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anti-Cadherin 2 (CDH2) Antibodies

CDH2 is a classical cadherin from the cadherin superfamily. Additionally we are shipping N-Cadherin Kits (33) and N-Cadherin Proteins (15) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CDH2 12558 P15116
CDH2 83501 Q9Z1Y3
CDH2 1000 P19022
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Top anti-N-Cadherin Antibodies at

Showing 10 out of 310 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Mouse Un-conjugated IHC (fro), WB 0.1 mg Log in to see 6 to 8 Days
Human Mouse Un-conjugated BI, FACS, IF, WB Western blot analysis of N-Cadherin in H9-derived neural stem cells (NSC) and transformed human epithelioid carcinoma (HeLa). A NSC lysate and a HeLa cell lysate (ABIN968535) were probed with Purified Mouse anti-Human CD325 monoclonal antibody at concentrations of 0.5, 0.25, and 0.125 myg/ml (lanes 1, 2, and 3, respectively). N-Cadherin is identified as a band of 130 kDa. 0.1 mg Log in to see 5 to 6 Days
Chicken Mouse Un-conjugated IF, IP, WB Western blot analysis of N-Cadherin on HeLa lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000, lane 4: 1:2000 dilution of anti-N-Cadherin. Immunofluorescent staining of 293 cells with anti- N-cadherin antibody. 50 μg Log in to see 5 to 6 Days
Human Mouse Un-conjugated ICC, FACS, IHC, ELISA, WB Figure 1: Flow cytometric analysis of PC-2 cells using CDH2 mouse mAb (green) and negative control (purple) . Figure 2: Immunofluorescence analysis of A431 cells using CDH2 mouse mAb (green) . Blue: DRAQ5 fluorescent DNA dye. 100 μL Log in to see 3 to 4 Days
Human Rabbit Un-conjugated FACS, IHC (p) 1 mL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti-CDH2/N-cadherin Polyclonal Antibody, Unconjugated (ABIN738726) at 1:200 followed by conjugation to the secondary antibody and DAB staining. Formalin-fixed and paraffin-embedded rat brain labeled with Anti-CDH2/N-cadherin Polyclonal Antibody, Unconjugated (ABIN738726) 1:200, overnight at 4°C, The secondary antibody was Goat Anti-Rabbit IgG, PE conjugated used at 1:200 dilution for 40 minutes at 37°C. 100 μL Log in to see 3 to 7 Days
Human Mouse Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated WB N-Cadherin Polyclonal Antibody 0.1 mg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IHC (p) Flow cytometric analysis of rabbit anti-Cadherin-N (SP90) antibody in HeLa (green) compare to negative control of rabbit IgG (blue). 7 mL Log in to see 21 to 31 Days
Human Mouse Biotin WB   0.1 mg Log in to see 6 to 8 Days

CDH2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Rat (Rattus) , , ,
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Top referenced anti-N-Cadherin Antibodies

  1. Chicken Monoclonal N-Cadherin Primary Antibody for IF, IP - ABIN968249 : Cowin: Unraveling the cytoplasmic interactions of the cadherin superfamily. in Proceedings of the National Academy of Sciences of the United States of America 1994 (PubMed)
    Show all 4 references for ABIN968249

  2. Human Monoclonal N-Cadherin Primary Antibody for BI, FACS - ABIN967678 : Knudsen, Soler, Johnson, Wheelock: Interaction of alpha-actinin with the cadherin/catenin cell-cell adhesion complex via alpha-catenin. in The Journal of cell biology 1995 (PubMed)
    Show all 3 references for ABIN967678

  3. Chicken Monoclonal N-Cadherin Primary Antibody for IHC (fro), WB - ABIN1105630 : Walsh, Barton, Putt, Moore, Kelsell, Spurr, Goodfellow: N-cadherin gene maps to human chromosome 18 and is not linked to the E-cadherin gene. in Journal of neurochemistry 1990 (PubMed)
    Show all 3 references for ABIN1105630

  4. Human Polyclonal N-Cadherin Primary Antibody for IF (p), IHC (p) - ABIN738726 : Liu, Cui, Ao, Zhou, Zhou, Yuan, Xiang, Liu, Cao et al.: Aberrant methylation accounts for cell adhesion-related gene silencing during 3-methylcholanthrene and diethylnitrosamine induced multistep rat lung carcinogenesis associated with overexpression of ... in Toxicology and applied pharmacology 2011 (PubMed)
    Show all 2 references for ABIN738726

