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Calpastatin (CAST) ELISA Kits

The protein encoded by CAST is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. Additionally we are shipping Calpastatin Antibodies (86) and Calpastatin Proteins (12) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CAST 831 P20810
CAST 25403 P27321
CAST 12380  
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Top Calpastatin ELISA Kits at

Showing 5 out of 13 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Cow 7.81 pg/mL 31.25-2000 pg/mL Typical standard curve 96 Tests Log in to see 11 to 13 Days
Human 0.39 ng/mL 1.56-100 ng/mL Typical standard curve 96 Tests Log in to see 9 to 11 Days
Mouse 0.054 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
Pig 78-5000 pg/mL   96 Tests Log in to see 11 to 13 Days
  96 Tests Log in to see 11 to 13 Days

More ELISA Kits for Calpastatin Interaction Partners

Human Calpastatin (CAST) interaction partners

  1. Loss of CAST in angiogenic ECs facilitates mu (show JAK3 ELISA Kits)-calp (show STAT1 ELISA Kits)ain-induced SOCS3 degradati (show SOCS3 ELISA Kits)on, which amplifies p (show VEGFC ELISA Kits)athological angiogenesis through interleukin-6/STAT3/VEGF-C axis.

  2. We describe PLACK syndrome, as a clinical entity of defective epidermal adhesion, caused by loss-of-function mutations in calpastatin.

  3. Calpastatin binds with Cav1.2 (show CACNA1C ELISA Kits) amino acid motifs in a calcium dependent manner.

  4. Calpastatin gene (CAST) is not associated with late onset sporadic Parkinson's disease in the Han Chinese population.

  5. HER2 (show ERBB2 ELISA Kits) inhibited calpain-1 (show CAPN1 ELISA Kits) activity through upregulating calpastatin, an endogenous calpain inhibitor.

  6. The results suggest that calpain-2 (show CAPN2 ELISA Kits) and calpastatin expression is important in pancreatic cancers, influencing disease progression

  7. Neuronal overexpression of calpastatin modulates amyloid precursor protein (show APP ELISA Kits) processing in brains of transgenic beta-amyloid depositing mice.

  8. Calpastatin overexpression reduces calpain-mediated proteolysis and behavioral impairment after traumatic brain injury.

  9. Mycoplasma hyorhinis membrane lipoproteins induce calpastatin upregulation in human cells

  10. calpastatin-calpain balance varied during Th-1,2, and -17 development; overexpression of a domain of calpastatin suppressed production of IL-6 (show IL6 ELISA Kits) and IL-17 (show IL17A ELISA Kits) by Th cells and of IL-6 (show IL6 ELISA Kits) by fibroblasts; suppression of IL-6 (show IL6 ELISA Kits) occurred by reducing NF-kappaB (show NFKB1 ELISA Kits) signaling

Pig (Porcine) Calpastatin (CAST) interaction partners

  1. CT1 (show SLC6A8 ELISA Kits) decreases cell death through a mechanism related to Stat3 (show STAT3 ELISA Kits) and Akt (show AKT1 ELISA Kits) phosphorylation and activation of calpastatin in D-galactosamine-treated hepatocytes.

  2. CAST gene affected post-mortem activation time of calpain and drip loss.

  3. The quality of meat influenced by RYR1 (show RYR1 ELISA Kits) genotype may be modified by the simultaneous influence of genotype as regards the CAST locus

  4. The effect of the beta-adrenergic agonist clenbuterol and porcine ST (pST (show SULT1A1 ELISA Kits)) treatment on calpastatin promoter usage in vivo and in vitro are reported.

  5. The Decreased expression of calpastatin mRNA during development is highly correlated with muscle protein accumulation in neonatal Sus scrofa.

Cow (Bovine) Calpastatin (CAST) interaction partners

  1. The suppression of calpastatin resulted in the increased expression of mu-calpain (show CAPNL1 ELISA Kits), caspases, and HSPs which in turn regulate apoptotic cell death.

  2. This work is supportive of the importance of CAPN1 (show CAPNL1 ELISA Kits) and CAST for mean tenderness in beef.

  3. bovine CAPN-CAST interaction were well reflected in the geometry between the pharmacophore features and its shape constraints identified using our modeled bovine CAPN1 (show CAPNL1 ELISA Kits)/CAST4 complex structures

  4. CAST binds and inhibits CAPN via its CAPN-inhibitor domains(CAST1-4) .CAST4 docks near the flexible active site of CAPN1 (show CAPNL1 ELISA Kits), conformational changes at the interaction site after binding could be directly related to CAST4 inhibitory activity.

  5. This work confirms the importance of CAPN1 (show CAPNL1 ELISA Kits) and CAST for tenderness in beef, provides a new effect of CAST on beef tenderness, and questions the utility of GHR (show GHR ELISA Kits) as a selection marker for beef quality.

