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anti-Chemokine (C-C Motif) Ligand 2 (CCL2) Antibodies

CCL2 is one of several cytokine genes clustered on the q-arm of chromosome 17. Additionally we are shipping Chemokine (C-C Motif) Ligand 2 Kits (165) and Chemokine (C-C Motif) Ligand 2 Proteins (127) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CCL2 24770 P14844
CCL2 6347 P13500
CCL2 20296 P10148
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Top anti-Chemokine (C-C Motif) Ligand 2 Antibodies at

Showing 10 out of 550 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Western blot analysis of CCL2 Antibody (C-term) (ABIN390653) in Hela cell line lysates (35 µg/lane). CCL2 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue with CCL2 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
Dog Rabbit Un-conjugated IHC, WB WB Suggested Anti-CCL2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Transfected 293T Sample Type: Human Macrophange CellsGreen: primaryRed: phallodinBlue: DAPIYellow: green/redPrimary Dilution: 1:200Secondary Antibody: anti-Rabbit IgG-FITCSecondary Dilution: 1:1000Image Submitted By: Milan FialaUniversity of California, Los Angeles 100 μL Log in to see 2 to 3 Days
Mouse Rat Un-conjugated IHC (fro), IHC (p), WB   0.1 mg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated WB Western Blot: CCL2/MCP1 Antibody [NBP1-07034] - Analysis of recombinant mouse MCP1. Image provided via product review by verified customer. 0.1 mL Log in to see 5 to 7 Days
Human Rabbit Un-conjugated BP, ICC, IF, IHC, IHC (fro), Neut, WB Immunocytochemistry/Immunofluorescence: CCL2/MCP1 Antibody [NBP1-07035] - MCP1 antibody was tested in HeLa cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). 0.1 mL Log in to see 5 to 7 Days
Human Mouse Un-conjugated EIA, FACS, IF, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
Cow Rabbit Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
Human Mouse HRP EIA   0.2 mL Log in to see 6 to 8 Days
Mouse Rabbit Un-conjugated Neut, WB Western blot analysis of MCP-1 in LPS treated RAW cell lysate. 100 μg Log in to see 2 to 3 Days

CCL2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Chemokine (C-C Motif) Ligand 2 Antibodies

  1. Human Monoclonal CCL2 Primary Antibody for EIA - ABIN453918 : Matsushima, Larsen, DuBois, Oppenheim: Purification and characterization of a novel monocyte chemotactic and activating factor produced by a human myelomonocytic cell line. in The Journal of experimental medicine 1989 (PubMed)
    Show all 9 references for ABIN453918

  2. Cow (Bovine) Polyclonal CCL2 Primary Antibody for EIA, WB - ABIN401066 : Liptak, Sullivan, Henkes, Wijayagunawardane, Miyamoto, Davis, Rueda, Townson: Cooperative expression of monocyte chemoattractant protein 1 within the bovine corpus luteum: evidence of immune cell-endothelial cell interactions in a coculture system. in Biology of reproduction 2005 (PubMed)
    Show all 3 references for ABIN401066

  3. Mouse (Murine) Monoclonal CCL2 Primary Antibody for IHC (fro), IHC (p) - ABIN1108186 : Zoja, Liu, Donadelli, Abbate, Testa, Corna, Taraboletti, Vecchi, Dong, Rollins, Bertani, Remuzzi: Renal expression of monocyte chemoattractant protein-1 in lupus autoimmune mice. in Journal of the American Society of Nephrology : JASN 1997 (PubMed)
    Show all 3 references for ABIN1108186

  4. Human Monoclonal CCL2 Primary Antibody for EIA, FACS - ABIN1108180 : Semple, Kossmann, Morganti-Kossmann: Role of chemokines in CNS health and pathology: a focus on the CCL2/CCR2 and CXCL8/CXCR2 networks. in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2010 (PubMed)
    Show all 2 references for ABIN1108180

  5. Human Polyclonal CCL2 Primary Antibody for BP, ICC - ABIN446462 : Fet, Fiebeler, Klinge, Park, Barth, Thepen, Tolba: Reduction of activated macrophages after ischaemia-reperfusion injury diminishes oxidative stress and ameliorates renal damage. in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2012 (PubMed)
    Show all 2 references for ABIN446462

