 Antibodies), FTO (show FTO Antibodies), TICAM1 and HSPA6 (show HSPA6 Antibodies) and and follicular thyroid cancer

  5. IL-12p70 production requires uptake of Streptococcus pneumoniae as well as the presence of the adaptor molecule TRIF (show TRIM69 Antibodies).

  6. TIRF high-content imaging system simultaneously showed the expression pattern of EGFRs and EC50 value for CPT (show CHPT1 Antibodies)-induced apoptosis and necrosis in MCF-7, SK-BR-3 and JIMT-1 cancer cell line

  7. involved in signaling that moderates the expression of heme oxygenase1 and il-8 (show IL8 Antibodies) after keratinocytes exposure to dinitrochlorobenzene

  8. Using bone marrow derived macrophages from knockout mice we demonstrate that hBD3 (show DEFB103A Antibodies) suppresses the polyI:C-induced TLR3 (show TLR3 Antibodies) response mediated by TICAM1 (TRIF), while exacerbating the cytoplasmic response through MDA5 (IFIH1 (show IFIH1 Antibodies)) and MAVS (IPS1/CARDIF (show MAVS Antibodies)).

  9. signaling through TRIF (show TRIM69 Antibodies) is important for the inflammatory response of AngII-induced abdominal aortic aneurysm formation

  10. Data show that toll-like receptor 3 (show TLR3 Antibodies)/TRIF (show TRIM69 Antibodies) protein signalling regulates cytokines IL-32 (show IL32 Antibodies) and IFN-beta (show IFNB1 Antibodies) secretion by activation of receptor-interacting protein-1 (RIP-1 (show RIPK1 Antibodies)) and tumour necrosis factor (show TNF Antibodies) receptor-associated factor 6 (TRAF6 (show TRAF6 Antibodies)) in cornea epithelial cells.

Mouse (Murine) Toll-Like Receptor Adaptor Molecule 1 (TICAM1) interaction partners

  1. TRIF (show RNF138 Antibodies) and STING interacted directly, through their carboxy-terminal domains, to promote STING dimerization, intermembrane translocation, and signaling.

  2. Upon stimulation with poly(I:C), malaria parasite-infected red blood cells (iRBCs), or vesicular stomatitis virus (VSV), FOSL1 (show FOSL1 Antibodies) "translocated" from the nucleus to the cytoplasm, where it inhibited the interactions between TNF receptor-associated factor 3 (TRAF3 (show TRAF3 Antibodies)), TIR domain-containing adapter inducing IFN-beta (show IFNB1 Antibodies) (TRIF (show RNF138 Antibodies)), and Tank-binding kinase 1 (TBK1 (show TBK1 Antibodies)) via impairing K63-linked polyubiquitination of TRAF3 (show TRAF3 Antibodies) and TRIF (show RNF138 Antibodies).

  3. These results suggested the importance of TRIF (show RNF138 Antibodies) in TLR2 (show TLR2 Antibodies) mediated foam cell formation via inflammatory mediators, including MCP-1 (show CPT1B Antibodies).

  4. DENV replication and IFNalpha/beta, TNF-alpha (show TNF Antibodies), IL-12 (show IL12A Antibodies) and IL-18 (show IL18 Antibodies) in infected cultures at 24h were found. All of these parameters were significantly decreased after TRIF (show RNF138 Antibodies), MYD88 (show MYD88 Antibodies) or NF-kB inhibition

  5. The authors demonstrate that, in addition to MyD88 (show MYD88 Antibodies), Yersinia pseudotuberculosis inhibits TRIF (show RNF138 Antibodies) signaling through the type III secretion system effector YopJ.

  6. Results show that toll (show TLR4 Antibodies)/IL-1 (show IL1A Antibodies) domain-containing adaptor inducing IFN-beta (show IFNB1 Antibodies) (TRIF (show RNF138 Antibodies)) is essential for Toll (show TLR4 Antibodies)-like receptors TLR3 (show TLR3 Antibodies)- and TLR4 (show TLR4 Antibodies)-mediated innate immune responses in peritoneal mesothelial cells (PMCs).

