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Browse our CAMK2A Proteins (CAMK2A)

Full name:
Calcium/calmodulin-Dependent Protein Kinase II alpha Proteins (CAMK2A)
On are 10 Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) Proteins from 6 different suppliers available. Additionally we are shipping CAMK2A Antibodies (187) and CAMK2A Kits (23) and many more products for this protein. A total of 232 CAMK2A products are currently listed.
camk2, camk2b, CAMKA, CaMKII, mKIAA0968, PK2CDD, PKCCD, R74975, zgc:112538, zgc:123320
list all proteins Gene Name GeneID UniProt
CAMK2A 12322 P11798
CAMK2A 25400 P11275

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CAMK2A Proteins (CAMK2A) by Origin

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Top referenced CAMK2A Proteins

  1. Human CAMK2A Protein expressed in Baculovirus infected Insect Cells - ABIN2003179 : Schmutz, Martin, Terry, Couronne, Grimwood, Lowry, Gordon, Scott, Xie, Huang, Hellsten, Tran-Gyamfi, She, Prabhakar, Aerts, Altherr, Bajorek, Black, Branscomb, Caoile, Challacombe, Chan, Denys et al.: The DNA sequence and comparative analysis of human chromosome 5. ... in Nature 2004 (PubMed)
    Show all 3 references for ABIN2003179

More Proteins for CAMK2A Interaction Partners

Xenopus laevis Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) interaction partners

  1. These findings uncover a direct mechanism of CaMKII (show CAMK2G Proteins) regulation by metabolism and further highlight the importance of metabolism in preserving oocyte viability.

  2. analysis of metabolic regulation of CaMKII (show CAMK2G Proteins) protein and caspases in Xenopus laevis egg extracts

  3. Characterization of a central Ca2 (show CA2 Proteins)+/calmodulin (show Calm2 Proteins)-dependent protein kinase (show CSNK1D Proteins) IIalpha/beta binding domain in densin that selectively modulates glutamate (show GRIN2A Proteins) receptor subunit phosphorylation.

Human Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) interaction partners

  1. CaMKII (show CAMK2G Proteins)-mediated recruitment and upregulation of CYLD (show CYLD Proteins) is expected to remove K63-linked polyubiquitins and facilitate proteasomal degradation at the postsynaptic density.

  2. CAMK2A SNPs were associated with Alzheimer disease and mild cognitive impairment. AG genotype at the CAMK2A-rs3822606 was associated with AD risk.

  3. CaMKII (show CAMK2G Proteins) phosphorylates SCN5A (show SCN5A Proteins) in vitro on 23 novel serine sites as was identified by mass spectrometry; reduced S516 phosphorylation has been found in human heart failure.

  4. Ca2+/calmodulin-dependent protein kinase-II (CaMKII) has a key role in the plasticity of glutamatergic synapses of the brain.

  5. we describe for the first time, two patients with MFD (show SCYL1 Proteins) and ID and for whom a deletion encompassing TCOF1 (show TCOF1 Proteins) and CAMK2A has been identified

  6. a novel regulation of CaMKII (show CAMK2G Proteins) by another second messenger system and indicate its involvement in excitotoxic neuronal cell death.

  7. Overexpression of a T253D phosphomimic form of calcium/calmodulin-dependent protein kinase type II subunit alpha significantly decreases proliferation, and cells accumulate in mitosis, specifically in metaphase.

  8. results suggest that the CAMK2A gene may influence spatial and non-SWM performance in humans without any corresponding gross changes in frontal cortex or hippocampal anatomy.

  9. found seven significant associations between CAMK2A SNPs and alcohol dependence, one of which in an autophosphorylation-related area of the gene.

  10. These results suggest that Osterix (show SP7 Proteins) is a novel target of CaMKII (show CAMK2G Proteins) and the activity of Osterix (show SP7 Proteins) can be modulated by a novel mechanism involving CaMKII (show CAMK2G Proteins) during osteoblast differentiation.

Mouse (Murine) Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) interaction partners

  1. Pharmacological and genetic studies using CaMKII (show CAMK2G Proteins) antagonists and genetically modified [alpha]-CaMKII (show CAMK2G Proteins) mice have shown that blockade or reduction of CaMKII (show CAMK2G Proteins) reduces nicotine reward

  2. The study shows advanced glycation end products (AGEs) resulted from ribosylation activate calcium-/calmodulin-dependent protein kinase type II (CaMKII (show CAMK2G Proteins)), a key kinase responsible for Tau hyperphosphorylation.

  3. HDAC2 (show HDAC2 Proteins) may regulate the expression of immediate early (show JUN Proteins) genes, in part, by prolonging the actions of pCREB in the mouse nucleus accumbens.