  5. Human Monoclonal N-Cadherin Primary Antibody for ICC, FACS - ABIN969038 : Sharma, Henderson: IQ-domain GTPase-activating protein 1 regulates beta-catenin at membrane ruffles and its role in macropinocytosis of N-cadherin and adenomatous polyposis coli. in The Journal of biological chemistry 2007 (PubMed)
    Show all 2 references for ABIN969038

More Antibodies against N-Cadherin Interaction Partners

Xenopus laevis Cadherin 2 (CDH2) interaction partners

  1. the switch from E- to N-cadherin during epithelial-mesenchymal transition is essential for acquisition of Contact inhibition of locomotion behavior.

Mouse (Murine) Cadherin 2 (CDH2) interaction partners

  1. Knock-down of ZBED6 in insulin (show INS Antibodies)-producing cells promotes N-cadherin junctions between beta-cells and neural crest stem cells in vitro.

  2. Knockdown of N-cadherin in 3T3 fibroblasts did not impede gap closure in a soft tissue wound healing model.

  3. N-cadherin modulates Lrp6 (show LRP6 Antibodies)/PTHR1 (show PTH1R Antibodies) interaction, restraining the intensity of parathyroid hormone (show PTH Antibodies)-induced beta-catenin (show CTNNB1 Antibodies) signaling

  4. Specific deletion of Cdh2 in Sertoli cells leads to altered meiotic progression and subfertility of mice.

  5. CRP (show CRP Antibodies) suppresses expression of N-cadherin (p < 0.01), a mesenchymal marker of EMT (show ITK Antibodies), and ZEB-1 (show ZEB1 Antibodies), an EMT (show ITK Antibodies)-related transcription factor (p < 0.01). These findings suggest that CRP (show CRP Antibodies) inhibits EMT (show ITK Antibodies) in a MCA (show RSPH1 Antibodies)-38 tumor-bearing mouse model.

  6. these studies suggest that N-cadherin may represent a viable therapeutic target to prevent the dissemination of MM PCs and delay MM disease progression.

  7. N-cadherin is required for the establishment and maintenance of anterior heart field -cardiac progenitor cells.

  8. delta-Catenin (show CTNND2 Antibodies) Regulates Spine Architecture via Cadherin and PDZ (show INADL Antibodies)-dependent Interactions.

  9. Results demonstrate a novel function for the N-cadherin/beta-catenin (show CTNNB1 Antibodies) complex in regulating ionotropic receptor composition of excitatory synapses

  10. N-cadherin is not essential for healthy enamel development and does not significantly affect the mineralization process.

Zebrafish Cadherin 2 (CDH2) interaction partners

  1. Throughout somitogenesis, Cadherin2 promotes extracellular matrix (ECM (show MMRN1 Antibodies)) assembly along tissue boundaries and inhibits ECM (show MMRN1 Antibodies) assembly in the tissue mesenchyme.

  2. Cdon (show CDON Antibodies) is required to localize N-cadherin to the cell membrane in migratory neural crest cells for directed migration.

  3. shows that a dominant-negative nuclear localization mutant of Sox3 (show SOX3 Antibodies) can cause ectopic expression of organizer genes via a mechanism that activates all of these earlier factors, resulting in later axis duplication including major bifurcations of the CNS.

  4. Genetic suppression of N-cadherin function interferes with basal migration of retinal progenitors and subsequent regeneration of HuC (show ELAVL3 Antibodies)/D(+) inner retinal neurons.

  5. N-cadherin deficiency in Danio does not prevent the first tooth from starting to develop, but stops its development at the early cytodifferentiation stage and completely inhibits the development of the other first-generation teeth.

  6. N-cadherin regulates motor axon growth and branching without severely affecting the mechanisms that control axonal target selection.

  7. Slit-Robo signaling downregulates N-cadherin activity to allow apical retraction in newly generated retinal ganglion cells.

  8. demonstration of a novel mechanism of cell adhesion, mediated by a complex of Protocadherin-19 (Pcdh19 (show PCDH19 Antibodies)) and N-cadherin (Ncad)

  9. zebrafish N-cadherin restricts cell proliferation in the dorsal region of the neural tube by regulating cell-cycle length.

