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Browse our anti-TCF4 (TCF4) Antibodies

Full name:
anti-Transcription Factor 4 Antibodies (TCF4)
On www.antibodies-online.com are 86 Transcription Factor 4 (TCF4) Antibodies from 21 different suppliers available. Additionally we are shipping TCF4 Kits (9) and TCF4 Proteins (9) and many more products for this protein. A total of 110 TCF4 products are currently listed.
Synonyms:
5730422P05Rik, ASP-I2, bHLHb19, E2-2, e2-A, E2.2, GE2, ITF-2, ITF-2b, ITF2, ME2, MITF-2A, MITF-2B, mTcf-4B, mTcf-4E, PTHS, SEF-2, SEF2, SEF2-1, SEF2-1A, SEF2-1B, Tcf-4, Tcf4, TCF4B, TCF4E, TCF7L2, TFE, XE2, Xtcf-4, Xtcf4

Most Popular Reactivities for anti-TCF4 (TCF4) Antibodies

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anti-Human TCF4 Antibodies:

anti-Mouse (Murine) TCF4 Antibodies:

anti-Rat (Rattus) TCF4 Antibodies:

All available anti-TCF4 Antibodies

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Top referenced anti-TCF4 Antibodies

  1. Human Monoclonal TCF4 Primary Antibody for IHC (p), IP - ABIN264393 : Barker, Huls, Korinek, Clevers: Restricted high level expression of Tcf-4 protein in intestinal and mammary gland epithelium. in The American journal of pathology 1999 (PubMed)
    Show all 5 references for ABIN264393

  2. Human Monoclonal TCF4 Primary Antibody for EMSA, IHC (p) - ABIN264394 : Denys, Jadidizadeh, Amini Nik, Van Dam, Aerts, Alman, Cassiman, Tejpar: Identification of IGFBP-6 as a significantly downregulated gene by beta-catenin in desmoid tumors. in Oncogene 2004 (PubMed)
    Show all 2 references for ABIN264394

  3. Human Monoclonal TCF4 Primary Antibody for IF, ELISA - ABIN520754 : Tanaka, Itoh, Nishiyama, Takezawa, Kurihara, Itoh, Kato: Inhibition of endothelial cell activation by bHLH protein E2-2 and its impairment of angiogenesis. in Blood 2010 (PubMed)
    Show all 2 references for ABIN520754

  4. Human Polyclonal TCF4 Primary Antibody for IF, IP - ABIN318967 : Valenta, Lukas, Doubravska, Fafilek, Korinek: HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies. in The EMBO journal 2006 (PubMed)

  5. Human Monoclonal TCF4 Primary Antibody for IF, WB - ABIN393964 : Eichhoff, Weeraratna, Zipser, Denat, Widmer, Xu, Kriegl, Kirchner, Larue, Dummer, Hoek: Differential LEF1 and TCF4 expression is involved in melanoma cell phenotype switching. in Pigment cell & melanoma research 2011 (PubMed)

  6. Cow (Bovine) Polyclonal TCF4 Primary Antibody for WB - ABIN2792580 : Raurell, Castaño, Francí, García de Herreros, Duñach: Presenilin-1 interacts with plakoglobin and enhances plakoglobin-Tcf-4 association. Implications for the regulation of beta-catenin/Tcf-4-dependent transcription. in The Journal of biological chemistry 2006 (PubMed)

  7. Chicken Polyclonal TCF4 Primary Antibody for WB - ABIN2792579 : Lu, Sheng, Mo, Li, Wu, Shen: A negative regulatory element-dependent inhibitory role of ITF2B on IL-2 receptor alpha gene. in Biochemical and biophysical research communications 2005 (PubMed)

More Antibodies against TCF4 Interaction Partners

Zebrafish Transcription Factor 4 (TCF4) interaction partners

  1. GRG5/AES (show AES Antibodies) interacts with TCF4 (show TCF7L2 Antibodies) and represses Wnt (show WNT2 Antibodies)-mediated transcription both in human cells and zebrafish embryos.

Xenopus laevis Transcription Factor 4 (TCF4) interaction partners

  1. Data indicte that Tcf-1 (show HNF1A Antibodies) and Lef-1 (show LEF1 Antibodies) exhibit a function in the axis induction assay, which is lacking in Tcf-3 (show TCF3 Antibodies) and -4.

