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Alkaline Phosphatase, Placental Proteins (ALP)

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). Additionally we are shipping ALP Antibodies (233) and ALP Kits (33) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ALP 250 P05187
ALP 100359675  
Mouse ALP ALP 66514 Q8C0M9
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Top ALP Proteins at

Showing 9 out of 13 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
HOST_Escherichia coli (E. coli) Rat His tag,T7 tag 100 μg Log in to see 11 to 13 Days
HOST_Human Human His tag   10 μg Log in to see 11 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
Yeast Human His tag 50 μg Log in to see 20 to 21 Days
HOST_HEK-293 Cells Human His tag   10 μg Log in to see 12 to 15 Days
HOST_Baculovirus infected Insect Cells Human Un-conjugated   10 μg Log in to see 2 to 3 Days
HOST_Escherichia coli (E. coli) Human GST tag   10 μg Log in to see 3 to 4 Days
Human Un-conjugated   2 μg Log in to see 6 Days

ALP Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , ,
, , ,
Rat (Rattus)

More Proteins for Alkaline Phosphatase, Placental (ALP) Interaction Partners

Human Alkaline Phosphatase, Placental (ALP) interaction partners

  1. Concentrations of PLAP were elevated in gingival crevicular fluid of patients with pre-eclampsia.

  2. SALL4 (show SALL4 Proteins) also outperformed PLAP on a small sample of cytology blocks. Although SALL4 (show SALL4 Proteins) is not entirely specific, it is a highly sensitive marker with strong diffuse nuclear reactivity in the majority of MGCTs in the posttreatment setting, at significantly higher levels than PLAP

  3. Multiple negatively charged small molecules interact within the active site of ASRGL1 (show ASRGL1 Proteins) to act as a base in promoting cleavage.

  4. Reduced expression of ASRGL1 (show ASRGL1 Proteins), defined as <75% positively stained tumor cells, was significantly associated with poor prognosis and reduced disease-specific survival in endometrioid endometrial adenocarcinoma (EEA).

  5. Quantum-mechanical computational methods were employed to study the catalytic mechanism of human placental AP (PLAP). An active-site model was used, constructed on the basis of the X-ray crystal structure of the enzyme.

  6. term placental explants, but not their conditioned medium, can de-phosphorylate IGFBP-1 (show IGFBPI Proteins) through the action of placental alkaline phosphatase

  7. Anti-PLAP antibodies may serve as a modular building blocks for the development of targeted therapeutic products, armed with cytotoxic drugs, radionuclides or cytokines as payloads.

  8. A candidate gene, ALPP, encoding the placental alkaline phosphatase, was identified as being potentially involved in recurrent spontaneous abortion.

  9. The objective of the following study was to record the specificity and sensitivity of alpha5(IV) loss, smoothelin (show SMTN Proteins) expression and PLAP expression as markers of gastrointestinal smooth muscle neoplasms

  10. Data indicate that p180 (show MLL Proteins) is required for the efficient targeting of placental alkaline phosphatase (ALPP) mRNA to the endoplasmic reticulum (ER).

ALP Protein Profile

Protein Summary

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.

Gene names and symbols associated with ALP

  • alkaline phosphatase, placental (ALPP)
  • alkaline phosphatase, liver/bone/kidney (alpl)
  • alkaline phosphatase (ALP)
  • alkaline phosphatase (alp)
  • bacterial alkaline phosphatase (phoA)
  • alkaline phosphatase, placental (Alpp)
  • asparaginase like 1 (ASRGL1)
  • asparaginase like 1 (Asrgl1)
  • PDZ and LIM domain 3 (Pdlim3)
  • 2410004D18Rik protein
  • Actn2lp protein
  • Akp2 protein
  • Alp protein
  • ALP1 protein
  • ALPI protein
  • AU040643 protein
  • AW060375 protein
  • CRASH protein
  • DDBDRAFT_0205491 protein
  • DDBDRAFT_0231570 protein
  • DDB_0205491 protein
  • DDB_0231570 protein
  • ECK0378 protein
  • JW0374 protein
  • PALP protein
  • PLAP protein
  • PLAP-1 protein
  • psiA protein
  • zgc:56672 protein

Protein level used designations for ALP

alkaline phosphatase, placental (Regan isozyme) , tissue-nonspecific alkaline phosphatase , alkaline phosphatase , bacterial alkaline phosphatase , Regan isozyme , alkaline phosphatase Regan isozyme , alkaline phosphatase, placental type , alkaline phosphomonoesterase , glycerophosphatase , placental alkaline phosphatase 1 , alkaline phosphatase, intestinal , rCG23846-like , L-asparaginase , L-asparagine amidohydrolase , asparaginase-like 1 protein , asparaginase-like protein 1 , beta-aspartyl-peptidase , isoaspartyl dipeptidase , isoaspartyl peptidase/L-asparaginase , PDZ and LIM domain protein 3 , SK-2 , actinin alpha 2 associated LIM protein , actinin-associated LIM protein , alpha-actinin-2-associated LIM protein

100436725 Pongo abelii
393982 Danio rerio
445994 Takifugu rubripes
8621605 Dictyostelium discoideum AX4
945041 Escherichia coli str. K-12 substr. MG1655
7955440 Escherichia coli BW2952
8180246 Escherichia coli BL21(DE3)
8215011 Escherichia coli O157:H7 str. TW14359
250 Homo sapiens
403736 Canis lupus familiaris
100359675 Rattus norvegicus
80150 Homo sapiens
66514 Mus musculus
114108 Rattus norvegicus
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