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CCL2 is one of several cytokine genes clustered on the q-arm of chromosome 17. Additionally we are shipping Chemokine (C-C Motif) Ligand 2 Kits (164) and Chemokine (C-C Motif) Ligand 2 Proteins (130) and many more products for this protein.
Showing 10 out of 528 products:
Human Monoclonal CCL2 Primary Antibody for EIA - ABIN453918
Matsushima, Larsen, DuBois, Oppenheim: Purification and characterization of a novel monocyte chemotactic and activating factor produced by a human myelomonocytic cell line. in The Journal of experimental medicine 1989
Show all 9 references for ABIN453918
Cow (Bovine) Polyclonal CCL2 Primary Antibody for EIA, WB - ABIN401066
Liptak, Sullivan, Henkes, Wijayagunawardane, Miyamoto, Davis, Rueda, Townson: Cooperative expression of monocyte chemoattractant protein 1 within the bovine corpus luteum: evidence of immune cell-endothelial cell interactions in a coculture system. in Biology of reproduction 2005
Show all 3 references for ABIN401066
Mouse (Murine) Monoclonal CCL2 Primary Antibody for IHC (fro), IHC (p) - ABIN1108186
Zoja, Liu, Donadelli, Abbate, Testa, Corna, Taraboletti, Vecchi, Dong, Rollins, Bertani, Remuzzi: Renal expression of monocyte chemoattractant protein-1 in lupus autoimmune mice. in Journal of the American Society of Nephrology : JASN 1997
Show all 3 references for ABIN1108186
Human Monoclonal CCL2 Primary Antibody for EIA, FACS - ABIN1108180
Semple, Kossmann, Morganti-Kossmann: Role of chemokines in CNS health and pathology: a focus on the CCL2/CCR2 and CXCL8/CXCR2 networks. in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2010
Show all 2 references for ABIN1108180
Human Polyclonal CCL2 Primary Antibody for BP, ICC - ABIN446462
Fet, Fiebeler, Klinge, Park, Barth, Thepen, Tolba: Reduction of activated macrophages after ischaemia-reperfusion injury diminishes oxidative stress and ameliorates renal damage. in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2012
Show all 2 references for ABIN446462
Human Polyclonal CCL2 Primary Antibody for EIA, IHC (p) - ABIN452821
Rollins, Morton, Ledbetter, Eddy, Shows: Assignment of the human small inducible cytokine A2 gene, SCYA2 (encoding JE or MCP-1), to 17q11.2-12: evolutionary relatedness of cytokines clustered at the same locus. in Genomics 1991
Show all 2 references for ABIN452821
Mouse (Murine) Polyclonal CCL2 Primary Antibody for Neut, WB - ABIN223560
Lau, Liu, Pahlevan, Yuan, Khazaeli, Ni, Chan, Vaziri: Role of Nrf2 Dysfunction in Uremia-Associated Intestinal Inflammation and Epithelial Barrier Disruption. in Digestive diseases and sciences 2014
Human Polyclonal CCL2 Primary Antibody for WB - ABIN446454
Xiang, Dong, Liu, Wang, Shi, Wei, Hu, Gong: Inhibitory effects of suppressor of cytokine signaling 3 on inflammatory cytokine expression and migration and proliferation of IL-6/IFN-?-induced vascular smooth muscle cells. in Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2013
Human Polyclonal CCL2 Primary Antibody for FACS, IF - ABIN390653
Bannon, Johnson, Michelhaugh, Hartley, Halter, David, Kapatos, Schmidt: A molecular profile of cocaine abuse includes the differential expression of genes that regulate transcription, chromatin, and dopamine cell phenotype. in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2014
Dog (Canine) Polyclonal CCL2 Primary Antibody for IHC, WB - ABIN2792200
Carulli, Spagnolo, Fonseca, Welsh, duBois, Black, Denton: Single-nucleotide polymorphisms in CCL2 gene are not associated with susceptibility to systemic sclerosis. in The Journal of rheumatology 2008
MCP-1, MIP-1beta (show CCL4 Antibodies), and IP-10 (show CXCL10 Antibodies) may modify the pathologic features of Rhegmatogenous Retinal Detachment.
This meta-analysis demonstrates that the MCP-1 -2518 A/G polymorphism is not associated with susceptibility to vasculitis, rheumatoid arthritis, and multiple sclerosis.
Results of this study indicated that the CCL2-CCR2 axis was involved in the pathogenesis of oral lichen planus and was positively correlated with disease activity.
In scleroderma patients MCP-1 was the prominent biomarker correlated with the manifestations related to fibrosis, disease activity score and severity of pulmonary involvement.
MCP1 levels in the serum of patients with SGT (show SGTA Antibodies) were decreased.
AG genotype of CCL2-2518 in combination with TT genotype of CFH (show CFH Antibodies) Y402H showed significant protective effect against age-related macular degeneration.
Ang III (show AGT Antibodies) increases MCP-1 synthesis via stimulation of intracellular p38 (show CRK Antibodies) and JNK (show MAPK8 Antibodies) MAPK (show MAPK1 Antibodies) signaling activity and subsequent activated protein-1 transcriptional activity in proximal kidney tubule cells.
Monocytic MCP-1 gene expression was found to be increased significantly in severe OSA patients
High circulating CCL2 levels are associated with overweight and obesity.
