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CD177 Molecule Proteins (CD177)

NB1, a glycosyl-phosphatidylinositol (GPI)-linked N-glycosylated cell surface glycoprotein, was first described in a case of neonatal alloimmune neutropenia (Lalezari et al., 1971 [PubMed 5552408]).[supplied by OMIM, Mar 2008].. Additionally we are shipping CD177 Antibodies (129) and CD177 Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat CD177 CD177 499099  
CD177 653579  
Mouse CD177 CD177 68891 Q8R2S8
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Top CD177 Proteins at

Showing 8 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human His tag Human CD177, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. 100 μg Log in to see 2 to 3 Days
HOST_Human Cells Human Fc Tag 100 μg Log in to see 16 Days
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
HOST_Mammalian Cells Human His tag   50 μg Log in to see 5 Days
HOST_Human Human His tag   10 μg Log in to see 11 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
HOST_HEK-293 Human His tag   0.1 mg Log in to see 2 to 3 Days
HOST_Human Human Un-conjugated   10 μg Log in to see 11 to 14 Days

CD177 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , ,
, ,

Top referenced CD177 Proteins

  1. Human CD177 Protein expressed in HEK-293 Cells - ABIN2180708 : Temerinac, Klippel, Strunck, Röder, Lübbert, Lange, Azemar, Meinhardt, Schaefer, Pahl: Cloning of PRV-1, a novel member of the uPAR receptor superfamily, which is overexpressed in polycythemia rubra vera. in Blood 2000 (PubMed)
    Show all 3 references for ABIN2180708

  2. Human CD177 Protein expressed in Human Cells - ABIN2006208 : Kissel, Santoso, Hofmann, Stroncek, Bux: Molecular basis of the neutrophil glycoprotein NB1 (CD177) involved in the pathogenesis of immune neutropenias and transfusion reactions. in European journal of immunology 2001 (PubMed)

More Proteins for CD177 Molecule (CD177) Interaction Partners

Human CD177 Molecule (CD177) interaction partners

  1. Data indicate that high percentage of CD177 antigen-positive neutrophils undergo dynamic change during sepsis.

  2. the CD177 SNP is the primary genetic determinant for HNA-2 deficiency and expression variations. The mechanistic delineation of HNA-2 genetics will enable the development of genetic tests for diagnosis and prognosis of HNA-2-related human diseases.

  3. This is the first report showing a prognostic correlation between CD177 expression and solid tumor behavior.

  4. Skewed low neutrophil CD177(%) is highly associated with clonal myeloid disorders, particularly myelodysplasia, and may be useful for detecting clonal myeloid disorders.

  5. CD177/PECAM-1 (show PECAM1 Proteins) adhesive interaction, while contributing to neutrophil-endothelial cell interaction in neutrophil transendothelial migration, does not contribute to or is redundant in platelet-neutrophil interactions

  6. PRV1 overexpression is associated with Essential Thrombocythemia and Myelofibrosis.

  7. NB1-proteinase 3 (show PRTN3 Proteins) interactions may play a role in aiding neutrophil transmigration.

  8. pivotal role of the NB1-Mac-1 receptor interaction for PR3-ANCA-mediated neutrophil activation

  9. The increased membrane expression of PR3 (show PRTN3 Proteins) found in ANCA-associated systemic vasculitis is not linked directly to circulating PR3 (show PRTN3 Proteins) or PR3 (show PRTN3 Proteins) gene transcription, but is dependent upon CD177 expression and correlated with the transcription of the CD177 gene.

  10. heterophilic PECAM-1 (show PECAM1 Proteins)/CD177 interactions affect the phosphorylation state of PECAM-1 (show PECAM1 Proteins) and endothelial cell junctional integrity in such a way as to facilitate neutrophil transmigration in a previously unrecognized allele-specific manner.

Mouse (Murine) CD177 Molecule (CD177) interaction partners

  1. Herein we established a novel genetic mouse model to study the role of CD177 and found that CD177 plays an important role in neutrophils.

CD177 Protein Profile

Protein Summary

NB1, a glycosyl-phosphatidylinositol (GPI)-linked N-glycosylated cell surface glycoprotein, was first described in a case of neonatal alloimmune neutropenia (Lalezari et al., 1971

Gene names and symbols associated with CD177 Molecule Proteins (CD177)

  • CD177 antigen (Cd177)
  • CD177 molecule (CD177)
  • CD177 molecule pseudogene (CD177P)
  • CD177 antigen-like (LOC711291)
  • 1190003K14Rik protein
  • CD177 protein
  • HNA-2a protein
  • HNA2A protein
  • MGC157159 protein
  • NB1 protein
  • NB1 GP protein
  • Pdp3 protein
  • PRV-1 protein
  • PRV1 protein
  • RGD1562941 protein

Protein level used designations for CD177 Molecule Proteins (CD177)

CD177 antigen , CD177 molecule , CD177 antigen-like , NB1 glycoprotein , cell surface receptor , human neutrophil alloantigen 2a , polycythemia rubra vera 1 , polycythemia rubra vera protein 1

499099 Rattus norvegicus
616350 Bos taurus
653579 Homo sapiens
100453048 Pongo abelii
68891 Mus musculus
711291 Macaca mulatta
57126 Homo sapiens
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