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Browse our anti-TCF4 (TCF4) Antibodies

Full name:
anti-Transcription Factor 4 Antibodies (TCF4)
On are 82 Transcription Factor 4 (TCF4) Antibodies from 21 different suppliers available. Additionally we are shipping TCF4 Kits (9) and TCF4 Proteins (9) and many more products for this protein. A total of 106 TCF4 products are currently listed.
5730422P05Rik, ASP-I2, bHLHb19, E2-2, e2-A, E2.2, GE2, ITF-2, ITF-2b, ITF2, ME2, MITF-2A, MITF-2B, mTcf-4B, mTcf-4E, PTHS, SEF-2, SEF2, SEF2-1, SEF2-1A, SEF2-1B, Tcf-4, Tcf4, TCF4B, TCF4E, TCF7L2, TFE, XE2, Xtcf-4, Xtcf4

Most Popular Reactivities for anti-TCF4 (TCF4) Antibodies

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anti-Human TCF4 Antibodies:

anti-Mouse (Murine) TCF4 Antibodies:

anti-Rat (Rattus) TCF4 Antibodies:

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Top referenced anti-TCF4 Antibodies

  1. Human Monoclonal TCF4 Primary Antibody for IHC (p), IP - ABIN264393 : Barker, Huls, Korinek, Clevers: Restricted high level expression of Tcf-4 protein in intestinal and mammary gland epithelium. in The American journal of pathology 1999 (PubMed)
    Show all 5 references for ABIN264393

  2. Human Monoclonal TCF4 Primary Antibody for EMSA, IHC (p) - ABIN264394 : Denys, Jadidizadeh, Amini Nik, Van Dam, Aerts, Alman, Cassiman, Tejpar: Identification of IGFBP-6 as a significantly downregulated gene by beta-catenin in desmoid tumors. in Oncogene 2004 (PubMed)
    Show all 2 references for ABIN264394

  3. Human Monoclonal TCF4 Primary Antibody for IF, ELISA - ABIN520754 : Tanaka, Itoh, Nishiyama, Takezawa, Kurihara, Itoh, Kato: Inhibition of endothelial cell activation by bHLH protein E2-2 and its impairment of angiogenesis. in Blood 2010 (PubMed)
    Show all 2 references for ABIN520754

  4. Human Polyclonal TCF4 Primary Antibody for IF, IP - ABIN318967 : Valenta, Lukas, Doubravska, Fafilek, Korinek: HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies. in The EMBO journal 2006 (PubMed)

  5. Human Monoclonal TCF4 Primary Antibody for IF, WB - ABIN393964 : Eichhoff, Weeraratna, Zipser, Denat, Widmer, Xu, Kriegl, Kirchner, Larue, Dummer, Hoek: Differential LEF1 and TCF4 expression is involved in melanoma cell phenotype switching. in Pigment cell & melanoma research 2011 (PubMed)

  6. Guinea Pig Polyclonal TCF4 Primary Antibody for WB - ABIN2792580 : Raurell, Castaño, Francí, García de Herreros, Duñach: Presenilin-1 interacts with plakoglobin and enhances plakoglobin-Tcf-4 association. Implications for the regulation of beta-catenin/Tcf-4-dependent transcription. in The Journal of biological chemistry 2006 (PubMed)

  7. Guinea Pig Polyclonal TCF4 Primary Antibody for WB - ABIN2792579 : Lu, Sheng, Mo, Li, Wu, Shen: A negative regulatory element-dependent inhibitory role of ITF2B on IL-2 receptor alpha gene. in Biochemical and biophysical research communications 2005 (PubMed)

More Antibodies against TCF4 Interaction Partners

Zebrafish Transcription Factor 4 (TCF4) interaction partners

  1. GRG5/AES (show AES Antibodies) interacts with TCF4 (show TCF7L2 Antibodies) and represses Wnt (show WNT2 Antibodies)-mediated transcription both in human cells and zebrafish embryos.

Xenopus laevis Transcription Factor 4 (TCF4) interaction partners

  1. Data indicte that Tcf-1 (show HNF1A Antibodies) and Lef-1 (show LEF1 Antibodies) exhibit a function in the axis induction assay, which is lacking in Tcf-3 (show TCF3 Antibodies) and -4.