  6. Human Polyclonal CCL2 Primary Antibody for EIA, IHC (p) - ABIN452821 : Rollins, Morton, Ledbetter, Eddy, Shows: Assignment of the human small inducible cytokine A2 gene, SCYA2 (encoding JE or MCP-1), to 17q11.2-12: evolutionary relatedness of cytokines clustered at the same locus. in Genomics 1991 (PubMed)
    Show all 2 references for ABIN452821

  7. Mouse (Murine) Polyclonal CCL2 Primary Antibody for Neut, WB - ABIN223560 : Lau, Liu, Pahlevan, Yuan, Khazaeli, Ni, Chan, Vaziri: Role of Nrf2 Dysfunction in Uremia-Associated Intestinal Inflammation and Epithelial Barrier Disruption. in Digestive diseases and sciences 2014 (PubMed)

  8. Human Polyclonal CCL2 Primary Antibody for WB - ABIN446454 : Xiang, Dong, Liu, Wang, Shi, Wei, Hu, Gong: Inhibitory effects of suppressor of cytokine signaling 3 on inflammatory cytokine expression and migration and proliferation of IL-6/IFN-?-induced vascular smooth muscle cells. in Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2013 (PubMed)

  9. Human Polyclonal CCL2 Primary Antibody for FACS, IF - ABIN390653 : Bannon, Johnson, Michelhaugh, Hartley, Halter, David, Kapatos, Schmidt: A molecular profile of cocaine abuse includes the differential expression of genes that regulate transcription, chromatin, and dopamine cell phenotype. in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2014 (PubMed)

  10. Dog (Canine) Polyclonal CCL2 Primary Antibody for IHC, WB - ABIN2792200 : Carulli, Spagnolo, Fonseca, Welsh, duBois, Black, Denton: Single-nucleotide polymorphisms in CCL2 gene are not associated with susceptibility to systemic sclerosis. in The Journal of rheumatology 2008 (PubMed)

More Antibodies against Chemokine (C-C Motif) Ligand 2 Interaction Partners

Human Chemokine (C-C Motif) Ligand 2 (CCL2) interaction partners

  1. the sensitivity and specificity of CEA (show CEACAM5 Antibodies), CA125 (show MUC16 Antibodies), and ProGRP when used in combination with IL-6 (show IL6 Antibodies), IL-10 (show IL10 Antibodies), and MCP (show CD46 Antibodies) in lung cancer diagnosis, was examined.

  2. CCL2 and CXCL10 (show CXCL10 Antibodies) play important roles in the progression of obesity-related metabolic complications in children.

  3. urinary MCP-1 correlates well with lupus nephritis disease activity and helps differentiate between active nephritis and active disease without nephritis patients.

  4. Data show that high intratumor C-C motif ligand 2 (CCL2)expression associated with adverse clinical outcome.

  5. This meta-analysis showed that the MCP-1-2518-A allele confers susceptibility to Asian patients with rheumatoid arthritis and European patients with Crohn's disease.

  6. HUMSCs expressing ISZ-sTRAIL might be an efficient therapeutic approach against lung cancer and MCP-1/CCR2 axis is essential for the tumor tropism of HUMSCs

  7. MCP-1 appeared to be independently related to a measure of adiposity in a cohort of obese patients from Iran.

  8. High MCP1 level is associated with hypertriglyceridemia.

  9. MCP-1, MIP-1beta (show CCL4 Antibodies), and IP-10 (show CXCL10 Antibodies) may modify the pathologic features of Rhegmatogenous Retinal Detachment.

  10. This meta-analysis demonstrates that the MCP-1 -2518 A/G polymorphism is not associated with susceptibility to vasculitis, rheumatoid arthritis, and multiple sclerosis.

Mouse (Murine) Chemokine (C-C Motif) Ligand 2 (CCL2) interaction partners

  1. Data show that RP105 (show GPR83 Antibodies) knockout (-/-) smooth muscle cells and mast cells secreted higher levels of chemokine (C-C motif) ligand 2 protein (CCL2).

