Alkaline Phosphatase, Intestinal Proteins (ALPI)

ALPI encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. Additionally we are shipping Intestinal Alkaline Phosphatase Antibodies (279) and Intestinal Alkaline Phosphatase Kits (38) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ALPI 11648  
ALPI 248 P09923
ALPI 24197  
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Top Intestinal Alkaline Phosphatase Proteins at antibodies-online.com

Showing 10 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
HOST_Human Cells Human His tag 50 μg Log in to see 20 to 21 Days
$382.80
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
HOST_Mammalian Cells Mouse Fc Tag   50 μg Log in to see 4 Days
$248.33
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
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Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$3,377.00
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$3,389.83
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HOST_Cow Cow Un-conjugated   5000 units Log in to see 11 to 12 Days
$577.92
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 2 to 3 Days
$310.00
Details

ALPI Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , , , ,
, , ,
Rat (Rattus)

More Proteins for Alkaline Phosphatase, Intestinal (ALPI) Interaction Partners

Mouse (Murine) Alkaline Phosphatase, Intestinal (ALPI) interaction partners

  1. Intestinal alkaline phosphatase is a major regulator of gut (show GUSB Proteins) mucosal permeability and appears to work at least partly through improving tight junction protein (show OCLN Proteins) levels and localization.

  2. Authors found that Akp3(-/-) mice acquired lipopolysaccharide tolerance during postweaning development, suggesting that Akp3 plays an important role in immune education.

  3. Intestinal alkaline phosphatase prevents metabolic syndrome in mice.

  4. It is concluded that CD36 (show CD36 Proteins) exists in its phosphorylated and dephosphorylated states in mouse enterocytes and that pCD36 is a substrate of global intestinal alkaline phosphatase (gIAP).

  5. These data suggest that IAP is a local immunomodulating factor, perhaps regulating LPS-toll-like receptor 4 (show TLR4 Proteins) (TLR4 (show TLR4 Proteins)) interaction between commensal microflora and intestinal epithelium.

  6. Suggest role for lysophosphatidylcholine in brush-border intestinal alkaline phosphatase release and restoration.

  7. Results suggest that intestinal alkaline phosphatase participates in a rate-limiting step regulating fat absorption.

  8. forced high-fat chow induced an 18% greater body weight gain, hepatic steatosis, and visceral fat accumulation in female Akp3(-/-) mice but not in female wild-type controls. there is 2X increase of lipid absorption in Akp3(-/-) male mice.

  9. Intestinal alkaline phosphatase activity may have a role in mediating the accelerated fatty acid intake observed in Akp3 knockout mice fed a high-fat diet.

Human Alkaline Phosphatase, Intestinal (ALPI) interaction partners

  1. Engineering macrophages to eat cancer: from "marker of self" CD47 (show CD47 Proteins) and phagocytosis to differentiation

  2. the results obtained by combining bioinformatics and preclinical studies strongly suggest that targeting TSP-1 (show THBS1 Proteins)/CD47 (show CD47 Proteins) axis may represent a valuable therapeutic alternative for hampering melanoma spreading.

  3. Results indicated that surgical resection combined with anti-CD47 (show CD47 Proteins) blocking immunotherapy promoted an inflammatory response and prolonged survival in xenograft animal model, and is therefore an attractive strategy for clinical translation.

  4. Data indicate alkaline phosphatase (AP) as the primary soluble ectonucleotidase in infants undergoing cardiopulmonary bypass and show decreased capacity to clear AMP (show APRT Proteins) when AP activity decreases post-bypass.

  5. Intestinal alkaline phosphatase is a major regulator of gut (show GUSB Proteins) mucosal permeability and appears to work at least partly through improving tight junction protein (show OCLN Proteins) levels and localization.

  6. Results show that the stronger expression of CD47 (show CD47 Proteins) by cancer cells and larger number of total macrophages/M2 were independently related to shorter survivals.

  7. Prolongation of transient porcine chimerism via transgenic expression of human CD47 (show CD47 Proteins) in a primate model is associated with an immune modulating effect, leading to markedly prolonged survival of donor swine skin xenografts.

  8. CD47 (show CD47 Proteins) is a promising cancer biomarker, and targeting CD47 (show CD47 Proteins) presents an effective and potential therapeutic strategy through synthesized mechanisms

  9. CD47 (show CD47 Proteins) seems to mediate fusion mostly through broad contact surfaces between the partners' cell membrane while syncytin-1 (show ERVW-1 Proteins) mediate fusion through phagocytic-cup like structure.

  10. The results suggested a critical role of CD47 (show CD47 Proteins) in laryngeal squamous cell carcinoma development.

Cow (Bovine) Alkaline Phosphatase, Intestinal (ALPI) interaction partners

  1. Mechanism of IAP action appears to be through dephosphorylation of specific bacterial components, including LPS (show IRF6 Proteins), CpG DNA, and flagellin (show FliC Proteins), and not on live bacteria. IAP likely targets these bacterially derived molecules as gut (show GUSB Proteins) mucosal defense factor.

  2. Secondary structure of CIP after reaction with Co2+ in different conditions.

Intestinal Alkaline Phosphatase (ALPI) Protein Profile

Protein Summary

This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with ALPI

  • alkaline phosphatase, intestinal, tandem duplicate 1 (alpi.1)
  • alkaline phosphatase, intestinal (ALPI)
  • alkaline phosphatase, placental (ALPP)
  • alkaline phosphatase, placental-like 2 (ALPPL2)
  • alkaline phosphatase 3, intestine, not Mn requiring (Akp3)
  • alkaline phosphatase, intestinal (Alpi)
  • CD47 molecule (CD47)
  • 2010001C14Rik protein
  • Akp-3 protein
  • Akp6 protein
  • Alp1 protein
  • ALPI protein
  • dIAP protein
  • gIAP protein
  • IAP protein
  • im:7149588 protein
  • MER6 protein
  • OA3 protein
  • S51097 protein
  • si:ch211-262h13.1 protein
  • wu:fa95f04 protein
  • zgc:110794 protein

Protein level used designations for ALPI

alkaline phosphatase, intestinal.1 , iap , intestinal alkaline phosphatase 1 , intestinal-type alkaline phosphatase , alkaline phosphatase, intestinal , intestinal-type alkaline phosphatase-like , intestinal alkaline phosphatase , Kasahara isozyme , alkaline phosphomonoesterase , glycerophosphatase , intestinal alkaline phosphatase V , alkaline phosphatase 6 , Alkaline phosphatase 1, intestinal, defined by SSR , IAP-1 , IAP-I , intestinal alkaline phosphatase I IAP-I , intestinal-type alkaline phosphatase 1 , CD47 antigen (Rh-related antigen, integrin-associated signal transducer) , CD47 glycoprotein , Rh-related antigen , antigen identified by monoclonal antibody 1D8 , antigenic surface determinant protein OA3 , integrin associated protein , integrin-associated protein , integrin-associated signal transducer , leukocyte surface antigen CD47

GENE ID SPECIES
541539 Danio rerio
100399082 Callithrix jacchus
100437471 Pongo abelii
100465399 Ailuropoda melanoleuca
403736 Canis lupus familiaris
740585 Pan troglodytes
11648 Mus musculus
248 Homo sapiens
280993 Bos taurus
76768 Mus musculus
24197 Rattus norvegicus
424936 Gallus gallus
961 Homo sapiens
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