  4. The results suggest that CaMKII (show CAMK2G Proteins)-dependent TnI (show TNNI2 Proteins) phosphorylation is involved in FDMCD and the consequent FDAR and that CaMKII (show CAMK2G Proteins) inhibition removes this mechanism and thus induces diastolic dysfunction.

  5. Results indicate that alpha-Ca(2+)/calmodulin-dependent protein kinase II overexpression in the forebrain impairs behavioral flexibility and NMDAR (show GRIN1 Proteins)-dependent long-term depression in the medial prefrontal cortex.

  6. As up-regulation of epithelial barriers is essential for the prevention of chronic inflammatory diseases, the identification of CaMKII (show CAMK2G Proteins) as a modulator of TJ function paves the way for the development of new drugs to treat these diseases.

  7. Binge-like drinking decreased Camk2a phosphorylation in amygdala from adolescent mice, with no effect in adult mice.

  8. This study show that CaMKII (show CAMK2G Proteins) regulates the flow of sensory information in Abeta (show APP Proteins)-LTMR sensory neurons at multiple levels, including impulse generation, Action potential propagation, and dorsal horn synaptic transmission

  9. CaMKIIalpha selectively regulates mGluR1a and mGluR5a ERK1/2 signaling.

  10. Results identify CaMKII (show CAMK2G Proteins) isoform phosphorylation sites and a network of synaptic protein interactions that are sensitive to the abrogation of Thr286 autophosphorylation of CaMKIIa

Rabbit Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) interaction partners

  1. We conclude that ouabain, even at low concentrations (0.5-8.0 mum), can increase INaL and reverse INCX , and these effects may contribute to the effect of the glycoside to increase Ca(2 (show CA2 Proteins)+) transients and contractility.

  2. Data indicate that nitric oxide directly affects Ca-calmodulin (show CALM Proteins)-dependent protein kinase (show CDK7 Proteins) (CaMKII (show CAMK2G Proteins)) to sustain its activity leading to the increase in sarcoplasmic reticulum calcium leak.

  3. Data indicate that the CaMKII (show CAMK2G Proteins) inhibitor, KN-93, can inhibit early afterdepolarizations (EADs), resulting in the suppression of torsades de pointes (TDP) induced by long-QT (LQT (show ARFGAP1 Proteins)) syndrome without affecting transmural dispersion of repolarization (TDR).

  4. CaMKII (show CAMK2G Proteins) signaling, a crucial element of normal automaticity in rabbit sinoatrial node cells (SANC), is also involved in SANC bioenergetics.

CAMK2A Protein Profile

Protein Summary

The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene.

Alternative names and synonyms associated with CAMK2A

  • calcium/calmodulin-dependent protein kinase II alpha (CAMK2A)
  • calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha (camk2a)
  • calcium/calmodulin-dependent protein kinase II alpha (Camk2a)
  • camk2 protein
  • camk2b protein
  • CAMKA protein
  • CaMKII protein
  • mKIAA0968 protein
  • PK2CDD protein
  • PKCCD protein
  • R74975 protein
  • zgc:112538 protein
  • zgc:123320 protein

Protein level used designations for CAMK2A

calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha , calcium/calmodulin-dependent protein kinase II beta , calmodulin dependent protein kinase II beta subunit , calcium/calmodulin-dependent protein kinase II alpha , calcium/calmodulin-dependent protein kinase type II subunit alpha , camk2a1 , CaM kinase II alpha subunit , CaM-kinase II alpha chain , CaMK-II alpha subunit , CaMKIINalpha , caM kinase II subunit alpha , caMK-II subunit alpha , calcium/calmodulin-dependent protein kinase II alpha-B subunit , calcium/calmodulin-dependent protein kinase type II alpha chain , CaMK II , alpha-CaMKII , Ca2+/calmodulin-dependent protein kinase II alpha , alpha CaM kinase II , caM-kinase II alpha chain , calcium/calmodulin-dependent protein kinase II alpha subunit , calcium/calmodulin-dependent protein kinase type II alpha , Calcium/calmodulin-dependent protein kinase type II alpha chain , calcium/calmodulin-dependent protein kinase IIA

462189 Pan troglodytes
399284 Xenopus laevis
550436 Danio rerio
815 Homo sapiens
12322 Mus musculus
25400 Rattus norvegicus
374175 Gallus gallus
530719 Bos taurus
612941 Canis lupus familiaris
100341507 Oryctolagus cuniculus
100727059 Cavia porcellus
100172212 Pongo abelii
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