Browse our S100A8 Proteins (S100A8)

Full name:
S100 Calcium Binding Protein A8 Proteins (S100A8)
On www.antibodies-online.com are 43 S100 Calcium Binding Protein A8 (S100A8) Proteins from 12 different suppliers available. Additionally we are shipping S100A8 Antibodies (254) and S100A8 Kits (60) and many more products for this protein. A total of 373 S100A8 products are currently listed.
Synonyms:
60B8Ag, AI323541, B8Ag, Caga, CFAg, CGLA, CP-10, EWWD, L1Ag, MA387, MIF, Mrp8, NIF, p8, S100A8, WW
list all proteins Gene Name GeneID UniProt
S100A8 85320 Q96J66
S100A8 116547 P50115
S100A8 20201 P27005

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S100A8 Proteins (S100A8) by Origin

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Top referenced S100A8 Proteins

  1. Human S100A8 Protein expressed in Wheat germ - ABIN1319072 : Maiseyeu, Badgeley, Kampfrath, Mihai, Deiuliis, Liu, Sun, Parthasarathy, Simon, Croce, Rajagopalan: In vivo targeting of inflammation-associated myeloid-related protein 8/14 via gadolinium immunonanoparticles. in Arteriosclerosis, thrombosis, and vascular biology 2012 (PubMed)
    Show all 5 references for 1319072

  2. Mouse (Murine) S100A8 Protein expressed in Escherichia coli (E. coli) - ABIN667469 : Kerkhoff, Klempt, Sorg: Novel insights into structure and function of MRP8 (S100A8) and MRP14 (S100A9). in Biochimica et biophysica acta 1999 (PubMed)
    Show all 2 references for 667469

More Proteins for S100A8 Interaction Partners

Human S100 Calcium Binding Protein A8 (S100A8) interaction partners

  1. Data show that E3 ubiquitin ligase (show MUL1 Proteins) HRD1 (HRD1 (show SYVN1 Proteins)) decreased the protein level of S100A8 through ubiquitination.

  2. High S100A8 expression is associated with glioblastoma.

  3. This study implicates S100A8 and S100A9 (show S100A9 Proteins) as important mediators of tumor cell aggressiveness, and highlights the therapeutic potential of S100A8 and S100A9 (show S100A9 Proteins) for interference of metastasis.

  4. Data indicate a statistical correlation between fecal calprotectin (FC) and gastrointestinal graft-versus-host disease (GvHD).

  5. Perinatal alarmins S100A8 and S100A9 (show S100A9 Proteins) specifically altered MyD88 (show MYD88 Proteins)-dependent proinflammatory gene programs. S100 programming prevented hyperinflammatory responses without impairing pathogen defense. TRIF (show TRIM69 Proteins)-adaptor-dependent regulatory genes remained unaffected by perinatal S100 programming and responded strongly to lipopolysaccharide, but were barely expressed.

  6. Expression of S100A8, S100A9 (show S100A9 Proteins) and S100A12 (show S100A12 Proteins) is modulated by eicosapentaenoic acid and docosahexaenoic acid during Inflammation in adipose tissue and mononuclear cells.

  7. High S100A8 expression is associated with lung metastasis in malignant melanoma.

  8. Data show that the standardized nerve growth factor (NGF) concentration was negatively correlated with continuous pain, neuropathic pain and total score, and the standardized S100 proteins S100A8/A9 concentration was positively correlated with present pain intensity and continuous pain.

  9. S100A8 and S100A9 (show S100A9 Proteins) proteins in concentrations secreted by CD34 (show CD34 Proteins)(-)/CD31 (show HBA1 Proteins)(+) circulating angiogenic cells (CACs) with impaired function reduce endothelial cell capillary-like network formation. These effects appear to be mediated by Toll-like receptor 4 (show TLR4 Proteins) and are absent with S100A8 and S100A9 (show S100A9 Proteins) in concentrations secreted by healthy CD34 (show CD34 Proteins)(-)/CD31 (show HBA1 Proteins)(+) CACs.

  10. The present study shows that the protein expression of ABCC10 (show ABCC10 Proteins) significantly associates with overall survival and the expression of ABCC11 with disease-free interval of colorectal cancer patients

Cow (Bovine) S100 Calcium Binding Protein A8 (S100A8) interaction partners

  1. Data suggest that up-regulation of S100A8 and S100A9 (show S100A9 Proteins) is a key component of early endometrial response to uterine involution in the post-partum period and to prevent chronic endometritis/uterine inflammation; up-regulation can be influenced by diet.

Pig (Porcine) S100 Calcium Binding Protein A8 (S100A8) interaction partners

  1. Study verified porcine calprotectin (S100A8/A9) expression at the protein level in multiple Haemophilus parasuis infected tissues and explored their molecular characterization.

