Browse our anti-Lipoic Acid Synthetase (LIAS) Antibodies

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anti-Lipoic Acid Synthetase Antibodies (LIAS)
On are 26 Lipoic Acid Synthetase (LIAS) Antibodies from 11 different suppliers available. Additionally we are shipping Lipoic Acid Synthetase Proteins (14) and Lipoic Acid Synthetase Kits (4) and many more products for this protein. A total of 47 Lipoic Acid Synthetase products are currently listed.
7a5ex, 2900022L22Rik, 4933425M12Rik, C77512, LAS, Lip-syn, LIP1, LS, mLip1, PDHLD, zgc:66080

Most Popular Reactivities for anti-Lipoic Acid Synthetase (LIAS) Antibodies

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Top referenced anti-Lipoic Acid Synthetase Antibodies

  1. Cow (Bovine) Polyclonal LIAS Primary Antibody for WB - ABIN2783475 : Morikawa, Yasuno, Wada: Do mammalian cells synthesize lipoic acid? Identification of a mouse cDNA encoding a lipoic acid synthase located in mitochondria. in FEBS letters 2001 (PubMed)

More Antibodies against Lipoic Acid Synthetase Interaction Partners

Human Lipoic Acid Synthetase (LIAS) interaction partners

  1. oxoglutarate dehydrogenase (OGDH (show alphaKGDHC Antibodies)) and lipoic acid synthase (LIAS), which when mutated stabilize HIF1alpha (show HIF1A Antibodies) in a non-hydroxylated form.

  2. heterozygous mutations (c.738-2A>G and c.929T>C (p.Met310Thr)) in LIAS.

  3. Patients with LIAS nonketotic hyperglycinemia varied in disease severity and cortical involvement.

  4. We identified the homozygous mutation c.746G>A (p.Arg249His) in LIAS in an individual with neonatal-onset epilepsy, muscular hypotonia, lactic acidosis, and elevated glycine concentration in plasma and urine

  5. Lipoic acid synthetase deficiency results in an overall disturbance in the antioxidant defense network, leading to increased inflammation, insulin (show INS Antibodies) resistance, and mitochondrial dysfunction.

Mouse (Murine) Lipoic Acid Synthetase (LIAS) interaction partners

  1. Decreased endogenous lipoic acid gene expression plays a role in development of diabetic atherosclerosis in ApoE (show APOE Antibodies) deficient mice.

  2. Lias deficiency enhances atherosclerosis in male mice, at least in part due to reduced antioxidant capacity

  3. Development of homozygous embryos lacking Lias is retarded.

  4. Enhanced neutrophil sequestration in the livers of Lias+/- mice was associated with increased hepatocyte injury and increased gene expression of growth-related oncogene (show RAB1A Antibodies), E-selectin (show SELE Antibodies), and VCAM-1 (show VCAM1 Antibodies) in the liver and/or lung.

Lipoic Acid Synthetase (LIAS) Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the biotin and lipoic acid synthetases family. It localizes in mitochondrion and plays an important role in alpha-(+)-lipoic acid synthesis. It may also function in the sulfur insertion chemistry in lipoate biosynthesis. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.

Alternative names and synonyms associated with Lipoic Acid Synthetase (LIAS)

  • lipoic acid synthetase (AaeL_AAEL009368) antibody
  • lipoic acid synthetase (THAPSDRAFT_31845) antibody
  • lipoic acid synthetase (THAPSDRAFT_31673) antibody
  • lipoic acid synthetase (UREG_00501) antibody
  • lipoic acid synthetase (LOAG_04019) antibody
  • lipoic acid synthetase (TERG_02451) antibody
  • lipoic acid synthetase (Tsp_01534) antibody
  • lipoic acid synthetase (LIAS) antibody
  • lipoic acid synthetase (Lias) antibody
  • lipoic acid synthetase (lias) antibody
  • LOC100279807 (umc2251) antibody
  • 7a5ex antibody
  • 2900022L22Rik antibody
  • 4933425M12Rik antibody
  • C77512 antibody
  • LAS antibody
  • Lip-syn antibody
  • LIP1 antibody
  • LS antibody
  • mLip1 antibody
  • PDHLD antibody
  • zgc:66080 antibody

Protein level used designations for LIAS

lipoic acid synthetase , lip-syn , lipoate synthase , lipoyl synthase, mitochondrial , LS , lipoic acid synthase , Lipoate synthase , Lipoic acid synthase , PCO124891 , PCO124891_ov , p-umc2251

5571879 Aedes aegypti
7452159 Thalassiosira pseudonana CCMP1335
7453454 Thalassiosira pseudonana CCMP1335
8437299 Uncinocarpus reesii 1704
9941423 Loa loa
10379120 Trichophyton rubrum CBS 118892
10911601 Trichinella spiralis
11019 Homo sapiens
79464 Mus musculus
305348 Rattus norvegicus
393528 Danio rerio
443960 Xenopus laevis
479108 Canis lupus familiaris
530865 Bos taurus
100279807 Zea mays
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