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Browse our TCF4 (TCF4) ELISA Kits

Full name:
Transcription Factor 4 ELISA Kits (TCF4)
On www.antibodies-online.com are 10 Transcription Factor 4 (TCF4) ELISA Kits from 5 different suppliers available. Additionally we are shipping TCF4 Antibodies (82) and TCF4 Proteins (9) and many more products for this protein. A total of 107 TCF4 products are currently listed.
Synonyms:
5730422P05Rik, ASP-I2, bHLHb19, E2-2, e2-A, E2.2, GE2, ITF-2, ITF-2b, ITF2, ME2, MITF-2A, MITF-2B, mTcf-4B, mTcf-4E, PTHS, SEF-2, SEF2, SEF2-1, SEF2-1A, SEF2-1B, Tcf-4, Tcf4, TCF4B, TCF4E, TCF7L2, TFE, XE2, Xtcf-4, Xtcf4

More ELISA Kits for TCF4 Interaction Partners

Zebrafish Transcription Factor 4 (TCF4) interaction partners

  1. GRG5/AES (show AES ELISA Kits) interacts with TCF4 (show TCF7L2 ELISA Kits) and represses Wnt (show WNT2 ELISA Kits)-mediated transcription both in human cells and zebrafish embryos.

Xenopus laevis Transcription Factor 4 (TCF4) interaction partners

  1. Data indicte that Tcf-1 (show HNF1A ELISA Kits) and Lef-1 (show LEF1 ELISA Kits) exhibit a function in the axis induction assay, which is lacking in Tcf-3 (show TCF3 ELISA Kits) and -4.

  2. Tcf4 (show TCF7L2 ELISA Kits) transcription factor cooperates in patterning the Xenopus brain.

Human Transcription Factor 4 (TCF4) interaction partners

  1. TCF7L2 (show TCF7L2 ELISA Kits) was associated with increased risk of impaired glucose metabolism.

  2. Studied promoter methylation of ITF2 and APC (show APC ELISA Kits) and associated microsatellite instability in two case-case studies nested in colorectal cancer.

  3. Data indicate that triglycerides were significantly associated with the T risk allele of the transcription factor 7-like 2 (TCF7L2 (show TCF7L2 ELISA Kits)) gene.

  4. Transcription factor 7-like 2 (TCF7L2 (show TCF7L2 ELISA Kits)) gene encodes the TCF-4 transcription factor, which forms a part of the Wnt (show WNT2 ELISA Kits) signaling pathway.

  5. The T allele of TCF7L2 (show TCF7L2 ELISA Kits) rs7903146 polymorphism was associated with susceptibility of gestational diabetes mellitus in overall population in white, Hispanic/Latino and Asian sub-groups. Meta-analysis.

  6. Risk alleles for 6 loci increased glucose levels from birth to 5 years of age (ADCY5 (show ADCY5 ELISA Kits), ADRA2A (show ADRA2A ELISA Kits), CDKAL1 (show CDKAL1 ELISA Kits), CDKN2A/B, GRB10 (show GRB10 ELISA Kits), and TCF7L2 (show TCF7L2 ELISA Kits)

  7. The T-allele frequencies of TCF7L2 (show TCF7L2 ELISA Kits) polymorphisms rs12255372 and rs7903146 were 30% (26-35%), 32% (27-37%) and 29% (25-34%), 36% (31-41%), respectively.

  8. the beta-catenin (show CTNNB1 ELISA Kits)/Tcf4 interaction is disrupted by BC-23

  9. GRbeta bound to the N-terminus domain of TCF-4 its influence on Wnt (show WNT2 ELISA Kits) signaling required both ligand- and DNA-binding domains. This is enough to maintain the TCF (show HNF4A ELISA Kits)/LEF activity at a high level in the absence of beta-catenin (show CTNNB1 ELISA Kits) stabilization.

  10. Despite limited sample size, the study indicates that rs7903146-T allele in TCF7L2 (show TCF7L2 ELISA Kits) was associated with higher mean nocturnal glucose dependent on body composition, which might suggest that rs7902146 affects liver-specific aspects of glucose metabolism.

Mouse (Murine) Transcription Factor 4 (TCF4) interaction partners

  1. Kaiso (show ZBTB33 ELISA Kits) and Sox10 (show SOX10 ELISA Kits) sequentially interact with Tcf7l2 (show TCF7L2 ELISA Kits) to coordinate the maturation of oligodendrocyte.

  2. TCF4 is a regulator of neuronal intrinsic excitability in part by repression of Kcnq1 (show KCNQ1 ELISA Kits) and Scn10a (show SCN10A ELISA Kits).

  3. A disease-promoting role of E2-2 dependent pDCs in the pancreas.

  4. Tcf7l2 (show TCF7L2 ELISA Kits) plays a cell autonomous role in the control of beta cell function and mass, serving as an important regulator of gene expression and islet cell coordination

  5. Genetic disruption of Itf2 on the Apc (show APC ELISA Kits)(Min/+) background results in earlier death and a significant increase in tumor number and size in the small intestine.

