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Browse our anti-TCF4 (TCF4) Antibodies

Full name:
anti-Transcription Factor 4 Antibodies (TCF4)
On www.antibodies-online.com are 82 Transcription Factor 4 (TCF4) Antibodies from 20 different suppliers available. Additionally we are shipping TCF4 Kits (10) and TCF4 Proteins (9) and many more products for this protein. A total of 107 TCF4 products are currently listed.
Synonyms:
5730422P05Rik, ASP-I2, bHLHb19, E2-2, e2-A, E2.2, GE2, ITF-2, ITF-2b, ITF2, ME2, MITF-2A, MITF-2B, mTcf-4B, mTcf-4E, PTHS, SEF-2, SEF2, SEF2-1, SEF2-1A, SEF2-1B, Tcf-4, Tcf4, TCF4B, TCF4E, TCF7L2, TFE, XE2, Xtcf-4, Xtcf4

Most Popular Reactivities for anti-TCF4 (TCF4) Antibodies

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anti-Human TCF4 Antibodies:

anti-Mouse (Murine) TCF4 Antibodies:

anti-Rat (Rattus) TCF4 Antibodies:

All available anti-TCF4 Antibodies

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Top referenced anti-TCF4 Antibodies

  1. Human Monoclonal TCF4 Primary Antibody for IHC (p), IP - ABIN264393 : Barker, Huls, Korinek, Clevers: Restricted high level expression of Tcf-4 protein in intestinal and mammary gland epithelium. in The American journal of pathology 1999 (PubMed)
    Show all 5 references for ABIN264393

  2. Human Monoclonal TCF4 Primary Antibody for EMSA, IHC (p) - ABIN264394 : Denys, Jadidizadeh, Amini Nik, Van Dam, Aerts, Alman, Cassiman, Tejpar: Identification of IGFBP-6 as a significantly downregulated gene by beta-catenin in desmoid tumors. in Oncogene 2004 (PubMed)
    Show all 2 references for ABIN264394

  3. Human Monoclonal TCF4 Primary Antibody for IF, ELISA - ABIN520754 : Tanaka, Itoh, Nishiyama, Takezawa, Kurihara, Itoh, Kato: Inhibition of endothelial cell activation by bHLH protein E2-2 and its impairment of angiogenesis. in Blood 2010 (PubMed)
    Show all 2 references for ABIN520754

  4. Human Polyclonal TCF4 Primary Antibody for IF, IP - ABIN318967 : Valenta, Lukas, Doubravska, Fafilek, Korinek: HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies. in The EMBO journal 2006 (PubMed)

  5. Human Monoclonal TCF4 Primary Antibody for IF, WB - ABIN393964 : Eichhoff, Weeraratna, Zipser, Denat, Widmer, Xu, Kriegl, Kirchner, Larue, Dummer, Hoek: Differential LEF1 and TCF4 expression is involved in melanoma cell phenotype switching. in Pigment cell & melanoma research 2011 (PubMed)

  6. Cow (Bovine) Polyclonal TCF4 Primary Antibody for WB - ABIN2792580 : Raurell, Castaño, Francí, García de Herreros, Duñach: Presenilin-1 interacts with plakoglobin and enhances plakoglobin-Tcf-4 association. Implications for the regulation of beta-catenin/Tcf-4-dependent transcription. in The Journal of biological chemistry 2006 (PubMed)

  7. Chicken Polyclonal TCF4 Primary Antibody for WB - ABIN2792579 : Lu, Sheng, Mo, Li, Wu, Shen: A negative regulatory element-dependent inhibitory role of ITF2B on IL-2 receptor alpha gene. in Biochemical and biophysical research communications 2005 (PubMed)

More Antibodies against TCF4 Interaction Partners

Zebrafish Transcription Factor 4 (TCF4) interaction partners

  1. GRG5/AES (show AES Antibodies) interacts with TCF4 (show TCF7L2 Antibodies) and represses Wnt (show WNT2 Antibodies)-mediated transcription both in human cells and zebrafish embryos.

