Browse our anti-WT1 (WT1) Antibodies

Full name:
anti-Wilms Tumor 1 Antibodies (WT1)
On www.antibodies-online.com are 283 Wilms Tumor 1 (WT1) Antibodies from 24 different suppliers available. Additionally we are shipping WT1 Kits (14) and WT1 Proteins (14) and many more products for this protein. A total of 320 WT1 products are currently listed.
Synonyms:
AWT1, CWT1, D630046I19Rik, EWS-WT1, GUD, NPHS4, si:ch211-160j6.3, WAGR, WIT-2, WT, Wt-1, wt1, WT33, XeWT1, xwt1, XWT1a, XWT1b, zgc:152697
list all antibodies Gene Name GeneID UniProt
WT1 7490 P19544
WT1 24883 P49952
WT1 22431  

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anti-Human WT1 Antibodies:

anti-Rat (Rattus) WT1 Antibodies:

anti-Mouse (Murine) WT1 Antibodies:

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Top referenced anti-WT1 Antibodies

  1. Human Polyclonal WT1 Primary Antibody for FACS, IF - ABIN655904 : Sitaram, Degerman, Ljungberg, Andersson, Oji, Sugiyama, Roos, Li: Wilms' tumour 1 can suppress hTERT gene expression and telomerase activity in clear cell renal cell carcinoma via multiple pathways. in British journal of cancer 2010 (PubMed)
    Show all 5 references for 655904

  2. Human Monoclonal WT1 Primary Antibody for WB - ABIN394194 : Rocquain, Carbuccia, Trouplin, Raynaud, Murati, Nezri, Tadrist, Olschwang, Vey, Birnbaum, Gelsi-Boyer, Mozziconacci: Combined mutations of ASXL1, CBL, FLT3, IDH1, IDH2, JAK2, KRAS, NPM1, NRAS, RUNX1, TET2 and WT1 genes in myelodysplastic syndromes and acute myeloid leukemias. in BMC cancer 2010 (PubMed)
    Show all 5 references for 394194

  3. Human Monoclonal WT1 Primary Antibody for IHC, IHC (fro) - ABIN258719 : Rauscher, Morris, Fredericks, Lopez-Guisa, Balakrishnan, Jost, Herlyn, Rodeck: Characterization of monoclonal antibodies directed to the amino-terminus of the WT1, Wilms' tumor suppressor protein. in Hybridoma 1998 (PubMed)
    Show all 4 references for 258719

  4. Human Polyclonal WT1 Primary Antibody for EIA, IF - ABIN955586 : Dohi, Ohno, Ohno, Kyo, Soma, Sugiyama, Inoue: WT1 expression correlates with angiogenesis in endometrial cancer tissue. in Anticancer research 2010 (PubMed)
    Show all 4 references for 955586

  5. Human Polyclonal WT1 Primary Antibody for FACS, WB - ABIN4899232 : Da Sacco, Lemley, Sedrakyan, Zanusso, Petrosyan, Peti-Peterdi, Burford, De Filippo, Perin: A novel source of cultured podocytes. in PLoS ONE 2013 (PubMed)
    Show all 2 references for 4899232

  6. Mouse (Murine) Polyclonal WT1 Primary Antibody for IHC, WB - ABIN3021698 : Sharma, Bowman, Madden, Rauscher, Sukumar: RNA editing in the Wilms' tumor susceptibility gene, WT1. in Genes & development 1994 (PubMed)

  7. Human Polyclonal WT1 Primary Antibody for ELISA, WB - ABIN188555 : Rao, Pham, Imam, MacLean, Murali, Furuta, Sinha-Hikim, Wilkinson: Tissue-specific RNAi reveals that WT1 expression in nurse cells controls germ cell survival and spermatogenesis. in Genes & development 2006 (PubMed)

  8. Cow (Bovine) Polyclonal WT1 Primary Antibody for IHC, WB - ABIN2780340 : Ruteshouser, Robinson, Huff: Wilms tumor genetics: mutations in WT1, WTX, and CTNNB1 account for only about one-third of tumors. in Genes, chromosomes & cancer 2008 (PubMed)

More Antibodies against WT1 Interaction Partners

Xenopus laevis Wilms Tumor 1 (WT1) interaction partners

  1. WT1 interference with Wnt (show WNT2 Antibodies) signaling represents an important mode of its action relevant to the suppression of tumor growth and guidance of development.

Human Wilms Tumor 1 (WT1) interaction partners

  1. a novel role of WT1 mutations in the deregulation of epigenetic programs in leukemic cells through its interaction with TET proteins (Review)

  2. Mutations of WT1 gene is associated with Acute myeloid leukemia (show BCL11A Antibodies).

  3. The findings of the present study indicate that all females with SRNS-FSGS (show ACTN4 Antibodies) should be screened for WT1 gene mutation to diagnose whether they have FS for possible gonadectomy.

  4. Denys-Drash syndrome associated WT1 glutamine (show GFPT1 Antibodies) 369 mutants have altered sequence-preferences in DNA binding and altered responses to epigenetic cytosine modifications.

  5. Sequence variants in NPHS4 were identified in families with CRB2 (show CRB2 Antibodies)-related syndrome.

  6. WT1 modulates Akt (show AKT1 Antibodies)/JNK (show MAPK8 Antibodies) signaling pathway mediated autophagy by controlling the expression of growth arrest-specific 1 (Gas1 (show GAS1 Antibodies)).

  7. WT1 knock-down gave a corresponding decrease in QPRT (show QPRT Antibodies) gene and protein expression. Chromatin-immunoprecipitation revealed WT1 binding to a conserved site in the first intron of the QPRT (show QPRT Antibodies) gene.

