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anti-Human PLCD1 Antibodies:
anti-Mouse (Murine) PLCD1 Antibodies:
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Human Polyclonal PLCD1 Primary Antibody for IHC, IHC (p) - ABIN4345343
Kiuru, Kurban, Itoh, Petukhova, Shimomura, Wajid, Christiano: Hereditary leukonychia, or porcelain nails, resulting from mutations in PLCD1. in American journal of human genetics 2011
The PLCdelta1 negatively regulates autophagy, and PLCdelta1 suppression contributes to the tolerance of CRC cells harboring KRAS mutations to nutrient deprivation and anti-cancer drug treatment.
Phospholipase C delta 1 is both a KLF15-regulated gene and a novel repressor of airway smooth muscle hypertrophy.
High PLC (show HSPG2 Antibodies) delta expression is associated with breast cancer.
slow phase of Gi/o-mediated TRPC4 (show TRPC4 Antibodies) activation was diminished by inhibiting RhoA (show RHOA Antibodies) or enhancing PLCdelta function
Neuropeptide Y (show NPY Antibodies) decreased PLCD1 expression in HUVECs.
PLC (show HSPG2 Antibodies)-delta1 and TRPV6 (show TRPV6 Antibodies) are critical actor of Ca(2 (show CA2 Antibodies)+) homeostasis in CF human bronchial epithelial cells.
Ectopic expression of PLCD1 inhibits breast tumor cell proliferation in vivo by inducing apoptosis and suppressed tumor cell migration by regulating cytoskeletal reorganization.
Provide evidence for intramolecular interactions in the PLC (show HSPG2 Antibodies)-delta1 PH domain.
Genotyping using microsatellite markers linked the families to the gene PLCD1 on chromosome 3p22.2. Sequence analysis of the gene detected one novel (p.Ser740ArgfsX19) and one previously reported mutation (p.Arg437X).
A novel mutation in the PLCD1 gene, which leads to an aberrant splicing event, underlies autosomal recessive leuconychia.
Data show that phospholipase C delta1 (PLCD1) transfection can induce the apoptosis of CAPAN-1 and BXPC-3 pancreatic cancer cells, arrest the cell cycle in G0 /G1 phase.
the Ca(2 (show CA2 Antibodies)+) dependence of the interaction between PRIP (show NCOA6 Antibodies)-C2 and Syt1 (show SYT1 Antibodies)-C2A was attributed to Ca(2 (show CA2 Antibodies)+) binding with Syt1 (show SYT1 Antibodies)-C2A, but not PRIP (show NCOA6 Antibodies)-C2, using a series of mutants prepared from both C2 domains.
Expression of PLCdelta1 is increased in ALS mouse spinal cord and in neurons from ALS mice. Genetic ablation of this protein in ALS mice significantly increases survival
Identification, characterization and regulatory properties of a novel PLCD1 isoform in mouse.
Plcd1 and Plcd3 (show PLCd3 Antibodies) have synergistic effects on the murine hair follicle in specific regions of the body surface.
Loss of phospholipase Cdelta1 from keratinocytes causes features of interleukin-17 (show IL17A Antibodies)-associated inflammatory skin diseases.
Results suggest that phospholipase C delta(1) is required for skin stem cell lineage commitment.
the PLC (show HSPG2 Antibodies)-delta1 promoter is under the control of NF-kappaB (show NFKB1 Antibodies), which mediates the expression of PLC (show HSPG2 Antibodies)-delta due to Abeta42
Nuclear translocation of phospholipase C-delta1 is linked to the cell cycle and nuclear phosphatidylinositol 4,5-bisphosphate
Data indicate that receptor-triggered phospholipase C (show PLC Antibodies) activity is enhanced by positive feedback from Ca2 (show CA2 Antibodies)+ entering the cytoplasm from intracellular stores and via store-operated channels in the plasma membrane.
This gene encodes a member of the phospholipase C family. Phospholipase C isozymes play critical roles in intracellular signal transduction by catalyzing the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers diacylglycerol (DAG) and inositol triphosphate (IP3). The encoded protein functions as a tumor suppressor in several types of cancer, and mutations in this gene are a cause of hereditary leukonychia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1
, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1
, phosphoinositide phospholipase C-delta-1
, phospholipase C-III
, PLC-delta 1
, phospholipase C delta 1 Lf
, phospholipase C delta-1
, phospholipase C-delta-1
, Phospholipase C-delta1
, phosphoinositide phospholipase C
, phospholipase C delta 1 long form