CD70 Molecule (CD70) ELISA Kits

The protein encoded by CD70 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. Additionally we are shipping CD70 Antibodies (185) and CD70 Proteins (32) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CD70 21948 O55237
CD70 970 P32970
Anti-Rat CD70 CD70 301132  
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Top CD70 ELISA Kits at

Showing 4 out of 15 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Mouse 10pg/mL 31.2-2000 pg/mL Mouse CD70/TNFSF7/cd27L PicoKine ELISA Kit standard curve 96 Tests Log in to see 4 to 6 Days
Human 0.056 ng/mL 0.156-10 ng/mL 96 Tests Log in to see 15 to 17 Days
Human 0.156-10 ng/mL   96 Tests Log in to see 2 to 3 Days
  96 Tests Log in to see 15 to 18 Days

Top referenced CD70 ELISA Kits

  1. Mouse (Murine) CD70 ELISA Kit for Sandwich ELISA - ABIN1889449 : Arens, Tesselaar, Baars, van Schijndel, Hendriks, Pals, Krimpenfort, Borst, van Oers, van Lier: Constitutive CD27/CD70 interaction induces expansion of effector-type T cells and results in IFNgamma-mediated B cell depletion. in Immunity 2001 (PubMed)
    Show all 2 references for 1889449

More ELISA Kits for CD70 Interaction Partners

Mouse (Murine) CD70 Molecule (CD70) interaction partners

  1. findings demonstrate that host CD70 serves as a unique negative regulator of allogeneic T cell response by contributing to donor T cell apoptosis and inhibiting expansion of donor effector T cells.

  2. CD70 reverse signaling enhances NK cell function and immunosurveillance in CD27 (show CD27 ELISA Kits)-expressing B-cell malignancies.

  3. Mice lacking CD70 did not accumulate memory T cells and did not develop hypertension.

  4. find that while stimulation of CD27 (show CD27 ELISA Kits) in isolation drives weak Eomesodermin (show EOMES ELISA Kits)(hi) T-bet(lo) CD8 (show CD8A ELISA Kits)(+) T-cell responses to OVA immunization

  5. Data show that although CD70 is required for the activation of the antiviral adaptive response, it has a regulatory role in early cytokine responses to viruses such as MCMV, possibly through maintenance of Treg survival and function.

  6. the ability of CD70 to trigger costimulation is self-regulated when it binds its complementary receptor.

  7. under conditions of constitutive CD70 expression reflecting chronic immune activation, the CD27 (show CD27 ELISA Kits)/CD70 system inhibits OC differentiation and favors DC differentiation

  8. mTECs and DCs form dedicated niches in the thymic medulla, in which CD27 (show CD27 ELISA Kits)-CD70 co-stimulation rescues developing Treg cells from apoptosis, subsequent to Foxp3 (show FOXP3 ELISA Kits) induction by TCR and CD28 (show CD28 ELISA Kits) signals.

  9. Expression of CD70 by B cells aggravates experimental autoimmune encephalomyelitis by reducing the number of regulatory T cells.

  10. CD70-deficient mice infected with lymphocytic choriomeningitis virus produced only half as many T8 cells. Viral clearance was substantially delayed. CD70-mediated costimulation is not required for secondary or T4 responses.

Human CD70 Molecule (CD70) interaction partners

  1. This study demonstrated that Expression of CD70 (CD27L) Is Associated With Epithelioid and Sarcomatous Features in IDH (show IDH1 ELISA Kits)-Wild-Type Glioblastoma.

  2. CD27 (show CD27 ELISA Kits) is engaged by CD70 cross-presented by other AML (show RUNX1 ELISA Kits) blasts or stem/progenitor cells in a paracrine manner.

  3. the CD70-CD27 (show CD27 ELISA Kits) pathway appears to be a crucial component of EBV-specific T cell immunity and more generally for the immune surveillance of B cells and may be a target for immunotherapy of B cell malignancies.

  4. human CD70-CD27 (show CD27 ELISA Kits) interactions therefore play a nonredundant role in T and B cell-mediated immunity, especially for protection against EBV and humoral immunity.

  5. These data demonstrate the important role of the CD70/CD27 (show CD27 ELISA Kits) axis in immune responses in HTLV-1 carriers and ATL patients.

  6. CD70: An emerging target in cancer immunotherapy

  7. Both monomeric and trimeric forms of CD70 were detected in tumour cell membrane fractions, whereas cytoplasmic fractions contained almost exclusively monomeric CD70

  8. CD70 is overexpressed in systemic lupus erythematosus CD4 (show CD4 ELISA Kits)+ T cells, but expression is not linked to the typical clinical and serological parameters associated with the disease.

  9. CD70-blocking of alphaDC1s from both controls and patients with chronic lymphocytic leukaemia had a negative influence on the production of both IL-12p70 and the Th1 (show TH1L ELISA Kits) cytokine IFN-gamma (show IFNG ELISA Kits).

  10. These results highlight the importance of the CD27 (show CD27 ELISA Kits)-CD70 costimulation pathway for the development of CMV-specific T cell immunity during acute and persistent infection.

CD70 Antigen Profile

Antigen Summary

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.

Gene names and symbols associated with CD70 Molecule (CD70) ELISA Kits

  • CD70 antigen (Cd70) antibody
  • CD70 molecule (CD70) antibody
  • Cd70 molecule (Cd70) antibody
  • CD27L antibody
  • CD27LG antibody
  • TNFSF7 antibody

Protein level used designations for CD70 Molecule (CD70) ELISA Kits

CD27 ligand , CD27-L , Ki-24 antigen , tumor necrosis factor (ligand) superfamily, member 7 , tumor necrosis factor ligand superfamily member 7 , CD70 antigen , surface antigen CD70

21948 Mus musculus
970 Homo sapiens
733577 Sus scrofa
301132 Rattus norvegicus
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