  10. Protocadherin-19 (show PCDH19 Antibodies) and N-cadherin interact to control cell movements during anterior neurulation

Human Cadherin 2 (CDH2) interaction partners

  1. Data show that gene silence of ezrin (show EZR Antibodies) inhibits the proliferation and invasion of prostate cancer PC-3 (show PCSK1 Antibodies) cells, meanwhile the level of E-cadherin (show CDH1 Antibodies) is upregulated and N-cadherin is downregulated.

  2. These data suggest that the number of polyploid giant cancer cells and the EMT (show ITK Antibodies)-related proteins E-cadherin (show CDH1 Antibodies), N-cadherin, and vimentin (show VIM Antibodies) may be valuable biomarkers to assess metastasis in patients with breast cancer.

  3. Targeting N-cadherin may be a promising therapeutic approach, particularly in cisplatin-resistant, therapy refractory and metastatic Germ cell tumor.

  4. Metformin's anti-cancer therapeutic effect is mediated through different molecular mechanism in wild-type vs. deficient N-cadherin cancer cells.

  5. Data show that grape seed proanthocyanidins could inhibit cell proliferation, invasion and migration of A549 cells, which might be related to the down-regulation of epidermal growth factor receptor (show EGFR Antibodies) and N-cadherin and the up-regulation of E-cadherin (show CDH1 Antibodies).

  6. Expression data of NCAD shows no association with advanced gastric cancer brain metastasis.

  7. CDH2 was found to be a susceptibility gene for Gilles de la Tourette syndrome in a Danish cohort.

  8. Existing knowledge regarding the role of CDH2 and CDH11 during development and differentiation in vivo and in vitro is reviewed. [review]

  9. N-cadherin was widely expressed in CRC (show CALR Antibodies) cell lines and silencing of N-cadherin suppressed the proliferation and migration of the CRC (show CALR Antibodies) cell line HT-29 by upregulating E-cadherin (show CDH1 Antibodies), suggesting a potential role of N-cadherin in inducing EMT (show ITK Antibodies).

  10. It was shown that both E- and N-cadherin mRNA and protein are expressed in the human renal proximal tubule.

N-Cadherin (CDH2) Antigen Profile

Protein Summary

This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product.

Gene names and symbols associated with anti-Cadherin 2 (CDH2) Antibodies

  • cadherin 2, type 1, N-cadherin (neuronal) (cdh2) antibody
  • cadherin 2 (Cdh2) antibody
  • cadherin 2, neuronal (cdh2) antibody
  • cadherin 2, type 1, N-cadherin (neuronal) (CDH2) antibody
  • cadherin 2, type 1, N-cadherin (neuronal) (Cdh2) antibody
  • cadherin-2-like (LOC100411112) antibody
  • neural-cadherin-like (LOC427547) antibody
  • Cadherin-2 antibody
  • CD325 antibody
  • CDH2 antibody
  • CDHN antibody
  • CDw325 antibody
  • glo antibody
  • lyr antibody
  • N-cadherin antibody
  • NCAD antibody
  • pac antibody
  • wu:fb47h04 antibody

Protein level used designations for anti-Cadherin 2 (CDH2) Antibodies

cadherin 2, type 1, N-cadherin (neuronal) , cadherin-2 , neural cadherin , cadherin 2 type 1 N-cadherin (neuronal) , N-cadherin , Neural cadherin , glass onion , labyrinth , n-cadherin , parachute , N-cadherin 1 , cadherin 2, N-cadherin (neuronal) , calcium-dependent adhesion protein, neuronal , neural-cadherin , cadherin 2, type 1 preproprotein , cadherin-2-like

495284 Xenopus laevis
100151712 Xenopus (Silurana) tropicalis
12558 Mus musculus
83501 Rattus norvegicus
100689204 Cricetulus griseus
30291 Danio rerio
1000 Homo sapiens
414745 Gallus gallus
281062 Bos taurus
480169 Canis lupus familiaris
100286861 Sus scrofa
101082701 Felis catus
100065078 Equus caballus
100170321 Ovis aries
100328895 Oryctolagus cuniculus
100714783 Cavia porcellus
100411112 Callithrix jacchus
427547 Gallus gallus
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