Xenopus laevis Transcription Factor 4 (TCF4) interaction partners

  1. Data indicte that Tcf-1 (show HNF1A Antibodies) and Lef-1 (show LEF1 Antibodies) exhibit a function in the axis induction assay, which is lacking in Tcf-3 (show TCF3 Antibodies) and -4.

  2. Tcf4 (show TCF7L2 Antibodies) transcription factor cooperates in patterning the Xenopus brain.

Human Transcription Factor 4 (TCF4) interaction partners

  1. TCF7L2 (show TCF7L2 Antibodies) was associated with increased risk of impaired glucose metabolism.

  2. Studied promoter methylation of ITF2 and APC (show APC Antibodies) and associated microsatellite instability in two case-case studies nested in colorectal cancer.

  3. Data indicate that triglycerides were significantly associated with the T risk allele of the transcription factor 7-like 2 (TCF7L2 (show TCF7L2 Antibodies)) gene.

  4. Transcription factor 7-like 2 (TCF7L2 (show TCF7L2 Antibodies)) gene encodes the TCF-4 transcription factor, which forms a part of the Wnt (show WNT2 Antibodies) signaling pathway.

  5. The T allele of TCF7L2 (show TCF7L2 Antibodies) rs7903146 polymorphism was associated with susceptibility of gestational diabetes mellitus in overall population in white, Hispanic/Latino and Asian sub-groups. Meta-analysis.

  6. Risk alleles for 6 loci increased glucose levels from birth to 5 years of age (ADCY5 (show ADCY5 Antibodies), ADRA2A (show ADRA2A Antibodies), CDKAL1 (show CDKAL1 Antibodies), CDKN2A (show CDKN2A Antibodies)/B, GRB10 (show GRB10 Antibodies), and TCF7L2 (show TCF7L2 Antibodies)

  7. The T-allele frequencies of TCF7L2 (show TCF7L2 Antibodies) polymorphisms rs12255372 and rs7903146 were 30% (26-35%), 32% (27-37%) and 29% (25-34%), 36% (31-41%), respectively.

  8. the beta-catenin (show CTNNB1 Antibodies)/Tcf4 interaction is disrupted by BC-23

  9. GRbeta bound to the N-terminus domain of TCF-4 its influence on Wnt (show WNT2 Antibodies) signaling required both ligand- and DNA-binding domains. This is enough to maintain the TCF (show HNF4A Antibodies)/LEF activity at a high level in the absence of beta-catenin (show CTNNB1 Antibodies) stabilization.

  10. Despite limited sample size, the study indicates that rs7903146-T allele in TCF7L2 (show TCF7L2 Antibodies) was associated with higher mean nocturnal glucose dependent on body composition, which might suggest that rs7902146 affects liver-specific aspects of glucose metabolism.

Mouse (Murine) Transcription Factor 4 (TCF4) interaction partners

  1. Kaiso (show ZBTB33 Antibodies) and Sox10 (show SOX10 Antibodies) sequentially interact with Tcf7l2 (show TCF7L2 Antibodies) to coordinate the maturation of oligodendrocyte.

  2. TCF4 is a regulator of neuronal intrinsic excitability in part by repression of Kcnq1 (show KCNQ1 Antibodies) and Scn10a (show SCN10A Antibodies).

  3. A disease-promoting role of E2-2 dependent pDCs in the pancreas.

  4. Tcf7l2 (show TCF7L2 Antibodies) plays a cell autonomous role in the control of beta cell function and mass, serving as an important regulator of gene expression and islet cell coordination

  5. Genetic disruption of Itf2 on the Apc (show APC Antibodies)(Min/+) background results in earlier death and a significant increase in tumor number and size in the small intestine.

  6. Tcf7l2 (show TCF7L2 Antibodies) is regulating proinsulin (show INS Antibodies) expression directly via Isl1 (show ISL1 Antibodies), Ins1 and indirectly via MafA (show MAFA Antibodies), NeuroD1 (show NEUROD1 Antibodies) and Pdx1 (show PDX1 Antibodies).

