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CD1a Molecule Proteins (CD1A)

CD1A encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. Additionally we are shipping CD1a Molecule Antibodies (514) and CD1a Molecule Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CD1A 909 P06126
Mouse CD1A CD1A 12479 P11609
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Top CD1a Molecule Proteins at

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
HOST_Wheat germ Human GST tag   10 μg Log in to see 9 Days
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days

CD1A Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Wild boar (Sus scrofa)

Top referenced CD1a Molecule Proteins

  1. Human CD1A Protein expressed in Wheat germ - ABIN1348552 : Bechan, Lee, Zajonc, Heckel, Xian, Throsby, van Meijer, Germeraad, Kruisbeek, Egeler, Arceci: Phage display generation of a novel human anti-CD1A monoclonal antibody with potent cytolytic activity. in British journal of haematology 2012 (PubMed)

More Proteins for CD1a Molecule (CD1A) Interaction Partners

Human CD1a Molecule (CD1A) interaction partners

  1. The data show that immunohistochemistry for CD1a and Hsp60 (show HSPD1 Proteins) can be of help in differential diagnosis between Keratoacantomas and well-differentiated forms of squamous cell carcinomas.

  2. NDN (show NDN Proteins) and CD1A are novel prognostic methylation markers in patients with head and neck squamous carcinomas

  3. Findings suggest that dermal survivin (show BIRC5 Proteins)+CD1a+ (CD1a antigen) cell infiltration may be a potential biomarker of systemic sclerosis skin lesions.

  4. plasma-derived lipids drive functional levels of CD1d (show CD1D Proteins) expression.

  5. Studies indicate that many CD1 antigen-restricted T cells do not require foreign antigens for activation but instead can be activated by self-lipids presented by CD1.

  6. High CD1a-positive dendritic cell density is associated with improved disease-free survival in papillary thyroid carcinoma.

  7. the expression of WNT4 (show WNT4 Proteins), a Wnt (show WNT2 Proteins) ligand, and three targets of Wnt (show WNT2 Proteins)-ss-catenin transcription activation, namely, MMP7 (show MMP7 Proteins), cyclinD1 (CD1) and c-MYC (show MYC Proteins) in 141 penile tissue cores from 101 unique samples, were investigated.

  8. Studies indicate that the antigen-presenting molecules CD1 and MHC class I-related protein (MR1 (show MR1 Proteins)) display lipids and small molecules to T cells.

  9. The presence of CD1a(+) T-cells in all of the LCH lesions that we have studied to date warrants further investigation into their biological function to determine whether these cells are important in the pathogenesis of LCH

  10. A polymorphism in human CD1A is associated with susceptibility to tuberculosis.

Mouse (Murine) CD1a Molecule (CD1A) interaction partners

  1. reduced development of atherosclerosis in hyperlipidaemic mice by the NKT (show CTSL1 Proteins) antagonist, without affecting NKT (show CTSL1 Proteins) cell or other lymphocyte numbers, suggests that targeting lesion inflammation via CD1d (show CD1D Proteins)-dependent activation of NKT (show CTSL1 Proteins) cells

  2. the crystal structure of the first peptide identified to bind CD1d (show CD1D Proteins), p99 (show PPP1R10 Proteins), and show that it binds in the antigen-binding groove of CD1d (show CD1D Proteins) in a manner compatible with its presentation to T cell receptors.

  3. regulatory and protective role of CD1d (show CD1D Proteins)-dependent natural killer T cells in contact hypersensitivity, at least in part via regulation of IL-10 (show IL10 Proteins) producing B(regs)

  4. The findings support a model in which low endosomal pH controls stability and lipid raft localization of CD1d (show CD1D Proteins)-glycolipid complexes to regulate the outcome of iNKT cell mediated responses.

  5. affects iNKT cell activation by mast cells and release of both IFN-gamma (show IFNG Proteins) and IL-13 (show IL13 Proteins)

  6. CD1d (show CD1D Proteins) acts as a cell surface receptor that recognizes and binds oxysterols and initializes a pathway connecting oxysterol binding to PPARgamma (show PPARG Proteins) activation

  7. Our results indicate that genetically controlled physiological variation of CD1d (show CD1D Proteins) expression levels modulates iNKT-cell development.

  8. our results demonstrate that both Ets1 (show ETS1 Proteins) and miR (show MLXIP Proteins)-155 can directly regulate the expression of CD1d (show CD1D Proteins) on B-cells

  9. We report a novel dichotomous role of beta2m and CD1d, whereby these molecules differently regulate autoimmunity against phospholipid versus non-phospholipid autoantigens.

  10. CD1d (show CD1D Proteins) is up-regulated in early adipogenesis, and is transcriptionally controlled by CCAAT/enhancer-binding protein (C/EBP)-beta (show CEBPB Proteins) and -delta.

CD1a Molecule (CD1A) Protein Profile

Protein Summary

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternatively spliced transcript variants have been observed, but their biological validity has not been determined.

Gene names and symbols associated with CD1a Molecule Proteins (CD1A)

  • CD1b molecule (CD1B)
  • CD1 antigen (CD1.1)
  • CD1a molecule (CD1A)
  • CD1d1 antigen (Cd1d1)
  • AI747460 protein
  • CD1 protein
  • CD1.1 protein
  • CD1.2 protein
  • Cd1a protein
  • CD1A2 protein
  • CD1B protein
  • Cd1d protein
  • FCB6 protein
  • HTA1 protein
  • Ly-38 protein
  • R4 protein
  • T6 protein

Protein level used designations for CD1a Molecule Proteins (CD1A)

CD1-2 antigen , CD1.2 antigen , CD1A antigen, a polypeptide , CD1a molecule , T-cell surface glycoprotein CD1A2 antigen , T-cell surface glycoprotein CD1b , a polypeptide , T-cell surface glycoprotein CD1a , T-cell surface antigen T6/Leu-6 , cluster of differentiation 1 A , cortical thymocyte antigen CD1A , differentiation antigen CD1-alpha-3 , epidermal dendritic cell marker CD1a , hTa1 thymocyte antigen , CD1b molecule , T-cell surface glycoprotein CD1d1 , antigen-presenting glycoprotein CD1d1

425802 Gallus gallus
396785 Sus scrofa
909 Homo sapiens
610699 Canis lupus familiaris
12479 Mus musculus
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