CD1a Protein (CD1a) (AA 19-300) (His tag)
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- Target See all CD1a Proteins
- CD1a
- Protein Type
- Recombinant
- Protein Characteristics
- AA 19-300
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD1a protein is labelled with His tag.
- Purpose
- Human CD1A Protein
- Sequence
- Asp19-Val300
- Characteristics
- Recombinant Human CD1A Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asp19-Val300.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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CD1a (CD1a) (AA 1-311) protein (GST tag)
CD1a Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
CD1a (CD1a) (AA 17-300) protein (His tag)Crystallography grade CD1a Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
CD1a (CD1a) (AA 17-327) protein (rho-1D4 tag)Crystallography grade CD1a Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
CD1a (CD1a) protein (Myc-DYKDDDDK Tag)CD1a Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
CD1a (CD1a) (AA 19-300) protein (His tag)CD1a Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 85 % by SDS - PAGE SDS
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- CD1a
- Alternative Name
- CD1A (CD1a Products)
- Synonyms
- CD1 Protein, FCB6 Protein, HTA1 Protein, R4 Protein, T6 Protein, CD1A Protein, CD1a molecule Protein, CD1 antigen Protein, T-cell surface glycoprotein CD1a Protein, CD1A Protein, CD1.1 Protein, LOC100156095 Protein, LOC101111409 Protein
- Background
- CD1 proteins are a family of major histocompatibility complex (MHC) class I-like antigen-presenting molecules that present lipids to T cells. The cytoplasmic tails (CTs) of all human CD1 isoforms, with the exception of CD1a, contain tyrosine-based sorting motifs, responsible for the internalization of proteins by the clathrin-mediated pathway. CD1a closer to MHC class I in its trafficking and potential antigen-loading compartments among CD1 isoforms.
- Molecular Weight
- 33.3 kDa. Due to glycosylation, the protein migrates to 48-53 kDa and 13-14 kDa based on Tris-Bis PAGE result.
- NCBI Accession
- NP_001754
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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