Browse our EEA1 Proteins (EEA1)

Full name:
Early Endosome Antigen 1 Proteins (EEA1)
On are 5 Early Endosome Antigen 1 (EEA1) Proteins from 4 different suppliers available. Additionally we are shipping EEA1 Antibodies (126) and EEA1 Kits (7) and many more products for this protein. A total of 145 EEA1 products are currently listed.
A430109M19Rik, B230358H09Rik, im:7151048, LOC562732, MST105, MSTP105, si:ch211-276p10.2, ZFYVE2
list all proteins Gene Name GeneID UniProt
EEA1 8411 Q15075
EEA1 216238 Q8BL66
Rat EEA1 EEA1 314764  

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EEA1 Proteins (EEA1) by Origin

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Human Early Endosome Antigen 1 (EEA1) interaction partners

  1. results suggest a new mechanism in which Rab5 (show RAB5A Proteins) induces a change in flexibility of EEA1, generating an entropic collapse force that pulls the captured vesicle towards the target membrane to initiate docking and membrane fusion

  2. EEA1 mobility on endosomes is decreased upon stimulation of EGF receptor (show EGFR Proteins) endocytosis in HeLa cells

  3. Under the regulation of Rab5 (show RAB5A Proteins), the fused vesicles are targeted to early endosomes and thus deliver the internalized TbetaRI (show TGFBR1 Proteins) to the caveolin-1 (show CAV1 Proteins) and EEA1 double-positive early endosomes (caveolin-1 (show CAV1 Proteins)-positive early endosomes).

  4. In serum-deprivated HeLa cells with low endocytic activity there two types of EEA1-vesicles: the first one carries the both EEA1 and Rab5 (show RAB5A Proteins) at high levels; the second consists of weakly decorated EEA1-vesicles that can be both Rab5 (show RAB5A Proteins)-positive and -negative.

  5. Data indicate that early endosome antigen 1 (EEA1) is important for the small GTPase (show RACGAP1 Proteins) Rab31 (show RAB31 Proteins)-mediated enhancement of ligand-bound EGF receptor (EGFR (show EGFR Proteins)) endocytic trafficking.

  6. nuclear uptake of Abeta (show APP Proteins) involves the dynamin (show DNM1 Proteins)-dependent EEA1 and TGF-beta (show TGFB1 Proteins)/Smad (show SMAD1 Proteins) signaling pathways.

  7. We therefore propose that the N1072K variant of the EEA1 gene is a candidate mutation for susceptibility to diabetes in the Japanese population.

  8. EEA1 interacts with Phafin2 and colocolizes with Phafin2 in endosome membrane.

  9. NMR analyses of the interaction between the FYVE domain of early endosome antigen 1 (EEA1) and phosphoinositide embedded in a lipid bilayer.

  10. p97 (show EIF4G2 Proteins) inhibition causes increased EEA1 self-association at the endosome membrane.

Mouse (Murine) Early Endosome Antigen 1 (EEA1) interaction partners

  1. In the present study, decreased expression of EEA1 as well as the rearrangement of the actin was observed when Paracoccidioides brasiliensis was internalized in macrophages.

  2. Tec (show NR4A3 Proteins) vesicles have a membrane proximal location and overlap with the tyrosine kinase (show TYRO3 Proteins) Lck (show LCK Proteins), the Tec (show NR4A3 Proteins) substrate PLC-gamma1 (show PLCG1 Proteins), and the early endosomal antigen 1 marker EEA1

  3. phosphomimetic mutation of Thr (show TRH Proteins)-1392 in EEA1 can bypass the requirement for p38alpha (show MAPK14 Proteins) in mu opioid receptor (show OPRM1 Proteins) endocytosis

  4. F. tularensis-containing endosomes associated with early endosome antigen 1 (EEA1) followed by lysosome-associated membrane protein 1 (LAMP-1 (show LAMP1 Proteins)), with peak coassociation frequencies occurring at 30 and 120 min postinoculation, respectively.

EEA1 Protein Profile

Protein Summary

Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking.

Alternative names and synonyms associated with EEA1

  • early endosome antigen 1 (EEA1)
  • novel protein similar to H.sapiens EEA1, early endosome antigen 1 (EEA1) (LOC562732)
  • early endosome antigen 1 (Eea1)
  • early endosome antigen 1 (eea1)
  • A430109M19Rik protein
  • B230358H09Rik protein
  • im:7151048 protein
  • LOC562732 protein
  • MST105 protein
  • MSTP105 protein
  • si:ch211-276p10.2 protein
  • ZFYVE2 protein

Protein level used designations for EEA1

early endosome antigen 1, 162kD , novel protein similar to H.sapiens EEA1, early endosome antigen 1 (EEA1) , early endosome-associated protein , endosome-associated protein p162 , zinc finger FYVE domain-containing protein 2

467212 Pan troglodytes
562732 Danio rerio
8411 Homo sapiens
475424 Canis lupus familiaris
216238 Mus musculus
314764 Rattus norvegicus
492695 Danio rerio
414564 Xenopus laevis
417896 Gallus gallus
516259 Bos taurus
101088764 Felis catus
100064347 Equus caballus
100153403 Sus scrofa
101114003 Ovis aries
100727802 Cavia porcellus
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