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Aggrecan (ACAN) ELISA Kits

ACAN encodes a calcium-binding mitochondrial carrier protein. Additionally we are shipping Aggrecan Antibodies (161) and Aggrecan Proteins (22) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
ACAN 176  
ACAN 11595 Q61282
ACAN 58968 P07897
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Top Aggrecan ELISA Kits at

Showing 10 out of 52 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 2.54 ng/mL 6.25-100 ng/mL 96 Tests Log in to see 9 to 11 Days
Rat 0.137 ng/mL 0.31-20 ng/mL 96 Tests Log in to see 9 to 11 Days
Mouse 36 pg/mL 78.12-5000 pg/mL 96 Tests Log in to see 9 to 11 Days
Rabbit 0.156 ng/mL 0.625-40 ng/mL Typical standard curve 96 Tests Log in to see 11 to 13 Days
Cow 1.0 ng/mL 5.0-100 ng/mL 96 Tests Log in to see 11 to 13 Days
Guinea Pig 0.1 ng/mL 2.5-50 ng/mL   96 Tests Log in to see 11 to 13 Days
Chicken 0.094 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 8 to 9 Days
Pig 0.469 ng/mL 0.781-50 ng/mL   96 Tests Log in to see 8 to 9 Days
Monkey 0.1 ng/mL 2.5-50 ng/mL   96 Tests Log in to see 11 to 13 Days
Dog 0.1 ng/mL 2.5-50 ng/mL   96 Tests Log in to see 11 to 13 Days

Top referenced Aggrecan ELISA Kits

  1. Human Aggrecan ELISA Kit for Sandwich ELISA - ABIN415094 : Li, Liang, Tao, Zhou, Li, Chen, Chen: Acidic pH conditions mimicking degenerative intervertebral discs impair the survival and biological behavior of human adipose-derived mesenchymal stem cells. in Experimental biology and medicine (Maywood, N.J.) 2012 (PubMed)
    Show all 6 references for ABIN415094

  2. Rat (Rattus) Aggrecan ELISA Kit for Sandwich ELISA - ABIN432406 : Torricelli, Veronesi, Pagani, Maffulli, Masiero, Frizziero, Fini: In vitro tenocyte metabolism in aging and oestrogen deficiency. in Age (Dordrecht, Netherlands) 2013 (PubMed)
    Show all 3 references for ABIN432406

More ELISA Kits for Aggrecan Interaction Partners

Human Aggrecan (ACAN) interaction partners

  1. Results showed an association between short alleles and lumbar disc herniation (LDH), corroborating the hypothesis that aggrecan with shorter repeat lengths can lead to a reduction in the physiological proteoglycan function of intervertebral disc hydration and, consequently, increased individual susceptibility to LDH.

  2. Citrullinated Proteoglycan (show Vcan ELISA Kits) Aggrecan is a new member of citrullinated proteins identified in human joints.

  3. Idiopathic short stature is due to novel heterozygous mutation of the aggrecan gene.

  4. rs2056202 and rs2292813 in SLC25A12 (show Slc25a12 ELISA Kits) may contribute significantly to autism spectrum disorders risk.

  5. Identification of homozygous deletion in ACAN and other candidate variants in familial classical Hodgkin lymphoma by exome sequencing.

  6. ACAN positive perineuronal nets and glial cells were decreased in the amygdala of szhizophrenia and bipolar disorder patients compared to controls.

  7. An underlying interaction between aggrecan VNTR and obesity in symptomatic lumbar disc herniation.

  8. The results suggest that regions within ACAN is associated with ACL (show ACLY ELISA Kits) injury susceptibility and that genetic sequence variability within genes encoding proteoglycans may potentially modulate the ligament fibril properties.

  9. results suggested that genetic variants in ACAN and MET are associated with HM. Functional roles of ACAN and MET in the development of HM need to be further investigated

  10. Data show there was no significant difference in the aggrecan (ACAN) rs1516797 genotype or allele distributions between the carpal tunnel syndrome (CTS (show TTR ELISA Kits)) and control groups.

Cow (Bovine) Aggrecan (ACAN) interaction partners

  1. the subsequent presentation of aggregan from ECM (show MMRN1 ELISA Kits) leads to CD4 (show CD4 ELISA Kits)(+) T-cell activation and effector cell formation.

  2. Data show that expression of mRNAs for aggrecan, collagen type II, and versican (show Vcan ELISA Kits) were significantly effected by the intervention.

  3. The delayed activation of proMMPs and the relatively low cleavage efficiency of MMPs compared to ADAMTS5 (show ADAMTS5 ELISA Kits) (aggrecanase (show ADAMTS4 ELISA Kits)) explains the minor contribution of the MMP enzymes to aggrecan catabolism in vivo.

  4. Self-adhesion between highly negatively charged aggrecan macromolecules extracted from bovine cartilage extracellular matrix, was investigated.

  5. aggrecanase (show ADAMTS4 ELISA Kits) activity (a) is responsible for early TNFalpha (show TNF ELISA Kits)-dependent aggrecan cleavage and GAG release in the meniscus and (b) might be involved in meniscal degeneration.

  6. Maintenance of structure and organization of extracellular matrix comprising chondron and pericellular microenvironment of chondrocytes in articular cartilage is important for distribution of newly synthesized aggrecan monomers within tissue.

  7. aggrecan plays a protective role in preventing degradation of collagen fibrils

  8. Changes in aggrecan and type II collagen (show COL2A1 ELISA Kits) promoter activity in transfected chondrocyte-laden cylindrical constructs were evaluated in response to a range of loading frequencies and durations.

