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anti-Cannabinoid Receptor 2 (CNR2) Antibodies

The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. Additionally we are shipping CNR2 Kits (13) and CNR2 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CNR2 1269 P34972
CNR2 57302 Q9QZN9
CNR2 12802 P47936
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Top anti-CNR2 Antibodies at antibodies-online.com

Showing 10 out of 127 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB CB2 Antibody (C-term) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. CB2 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skin carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CB2 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from COLO205 cells, using CNR2 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated WB Western Blot analysis of CNR2 expression in transfected 293T cell line by CNR2 monoclonal antibody (M01), clone 3C7. Lane 1: CNR2 transfected lysate(39.7 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Goat Un-conjugated ELISA, WB ABIN185485 (2µg/ml) staining of Jurkat lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$326.89
Details
Human Rabbit Un-conjugated IHC (p), WB Immunohistochemical analysis of paraffin-embedded breast ca, using Cannabinoid Receptor 2 antibody at 1/250dilution. Western blot analysis using Cannabinoid Receptor 2 antibodyCat.-No AP31916PU-N at 1/1000 dilution.Sample (30 ug of whole cell lysate), 10% SDS PAGEA: Molt-4 0.1 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated FACS, ICC, IF, IHC, IHC (fro), IHC (p), WB Western Blot: Cannabinoid R2/CB2/CNR2 Antibody [ABIN152759] - Analysis of 25 ug of PC-3 (lane 1) and Jurkat (lane 2) cell lysates. 0.1 mL Log in to see 7 to 9 Days
$408.19
Details
Horse Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB CB2 Antibody (C-term) (ABIN654631) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated WB   0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Mouse Un-conjugated IF, ELISA, WB Western Blot analysis of CNR2 expression in transfected 293T cell line by CNR2 monoclonal antibody (M01), clone 3C7.Lane 1: CNR2 transfected lysate(39.7 KDa).Lane 2: Non-transfected lysate. Immunofluorescence of monoclonal antibody to CNR2 on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Log in to see 9 Days
$430.00
Details

CNR2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CNR2 Antibodies

  1. Human Monoclonal CNR2 Primary Antibody for WB - ABIN393322 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 5 references for ABIN393322

  2. Human Polyclonal CNR2 Primary Antibody for EIA, FACS - ABIN951020 : Larrinaga, Varona, Pérez, Sanz, Ugalde, Cándenas, Pinto, Gil, López: Expression of cannabinoid receptors in human kidney. in Histology and histopathology 2010 (PubMed)
    Show all 5 references for ABIN951020

  3. Human Polyclonal CNR2 Primary Antibody for FACS, ICC - ABIN152759 : Patsenker, Stoll, Millonig, Agaimy, Wissniowski, Schneider, Mueller, Brenneisen, Seitz, Ocker, Stickel: Cannabinoid receptor type I modulates alcohol-induced liver fibrosis. in Molecular medicine (Cambridge, Mass.) 2012 (PubMed)

  4. Human Monoclonal CNR2 Primary Antibody for IF, ELISA - ABIN514506 : Brocato, Zoerner, Janjetovic, Skobowiat, Gupta, Moore, Slominski, Zhang, Schenone, Phinehas, Ferry, Dick, Hubbard, Mari, Schlabritz-Loutsevitch: Endocannabinoid crosstalk between placenta and maternal fat in a baboon model (Papio spp.) of obesity. in Placenta 2013 (PubMed)

  5. Human Polyclonal CNR2 Primary Antibody for ELISA, WB - ABIN185485 : Van Sickle, Duncan, Kingsley, Mouihate, Urbani, Mackie, Stella, Makriyannis, Piomelli, Davison, Marnett, Di Marzo, Pittman, Patel, Sharkey: Identification and functional characterization of brainstem cannabinoid CB2 receptors. in Science (New York, N.Y.) 2005 (PubMed)

  6. Human Polyclonal CNR2 Primary Antibody for ELISA, WB - ABIN1535662 : Munro, Thomas, Abu-Shaar: Molecular characterization of a peripheral receptor for cannabinoids. in Nature 1993 (PubMed)

More Antibodies against CNR2 Interaction Partners

Cow (Bovine) Cannabinoid Receptor 2 (CNR2) interaction partners

  1. Histological analyses revealed numerous endocrinal cell clusters or islets which were distributed among exocrine adenomeri in connectival tissue. Immunohistochemistry showed that endocrine-islets contained some CB2-positive cells with a very peculiar localization that is a few primarily localized at the edges of islets and some of them also scattered in the center of the cluster.

Zebrafish Cannabinoid Receptor 2 (CNR2) interaction partners

  1. genetic or chemical inhibition of cannabinoid receptor (Cnr (show PCDHA1 Antibodies)) activity disrupts liver development and metabolic function in zebrafish.

  2. Cannabinoid Receptor-2 Regulates Embryonic Hematopoietic Stem Cell Development via Prostaglandin E2 and P-Selectin (show SELP Antibodies) Activity.

