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Human Monoclonal NAPSA Primary Antibody for IHC (p), IHC - ABIN259020
Hirano, Auer, Maeda, Hagiwara, Okada, Ohira, Okuzawa, Fujioka, Franzén, Hibi, Seito, Ebihara, Kato: Human tissue distribution of TA02, which is homologous with a new type of aspartic proteinase, napsin A. in Japanese journal of cancer research : Gann 2000
Show all 2 Pubmed References
Human Polyclonal NAPSA Primary Antibody for ELISA - ABIN449545
Lu, Lin, Huang, Kang, Rich, Lo, Myszka, Han, Wu: XIAP induces NF-kappaB activation via the BIR1/TAB1 interaction and BIR1 dimerization. in Molecular cell 2007
Human Monoclonal NAPSA Primary Antibody for IHC, ELISA - ABIN1724854
Aikawa, Kawahara, Hattori, Yamaguchi, Abe, Taira, Azuma, Kage: Comparison of the expression levels of napsin A, thyroid transcription factor-1, and p63 in nonsmall cell lung cancer using cytocentrifuged bronchial brushings. in Cancer cytopathology 2011
Fruit Fly (Drosophila melanogaster) Polyclonal NAPSA Primary Antibody for WB - ABIN2668697
Kimura: The Nap family proteins, CG5017/Hanabi and Nap1, are essential for Drosophila spermiogenesis. in FEBS letters 2013
Dog (Canine) Polyclonal NAPSA Primary Antibody for ICC, IF - ABIN4337855
Mangan, Sietsema, Li, Moore, Citi, Prekeris: Cingulin and actin mediate midbody-dependent apical lumen formation during polarization of epithelial cells. in Nature communications 2016
Immunohistochemical detection of thyroid transcription factor 1 (show NKX2-1 Antibodies), Napsin A, and P40 (show IL9 Antibodies) fragment of TP63 (show TP63 Antibodies) can be used in the subclassification of non-small cell lung carcinomas.
it may be useful to combine NAPA (show NAPA Antibodies) and TTF-1 (show NKX2-1 Antibodies) for increased sensitivity in lung cancer diagnostics. There is no substantial difference between monoclonal and polyclonal p40 (show IL9 Antibodies) and between different NAPA (show NAPA Antibodies) clones, whereas there is a difference between the TTF-1 (show NKX2-1 Antibodies) clones 8G7G3/1 and SPT24
To the best of our knowledge, expression of monoclonal Napsin A in lymphomas has never been reported. ALK (show ALK Antibodies)-DLBCL should be considered in the differential diagnosis when evaluating a Napsin A-positive tumor of poorly differentiated morphology and of unknown primary
It is important for pathologists to be aware that breast carcinomas with apocrine features can express napsin A.
High Napsin A expression is associated with adenocarcinoma in non-small cell lung carcinoma.
Napsin-A, and Desmocollin-3 (show DSC2 Antibodies) were sensitive and specific markers for the diagnosis of AC and SCC (show CYP11A1 Antibodies), respectively. Both markers allowed classification of 54/60 cases into either AC or SCC (show CYP11A1 Antibodies).
napsin A is aberrantly expressed in a subset of lymphomas
CK7 (show KRT7 Antibodies), TTF-1 (show NKX2-1 Antibodies) and napsin A are predominantly expressed in primary lung adenocarcinoma patients, with CDX-2 (show CDX2 Antibodies) being inconsistently expressed.
The immunocytochemical expressions of napsin A and p40 in imprint cytology seem to be of great utility for the accurate histological differentiation of lung cancers.
Combining HNF-1beta (show HNF1B Antibodies) and napsin A may distinguish clear cell carcinoma from high-grade serous carcinoma, endometrioid adenocarcinoma and metastatic Krukenberg tumors.
The activation peptides of aspartic proteinases plays role as inhibitors of the active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The pronapsin A gene is expressed predominantly in lung and kidney. Its translation product is predicted to be a fully functional, glycosylated aspartic proteinase precursor containing an RGD motif and an additional 18 residues at its C-terminus.
, asp 4
, aspartyl protease 4
, kidney-derived aspartic protease-like protein
, pronapsin A
, NAP 1
, membrane-associated protein HEM-2
, nck-associated protein 1
, likely ortholog of H. sapiens chromosome 9 open reading frame 156 (C9orf156)
, nef-associated protein 1
, thioesterase NAP1