Cannabinoid Receptor 2 Proteins (CNR2)

The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. Additionally we are shipping CNR2 Antibodies (134) and CNR2 Kits (14) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CNR2 1269 P34972
CNR2 57302 Q9QZN9
CNR2 12802 P47936
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Top CNR2 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$4,649.05
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
$6,616.87
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Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
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Wheat germ Human Un-conjugated   2 μg Log in to see 11 to 12 Days
$491.43
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Escherichia coli (E. coli) Human Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
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CNR2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Rat (Rattus)
Mouse (Murine) ,

More Proteins for Cannabinoid Receptor 2 (CNR2) Interaction Partners

Cow (Bovine) Cannabinoid Receptor 2 (CNR2) interaction partners

  1. Histological analyses revealed numerous endocrinal cell clusters or islets which were distributed among exocrine adenomeri in connectival tissue. Immunohistochemistry showed that endocrine-islets contained some CB2-positive cells with a very peculiar localization that is a few primarily localized at the edges of islets and some of them also scattered in the center of the cluster.

Zebrafish Cannabinoid Receptor 2 (CNR2) interaction partners

  1. genetic or chemical inhibition of cannabinoid receptor (Cnr (show PCDHA1 Proteins)) activity disrupts liver development and metabolic function in zebrafish.

  2. Cannabinoid Receptor-2 Regulates Embryonic Hematopoietic Stem Cell Development via Prostaglandin E2 and P-Selectin (show SELP Proteins) Activity.

  3. Activation of the Cnr2 receptor inhibits leukocyte migration in response to acute injury.

Human Cannabinoid Receptor 2 (CNR2) interaction partners

  1. stimulation of MAPK (show MAPK1 Proteins) contributes to the peripheral analgesic effect of CB2 receptor agonists.

  2. Describe PM226, a chromenoisoxazole, as a selective CB2 receptor agonist with neuroprotective properties.

  3. Our data indicate that CB2 may directly contribute to the pathogenesis of eosinophil-driven diseases. Moreover, we provide new insights into the molecular mechanisms underlying the CB2 -mediated priming of eosinophils.

  4. hepatic expression of CB1 (show CNR1 Proteins) and CB2 plays an important role during the progression of fibrosis induced by chronic hepatitis B

  5. analysis of the interplay between the CB2-RR variant and liver necroinflammation in chronic hepatitis patients with HIV/HCV coinfection

  6. Patients with schizophrenia showed increased CB2R expression in cells of the innate immune system and simpler correlation network between cytokines and CBRs expression when compared with controls.

  7. Data suggest that signaling via endocannabinoids and CNR1/CNR2 plays central role in food intake; the endocannabinoid system regulates bidirectional communication (in the context of energy intake and storage) between the brain and peripheral tissues (adipose tissue, liver, gastrointestinal tract, endocrine pancreas, and skeletal muscle). [REVIEW]

  8. Selective estrogen receptor (ER (show ESR1 Proteins)) modulator (SERM) isomers exhibit distinct affinity and selectivity for cannabinoid subtype 1 and 2 receptors (CB1R (show CNR1 Proteins) and CB2Rs).

  9. We investigated the relationship between variation in the CNR1 (show CNR1 Proteins), CNR2, and FAAH (show FAAH Proteins) genes and change in primary anxiety disorder severity. Five SNPs were nominally associated with a poorer treatment response (rs806365 [CNR1 (show CNR1 Proteins)]; rs2501431 [CNR2]; rs2070956 [CNR2]; rs7769940 [CNR1 (show CNR1 Proteins)]; rs2209172 [FAAH (show FAAH Proteins)]) and one with a more favorable response (rs6928813 [CNR1 (show CNR1 Proteins)]).

  10. Cannabinoid Receptor 2 mutation is associated with obesity.

Mouse (Murine) Cannabinoid Receptor 2 (CNR2) interaction partners

  1. Describe PM226, a chromenoisoxazole, as a selective CB2 receptor agonist with neuroprotective properties.

  2. LRRK2 (show LRRK2 Proteins) transgenic mice develop motor impairment and selective activation of CB2 receptor partially reversed the deficits.

  3. Given overlapping and complementary functions of CB1 (show CNR1 Proteins) and CB2 receptors, we queried whether double-knockout mice would show an exacerbated neurological phenotype

  4. this study shows that the expression of CB2 receptor in B-lymphocytes is differentially regulated during pregnancy

  5. Our data indicate that CB2 may directly contribute to the pathogenesis of eosinophil-driven diseases. Moreover, we provide new insights into the molecular mechanisms underlying the CB2 -mediated priming of eosinophils.

  6. CB2 receptor activation prevents degeneration of dopamine neurons in the the substantia nigra of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine - lesioned mice in vivo - a model of Parkinson's disease.

  7. activation of CB2R ameliorates DSS (show PMP22 Proteins)-induced colitis through enhancing autophagy that may inhibit NLRP3 (show NLRP3 Proteins) inflammasome activation in macrophages.

  8. Data show that (-)-beta-caryophyllene (BCP (show OPN1SW Proteins)) diminished axonal demyelination and modulated Th1 (show HAND1 Proteins)/Treg immune balance through the activation of cannabinoid receptor type 2 (CB2 receptor).

  9. Study demonstrated that the activation of CB2R attenuates the ocular pathology associated with the development and progression of experimental proliferative vitreoretinopathy; intervention at early stage proliferative vitreoretinopathy with CB2R agonists reduces ocular inflammation and disease severity.

  10. the M2 macrophage chemokine CCL17 was identified as an essential factor for enhanced survival in the absence of CB2, because CCL17 x Cnr2 double-deficient mice were fully susceptible to experimental cerebral malaria.

CNR2 Protein Profile

Protein Summary

The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors.

Gene names and symbols associated with Cannabinoid Receptor 2 Proteins (CNR2)

  • cannabinoid receptor 2 (CNR2)
  • cannabinoid receptor 2 (cnr2)
  • cannabinoid receptor 2 (Cnr2)
  • cannabinoid receptor 2 (macrophage) (Cnr2)
  • CB-2 protein
  • CB2 protein
  • CB2-R protein
  • cb2a protein
  • cb2b protein
  • CB2C protein
  • CNR2 protein
  • CNR2C protein
  • CX5 protein

Protein level used designations for Cannabinoid Receptor 2 Proteins (CNR2)

cannabinoid receptor 2 (macrophage) , cannabinoid receptor 2 , CB2R , cannabinoid receptor 2 type A , cannabinoid receptor-like cb2-zf , testis-dominant CNR2 isoform CB2 , CB2 receptor , peripheral cannabinoid receptor , rCB2 , cannabinoid receptor 2 (spleen)

GENE ID SPECIES
428232 Gallus gallus
456625 Pan troglodytes
539769 Bos taurus
612289 Canis lupus familiaris
795246 Danio rerio
1269 Homo sapiens
57302 Rattus norvegicus
12802 Mus musculus
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