  2. CCL2/CCL3 (show CCL3 Antibodies) double-mutant animals are viable, fertile, and do not present with gross abnormalities. Cuprizone increased CCL2 expression in wild-type but not mutant miCuprizone-induced demyelination, oligodendrocyte loss, and astrogliosis were significantly ameliorated in the cortex but not corpus callosum of chemokine (show CCL1 Antibodies)-deficient animals.

  3. study suggests that MCP-1 (show CPT1B Antibodies) might promote intracerebral hemorrhage-induced microglia activation and toxicity to neurons

  4. Results show that CCL2 from astrocytes selectively induces microglial activation associated with M1 polarization and enhanced migration ability.

  5. kiss1 (show KISS1 Antibodies) and kiss1r (show KISS1R Antibodies) mRNA levels were significantly higher in old compared to reproductive-aged mice, and diet-induced obesity did not alter kiss1 (show KISS1 Antibodies) or kiss1r (show KISS1R Antibodies) mRNA levels. Compared to young control mice, young MCP-1 (show CPT1B Antibodies) knockout mice had significantly lower ovarian kiss1 (show KISS1 Antibodies) mRNA

  6. In 3T3-L1 preadipocytes, Ad36, but not E4orf1, increased MCP1 and TNFalpha (show TNF Antibodies) mRNA, in presence of LPS (show TLR4 Antibodies) stimulation.

  7. Probiotic Lactobacillus reuteri can prevent the exacerbating effects of stressor exposure on Citrobacter-induced colitis; one mechanism by which this occurs is through downregulation of the chemokine (show CCL1 Antibodies) CCL2.

  8. CCL2 and its receptor CCR2 are important for the formation of osteoclasts and foreign body giant cells.

  9. FAMP significantly preserved cytochrome C (show CYCS Antibodies) in the mitochondrial fraction and inhibited its release into the cytosolic fraction in the heart, but did not significantly reduce mRNA levels of monocyte chemoattractant protein-1

  10. Mycobacterium chelonae activates the gene expressions of chemokine (C-C motif) ligand 2 (CCL2) and CCL5 (show CCL5 Antibodies) in murine bone marrow-derived macrophages and in vivo mouse model.

Cow (Bovine) Chemokine (C-C Motif) Ligand 2 (CCL2) interaction partners

  1. resence of type 2 diabetes negatively affects the work of cytokines and markers of fibrosis, as evidenced by higher levels of interleukin-1beta and monocyte chemoattractant protein-1, compared with patients without diabetes

  2. Studied SNPs in the bovine toll-like receptor 4 (TLR4 (show TLR4 Antibodies)) and monocyte chemo attractant protein-1(CCL2) genes.

  3. The LEP (show LEP Antibodies), IGF2 and CCL2 genes showed allelic expression imbalance in liver, kidney and pituitary glands of Polish Holstein-Friesian bulls.

  4. immune cells and endothelial cells can interact cooperatively to increase CCL2 secretion in the corpus luteum

Rabbit Chemokine (C-C Motif) Ligand 2 (CCL2) interaction partners

  1. Data show that peripheral blood endothelial progenitor cells can increase the expressions of chemokines CCL2 and CXCL12 (show CXCL12 Antibodies) and promote the migration of enhanced green fluorescent protein-positive bone marrow stromal cells to bone defect site.

  2. In a cerebral aneurysm, expression of MCP1 peaked after induction for one week, then decreased. MCP1 induced macrophage adhesion and infiltration in the artery wall of aneurysms, and contributed to the occurrence and development of brain aneurysm.

  3. Data show that the serum levels of mast cell tryptase, monocyte chemoattractant protein-1 (MCP-1) and interleukin-8 (IL-8 (show IL8 Antibodies)) decreased significantly in Dachengqi decoction treatment group.

  4. measurements of CCL2 and macrophages can serve as new inflammatory biomarkers to evaluate the safety of promising novel microbicides for prevention of HIV.