  2. Tcf4 (show TCF7L2 Antibodies) transcription factor cooperates in patterning the Xenopus brain.

Human Transcription Factor 4 (TCF4) interaction partners

  1. TCF7L2 (show TCF7L2 Antibodies) rs7903146 TT genotype was associated with gastric cancer risk under the recessive genetic model. There was no association between rs12255372 SNP and the susceptibility to developing gastric cancer.

  2. These results may provide a linkage between PCa (show FLVCR1 Antibodies) chemoresistance and exosome regulatory networks and thus lead us to propose that AR, PTEN (show PTEN Antibodies) and TCF4 genes may be the important genes which are regulated by exosome miRNAs in chemoresistance cancer cells.

  3. Obesity interacted with the TCF7L2 (show TCF7L2 Antibodies)-rs7903146 on Type 2 Diabetes(T2D) prevalence. Association of TCF7L2 (show TCF7L2 Antibodies) polymorphism with T2D incidence was stronger in non-obese than in obese subjects. TCF7L2 (show TCF7L2 Antibodies) predictive value was higher in non-obese subjects. We created obesity-specific genetic risk score with ten T2D-polymorphisms and demonstrated for the first time their higher strata-specific predictive value for T2D risk.

  4. we observed Dickkopf-related protein 3 (DKK3) as a direct target of miR-25 in vitro. Upregulation of DKK3 partially attenuated the oncogenic effect of miR-25 on melanoma cells. Ectopic expression of miR-25 in melanoma cells induced beta-catenin accumulation in nuclear and inhibited TCF4 (T cell factor 4) activity, as well as the expression of c-Myc and Cyclin D1.

  5. TCF-4 is a co-activator of NF-kappaB (show NFKB1 Antibodies) p65 (show GORASP1 Antibodies) that promotes MMP-15 (show MMP15 Antibodies) transcription and potentiate the migration activity of the lung cancer cells

  6. Results show that MLL (show MLL Antibodies)-AF9 (show MLLT3 Antibodies) reduces Id2 and increases E2-2 expression to drive and sustain leukemia stem cell potential in MLL (show MLL Antibodies)-rearranged acute myeloid leukemia (show BCL11A Antibodies) (AML (show RUNX1 Antibodies)). Low expression of Id2 or of an Id2 gene signature is associated with poor prognosis in not only MLL (show MLL Antibodies)-rearranged but also t(8;21) AML (show RUNX1 Antibodies) patients.

  7. Studied associations between the TCF7L2 (show TCF7L2 Antibodies) rs7903146 SNP and T2DM as well as evaluated its association with obesity in a sample of Taiwanese adults.

  8. Our findings demonstrate that ENPP1 (show ENPP1 Antibodies), TCF7L2 (show TCF7L2 Antibodies), and FTO (show FTO Antibodies) may predispose to T2DM in the mixed-ancestry population.

  9. G-17 caused the overexpression of beta-catenin (show CTNNB1 Antibodies) and TCF-4.

  10. Analysis of SLC4A11 (show SLC4A11 Antibodies), ZEB1 (show ZEB1 Antibodies), LOXHD1, COL8A2 (show COL8a2 Antibodies) and TCF4 gene sequences in a multi-generational family with late-onset Fuchs corneal dystrophy found no evidence for found polymorophisms causing the disease in this specific pedigree.

Mouse (Murine) Transcription Factor 4 (TCF4) interaction partners

  1. Data indicate that upregulation of E2-2 protein markedly attenuated the inhibitor of DNA-binding 1 (ID1 (show ID1 Antibodies))-mediated increase in endothelial progenitor cells (EPCs) proliferation and migration.

  2. results indicate that miR (show MLXIP Antibodies)-181a-5p promotes 3T3-L1 preadipocyte differentiation and adipogenesis through regulating TGFbeta (show TGFB1 Antibodies)/Smad (show SMAD1 Antibodies) and Wnt (show WNT2 Antibodies) signaling pathway by directly targeting Smad7 (show SMAD7 Antibodies) and Tcf7l2 (show TCF7L2 Antibodies)

  3. Tcf7l2 (show TCF7L2 Antibodies) protein levels decline upon initiation of endocrine differentiation in vivo, disclosing the downregulation of this factor in the developing endocrine compartment.

  4. We conclude that E2-2 inhibited EPC (show TCF21 Antibodies) proliferation via suppressing their autophagy, and E2-2 regulated EPC (show TCF21 Antibodies) autophagy by mediating the expression of ATG7 (show ATG7 Antibodies).

