Browse our WNT3A Proteins (WNT3A)

Full name:
Wingless-Related MMTV Integration Site 3A Proteins (WNT3A)
On www.antibodies-online.com are 3 Wingless-Related MMTV Integration Site 3A (WNT3A) Proteins from 1 different suppliers available. Additionally we are shipping WNT3A Antibodies (62) and many more products for this protein. A total of 67 WNT3A products are currently listed.
Synonyms:
vt, Wnt-3a
list all proteins Gene Name GeneID UniProt
Mouse WNT3A WNT3A 22416 P27467
Human WNT3A WNT3A 89780 P56704
WNT3A    

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WNT3A Proteins (WNT3A) by Origin

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More Proteins for WNT3A Interaction Partners

Mouse (Murine) Wingless-Related MMTV Integration Site 3A (WNT3A) interaction partners

  1. These results indicate that PEDF (show SERPINF1 Proteins) counters Wnt (show WNT2 Proteins) signaling to allow for osteoblast differentiation and provides a mechanistic insight into how the PEDF (show SERPINF1 Proteins) null state results in OI type VI.

  2. These results suggest novel mechanisms for Wnt3a-induced osteoblast proliferation and cell survival via Npnt (show NPNT Proteins) gene expression

  3. this study shows that the Wnt3a expression levels in dendritic cells influences the generation of memory T cells after 5 days in co-culture with naive T cells through activation of the Wnt (show WNT2 Proteins) canonical pathway

  4. Wnt3a induces Osx (show SP7 Proteins) expression via p38 MAPK (show MAPK14 Proteins) signaling in dental follicle cells. Wnt3a-induced Osx (show SP7 Proteins) expression was inhibited in the presence of p38 mitogen-activated protein kinase (show MAPK14 Proteins) (MAPK (show MAPK1 Proteins)) inhibitors (SB203580 and SB202190) at gene and protein levels, as assessed by real-time PCR and immunocytohistochemistry, respectively.

  5. Furthermore, pigment epithelium-derived factor (PEDF (show SERPINF1 Proteins)), a secreted glycoprotein known for its anti-tumor properties, blocked Wnt3a-directed induction of autophagy proteins. Autophagy inhibition was complemented by reciprocal regulation of the oxidative stress enzymes, superoxide dismutase 2 (SOD2 (show SOD2 Proteins)) and catalase (show CAT Proteins).

  6. Ginkgo biloba exocarp extract inhibits tumor angiogenesis, which may be closely relevant to its effect in blockage of Wnt /beta-catenin-VEGF signaling pathway in Lewis lung carcinoma.

  7. Western blot analysis demonstrated that following BMP2 (show BMP2 Proteins) and BMP7 (show BMP7 Proteins) cotransfection of MC3T3E1 cells, the protein expression levels of BMP2 (show BMP2 Proteins), BMP4 (show BMP4 Proteins), BMP6 (show BMP6 Proteins), BMP7 (show BMP7 Proteins), BMP9 (show GDF2 Proteins) and Wnt3a were increased compared with control cells

  8. Wnt3a promotes macrophage-mediated bacterial killing by elevating CRAMP and BD1 (show DEFB1 Proteins) levels.

  9. Wnt3a acutely reduces nuclear acetyl-CoA (show LPCAT1 Proteins), the necessary substrate for histone acetyltransferases, resulting in a global decrease in histone acetylation.

  10. Wnt3a rapidly activated the cyclic adenosine monophosphate (cAMP)/protein kinase A (PKA) pathway and pharmacological stimulation of cAMP/PKA signaling suppressed osteoclast differentiation

Human Wingless-Related MMTV Integration Site 3A (WNT3A) interaction partners

  1. CPE (show CPE Proteins) through its N'-terminal sequence, forms aggregates with Wnt3a and possible endoplasmic reticulum (ER) stress leading to its loss of function.

  2. Our findings suggest that Pyk2 (show PTK2B Proteins) plays an important role in the coordination of stabilization of beta-catenin (show CTNNB1 Proteins) in the crosstalk between Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) and Wnt (show WNT2 Proteins)/Ca(2 (show CA2 Proteins)+) signaling pathways upon Wnt3a stimulation in differentiating hNPCs.

  3. Macrophage polarization seems to have a key role in the progression of pediatric non-alcoholic fatty liver disease; the modulation of macrophage polarization could drive hepatic progenitor cell response by Wnt3a production and beta-catenin (show CTNNB1 Proteins) phosphorylation.

  4. this study shows that Wnt3a promotes differentiation of dendritic cells, but inhibits their maturation

  5. Taken together, our results suggest that canonical Wnt signaling and its antagonist, sFRP1, regulate proliferation of human CSCs. Furthermore, excess sFRP1 in elderly patients causes CSC aging.

  6. Thus, our findings provide mechanistic insight into the proposed cross-talk between the Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) and Hippo pathways in androgen-independent prostate cancer development.

  7. TGF-beta1 (show TGFB1 Proteins) signaling might have roles in myofibroblast differentiation in response to orthodontic force. We reveal in vitro that both Wnt3a and TGF-b1 promote myofibroblast differentiation from human periodontal ligament cells

  8. Furthermore, pigment epithelium-derived factor (PEDF (show SERPINF1 Proteins)), a secreted glycoprotein known for its anti-tumor properties, blocked Wnt3a-directed induction of autophagy proteins. Autophagy inhibition was complemented by reciprocal regulation of the oxidative stress enzymes, superoxide dismutase 2 (SOD2 (show SOD2 Proteins)) and catalase (show CAT Proteins).

  9. we performed a rescue experiment in the JB6 cell line and found that the inhibitory effect of Wnt5a on cell proliferation could be rescued by the addition of Wnt3a. Our data reveal that Wnt5a suppresses the activation of b-catenin signaling during hair follicle regeneration.

  10. The level of Wnt3a expression in hepatocellular carcinoma(HCC (show FAM126A Proteins)) patients was obviously higher than that in any group of cases with benign liver diseases. The diagnostic specificity or the area under the receiver operating characteristic curve was 94.34 % or 0.994 in Wnt3a and 69.81 % or 0.710 in AFP (show AFP Proteins) for HCC (show FAM126A Proteins), respectively.

WNT3A Protein Profile

Protein Summary

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 96% amino acid identity to mouse Wnt3A protein, and 84% to human WNT3 protein, another WNT gene product. This gene is clustered with WNT14 gene, another family member, in chromosome 1q42 region.

Alternative names and synonyms associated with WNT3A

  • wingless-related MMTV integration site 3A (Wnt3a)
  • wingless-type MMTV integration site family, member 3A (WNT3A)
  • vt protein
  • Wnt-3a protein

Protein level used designations for WNT3A

protein Wnt-3a , vestigial tail

GENE ID SPECIES
22416 Mus musculus
89780 Homo sapiens
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