  3. Activation of the Cnr2 receptor inhibits leukocyte migration in response to acute injury.

Human Cannabinoid Receptor 2 (CNR2) interaction partners

  1. Cannabinoid Receptor 2 mutation is associated with obesity.

  2. The type 2 cannabinoid (Cnr2) receptor is implicated in cancer, bone metabolism and pain perception. Emerging data have uncovered the role of Cnr2 in the regulation of tumour-bone cell interactions and suggest that agents that target Cnr2 in the skeleton have potential efficacy in the reduction of skeletal complications associated with cancer. [review]

  3. The prevalence of chronic HCV infected patients with the CB2-63 RR variant was significantly higher in the immune-mediated disorder (IMD (show ADM2 Antibodies)) than in the non-IMD (show ADM2 Antibodies) group. The data suggest a significant, previously unknown, independent association between the CB2-63 RR variant and IMDs (show ADM2 Antibodies) in anti-HCV-positive patients.

  4. Data indicate that mobile tongue squamous cell carcinoma (SCC (show CYP11A1 Antibodies)) patients presenting enhanced cannabinoid receptors CB1R (show CNR1 Antibodies), CB2R, or concomitant CB1R (show CNR1 Antibodies)/CB2R expression showed significantly longer overall and disease-free survival times compared to those with low expression.

  5. This is the first demonstration that the fibroblasts of the muscular fasciae express CB1 (show CNR1 Antibodies) and CB2.

  6. Induction of apoptosis was mediated via CB1 (show CNR1 Antibodies) as well as CB2, and expression of CB receptors was a prerequisite for therapy response in our models.

  7. CNR2 gene has an important role in the etiology of osteoporosis and suggest that it may be a genetic risk factor for BMD and osteoporosis in Han Chinese postmenopausal women.

  8. Human lung-resident macrophages express CB1 (show CNR1 Antibodies) and CB2 receptors whose activation inhibits the release of angiogenic and lymphangiogenic factors

  9. A histological activity index (HAI (show SPINT1 Antibodies)) > 8 (Ishak scoring) was more frequent in patients with CB2-63 RR than in those with CB2-63 QR or QQ (37% vs. 16.7%, p < 0.05).

  10. Study demonstrates the up-regulation of CB2 receptors in glial elements in postmortem tissues of Parkinson's disease patients and an inflammatory mouse model

Mouse (Murine) Cannabinoid Receptor 2 (CNR2) interaction partners

  1. Data show that (-)-beta-caryophyllene (BCP (show OPN1SW Antibodies)) diminished axonal demyelination and modulated Th1 (show HAND1 Antibodies)/Treg immune balance through the activation of cannabinoid receptor type 2 (CB2 receptor).

  2. Study demonstrated that the activation of CB2R attenuates the ocular pathology associated with the development and progression of experimental proliferative vitreoretinopathy; intervention at early stage proliferative vitreoretinopathy with CB2R agonists reduces ocular inflammation and disease severity.

  3. the M2 macrophage chemokine CCL17 was identified as an essential factor for enhanced survival in the absence of CB2, because CCL17 x Cnr2 double-deficient mice were fully susceptible to experimental cerebral malaria.

  4. Cannabigerol is able to counteract oxidative stress by activation of CB2 receptors. CB2 antagonist pre-treatment indeed blocked the protective effects of Cannabigerol in H2O2 stimulated macrophages, while CB1R (show CNR1 Antibodies) was not involved.

  5. Findings demonstrate that miR (show MLXIP Antibodies)-139 exerts a pathogenic effect in Alzheimer's disease by modulating CB2-meditated neuroinflammatory processes.

  6. Activation of CB2 ameliorates myocardial fibrosis via Nrf2 (show NFE2L2 Antibodies)-mediated inhibition of TGF-beta1 (show TGFB1 Antibodies)/Smad3 (show SMAD3 Antibodies) pathway in mice with myocardial infarction.

  7. This study provides insights into the role of CB2 cannabinoid receptors in regulating cognitive functions such as long-term memory.

  8. Behavioral assays revealed that hippocampus-dependent, long-term contextual fear memory was impaired whereas hippocampus-independent, cued fear memory was normal in CB2 receptor knockout mice. These mice also displayed enhanced spatial working memory when tested in a Y-maze.

  9. Data indicate that, in the mouse hippocampus, CB2R mRNAs are primarily expressed in a subset of excitatory and inhibitory neurons; amount of CB2R mRNAs in the mouse hippocampus is stable during postnatal development, from age 1 week to adulthood

  10. Findings indicate a physiologic role of type 2 cannabinoid receptor (CB2) in regulating the onset of meiosis and in maintaining the homeostasis of spermatogenesis.

CNR2 Antigen Profile

Protein Summary

The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors.

Gene names and symbols associated with CNR2

  • cannabinoid receptor 2 (macrophage) (CNR2) antibody
  • cannabinoid receptor 2 (cnr2) antibody
  • cannabinoid receptor 2 (macrophage) (Cnr2) antibody
  • CB-2 antibody
  • CB2 antibody
  • CB2-R antibody
  • cb2a antibody
  • cb2b antibody
  • CB2C antibody
  • CNR2 antibody
  • CNR2C antibody
  • CX5 antibody

Protein level used designations for CNR2

cannabinoid receptor 2 (macrophage) , cannabinoid receptor 2 , CB2R , cannabinoid receptor 2 type A , cannabinoid receptor-like cb2-zf , testis-dominant CNR2 isoform CB2 , CB2 receptor , peripheral cannabinoid receptor , rCB2 , cannabinoid receptor 2 (spleen)

GENE ID SPECIES
428232 Gallus gallus
456625 Pan troglodytes
539769 Bos taurus
612289 Canis lupus familiaris
795246 Danio rerio
1269 Homo sapiens
57302 Rattus norvegicus
12802 Mus musculus
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