Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species and application
anti-Human TLR7 Antibodies:
anti-Mouse (Murine) TLR7 Antibodies:
anti-Rat (Rattus) TLR7 Antibodies:
Go to our pre-filtered search.
Human Polyclonal TLR7 Primary Antibody for FACS, ICC - ABIN4360352
Palazzo, Gariboldi, Zanobbio, Dusio, Selleri, Bedoni, Balsari, Rumio: Cross-talk among Toll-like receptors and their ligands. in International immunology 2008
Show all 41 Pubmed References
Human Polyclonal TLR7 Primary Antibody for FACS, ICC - ABIN4360350
Kalali, Köllisch, Mages, Müller, Bauer, Wagner, Ring, Lang, Mempel, Ollert: Double-stranded RNA induces an antiviral defense status in epidermal keratinocytes through TLR3-, PKR-, and MDA5/RIG-I-mediated differential signaling. in Journal of immunology (Baltimore, Md. : 1950) 2008
Show all 20 Pubmed References
Human Polyclonal TLR7 Primary Antibody for FACS - ABIN4360348
Xirakia, Koltsida, Stavropoulos, Thanassopoulou, Aidinis, Sideras, Andreakos: Toll-like receptor 7-triggered immune response in the lung mediates acute and long-lasting suppression of experimental asthma. in American journal of respiratory and critical care medicine 2010
Show all 18 Pubmed References
Human Polyclonal TLR7 Primary Antibody for FACS, IHC (fro) - ABIN252541
Chen, Nagaraju, Bakay, McIntyre, Rawat, Shi, Hoffman: Early onset of inflammation and later involvement of TGFbeta in Duchenne muscular dystrophy. in Neurology 2005
Show all 12 Pubmed References
Human Polyclonal TLR7 Primary Antibody for FACS - ABIN4360345
Lee, Wu, Lee, Chuang, Katakura, Liu, Chan, Tawatao, Chung, Shen, Cottam, Lai, Raz, Carson: Activation of anti-hepatitis C virus responses via Toll-like receptor 7. in Proceedings of the National Academy of Sciences of the United States of America 2006
Show all 11 Pubmed References
Human Polyclonal TLR7 Primary Antibody for FACS - ABIN4360344
Wong, Cheung, Ip, Lam: Intracellular signaling mechanisms regulating toll-like receptor-mediated activation of eosinophils. in American journal of respiratory cell and molecular biology 2007
Show all 10 Pubmed References
Human Monoclonal TLR7 Primary Antibody for CyTOF, FACS - ABIN4360357
Lehmann, Krüger, Park, Derkow, Rosenberger, Baumgart, Trimbuch, Eom, Hinz, Kaul, Habbel, Kälin, Franzoni, Rybak, Nguyen, Veh, Ninnemann, Peters, Nitsch, Heppner, Golenbock, Schott, Ploegh, Wulczyn et al.: An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration. ... in Nature neuroscience 2012
Show all 4 Pubmed References
Human Monoclonal TLR7 Primary Antibody for FACS - ABIN4897510
Ma, Ni, Zhang, Zhang, Wu, Atia, Thayer, Moorman, Yao: PD-1 negatively regulates interleukin-12 expression by limiting STAT-1 phosphorylation in monocytes/macrophages during chronic hepatitis C virus infection. in Immunology 2011
Show all 3 Pubmed References
Human Monoclonal TLR7 Primary Antibody for CyTOF, FACS - ABIN4360354
Chauhan, Singh, Rai, Rai, Rai: Distinct autoantibody profiles in systemic lupus erythematosus patients are selectively associated with TLR7 and TLR9 upregulation. in Journal of clinical immunology 2013
Show all 3 Pubmed References
Human Polyclonal TLR7 Primary Antibody for IHC (p), WB - ABIN4360334
Tengroth, Millrud, Kvarnhammar, Kumlien Georén, Latif, Cardell: Functional effects of Toll-like receptor (TLR)3, 7, 9, RIG-I and MDA-5 stimulation in nasal epithelial cells. in PLoS ONE 2014
Show all 3 Pubmed References
Study evaluated innate immune profiles following TLR stimulation in HIV-1-infected mothers and newborns, found significantly compromised cytokine responses upon extracellular and intracellular TLR activation. Myeloid dendritic cell (DC) responsiveness appeared to be less impaired than plasmacytoid DCs, and might be enhanced through TLR7/TLR8 (show TLR8 Antibodies) activation.