  5. Expression of MCP-1 was successfully inhibited by transfecting MCP-1 siRNA expression plasmid to the carotid artery, and the progression of atherosclerosis was restricted by RNAi-mediated silencing of MCP-1 expression.

Pig (Porcine) Chemokine (C-C Motif) Ligand 2 (CCL2) interaction partners

  1. CXCL10 (show CXCL10 Antibodies) protein was detected in serum from pigs infected with a high virulence African swine fever virus isolate. Levels of CCL2 mRNA were increased in pigs infected with the high virulence isolate compared to a low virulence isolate.

  2. Porcine CCL2 binding on Tuk4+SLA (show SLA Antibodies)-II- but not on Tuk4-SLA (show SLA Antibodies)-II+ cells was detected by using a CCL2-green fluorescence protein fusion protein.

  3. The protective properties of flavonoids, such as EGCG, against endothelial inflammation may be regulated in part though induction of HO-1 and subsequent activator protein-1 signaling.

  4. MCP-1 contributes to functional and structural impairment in the kidney in renal artery stenosis, mainly in the tubulointerstitial compartment

  5. Contrast media did not affect bone marrow cell viability/MCP-1 secretion.

  6. Porcine vessel wall injury via balloon arthroplasty upregulates expression of CCL2 by coronary artery transmural and perivascular cells in a sequential pattern.

  7. in the aortic arch expression of monocyte chemoattractant protein 1 (MCP-1) was upregulated, compared with the thoracic aorta

  8. Variable gene expression (eg, matrix metalloproteinase-9 (show MMP9 Antibodies), CCL2 and Lp-PLA(2 (show Lp-PLA2 Antibodies)) mRNAs), both in regard to the arterial bed and duration of disease, was associated with variable plaque development and progression.

  9. myocardial infarction induced proinflammatory gene and protein expression in peripheral blood mononuclear cells of tissue factor (show F3 Antibodies) cyclo-oxygenase-2, monocyte chemoattractant protein-1 and CRP (show CRP Antibodies)

Chemokine (C-C Motif) Ligand 2 (CCL2) Antigen Profile

Protein Summary

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.

Gene names and symbols associated with CCL2

  • chemokine (C-C motif) ligand 2 (CCL2) antibody
  • chemokine (C-C motif) ligand 2 (Ccl2) antibody
  • macrophage cationic peptide 1 (MCP-1) antibody
  • mast cell proteinase-1 (MCP1) antibody
  • AI323594 antibody
  • GDCF-2 antibody
  • HC11 antibody
  • HSMCR30 antibody
  • JE antibody
  • MCAF antibody
  • MCP-1 antibody
  • MCP-1A antibody
  • MCP1 antibody
  • MCP1A antibody
  • SCYA2 antibody
  • Sigje antibody
  • SMC-CF antibody

Protein level used designations for CCL2

small inducible cytokine A2 , C-C motif chemokine 2 , immediate-early serum-responsive JE protein , immediate-early serum-responsive protein JE , monocyte chemoattractant protein 1 , monocyte chemoattractant protein-1 , monocyte chemotactic protein 1 , small inducible gene JE , small-inducible cytokine A2 , monocyte chemotactic and activating factor , monocyte secretory protein JE , small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je) , small inducible cytokine subfamily A (Cys-Cys), member 2 , platelet-derived growth factor-inducible protein JE , acidic seminal fluid protein , monocyte chemotactic protein 1A , MCP-1 , chemokine CCL2/MCP-1 , CS-III , NP-1 , antiadrenocorticotropin peptide III , corticostatin III , corticostatin-3 , macrophage antibiotic peptide MCP-1 , SMCP-1A , mast cell protease 1A

748205 Pan troglodytes
24770 Rattus norvegicus
6347 Homo sapiens
20296 Mus musculus
281043 Bos taurus
100009130 Oryctolagus cuniculus
397422 Sus scrofa
403981 Canis lupus familiaris
100135494 Cavia porcellus
100034136 Equus caballus
100172740 Pongo abelii
101120093 Ovis aries
574138 Macaca mulatta
100009115 Oryctolagus cuniculus
443546 Ovis aries
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