  7. Transcription factor 7-like 2 (show TCF7L2 Antibodies) positively regulates neonatal and postnatal mouse oligodendrocyte differentiation during developmental myelination and remyelination in a manner independent of the Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling pathway.

  8. TCF7L2 (show TCF7L2 Antibodies) expressed in the pancreatic beta cells plays a crucial role in glucose metabolism through regulation of the beta cell mass.

  9. Results show that binding of the transcription factor Tcf4 (show TCF7L2 Antibodies) correlates with hypo-methylation and demonstrate that Tcf4 is one of the factors contributing to formation of differentially methylated regions.

  10. Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) stimulation may repress BACE1 (show BACE Antibodies) transcription via binding of TCF4 to BACE1 (show BACE Antibodies) gene, and therefore, activation of the Wnt (show WNT2 Antibodies) pathway may hold the key to new treatments of Alzheimer disease

TCF4 Antigen Profile

Antigen Summary

This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.

Alternative names and synonyms associated with TCF4

  • transcription factor 7-like 2 (T-cell specific, HMG-box) (TCF7L2) antibody
  • transcription factor 4 (tcf4) antibody
  • transcription factor 4 (TCF4) antibody
  • transcription factor 4 (Tcf4) antibody
  • transcription factor 7 like 2, T cell specific, HMG box (Tcf7l2) antibody
  • transcription factor 7-like 2 (T-cell specific, HMG-box) (LOC396347) antibody
  • 5730422P05Rik antibody
  • ASP-I2 antibody
  • bHLHb19 antibody
  • E2-2 antibody
  • e2-A antibody
  • E2.2 antibody
  • GE2 antibody
  • ITF-2 antibody
  • ITF-2b antibody
  • ITF2 antibody
  • ME2 antibody
  • MITF-2A antibody
  • MITF-2B antibody
  • mTcf-4B antibody
  • mTcf-4E antibody
  • PTHS antibody
  • SEF-2 antibody
  • SEF2 antibody
  • SEF2-1 antibody
  • SEF2-1A antibody
  • SEF2-1B antibody
  • Tcf-4 antibody
  • Tcf4 antibody
  • TCF4B antibody
  • TCF4E antibody
  • TCF7L2 antibody
  • TFE antibody
  • XE2 antibody
  • Xtcf-4 antibody
  • Xtcf4 antibody

Protein level used designations for TCF4

transcription factor 7-like 2 (T-cell specific, HMG-box) , transcription factor 4 , transcription factor 4-like , tcf4l , helix-loop-helix transcription factor , SL3-3 enhancer factor 2 , class B basic helix-loop-helix protein 19 , immunoglobulin transcription factor 2 , ITF-2 , TCF-4 , thyroglobulin promoter transcription factor TFE , transcriptional factor 4 , MITF-2 , Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2) , class A helix-loop-helix transcription factor ME2 , immunoglobulin transcription factor-2 , R8f DNA-binding protein , RITF-2 , SEF-2 , HMG box transcription factor 4 , T-cell factor 4 , T-cell-specific transcription factor 4 , mTCF-4 , transcription factor 7-like 2 , transcription factor 7-like 2, T-cell specific, HMG-box , transcription factor Tcf4 , T-cell factor-4 variant A , T-cell factor-4 variant B , T-cell factor-4 variant C , T-cell factor-4 variant D , T-cell factor-4 variant E , T-cell factor-4 variant F , T-cell factor-4 variant G , T-cell factor-4 variant H , T-cell factor-4 variant I , T-cell factor-4 variant J , T-cell factor-4 variant K , T-cell factor-4 variant L , T-cell factor-4 variant M , T-cell factor-4 variant X2 , hTCF-4

GENE ID SPECIES
100049930 Equus caballus
100445658 Pongo abelii
100526651 Danio rerio
373726 Xenopus laevis
6925 Homo sapiens
403949 Canis lupus familiaris
534935 Bos taurus
21413 Mus musculus
84382 Rattus norvegicus
100511671 Sus scrofa
21416 Mus musculus
395508 Gallus gallus
6934 Homo sapiens
396347 Gallus gallus
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