Mouse (Murine) S100 Calcium Binding Protein A8 (S100A8) interaction partners

  1. Neutrophil-derived S100A8/A9 promotes thrombocytosis in diabetic mice

  2. Perinatal alarmins S100A8 and S100A9 (show S100A9 Proteins) specifically altered MyD88 (show MYD88 Proteins)-dependent proinflammatory gene programs. S100 programming prevented hyperinflammatory responses without impairing pathogen defense. TRIF (show RNF138 Proteins)-adaptor-dependent regulatory genes remained unaffected by perinatal S100 programming and responded strongly to lipopolysaccharide, but were barely expressed.

  3. S100a8 upregulation triggers NF-kappaB (show NFKB1 Proteins) signal pathway through RAGE (show AGER Proteins) and TLR4 (show TLR4 Proteins), in response to laser-induced dermis wound healing.

  4. Although MRP-8/-14 expression is highly increased in experimental, these proteins do not contribute to the pathogenesis in the effector phase of epidermolysis bullosa acquisita and bullous pemphigoid (show DST Proteins).

  5. TLR4 (show TLR4 Proteins), TLR2 also contributed to Mrp8-induced inflammatory response and tolerance.

  6. S100A8 appears to play a crucial role in the activation of the TLR4 (show TLR4 Proteins)/MD-2 (show LY96 Proteins) pathway and the promotion of a tumor growth-enhancing immune microenvironment.

  7. Rps14 (show RPS14 Proteins) haploinsufficiency in del(5q) myelodysplastic syndrome is linked to activation of the innate immune system and induction of S100A8-S100A9 (show S100A9 Proteins) expression, leading to a p53 (show TP53 Proteins)-dependent erythroid differentiation defect.

  8. S100A8 is primarily produced from CXCR2 (show CXCR2 Proteins)-expressing CD11b (show ITGAM Proteins)(+)Gr-1 (show GSR Proteins)(high) cells, and it upregulates TNF-alpha (show TNF Proteins) production in CD11b (show ITGAM Proteins)(+)F4/80(+) cells through cellular cross-talk, which is an important mechanism in the development of Nonalcoholic fatty liver disease

  9. Alarmins S100A8/S100A9 (show S100A9 Proteins) aggravate osteophyte formation in experimental osteoarthritis and predict osteophyte progression in early human symptomatic osteoarthritis.

  10. This study identified Mrp8/14 and TLR4 (show TLR4 Proteins) as important modulators of the leukocyte recruitment cascade during inflammation via integrin beta2.

S100A8 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis.

Alternative names and synonyms associated with S100A8

  • ATP-binding cassette, sub-family C (CFTR/MRP), member 11 (ABCC11)
  • S100 calcium binding protein A8 (S100A8)
  • S100 calcium binding protein A8 (S100a8)
  • S100 calcium binding protein A8 (calgranulin A) (S100a8)
  • 60B8Ag protein
  • AI323541 protein
  • B8Ag protein
  • Caga protein
  • CFAg protein
  • CGLA protein
  • CP-10 protein
  • EWWD protein
  • L1Ag protein
  • MA387 protein
  • MIF protein
  • Mrp8 protein
  • NIF protein
  • p8 protein
  • S100A8 protein
  • WW protein

Protein level used designations for S100A8

ATP-binding cassette protein C11 , ATP-binding cassette sub-family C member 11 , ATP-binding cassette transporter MRP8 , ATP-binding cassette transporter sub-family C member 11 , multi-resistance protein 8 , multidrug resistance-associated protein 8 , MRP-8 , S100 calcium-binding protein A8 (calgranulin A) , calgranulin A , calgranulin-A , calprotectin L1L subunit , cystic fibrosis antigen , leukocyte L1 complex light chain , migration inhibitory factor-related protein 8 , protein S100-A8 , urinary stone protein band A , S100 calcium binding protein A8 (calgranulin A) , p8 , S100 calcium binding protein A8 , BEE11 , P7 , S100 calcium-binding protein A8 , neutrophil cytosolic 7 kDa protein , calprotectin , chemotactic S100 protein , chemotactic cytokine CP-10 , pro-inflammatory S100 cytokine

GENE ID SPECIES
85320 Homo sapiens
6279 Homo sapiens
116547 Rattus norvegicus
457319 Pan troglodytes
490461 Canis lupus familiaris
616818 Bos taurus
714740 Macaca mulatta
100127488 Sus scrofa
100294529 Equus caballus
20201 Mus musculus
100735514 Cavia porcellus
101104026 Ovis aries
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