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Browse our anti-KDM6A (KDM6A) Antibodies

Full name:
anti-Lysine (K)-Specific Demethylase 6A Antibodies (KDM6A)
On www.antibodies-online.com are 27 Lysine (K)-Specific Demethylase 6A (KDM6A) Antibodies from 10 different suppliers available. Additionally we are shipping KDM6A Proteins (5) and many more products for this protein. A total of 38 KDM6A products are currently listed.
Synonyms:
bA386N14.2, KABUK2, RGD1565481, Utx, Uty
list all antibodies Gene Name GeneID UniProt
KDM6A 7403 O15550
KDM6A 22289 O70546
KDM6A 100310845  

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anti-Human KDM6A Antibodies:

anti-Mouse (Murine) KDM6A Antibodies:

anti-Rat (Rattus) KDM6A Antibodies:

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Top referenced anti-KDM6A Antibodies

  1. Dog (Canine) Polyclonal KDM6A Primary Antibody for WB - ABIN2781142 : Hong, Cho, Yu, Yu, Veenstra, Ge: Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases. in Proceedings of the National Academy of Sciences of the United States of America 2007 (PubMed)

More Antibodies against KDM6A Interaction Partners

Human Lysine (K)-Specific Demethylase 6A (KDM6A) interaction partners

  1. UTX gene expression in renal cell carcinoma (show MOK Antibodies) and bladder cancer.

  2. Mutations of the epigenetic genes KMT2D (show MLL2 Antibodies) and KDM6A cause dysregulation of certain developmental genes and account for the multiple congenital anomalies of the syndrome

  3. UTX positively regulates E-cadherin (show CDH1 Antibodies) expression in colon cancer cells.

  4. UTX is a prominent tumour suppressor that functions as a negative regulator of EMT (show ITK Antibodies)-induced Cancer Stem Cell-like properties by epigenetically repressing epithelial-mesenchymal transition -TFs.

  5. Kabuki syndrome may be caused by mutations in one of two histone methyltransferase genes: KMT2D (show MLL2 Antibodies) and KDM6A.

  6. Our results provide further support for the similar roles of KMT2D (show MLL2 Antibodies) and KDM6A in the etiology of KS by using a vertebrate model organism to provide direct evidence of their roles in the development of organs and tissues affected in KS patients.

  7. Turner Syndrome subjects, who are predisposed to chronic ear infections, had reduced UTX expression in immune cells and decreased circulating CD4(+) CXCR5(+) T cell frequency.

  8. A report of novel KDM6A mutations in patients with Kabuki syndrome.

  9. The KDM6A gene is a histone demethylase (show MBD2 Antibodies) specific for histone H3 (show HIST3H3 Antibodies) Lysin 27 and regulates gene transcription [35]. In approximately 24% of urothelial carcinoma, KDM6A is altered.

  10. This study is the first to identify frequent BAP1 (show RNF2 Antibodies) and BRCA pathway alterations in bladder cancer, show TERT (show TERT Antibodies) promoter alterations are independent of other bladder cancer gene alterations, and show KDM6A loss is a driver of the bladder cancer phenotype.

Mouse (Murine) Lysine (K)-Specific Demethylase 6A (KDM6A) interaction partners

  1. differentiating embryonic stem cells (ESCs (show NR2E3 Antibodies)) depend on KDM6 and the H3K27me3 demethylase (show MBD2 Antibodies) activity is crucially involved in DNA damage response and survival of differentiating ESCs (show NR2E3 Antibodies).

  2. a critical role for the enzymatic activity of UTX in activating muscle-specific (show EIF3K Antibodies) gene expression during myofiber regeneration and have revealed a physiological role for active H3K27 demethylation in vivo.

  3. Results propose that Utx plays important roles in osteoblast differentiation by controlling the expressions of Runx2 (show RUNX2 Antibodies) and Osterix (show SP7 Antibodies).

  4. Utx is required for T-cell development.

  5. Genome-wide association between Six4 (show SIX4 Antibodies), MyoD (show MYOD1 Antibodies), and the histone demethylase Utx during myogenesis.

  6. Mice with a T-cell-specific UTX deletion had fewer Tfh cells, reduced germinal center responses, no virus-specific IgG, inability to resolve chronic LCMV infections, and decreased expression of IL-6-receptor-alpha (show IL6R Antibodies) and other Tfh cell-related genes.

  7. UTX may play a potential role in regulation of brown adipocyte gene expression

  8. Utx and Jmjd3 (show Kdm6b Antibodies) mutant mouse embryonic fibroblasts (MEFs) demonstrate dramatic loss of H3K27me3 from promoters of several Hox (show MSH2 Antibodies) genes and transcription factors.

  9. Inhibition of histone demethylases UTX and JMJD3 (show Kdm6b Antibodies) inhibits HSV-1 reactivation from sensory neurons.

  10. H3K27me3 demethylase (show MBD2 Antibodies) UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia

KDM6A Antigen Profile

Antigen Summary

This gene is located on the X chromosome and is the corresponding locus to a Y-linked gene which encodes a tetratricopeptide repeat (TPR) protein. The encoded protein of this gene contains a JmjC-domain and catalyzes the demethylation of tri/dimethylated histone H3.

Alternative names and synonyms associated with KDM6A

  • lysine (K)-specific demethylase 6A (KDM6A) antibody
  • lysine (K)-specific demethylase 6A (Kdm6a) antibody
  • bA386N14.2 antibody
  • KABUK2 antibody
  • RGD1565481 antibody
  • Utx antibody
  • Uty antibody

Protein level used designations for KDM6A

lysine (K)-specific demethylase 6A , bA386N14.2 (ubiquitously transcribed X chromosome tetratricopeptide repeat protein (UTX)) , histone demethylase UTX , lysine-specific demethylase 6A , ubiquitously transcribed tetratricopeptide repeat protein X-linked , ubiquitously-transcribed TPR gene on the X chromosome , ubiquitously-transcribed TPR protein on the X chromosome , ubiquitously transcribed tetratricopeptide repeat, X chromosome , 4lysine (K)-specific demethylase 6A , ubiquitously transcribed TPR protein on the X chromosome , ubiquitously transcribed X chromosome tetratricopeptide repeat protein , ubiquitously transcribed tetratricopeptide repeat gene, X chromosome , ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome

GENE ID SPECIES
100081798 Ornithorhynchus anatinus
100539898 Meleagris gallopavo
100592229 Nomascus leucogenys
7403 Homo sapiens
491845 Canis lupus familiaris
22289 Mus musculus
100310845 Rattus norvegicus
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