COBRA1 Proteins
(Cofactor of BRCA1 (COBRA1))
NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2\; MIM 606026), either NELFC or NELFD (TH1L\; MIM 605297), and NELFE (RDBP\; MIM 154040). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1\; MIM 603555) and SPT5 (SUPT5H\; MIM 602102), to cause transcriptional pausing of RNA polymerase II (see MIM 180660) (Narita et al., 2003 [PubMed 12612062]).[supplied by OMIM, Mar 2008].
| Catalog no. | Product | Reactivity | Host / Clonality | Application | Price & lead time |
|---|---|---|---|---|---|
| COBRA1 Protein (AA 1-475) (GST tag) | Human | Wheat germ |
|
$475.39
View price
|
|
| COBRA1 Protein (AA 1-580) (Strep Tag) | Human | Cell-free protein synthesis (CFPS) |
|
starts at $19,692.86
View price
|
|
| COBRA1 Protein (AA 1-580) (Strep Tag) | Mouse | Cell-free protein synthesis (CFPS) |
|
starts at $19,692.86
View price
|
|
| COBRA1 Protein (AA 8-199, partial) (GST tag) | Human | Escherichia coli (E. coli) |
|
$493.16
View price
|
|
| COBRA1 Protein (Myc-DYKDDDDK Tag) | Human | HEK-293 Cells |
|
$956.40
View price
|
Protein
- AP (Affinity Purification: Listed application)
- AA (Antibody Array: Listed application)
- ELISA (ELISA: Listed application)
- WB (Western Blotting: Listed application)
- Origin
- Human
- Host
- Wheat germ
- Protein Type
- Recombinant
Catalog No. ABIN1349911
$475.39
Plus shipping costs $50.00, if applicable $20.00 dry ice
10 μg
(More quantities available)
Shipping to:
United States
Delivery in 11 to 14 Business Days
Protein
- ELISA (ELISA: Listed application)
- SDS (SDS-PAGE: Listed application)
- WB (Western Blotting: Listed application)
- Grade
- custom-made
- Origin
- Human
- Host
- Cell-free protein synthesis (CFPS)
- Protein Type
- Recombinant
- Purity
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Catalog No. ABIN3084252
starts at
$19,692.86
Plus shipping costs $50.00, if applicable $20.00 dry ice
250 μg
Shipping to:
United States
Delivery in 55 to 67 Business Days
Protein
- ELISA (ELISA: Listed application)
- SDS (SDS-PAGE: Listed application)
- WB (Western Blotting: Listed application)
- Grade
- custom-made
- Origin
- Mouse
- Host
- Cell-free protein synthesis (CFPS)
- Protein Type
- Recombinant
- Purity
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Catalog No. ABIN3125688
starts at
$19,692.86
Plus shipping costs $50.00, if applicable $20.00 dry ice
250 μg
Shipping to:
United States
Delivery in 55 to 67 Business Days
Protein
- SDS (SDS-PAGE: Validation image available)
- ELISA (ELISA: Listed application)
2 references - Origin
- Human
- Host
- Escherichia coli (E. coli)
- Protein Type
- Recombinant
- Purity
- 90 %
Catalog No. ABIN1047452
$493.16
Plus shipping costs $50.00
100 μg
(More quantities available)
Shipping to:
United States
Delivery in 13 to 17 Business Days
Protein
- WB (Western Blotting: Validation image available)
- AbP (Antibody Production: Listed application)
- STD (Standard: Listed application)
- Origin
- Human
- Host
- HEK-293 Cells
- Protein Type
- Recombinant
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Catalog No. ABIN2727090
$956.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
Shipping to:
United States
Delivery in 11 to 12 Business Days
Latest Publications for our COBRA1 Proteins
: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, (2003) (PubMed).
: "BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations." in: The Journal of cell biology, Vol. 155, Issue 6, pp. 911-21, (2001) (PubMed).
: "BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations." in: The Journal of cell biology, Vol. 155, Issue 6, pp. 911-21, (2001) (PubMed).
Aliases for COBRA1 Proteins
cofactor of BRCA1 (LOC100219583) Proteinsnegative elongation factor complex member B (NELFB) Proteins
negative elongation factor complex member B (nelfb) Proteins
negative elongation factor complex member B L homeolog (nelfb.L) Proteins
negative elongation factor complex member B (Nelfb) Proteins
A730008L03Rik Proteins
AB041607 Proteins
AI663983 Proteins
bZ1O1.4 Proteins
COBRA1 Proteins
cobra1 Proteins
Cobra1 Proteins
cobra2 Proteins
fe01e12 Proteins
LOC100219583 Proteins
MGC131073 Proteins
NELF-B Proteins
Nelf-b Proteins
RGD1307832 Proteins
wu:fe01e12 Proteins
zgc:55628 Proteins
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