Serum MCP-1 does not differentiate between recurrent acute pancreatitis and chronic pancreatitis.
study suggests that MCP-1 (show CPT1B Antibodies) might promote intracerebral hemorrhage-induced microglia activation and toxicity to neurons
Results show that CCL2 from astrocytes selectively induces microglial activation associated with M1 polarization and enhanced migration ability.
kiss1 (show KISS1 Antibodies) and kiss1r (show KISS1R Antibodies) mRNA levels were significantly higher in old compared to reproductive-aged mice, and diet-induced obesity did not alter kiss1 (show KISS1 Antibodies) or kiss1r (show KISS1R Antibodies) mRNA levels. Compared to young control mice, young MCP-1 (show CPT1B Antibodies) knockout mice had significantly lower ovarian kiss1 (show KISS1 Antibodies) mRNA
In 3T3-L1 preadipocytes, Ad36, but not E4orf1, increased MCP1 and TNFalpha (show TNF Antibodies) mRNA, in presence of LPS (show TLR4 Antibodies) stimulation.
Probiotic Lactobacillus reuteri can prevent the exacerbating effects of stressor exposure on Citrobacter-induced colitis; one mechanism by which this occurs is through downregulation of the chemokine (show CCL1 Antibodies) CCL2.
CCL2 and its receptor CCR2 are important for the formation of osteoclasts and foreign body giant cells.
FAMP significantly preserved cytochrome C (show CYCS Antibodies) in the mitochondrial fraction and inhibited its release into the cytosolic fraction in the heart, but did not significantly reduce mRNA levels of monocyte chemoattractant protein-1
Mycobacterium chelonae activates the gene expressions of chemokine (C-C motif) ligand 2 (CCL2) and CCL5 (show CCL5 Antibodies) in murine bone marrow-derived macrophages and in vivo mouse model.
This study demonstrated that Chemokine (show CCL1 Antibodies) CCL2 Mediates the Seizure-enhancing Effects of Systemic Inflammation.
cl2 (show DCLK2 Antibodies) mRNAs increased within 5 h after injury in mouse cortical slices.
resence of type 2 diabetes negatively affects the work of cytokines and markers of fibrosis, as evidenced by higher levels of interleukin-1beta and monocyte chemoattractant protein-1, compared with patients without diabetes
Studied SNPs in the bovine toll-like receptor 4 (TLR4 (show TLR4 Antibodies)) and monocyte chemo attractant protein-1(CCL2) genes.
The LEP (show LEP Antibodies), IGF2 and CCL2 genes showed allelic expression imbalance in liver, kidney and pituitary glands of Polish Holstein-Friesian bulls.
immune cells and endothelial cells can interact cooperatively to increase CCL2 secretion in the corpus luteum
Data show that peripheral blood endothelial progenitor cells can increase the expressions of chemokines CCL2 and CXCL12 (show CXCL12 Antibodies) and promote the migration of enhanced green fluorescent protein-positive bone marrow stromal cells to bone defect site.
In a cerebral aneurysm, expression of MCP1 peaked after induction for one week, then decreased. MCP1 induced macrophage adhesion and infiltration in the artery wall of aneurysms, and contributed to the occurrence and development of brain aneurysm.
Data show that the serum levels of mast cell tryptase, monocyte chemoattractant protein-1 (MCP-1) and interleukin-8 (IL-8 (show IL8 Antibodies)) decreased significantly in Dachengqi decoction treatment group.
measurements of CCL2 and macrophages can serve as new inflammatory biomarkers to evaluate the safety of promising novel microbicides for prevention of HIV.
Expression of MCP-1 was successfully inhibited by transfecting MCP-1 siRNA expression plasmid to the carotid artery, and the progression of atherosclerosis was restricted by RNAi-mediated silencing of MCP-1 expression.
CXCL10 (show CXCL10 Antibodies) protein was detected in serum from pigs infected with a high virulence African swine fever virus isolate. Levels of CCL2 mRNA were increased in pigs infected with the high virulence isolate compared to a low virulence isolate.
Porcine CCL2 binding on Tuk4+SLA (show SLA Antibodies)-II- but not on Tuk4-SLA (show SLA Antibodies)-II+ cells was detected by using a CCL2-green fluorescence protein fusion protein.
The protective properties of flavonoids, such as EGCG, against endothelial inflammation may be regulated in part though induction of HO-1 and subsequent activator protein-1 signaling.
MCP-1 contributes to functional and structural impairment in the kidney in renal artery stenosis, mainly in the tubulointerstitial compartment
Contrast media did not affect bone marrow cell viability/MCP-1 secretion.
Porcine vessel wall injury via balloon arthroplasty upregulates expression of CCL2 by coronary artery transmural and perivascular cells in a sequential pattern.
in the aortic arch expression of monocyte chemoattractant protein 1 (MCP-1) was upregulated, compared with the thoracic aorta
Variable gene expression (eg, matrix metalloproteinase-9 (show MMP9 Antibodies), CCL2 and Lp-PLA(2 (show Lp-PLA2 Antibodies)) mRNAs), both in regard to the arterial bed and duration of disease, was associated with variable plaque development and progression.
myocardial infarction induced proinflammatory gene and protein expression in peripheral blood mononuclear cells of tissue factor (show F3 Antibodies) cyclo-oxygenase-2, monocyte chemoattractant protein-1 and CRP (show CRP Antibodies)
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
small inducible cytokine A2
, C-C motif chemokine 2
, immediate-early serum-responsive JE protein
, immediate-early serum-responsive protein JE
, monocyte chemoattractant protein 1
, monocyte chemoattractant protein-1
, monocyte chemotactic protein 1
, small inducible gene JE
, small-inducible cytokine A2
, monocyte chemotactic and activating factor
, monocyte secretory protein JE
, small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je)
, small inducible cytokine subfamily A (Cys-Cys), member 2
, platelet-derived growth factor-inducible protein JE
, acidic seminal fluid protein
, monocyte chemotactic protein 1A
, chemokine CCL2/MCP-1
, antiadrenocorticotropin peptide III
, corticostatin III
, macrophage antibiotic peptide MCP-1
, mast cell protease 1A