  6. The association of single nucleotide polymorphisms in calpastatin with muscle tenderness was studied.

  7. Association of polymorphisms in calpain 1 (show CAPN1 ELISA Kits), (mu/I) large subunit, calpastatin, and cathepsin D (show CTSD ELISA Kits) genes with meat quality traits in double-muscled Piemontese cattle.

  8. The CAST28 genotypes showing allele frequencies of C (0.429) and T (0.571) were significantly associated with calpastatin activity and Warner-Bratzler Shear Force in beef.

  9. The association of polymorphisms in calpastatin and mu-calpain (show CAPNL1 ELISA Kits) genes with meat tenderness in 3 French beef breeds is reported.

  10. characteristic properties of ER membrane m-calpain (show CAPN2 ELISA Kits) (MCp (show CD46 ELISA Kits)), calpastatins and lumen m-calpain (show CAPN2 ELISA Kits) (LCp (show KLHDC2 ELISA Kits)) and a brief comparative study between MCp (show CD46 ELISA Kits) and LCp (show KLHDC2 ELISA Kits)

Mouse (Murine) Calpastatin (CAST) interaction partners

  1. Defective scar formation after myocardial infarction in calpastatin transgenic mice was associated with blunted CD4 (show CD4 ELISA Kits)(+) T-cell and M2-macrophage recruitment.

  2. Over-expression of Cast inhibits calpain activation and attenuates post-infarction myocardial remodeling.

  3. EC-specific transgenic CAST downregulated JAK (show JAK3 ELISA Kits)/STAT (show STAT1 ELISA Kits) signals, upregulated SOCS3 (show SOCS3 ELISA Kits), and depleted VEGF-C (show VEGFC ELISA Kits), counteracting unstable pathological neovessels and disease progression in tumors and oxygen-induced retinopathy lesions in mice.

  4. Overexpression of the calpain-specific inhibitor calpastatin reduces human alpha-synuclein (show SNCA ELISA Kits) processing, aggregation and synaptic impairment in transgenic mice.

  5. We observed that ischemia induction results in increased expression of CaN, Calp (show KCNIP4 ELISA Kits) and Calpn.

  6. Over-expression of calpastatin enhances doxorubicin-induced cardiac injuries through calpain inhibition.

  7. The calpain/calpastatin system has opposing roles in growth and metastatic dissemination of melanoma.

  8. yeast A34.5/A49 and mammalian PAF49/PAF53 heterodimeric complexes interact through species-specific sequence elements that appear to assume similar structural motifs.

  9. Data show that genetic deficiency of calpastatin (CS) augmented Abeta (show APP ELISA Kits) amyloidosis, tau phosphorylation, microgliosis, and somatodendritic dystrophy, and increased mortality in amyloid precursor protein (APP (show APP ELISA Kits)) transgenic mice.

  10. PIN1 apparently restrains the ability of calpastatin to inhibit calpain, maintaining calpain activity in endothelial cells.

Calpastatin (CAST) Antigen Profile

Antigen Summary

The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene names and symbols associated with Calpastatin (CAST) ELISA Kits

  • calpastatin (calp3) antibody
  • calpastatin (CAST) antibody
  • calpastatin (cast) antibody
  • calpastatin (VDBG_09182) antibody
  • Calpastatin (ical) antibody
  • calpastatin (Cast) antibody
  • CD3E antigen, epsilon polypeptide associated protein (Cd3eap) antibody
  • 1190028F09 antibody
  • 2610103M17Rik antibody
  • ASE-1 antibody
  • Ase1 antibody
  • BS-17 antibody
  • calp3 antibody
  • cast antibody
  • DKFZp469E0716 antibody
  • PAF49 antibody
  • sb:cb966 antibody
  • zgc:194249 antibody

Protein level used designations for Calpastatin (CAST) ELISA Kits

calpastatin , Calpastatin , calpastatin-like , calpain inhibitor , sperm BS-17 component , calpastatin isoform III , calpastatin type I , calpastatin type II , calpastatin type III , A34.5 , CD3 epsilon associated protein; antisense to Ercc1 , CD3-epsilon-associated protein , CD3E-associated protein , DNA-directed RNA polymerase I subunit RPA34 , RNA polymerase I-associated factor PAF49 , anti-sense to ERCC-1 protein

398115 Xenopus laevis
427121 Gallus gallus
462348 Pan troglodytes
563084 Danio rerio
703623 Macaca mulatta
9528399 Verticillium alfalfae VaMs.102
100073225 Equus caballus
100136674 Oncorhynchus mykiss
100145371 Xenopus (Silurana) tropicalis
100174647 Pongo abelii
100380407 Salmo salar
100391897 Callithrix jacchus
831 Homo sapiens
397135 Sus scrofa
281039 Bos taurus
25403 Rattus norvegicus
479148 Canis lupus familiaris
100009098 Oryctolagus cuniculus
12380 Mus musculus
443364 Ovis aries
70333 Mus musculus
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