  8. WT1 helps to differentiate Wilms' tumour from other paediatric renal tumours. It may help in differentiating the two subgroups of Wilms' tumour which have distinct molecular pathogenesis and biological behaviour, however, further prospective studies are required for validation of this hypothesis.

  9. a high WT1 mutation rate was observed in this group of steroid-resistant nephrotic syndrome patients

  10. Predictive value of pretransplantation molecular minimal residual disease assessment by WT1 gene expression in FLT3 (show FLT3 Antibodies)-positive acute myeloid leukemia (show BCL11A Antibodies).

Pig (Porcine) Wilms Tumor 1 (WT1) interaction partners

  1. Sodium butyrate-induced hyperacetylation up-regulates WT1 expression in porcine kidney fibroblasts, suggesting the involvement of histone acetylation in the transcriptional modulation of WT1 in porcine kidney cells.

  2. Results indicate that WT1 plays important roles in the development of porcine preimplantation embryos, but not in oocyte maturation.

  3. WT1 is expressed in porcine fetal fibroblasts, but the levels of expression were much lower compared to porcine primary kidney fibroblasts and swine testis, and WT1 is essential for the maintenance of development and survival of porcine fetal fibroblasts

Mouse (Murine) Wilms Tumor 1 (WT1) interaction partners

  1. WT1 regulates reporter gene expression through interaction with 3' UTR (show UTS2R Antibodies)-binding sites

  2. These results indicate that Osr1 (show OSR1 Antibodies) and Wt1 act synergistically to regulate nephron endowment by controlling metanephric mesenchyme specification during early nephrogenesis.

  3. Wt1 regulates the development of FLC.

  4. WT1 stimulates IGFBP5 (show IGFBP5 Antibodies) transcription in developing murine kidney.

  5. Over expression of miR (show MLXIP Antibodies)-206 promotes podocyte injury via downregulation of WT1, which provides a new pathogenic mechanism for Focal segmental glomerulosclerosis and miR (show MLXIP Antibodies)-206 may be a potential therapeutic target.

  6. by targeting WT1, miR743a suppresses the proliferation of MM cells in vitro, and probably possesses vital functions in kidney development and kidneyassociated diseases.

  7. To test the tumorigenic potential of different cell types in the developing kidney, we used kidney progenitor-specific Cre recombinase alleles to introduce Wt1 and Ctnnb1 mutations, two alterations observed in Wilms tumor, into embryonic mouse kidney, with and without biallelic Igf2 expression, another alteration that is observed in a majority of tumors

  8. miR (show MLXIP Antibodies)-125a is a regulatory molecule that suppresses WT1 expression via a direct interaction with the 3'UTR (show UTS2R Antibodies) of WT1 mRNA and miR (show MLXIP Antibodies)-125a knockout mice induce myeloproliferative disease (MPD (show MVD Antibodies)) and urogenital abnormalities

  9. The analysis presented here demonstrates that WT1 regulates a broad set of genes, and almost 50% of the top 200 podocyte-specific genes-as defined in the GUDMAP gene expression atlas-were bound by WT1.

  10. During normal heart development, spatio-temporal differences in contribution of WT-1 and Tcf21 (show TCF21 Antibodies)-LacZ (show GLB1 Antibodies) + cells to right versus left ventricular myocardium occur parallel to myocardial thickening.

Zebrafish Wilms Tumor 1 (WT1) interaction partners

  1. While wt1a has a more fundamental and early role in pronephros development and is essential for the formation of glomerular structures, wt1b functions at later stages of nephrogenesis.

WT1 Antigen Profile

Antigen Summary

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation site upstream of and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated.

Alternative names and synonyms associated with WT1

  • Wilms tumor 1 (WT1) antibody
  • Wilms tumor 1 (wt1-a) antibody
  • Wilms tumor 1 (wt1) antibody
  • Wilms tumor 1 (LOC100346776) antibody
  • Wilms tumor protein (wt1) antibody
  • Wilms tumor 1 (wt1-b) antibody
  • Wilms tumor 1 (Wt1) antibody
  • Wilms tumor 1 homolog (Wt1) antibody
  • wilms tumor 1b (wt1b) antibody
  • AWT1 antibody
  • CWT1 antibody
  • D630046I19Rik antibody
  • EWS-WT1 antibody
  • GUD antibody
  • NPHS4 antibody
  • si:ch211-160j6.3 antibody
  • WAGR antibody
  • WIT-2 antibody
  • WT antibody
  • Wt-1 antibody
  • wt1 antibody
  • WT33 antibody
  • XeWT1 antibody
  • xwt1 antibody
  • XWT1a antibody
  • XWT1b antibody
  • zgc:152697 antibody

Protein level used designations for anti-Wilms Tumor 1 (WT1) Antibodies

Wilms tumor 1 , Wilms tumor protein homolog A , Wilms tumor protein homolog , Wilms tumor protein , amino-terminal domain of EWS , last three zinc fingers of the DNA-binding domain of WT1 , Wilm's tumor suppressor , Wilms tumor protein homolog B , Chick Wilm's tumour protein , Wilms tumor suppressor protein 1b

GENE ID SPECIES
782183 Bos taurus
280959 Bos taurus
373588 Xenopus laevis
614584 Bos taurus
696061 Macaca mulatta
737987 Pan troglodytes
100101227 Ovis aries
100216184 Xenopus (Silurana) tropicalis
100346776 Oryctolagus cuniculus
100380493 Salmo salar
7490 Homo sapiens
378664 Xenopus laevis
396139 Gallus gallus
609253 Canis lupus familiaris
397338 Sus scrofa
24883 Rattus norvegicus
22431 Mus musculus
568416 Danio rerio
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