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Data show that in the MCF-7 breast cancer cell line, only MT1X metallothioneins (MTs (show TIMM8A Proteins)) positively correlated with vascular endothelial growth factor C (VEGFC (show VEGFC Proteins)).
These findings suggest that functional interactions between FHL3 (show FHL3 Proteins) and MT-1X may provide some clues to the mechanisms of FHL3 (show FHL3 Proteins)-regulated cell proliferation.
Results show variation in MTX1 (show MTX1 Proteins) is implicated in disordered gambling
siRNA-mediated knockdown of TCRP1 and MT1X was found to sensitize cells to cisplatin, leading to increased apoptosis and inhibition of cell proliferation
Our results suggest that MT1XT20 represents a sensitive and specific marker for MSI (show MSI1 Proteins) testing and could be included in a complete set of MSI (show MSI1 Proteins) markers for the confident identification of familial or sporadic dMMR patients in colorectal cancers.
MT-1A (show MT1A Proteins), -1F, -1G, -1X and -2A isoforms are significantly down-regulated in proliferating keloid fibroblasts.
Metallothioneins have a high content of cysteine residues that bind various heavy metals\; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
, metallothionein 1A (functional)
, metallothionein 1E (functional)
, metallothionein 1F
, metallothionein 1X
, metallothionein 1L