  2. Tcf4 (show TCF7L2 Antibodies) transcription factor cooperates in patterning the Xenopus brain.

Human Transcription Factor 4 (TCF4) interaction partners

  1. We identify the transcription factors FOXA1 (show FOXA1 Antibodies), MYB (show MYB Antibodies), CDX2 (show CDX2 Antibodies) and TCF7L2 (show TCF7L2 Antibodies) as EPHB2 (show EPHB2 Antibodies) enhancer factors and demonstrate that Snail1 (show SNAI1 Antibodies) indirectly inactivates the EPHB2 (show EPHB2 Antibodies) enhancer by downregulation of FOXA1 (show FOXA1 Antibodies) and MYB (show MYB Antibodies)

  2. We found that TCF7L1 (show TCF3 Antibodies) recruits the C-terminal binding protein (CtBP (show CTBP2 Antibodies)) and histone deacetylase 1 (HDAC1 (show HDAC1 Antibodies)) to the DKK4 (show DKK4 Antibodies) promoter to repress DKK4 (show DKK4 Antibodies) gene expression. In the absence of TCF7L1 (show TCF3 Antibodies), TCF7L2 (show TCF7L2 Antibodies) and beta-catenin (show CTNNB1 Antibodies) occupancy at the DKK4 (show DKK4 Antibodies) promoter is stimulated and DKK4 (show DKK4 Antibodies) expression is increased. These findings uncover a critical role for TCF7L1 (show TCF3 Antibodies) in repressing DKK4 (show DKK4 Antibodies) gene expression to promote the oncogenic potential of CRCs.

  3. Corneal endothelium from FECD (show COL8a2 Antibodies) patients harbors a unique signature of mis (show AMH Antibodies)-splicing events due to CTG TNR (show TNR Antibodies) expansion in the TCF4 gene, consistent with the hypothesis that RNA toxicity contributes to the pathogenesis of FECD (show COL8a2 Antibodies).

  4. nominally significant associations seen between TT genotype and the recessive model of TCF7L2 (show TCF7L2 Antibodies) rs7903146 and increased risk of type 2 diabetes mellitus

  5. Genetic variation at TCF7L2 (show TCF7L2 Antibodies) does not predispose an individual to type 2 diabetes by altering either hepatic or extrahepatic insulin (show INS Antibodies) action.

  6. Results identify TCF4 as a crucial transcriptional regulator required for maintenance of blastic plasmacytoid dendritic cell neoplasm.

  7. Taken together, these results suggest that this newly identified Rock2 (show ROCK2 Antibodies)-beta-catenin (show CTNNB1 Antibodies)/TCF4-SCARA5 (show SCARA5 Antibodies) axis will provide novel insight into the understanding of the regulatory mechanisms of proliferation in human RCC (show XRCC1 Antibodies).

  8. In the sex-combined analyses, we identified one novel locus (TCF7L2/HABP2) for WHRadjBMI and eight previously established loci at P < 5x10-8: seven for BMI, and one for WHRadjBMI in African ancestry individuals. An additional novel locus (SPRYD7/DLEU2) was identified for WHRadjBMI when combined with European GWAS.

  9. In renal transplant patients, TCF7L2 (show TCF7L2 Antibodies) rs7903146 is strongly and independently associated with posttransplant diabetes mellitus and might hold the potential to identify patients at risk for this complication.

  10. Insulin (show INS Antibodies) resistance and sex influence plasma free fatty acid responses amongst carriers of the minor T allele of TCF7L2 (show TCF7L2 Antibodies) rs7903146

Mouse (Murine) Transcription Factor 4 (TCF4) interaction partners

  1. TCF-4 as a co-activator of p65 (show NFkBP65 Antibodies) in the potentiation of proinflammatory cytokine production in macrophages and aggravation of high-fat diet induced chronic inflammation and insulin (show INS Antibodies) resistance in mice.

  2. These findings suggest a unique role for Tcf7l2 (show TCF7L2 Antibodies) in generating distinct neuronal phenotypes from homogeneous progenitor population.

  3. Tcf7l2 (show TCF7L2 Antibodies) may be involved in maintenance of stem/progenitor cells properties.

  4. Data indicate that upregulation of E2-2 protein markedly attenuated the inhibitor of DNA-binding 1 (ID1 (show ID1 Antibodies))-mediated increase in endothelial progenitor cells (EPCs) proliferation and migration.

  5. results indicate that miR (show MLXIP Antibodies)-181a-5p promotes 3T3-L1 preadipocyte differentiation and adipogenesis through regulating TGFbeta (show TGFB1 Antibodies)/Smad (show SMAD1 Antibodies) and Wnt (show WNT2 Antibodies) signaling pathway by directly targeting Smad7 (show SMAD7 Antibodies) and Tcf7l2 (show TCF7L2 Antibodies)

  6. Tcf7l2 (show TCF7L2 Antibodies) protein levels decline upon initiation of endocrine differentiation in vivo, disclosing the downregulation of this factor in the developing endocrine compartment.