  9. AGC1 mRNA expression level was upregulated by multidirectional articular motion.

  10. Homozygosity mapping in candidate regions in a small Dexter pedigree suggested aggrecan as the most likely candidate gene. Mutation screening revealed a 4-bp insertion in exon 11 (2266_2267insGGCA) and a second, rarer transition in exon 1 (-198C>T).

Mouse (Murine) Aggrecan (ACAN) interaction partners

  1. Aggrecan has a major role in regulating the expression of key growth factors and signaling molecules during development of cartilaginous tissue and is essential for proper chondrocyte organization, morphology, and survival.

  2. Aggrecan, link protein (show HAPLN1 ELISA Kits) and TN-R (show TNR ELISA Kits) were identified to be essential for the neuroprotective properties of the perineuronal net.

  3. the subsequent presentation of aggregan from ECM (show MMRN1 ELISA Kits) leads to CD4 (show CD4 ELISA Kits)(+) T-cell activation and effector cell formation.

  4. Runx3 (show RUNX3 ELISA Kits) positively regulates aggrecan expression and suggest that its function is more limited to cartilage development than to bone.

  5. The role of ADAMTS5 (show ADAMTS5 ELISA Kits) in tendon is to remove pericellular and interfibrillar aggrecan to maintain the molecular architecture responsible for normal tissue function.

  6. role of ADAMTS5 (show ADAMTS5 ELISA Kits) in dermal repair through CD44 (show CD44 ELISA Kits)-mediated aggrecan accumulation and modulation of transforming growth factor beta1 (TGFbeta1 (show TGFB1 ELISA Kits)) signaling

  7. CSGalNAcT-1 is necessary for normal levels of endochondral ossification, and the decrease in CS amount in the growth plate by its absence causes a rapid catabolism of aggrecan.

  8. Data show that strong aggrecan gene expression was observed in growth plate and articular cartilage as well as the fibrocartilage of meniscus, trachea, and intervertebral disc.

  9. A remote upstream element regulates tissue-specific expression of the rat aggrecan gene

  10. the aggrecan promoter has an osteogenic protein-1 (show BMP7 ELISA Kits) responsive element

Horse (Equine) Aggrecan (ACAN) interaction partners

  1. At 0.1 and 1 microM concentrations, LE135 weakly but significantly increased chondral morphology scores, compared to untreated controls. Lack of aggrecan expression and lack of increased CII:CI ratio, compared to controls, did not affect chondrogenesis.

  2. degenerative suspensory ligament desmitis ligaments showed a 15-fold increase in aggrecan compared to normal

Pig (Porcine) Aggrecan (ACAN) interaction partners

  1. keratan sulphate in the interglobular domain of pig aggrecan has a microstructure that is distinct from keratan sulphate in the keratan sulphate-rich region

Rabbit Aggrecan (ACAN) interaction partners

  1. Aggrecan synthesis in intervertebral disc cells is stimulated by E-cadherin (show CDH1 ELISA Kits).

Aggrecan (ACAN) Antigen Profile

Antigen Summary

This gene encodes a calcium-binding mitochondrial carrier protein. The encoded protein localizes to the mitochondria and is involved in the exchange of aspartate for glutamate across the inner mitochondrial membrane. Polymorphisms in this gene may be associated with autism, and mutations in this gene may also be a cause of global cerebral hypomyelination. Alternatively spliced transcript variants have been observed for this gene.

Gene names and symbols associated with Aggrecan (ACAN) ELISA Kits

  • aggrecan (LOC100380783) antibody
  • aggrecan (ACAN) antibody
  • aggrecan (Acan) antibody
  • aggrecan (AGC) antibody
  • solute carrier family 25 (aspartate/glutamate carrier), member 12 (SLC25A12) antibody
  • Agc antibody
  • Agc1 antibody
  • AGCAN antibody
  • ARALAR antibody
  • b2b183Clo antibody
  • cmd antibody
  • Cspg1 antibody
  • CSPGCP antibody
  • MSK16 antibody
  • SEDK antibody

Protein level used designations for Aggrecan (ACAN) ELISA Kits

aggrecan , aggrecan core protein-like , aggrecan core protein , cartilage-specific proteoglycan core protein , chondroitin sulfate proteoglycan core protein 1 , large aggregating proteoglycan , CSPCP , aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122) , aggrecan epidermal growth factor-like domain-1 , aggrecan 1 , chondroitin sulfate proteoglycan 1 , large aggregating proteoglycan, antigen , aggrecan, structural proteoglycan of cartilage , cartilage aggregating proteoglycan , aggrecan interglobular domain , chondroitin sulfate proteoglycan core protein , araceli hiperlarga , calcium binding mitochondrial carrier superfamily member Aralar1 , calcium-binding mitochondrial carrier protein Aralar1 , mitochondrial aspartate glutamate carrier 1 , solute carrier family 25 (mitochondrial carrier, Aralar), member 12

100380783 Salmo salar
100432072 Pongo abelii
176 Homo sapiens
280985 Bos taurus
403828 Canis lupus familiaris
11595 Mus musculus
58968 Rattus norvegicus
100033876 Equus caballus
397255 Sus scrofa
100731672 Cavia porcellus
395798 Gallus gallus
100009079 Oryctolagus cuniculus
100861256 Capra hircus
443001 Ovis aries
101084542 Felis catus
8604 Homo sapiens
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