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Browse our TLR9 Proteins (TLR9)

Full name:
Toll-Like Receptor 9 Proteins (TLR9)
On are 12 Toll-Like Receptor 9 (TLR9) Proteins from 4 different suppliers available. Additionally we are shipping TLR9 Antibodies (315) and TLR9 Kits (47) and many more products for this protein. A total of 384 TLR9 products are currently listed.
list all proteins Gene Name GeneID UniProt
TLR9 54106 Q9NR96
TLR9 81897 Q9EQU3
TLR9 338457  

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TLR9 Proteins (TLR9) by Origin

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Top referenced TLR9 Proteins

  1. Human TLR9 Protein expressed in Wheat germ - ABIN1330558 : Julian, Shao, Vangundy, Papenfuss, Crouser: Mitochondrial transcription factor A, an endogenous danger signal, promotes TNF? release via RAGE- and TLR9-responsive plasmacytoid dendritic cells. in PLoS ONE 2013 (PubMed)

More Proteins for TLR9 Interaction Partners

Human Toll-Like Receptor 9 (TLR9) interaction partners

  1. this study shows that that newborn naiive B cells express more TLR9 than adult B cells

  2. TLR9 ligands may contribute to the immunopathogenesis of sarcoidosis via induction of CXCL10 (show CXCL10 Proteins) release in the alveolar macrophages.

  3. The difference in TLR9 expression are involved in pathogenesis of the Systemic Lupus Erythematosus, hence it can be used as an indicator for Systemic Lupus Erythematosus diagnosis.

  4. TLR9 regulates melanogenesis through NF-kappaB (show NFKB1 Proteins) activation, suggesting that TLR9 may play a role in microbial-induced melanogenesis.

  5. mitochondrial DNA and TLR9 as the cargo and the receptor that triggers and mediates a lysosomal response to the arrival of autophagosomal cargo

  6. TLR9 upregulation in cases with episomal HPV16 was again higher among those with non-methylated immunostimulatory CpG motifs. Comparison of cases with HPV-negative controls revealed that DNMT3A (show DNMT3A Proteins) was significantly downregulated only among integrated cases, DNMT3B (show DNMT3B Proteins) was significantly overexpressed among both categories of cases, although at variable levels, while DNMT1 (show DNMT1 Proteins) failed to show any deregulated expression among the cases

  7. CPG-ODNs have inhibitory effects on S. aureus survival inside SAOS-2 osteoblast-like cell line. This effect was attributed to stimulation of TLR9 and subsequent induction of oxidative stress. Pretreatment of infected SAOS-2 cells with ROS (show ROS1 Proteins) inhibitors resulted in the abolishment of the CPG-ODNs killing effects.

  8. Results suggest a potential role for the host genetic background in diabetes mellitus type 2 diabetic foot susceptibility and demonstrate that there is an association between TLR9-1237 T/C polymorphism and the risk of diabetic foot, but no association was found with TLR2

  9. TLR9 induction can affect lung function by inactivating PTP1B (show PTPN1 Proteins) and upregulating expression of proinflammatory cytokines.

  10. TLR9 may be promptly induced and recruit autophagy components from the endosome to autophagosome in response to stress.

Mouse (Murine) Toll-Like Receptor 9 (TLR9) interaction partners

  1. The mRNA expression of TLR4 (show TLR4 Proteins) and NF-kappaB (show NFKB1 Proteins) is decreased in a neonatal murine model of necrotizing enterocolitis.

  2. Although the TLR9 signaling pathway is not involved in the acute inflammatory response in infarct hearts, it ameliorates cardiac rupture possibly by promoting proliferation and differentiation of cardiac fibroblasts.

  3. loss of Tlr9 selectively augments the intensity of IL-17 (show IL17A Proteins)-driven immune responses to H. pylori in a cag T4SS-dependent manner.

  4. functional Tlr9 signaling in neutrophils, is an important mechanism in early stasis experimental venous thrombogenesis.

  5. this paper shows that endosomal retention of TLR9 via the interaction of IRAP (show IL1RN Proteins) with the actin cytoskeleton is a mechanism that prevents hyper-activation of TLR9 in dendritic cells

  6. data demonstrated for the first time that NK cells directly recognize Baculovirus via TLR9, which provides opportunities for the use of this technique as an effective tool for Baculovirus-based immunotherapies against malignancies.

  7. 3-Hydroxy-4,7-megastigmadien-9-one, isolated from Ulva pertusa, attenuates TLR9-mediated inflammatory response by down-regulating mitogen-activated protein kinase (show MAPK1 Proteins) and NF-kappaB (show NFKB1 Proteins) pathways.

  8. Results demonstrate that nerve stimulation of TLR9 knock-out muscles produces weaker response than when the muscle is stimulated directly; TLR9 knock-out mice have functional and morphological alterations of the neuromuscular junction

  9. Munc13-4 (show UNC13D Proteins) regulates endosome-initiated, TLR9-dependent signaling and TLR9-specific cellular functions in neutrophils.

  10. TLR9 expression showed dynamic changes for a long period of time and microglias were the main brain cells to express TLR9 after cerebral ischemia and reperfusion.

Pig (Porcine) Toll-Like Receptor 9 (TLR9) interaction partners

  1. TLR9 immunoreactivity is mainly detected in epithelial cells and antigen presenting cells, namely dendritic and macrophage-like cells, within the range of tissues examined. The pattern of TLR9 expression was similar in pigs of 3 weeks and 3 months of age.

  2. These data demonstrated that TLR2, TLR3 (show TLR3 Proteins) and TLR9 contribute to NF-kappaB (show NFKB1 Proteins) activation in response to porcine epidemic diarrhea virus infection, but not RIG-I (show DDX58 Proteins).

  3. expression of TLR3 (show TLR3 Proteins), TLR7 (show TLR7 Proteins) and TLR9 in alveolar macrophages infected with different genotype 1 PRRSV strains

  4. we studied TLR9 expression in lung extracts from pigs, dogs, and cattle.

  5. Moreover, the TLR9 transfectant demonstrated its usefulness for evaluation of immunostimulation by bacterial DNA through the detection of T(H)-1, T(H)-2 type cytokine induction via TLR9 signaling.

Cow (Bovine) Toll-Like Receptor 9 (TLR9) interaction partners

  1. variants in the TLR1 (show TLR1 Proteins) gene are associated with susceptibility to bovine tuberculosis, whereas no significant association can be inferred from the polymorphisms in the TLR9 gene

  2. we studied TLR9 expression in lung extracts from pigs, dogs, and cattle.

  3. mRNA abundances of TLR9, TLR2, and TLR4 together with those of beta-defensin 5 (BNBD5), an early bactericidal effector molecule of the innate system, in healthy and infected mammary glands

  4. substantial conservation of TLR9 structure and TLR9 function in blood leukocytes

TLR9 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.

Alternative names and synonyms associated with TLR9

  • toll-like receptor 9 (TLR9)
  • toll-like receptor 9 (Tlr9)
  • CD289 protein

Protein level used designations for Toll-Like Receptor 9 Proteins (TLR9)

Toll-like receptor 9 protein

54106 Homo sapiens
81897 Mus musculus
338457 Rattus norvegicus
397007 Sus scrofa
282602 Bos taurus
403502 Canis lupus familiaris
493839 Felis catus
494547 Ovis aries
100860819 Capra hircus
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