  6. Tcf7l2 (show TCF7L2 ELISA Kits) is regulating proinsulin (show INS ELISA Kits) expression directly via Isl1 (show ISL1 ELISA Kits), Ins1 and indirectly via MafA (show MAFA ELISA Kits), NeuroD1 (show NEUROD1 ELISA Kits) and Pdx1 (show PDX1 ELISA Kits).

  7. Transcription factor 7-like 2 (show TCF7L2 ELISA Kits) positively regulates neonatal and postnatal mouse oligodendrocyte differentiation during developmental myelination and remyelination in a manner independent of the Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) signaling pathway.

  8. TCF7L2 (show TCF7L2 ELISA Kits) expressed in the pancreatic beta cells plays a crucial role in glucose metabolism through regulation of the beta cell mass.

  9. Results show that binding of the transcription factor Tcf4 (show TCF7L2 ELISA Kits) correlates with hypo-methylation and demonstrate that Tcf4 is one of the factors contributing to formation of differentially methylated regions.

  10. Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) stimulation may repress BACE1 (show BACE ELISA Kits) transcription via binding of TCF4 to BACE1 (show BACE ELISA Kits) gene, and therefore, activation of the Wnt (show WNT2 ELISA Kits) pathway may hold the key to new treatments of Alzheimer disease

TCF4 Antigen Profile

Antigen Summary

This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.

Alternative names and synonyms associated with TCF4

  • transcription factor 7-like 2 (T-cell specific, HMG-box) (TCF7L2) Elisa Kit
  • transcription factor 4 (tcf4) Elisa Kit
  • transcription factor 4 (TCF4) Elisa Kit
  • transcription factor 4 (Tcf4) Elisa Kit
  • transcription factor 7 like 2, T cell specific, HMG box (Tcf7l2) Elisa Kit
  • transcription factor 7-like 2 (T-cell specific, HMG-box) (LOC396347) Elisa Kit
  • 5730422P05Rik Elisa Kit
  • ASP-I2 Elisa Kit
  • bHLHb19 Elisa Kit
  • E2-2 Elisa Kit
  • e2-A Elisa Kit
  • E2.2 Elisa Kit
  • GE2 Elisa Kit
  • ITF-2 Elisa Kit
  • ITF-2b Elisa Kit
  • ITF2 Elisa Kit
  • ME2 Elisa Kit
  • MITF-2A Elisa Kit
  • MITF-2B Elisa Kit
  • mTcf-4B Elisa Kit
  • mTcf-4E Elisa Kit
  • PTHS Elisa Kit
  • SEF-2 Elisa Kit
  • SEF2 Elisa Kit
  • SEF2-1 Elisa Kit
  • SEF2-1A Elisa Kit
  • SEF2-1B Elisa Kit
  • Tcf-4 Elisa Kit
  • Tcf4 Elisa Kit
  • TCF4B Elisa Kit
  • TCF4E Elisa Kit
  • TCF7L2 Elisa Kit
  • TFE Elisa Kit
  • XE2 Elisa Kit
  • Xtcf-4 Elisa Kit
  • Xtcf4 Elisa Kit

Protein level used designations for TCF4

transcription factor 7-like 2 (T-cell specific, HMG-box) , transcription factor 4 , transcription factor 4-like , tcf4l , helix-loop-helix transcription factor , SL3-3 enhancer factor 2 , class B basic helix-loop-helix protein 19 , immunoglobulin transcription factor 2 , ITF-2 , TCF-4 , thyroglobulin promoter transcription factor TFE , transcriptional factor 4 , MITF-2 , Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2) , class A helix-loop-helix transcription factor ME2 , immunoglobulin transcription factor-2 , R8f DNA-binding protein , RITF-2 , SEF-2 , HMG box transcription factor 4 , T-cell factor 4 , T-cell-specific transcription factor 4 , mTCF-4 , transcription factor 7-like 2 , transcription factor 7-like 2, T-cell specific, HMG-box , transcription factor Tcf4 , T-cell factor-4 variant A , T-cell factor-4 variant B , T-cell factor-4 variant C , T-cell factor-4 variant D , T-cell factor-4 variant E , T-cell factor-4 variant F , T-cell factor-4 variant G , T-cell factor-4 variant H , T-cell factor-4 variant I , T-cell factor-4 variant J , T-cell factor-4 variant K , T-cell factor-4 variant L , T-cell factor-4 variant M , T-cell factor-4 variant X2 , hTCF-4

GENE ID SPECIES
100049930 Equus caballus
100445658 Pongo abelii
100526651 Danio rerio
373726 Xenopus laevis
6925 Homo sapiens
403949 Canis lupus familiaris
534935 Bos taurus
21413 Mus musculus
84382 Rattus norvegicus
100511671 Sus scrofa
21416 Mus musculus
395508 Gallus gallus
6934 Homo sapiens
396347 Gallus gallus
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