This is the first study illustrating certain genotypes of TLR-7 and TLR-8 (show TLR8 Antibodies) single nucleotide polymorphisms viz. CT(p = 0.002)]; rs3853839[GC(p < 0.001), CC(p = 0.039)] and rs3764879[GC(p < 0.001)] were considerably associated with Chikungunya virus susceptibility.
study demonstrates that activation of TLR7 signaling in T cells can inhibit Th17 cell differentiation from naive T cells and IL-17 (show IL17A Antibodies) production in established Th17 cells; further report that downregulation of STAT3 (show STAT3 Antibodies) signaling is responsible for TLR7-mediated inhibition of Th17 cells due to induction of suppressor of cytokine signaling 3 (show SOCS3 Antibodies) and 5
Data indicate a mechanism in which Toll (show TLR4 Antibodies)-like receptors TLR7/8 signaling, through shedding of FcgRIIA, shifts neutrophil function from phagocytosis to a programmed necrosis pathway, neutrophil extracellular trap formation (NETosis).
TLR7 is abundantly expressed in human atherosclerotic plaques. TLR7 ligation elicits the secretion of pro-inflammatory and anti-inflammatory cytokines, and high TLR7 expression in plaques is associated with better patient outcome.
this study identified TLR7 as mediator of monocyte differentiation and M2 macrophage polarization during hepatitis C virus infection
Increased susceptibility to autoimmune is associated with single nucleotide polymorphisms and copy number variations of Toll like receptor 7. [review]
COPD (show ARCN1 Antibodies) lung tissue explants showed a greater pro-inflammatory response to TLR3 (show TLR3 Antibodies) or TLR7/8 activation than control smokers.
combination adjuvant systems demonstrate markedly different immune activation with age, with combined DC activation via Macrophage-inducible C-type lectin (show CLEC4E Antibodies) and TLR7/8 representing a novel approach to enhance the efficacy of early-life vaccines.
the activation of TLR7 increased CCND3 (show CCND3 Antibodies) expression via the downregulation of miR (show MLXIP Antibodies)-15b in B cells.
these data demonstrate that extracellular-miRNA mimics (miR (show MLXIP Antibodies)-34a, -122, -133a, -142, -146a, and -208a) are potent innate immune activators and that the miRNAs most likely induce cytokine production and leukocyte migration through TLR7 signaling
Notch1-Hes-1 signaling controls TLR7-induced autophagic death of macrophage via regulation of P62 in mice with lupus.
Dual TLR2 (show TLR2 Antibodies)/TLR7 agonist induced the maturation of dendritic cells and primed substantial populations of cytolytic and highly polyfunctional effector CD8 (show CD8A Antibodies)(+) T cells in vitro, and safely potentiated the immunogenic properties of a nanoparticulate Ag in vivo, eliciting humoral responses with a balanced TH1 (show HAND1 Antibodies)/TH2 profile in mice.
determine the effects of a loss of autophagy in dendritic cells (DCs), as well as both B cells and DCs, in a TLR7-mediated model of autoimmunity, similar to systemic lupus erythematosus, where both cell types are critical for disease
findings show that TLR7 activation significantly promoted interphotoreceptor retinoid-binding protein (IRBP (show RBP3 Antibodies))-specific Th17 responses by upregulating RORgammat, IL-17 (show IL17A Antibodies), GM-CSF (show CSF2 Antibodies), and IL-23R (show IL23R Antibodies) expression in experimental autoimmune uveitis mice.
CD72 (show CD72 Antibodies) appears to specifically inhibit B cell response to the endogenous TLR7 ligand Sm/RNP (show RNPC3 Antibodies).
TLR8 (show TLR8 Antibodies) coupling with SOCS-1 (show SOCS1 Antibodies) inhibits TLR7-mediated antiviral immunity during WNV infection in mice.
Azithromycin impairs imiquimod-induced dendritic cell activation by decreasing lysosomal acidification and disrupting TLR7 maturation and signaling.
TLR7 stimulation of Bovine Viral Diarrhea Virus Type 2-infected monocyte-derived macrophages induced cytokine secretion, unlike results observed for other Toll (show TLR4 Antibodies)-Like Receptors.
The results from this study demonstrate that expression of at least TLR3 (show TLR3 Antibodies), TLR7 and TLR8 (show TLR8 Antibodies) is stimulated upon bovine alpha-herpesvirus infection of the brain.
expression of TLR3 (show TLR3 Antibodies), TLR7 and TLR9 (show TLR9 Antibodies) in alveolar macrophages infected with different genotype 1 PRRSV strains
Porcine TLR7 and TLR8 (show TLR8 Antibodies) genes from pig lymph node tissue, were cloned and characterized.
The messenger RNA sequences and exon/intron structures of Toll (show TLR4 Antibodies)-like receptors 3, 7, and 8 were determined.
A total of 22 polymorphic sites were observed in TLR7 gene of 24 goats representing 12 different breeds, out of which 19 were present within the coding region and three in 3'UTR (show UTS2R Antibodies).
Activation of Toll-like receptor 7 might prevent development of airway hyperresponsiveness by acting on the airway smooth muscle.
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X.
toll-like receptor 7
, toll-like receptor 7-like
, toll like receptor 7
, toll-like receptor 7-long