  7. We conclude that E2-2 inhibited EPC (show TCF21 Antibodies) proliferation via suppressing their autophagy, and E2-2 regulated EPC (show TCF21 Antibodies) autophagy by mediating the expression of ATG7 (show ATG7 Antibodies).

  8. demonstrated that Id1 (show ID1 Antibodies) and E2-2 are critical regulators of EPCs function in vitro. Id1 (show ID1 Antibodies) interacts with E2-2 and relieves the E2-2-mediated repression of FGFR1 (show FGFR1 Antibodies) and VEGFR2 (show KDR Antibodies) expression to modulate EPCs functions

  9. Kaiso (show ZBTB33 Antibodies) and Sox10 (show SOX10 Antibodies) sequentially interact with Tcf7l2 (show TCF7L2 Antibodies) to coordinate the maturation of oligodendrocyte.

  10. TCF4 is a regulator of neuronal intrinsic excitability in part by repression of Kcnq1 (show KCNQ1 Antibodies) and Scn10a (show SCN10A Antibodies).

TCF4 Antigen Profile

Antigen Summary

This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.

Alternative names and synonyms associated with TCF4

  • transcription factor 7-like 2 (T-cell specific, HMG-box) (TCF7L2) antibody
  • transcription factor 4 (tcf4) antibody
  • transcription factor 4 (TCF4) antibody
  • transcription factor 4 (Tcf4) antibody
  • transcription factor 7 like 2, T cell specific, HMG box (Tcf7l2) antibody
  • transcription factor 7-like 2 (T-cell specific, HMG-box) (LOC396347) antibody
  • 5730422P05Rik antibody
  • ASP-I2 antibody
  • bHLHb19 antibody
  • E2-2 antibody
  • e2-A antibody
  • E2.2 antibody
  • GE2 antibody
  • ITF-2 antibody
  • ITF-2b antibody
  • ITF2 antibody
  • ME2 antibody
  • MITF-2A antibody
  • MITF-2B antibody
  • mTcf-4B antibody
  • mTcf-4E antibody
  • PTHS antibody
  • SEF-2 antibody
  • SEF2 antibody
  • SEF2-1 antibody
  • SEF2-1A antibody
  • SEF2-1B antibody
  • Tcf-4 antibody
  • Tcf4 antibody
  • TCF4B antibody
  • TCF4E antibody
  • TCF7L2 antibody
  • TFE antibody
  • XE2 antibody
  • Xtcf-4 antibody
  • Xtcf4 antibody

Protein level used designations for TCF4

transcription factor 7-like 2 (T-cell specific, HMG-box) , transcription factor 4 , transcription factor 4-like , tcf4l , helix-loop-helix transcription factor , SL3-3 enhancer factor 2 , class B basic helix-loop-helix protein 19 , immunoglobulin transcription factor 2 , ITF-2 , TCF-4 , thyroglobulin promoter transcription factor TFE , transcriptional factor 4 , MITF-2 , Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2) , class A helix-loop-helix transcription factor ME2 , immunoglobulin transcription factor-2 , R8f DNA-binding protein , RITF-2 , SEF-2 , HMG box transcription factor 4 , T-cell factor 4 , T-cell-specific transcription factor 4 , mTCF-4 , transcription factor 7-like 2 , transcription factor 7-like 2, T-cell specific, HMG-box , transcription factor Tcf4 , T-cell factor-4 variant A , T-cell factor-4 variant B , T-cell factor-4 variant C , T-cell factor-4 variant D , T-cell factor-4 variant E , T-cell factor-4 variant F , T-cell factor-4 variant G , T-cell factor-4 variant H , T-cell factor-4 variant I , T-cell factor-4 variant J , T-cell factor-4 variant K , T-cell factor-4 variant L , T-cell factor-4 variant M , T-cell factor-4 variant X2 , hTCF-4

100049930 Equus caballus
100445658 Pongo abelii
100526651 Danio rerio
373726 Xenopus laevis
6925 Homo sapiens
403949 Canis lupus familiaris
534935 Bos taurus
21413 Mus musculus
84382 Rattus norvegicus
100511671 Sus scrofa
21416 Mus musculus
395508 Gallus gallus
6934 Homo sapiens
396347 Gallus gallus
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