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CD6 encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. Additionally we are shipping CD6 Antibodies (225) and CD6 Proteins (14) and many more products for this protein.
Showing 7 out of 19 products:
Human CD6 ELISA Kit for Sandwich ELISA - ABIN1889385
Robinson, Prohaska, Santoro, Robinson, Parnes: Identification of a mouse protein homologous to the human CD6 T cell surface protein and sequence of the corresponding cDNA. in Journal of immunology (Baltimore, Md. : 1950) 1995
this analysis identified 65 proteins not associated before with the Zap70 (show ZAP70 ELISA Kits)-Lat (show LAT ELISA Kits)-SLP-76 (show LCP2 ELISA Kits) network and thus should provide cues for future functional experiments.
The binding sites on CD6 and CD166 (show ALCAM ELISA Kits) have been characterized to show that a SNP in CD6 causes glycosylation that hinders the CD6/CD166 (show ALCAM ELISA Kits) interaction.
CD6 regulatory T cells are characterized by CD6 expression and FOXP3 (show FOXP3 ELISA Kits) expression.
interaction of Galectin-1 (show LGALS1 ELISA Kits) and -3 with CD6
upon T cell activation, SRSF1 (show SRSF1 ELISA Kits) becomes limiting, and its function in CD6 exon 5 splicing is countered by an increase in CD6 transcription, dependent on chromatin acetylation.
The CD6 polymorphism conferred reduced odds of optic neuritis as an attack location
In a Korean population, one SNP in CD6 was associated with neuromyelitis optica.
Our findings reveal that this new MS-associated CD6 risk haplotype significantly modifies expression of CD6 on CD4 (show CD4 ELISA Kits)(+) and CD8 (show CD8A ELISA Kits)(+) T cells.
A novel level of regulation of CD6 function by intracytoplasmic serine phosphorylation.
Data suggest that genetic variations within CD6 and syntaxin binding protein 6 (STXBP6 (show STXBP6 ELISA Kits)) may influence response to TNFalpha (show TNF ELISA Kits) inhibitors in patients with rheumatoid arthritis (RA).
Cd6 is a signaling attenuator whose expression alone, i.e. in the absence of ligand engagement, is sufficient to restrain signaling in T cells.
This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene.
T-cell differentiation antigen CD6
, CD6 antigen
, CD6 antigen, Tp120