  7. Data show that annexin A2 (AnxA2 (show ANXA2 Antibodies)) directly exerted negative regulation of inflammatory responses through Toll-like receptor 4 (TLR4 (show TLR4 Antibodies))-initiated TRAM protein (show TRAM2 Antibodies)-TRIF (show RNF138 Antibodies) protein pathway occurring on endosomes.

  8. ProTalpha preconditioning-induced prevention of retinal ischemic damage is mediated by selective activation of the TIR-domain-containing adapter-inducing interferon-beta (show IFNB1 Antibodies) interferon regulatory factor 3 (show IRF3 Antibodies) pathway downstream of toll-like receptor 4 (show TLR4 Antibodies) in microglia

  9. signaling through TRIF (show RNF138 Antibodies) is important for the inflammatory response of AngII-induced abdominal aortic aneurysm formation

  10. analysis of how MyD88 (show MYD88 Antibodies) and TRIF (show RNF138 Antibodies) affect TLR4 (show TLR4 Antibodies) activation

Cow (Bovine) Toll-Like Receptor Adaptor Molecule 1 (TICAM1) interaction partners

  1. Inhibition of the Toll (show TLR4 Antibodies)/interleukin-1 receptor (TIR) domain-containing adapter-inducing interferon-beta (show IFNB1 Antibodies) signaling reduced permeability changes and apoptosis in endothelial cells exposed to lipopolysaccharide.

Zebrafish Toll-Like Receptor Adaptor Molecule 1 (TICAM1) interaction partners

  1. 3D-models of rohu TLR3 (show TLR3 Antibodies)-TIR and zebrafish TRIF

  2. The role of zebrafish (Danio rerio) TICAM1 in activating NF-kappaB (show NFKB1 Antibodies) and zebrafish type I IFN was described.

  3. study focuses on the functional characterization of zebrafish TRIF; results show that the full length cDNA of zebrafish TRIF encodes a protein of 556 amino acids; TRIF is able to induce the IFN promoter as well as activate NF-kappaB (show NFKB1 Antibodies) response promoter

TICAM1 Antigen Profile

Antigen Summary

This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response.

Alternative names and synonyms associated with TICAM1

  • toll-like receptor adaptor molecule 1 (TICAM1) antibody
  • toll-like receptor adaptor molecule 1 (LOC100231928) antibody
  • toll-like receptor adaptor molecule 1 (Ticam1) antibody
  • toll-like receptor adaptor molecule 1 (ticam1) antibody
  • AW046014 antibody
  • AW547018 antibody
  • IIAE6 antibody
  • MyD88-3 antibody
  • PRVTIRB antibody
  • TICAM-1 antibody
  • trif antibody

Protein level used designations for TICAM1

TIR domain-containing adapter molecule 1 , TIR domain containing adaptor inducing interferon-beta , toll-interleukin I receptor domain containing adaptor molecule 1 , toll-like receptor adaptor molecule 1 , TIR domain-containing adapter molecule 1-like , TIR domain-containing adapter protein inducing IFN-beta , proline-rich, vinculin and TIR domain-containing protein B , putative NF-kappa-B-activating protein 502H , toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta , TIR domain-containing adaptor inducing interferon-beta , toll-interleukin 1 receptor domain-containing adapter protein inducing interferon-beta , TICAM-1 , TIR-domain containing adaptor inducing IFN-beta , TRIF/TICAM1

468677 Pan troglodytes
574294 Macaca mulatta
611852 Canis lupus familiaris
100062414 Equus caballus
100231928 Taeniopygia guttata
100405343 Callithrix jacchus
100588929 Nomascus leucogenys
148022 Homo sapiens
106759 Mus musculus
510427 Bos taurus
363328 Rattus norvegicus
403147 Danio rerio
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