  5. demonstrated that Id1 (show ID1 Antibodies) and E2-2 are critical regulators of EPCs function in vitro. Id1 (show ID1 Antibodies) interacts with E2-2 and relieves the E2-2-mediated repression of FGFR1 (show FGFR1 Antibodies) and VEGFR2 (show KDR Antibodies) expression to modulate EPCs functions

  6. Kaiso (show ZBTB33 Antibodies) and Sox10 (show SOX10 Antibodies) sequentially interact with Tcf7l2 (show TCF7L2 Antibodies) to coordinate the maturation of oligodendrocyte.

  7. TCF4 is a regulator of neuronal intrinsic excitability in part by repression of Kcnq1 (show KCNQ1 Antibodies) and Scn10a (show SCN10A Antibodies).

  8. A disease-promoting role of E2-2 dependent pDCs in the pancreas.

  9. Tcf7l2 (show TCF7L2 Antibodies) plays a cell autonomous role in the control of beta cell function and mass, serving as an important regulator of gene expression and islet cell coordination

  10. Genetic disruption of Itf2 on the Apc (show APC Antibodies)(Min/+) background results in earlier death and a significant increase in tumor number and size in the small intestine.

TCF4 Antigen Profile

Antigen Summary

This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.

Alternative names and synonyms associated with TCF4

  • transcription factor 7-like 2 (T-cell specific, HMG-box) (TCF7L2) antibody
  • transcription factor 4 (tcf4) antibody
  • transcription factor 4 (TCF4) antibody
  • transcription factor 4 (Tcf4) antibody
  • transcription factor 7 like 2, T cell specific, HMG box (Tcf7l2) antibody
  • transcription factor 7-like 2 (T-cell specific, HMG-box) (LOC396347) antibody
  • 5730422P05Rik antibody
  • ASP-I2 antibody
  • bHLHb19 antibody
  • E2-2 antibody
  • e2-A antibody
  • E2.2 antibody
  • GE2 antibody
  • ITF-2 antibody
  • ITF-2b antibody
  • ITF2 antibody
  • ME2 antibody
  • MITF-2A antibody
  • MITF-2B antibody
  • mTcf-4B antibody
  • mTcf-4E antibody
  • PTHS antibody
  • SEF-2 antibody
  • SEF2 antibody
  • SEF2-1 antibody
  • SEF2-1A antibody
  • SEF2-1B antibody
  • Tcf-4 antibody
  • Tcf4 antibody
  • TCF4B antibody
  • TCF4E antibody
  • TCF7L2 antibody
  • TFE antibody
  • XE2 antibody
  • Xtcf-4 antibody
  • Xtcf4 antibody

Protein level used designations for TCF4

transcription factor 7-like 2 (T-cell specific, HMG-box) , transcription factor 4 , transcription factor 4-like , tcf4l , helix-loop-helix transcription factor , SL3-3 enhancer factor 2 , class B basic helix-loop-helix protein 19 , immunoglobulin transcription factor 2 , ITF-2 , TCF-4 , thyroglobulin promoter transcription factor TFE , transcriptional factor 4 , MITF-2 , Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2) , class A helix-loop-helix transcription factor ME2 , immunoglobulin transcription factor-2 , R8f DNA-binding protein , RITF-2 , SEF-2 , HMG box transcription factor 4 , T-cell factor 4 , T-cell-specific transcription factor 4 , mTCF-4 , transcription factor 7-like 2 , transcription factor 7-like 2, T-cell specific, HMG-box , transcription factor Tcf4 , T-cell factor-4 variant A , T-cell factor-4 variant B , T-cell factor-4 variant C , T-cell factor-4 variant D , T-cell factor-4 variant E , T-cell factor-4 variant F , T-cell factor-4 variant G , T-cell factor-4 variant H , T-cell factor-4 variant I , T-cell factor-4 variant J , T-cell factor-4 variant K , T-cell factor-4 variant L , T-cell factor-4 variant M , T-cell factor-4 variant X2 , hTCF-4

GENE ID SPECIES
100049930 Equus caballus
100445658 Pongo abelii
100526651 Danio rerio
373726 Xenopus laevis
6925 Homo sapiens
403949 Canis lupus familiaris
534935 Bos taurus
21413 Mus musculus
84382 Rattus norvegicus
100511671 Sus scrofa
21416 Mus musculus
395508 Gallus gallus
6934 Homo sapiens
396347 Gallus gallus
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