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anti-Chemokine (C-C Motif) Ligand 2 (CCL2) Antibodies

CCL2 is one of several cytokine genes clustered on the q-arm of chromosome 17. Additionally we are shipping Chemokine (C-C Motif) Ligand 2 Kits (167) and Chemokine (C-C Motif) Ligand 2 Proteins (128) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CCL2 24770 P14844
CCL2 6347 P13500
CCL2 20296 P10148
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Top anti-Chemokine (C-C Motif) Ligand 2 Antibodies at

Showing 10 out of 529 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Western blot analysis of CCL2 Antibody (C-term) (ABIN390653) in Hela cell line lysates (35 µg/lane). CCL2 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue with CCL2 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
Dog Rabbit Un-conjugated IHC, WB WB Suggested Anti-CCL2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Transfected 293T Sample Type: Human Macrophange CellsGreen: primaryRed: phallodinBlue: DAPIYellow: green/redPrimary Dilution: 1:200Secondary Antibody: anti-Rabbit IgG-FITCSecondary Dilution: 1:1000Image Submitted By: Milan FialaUniversity of California, Los Angeles 100 μL Log in to see 2 to 3 Days
Mouse Rat Un-conjugated IHC (fro), IHC (p), WB   0.1 mg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated WB 0.1 mL Log in to see 5 to 7 Days
Human Rabbit Un-conjugated BP, ICC, IF, IHC, IHC (fro), Neut, WB 0.1 mL Log in to see 5 to 7 Days
Human Mouse Un-conjugated EIA, FACS, IF, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
Cow Rabbit Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
Mouse Rabbit Un-conjugated Neut, WB Western blot analysis of MCP-1 in LPS treated RAW cell lysate. 100 μg Log in to see 2 to 3 Days
Human Mouse HRP EIA   0.2 mL Log in to see 6 to 8 Days

CCL2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Chemokine (C-C Motif) Ligand 2 Antibodies

  1. Cow (Bovine) Polyclonal CCL2 Primary Antibody for EIA, WB - ABIN401066 : Liptak, Sullivan, Henkes, Wijayagunawardane, Miyamoto, Davis, Rueda, Townson: Cooperative expression of monocyte chemoattractant protein 1 within the bovine corpus luteum: evidence of immune cell-endothelial cell interactions in a coculture system. in Biology of reproduction 2005 (PubMed)
    Show all 3 references for ABIN401066

  2. Mouse (Murine) Polyclonal CCL2 Primary Antibody for IF (p), IHC (p) - ABIN737676 : Guo, Feng, Yao, Sun, Zhu: Transplantation of endothelial progenitor cells in treating rats with IgA nephropathy. in BMC nephrology 2014 (PubMed)
    Show all 3 references for ABIN737676

  3. Mouse (Murine) Monoclonal CCL2 Primary Antibody for IHC (fro), IHC (p) - ABIN1108186 : Zoja, Liu, Donadelli, Abbate, Testa, Corna, Taraboletti, Vecchi, Dong, Rollins, Bertani, Remuzzi: Renal expression of monocyte chemoattractant protein-1 in lupus autoimmune mice. in Journal of the American Society of Nephrology : JASN 1997 (PubMed)
    Show all 3 references for ABIN1108186

  4. Human Monoclonal CCL2 Primary Antibody for EIA, FACS - ABIN1108180 : Semple, Kossmann, Morganti-Kossmann: Role of chemokines in CNS health and pathology: a focus on the CCL2/CCR2 and CXCL8/CXCR2 networks. in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2010 (PubMed)
    Show all 2 references for ABIN1108180

  5. Human Polyclonal CCL2 Primary Antibody for BP, ICC - ABIN446462 : Fet, Fiebeler, Klinge, Park, Barth, Thepen, Tolba: Reduction of activated macrophages after ischaemia-reperfusion injury diminishes oxidative stress and ameliorates renal damage. in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2012 (PubMed)
    Show all 2 references for ABIN446462

  6. Human Polyclonal CCL2 Primary Antibody for EIA, IHC (p) - ABIN452821 : Rollins, Morton, Ledbetter, Eddy, Shows: Assignment of the human small inducible cytokine A2 gene, SCYA2 (encoding JE or MCP-1), to 17q11.2-12: evolutionary relatedness of cytokines clustered at the same locus. in Genomics 1991 (PubMed)
    Show all 2 references for ABIN452821

  7. Mouse (Murine) Polyclonal CCL2 Primary Antibody for Neut, WB - ABIN223560 : Lau, Liu, Pahlevan, Yuan, Khazaeli, Ni, Chan, Vaziri: Role of Nrf2 Dysfunction in Uremia-Associated Intestinal Inflammation and Epithelial Barrier Disruption. in Digestive diseases and sciences 2014 (PubMed)

  8. Human Polyclonal CCL2 Primary Antibody for WB - ABIN446454 : Xiang, Dong, Liu, Wang, Shi, Wei, Hu, Gong: Inhibitory effects of suppressor of cytokine signaling 3 on inflammatory cytokine expression and migration and proliferation of IL-6/IFN-?-induced vascular smooth muscle cells. in Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2013 (PubMed)

  9. Human Polyclonal CCL2 Primary Antibody for FACS, IF - ABIN390653 : Bannon, Johnson, Michelhaugh, Hartley, Halter, David, Kapatos, Schmidt: A molecular profile of cocaine abuse includes the differential expression of genes that regulate transcription, chromatin, and dopamine cell phenotype. in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2014 (PubMed)

  10. Dog (Canine) Polyclonal CCL2 Primary Antibody for IHC, WB - ABIN2792200 : Carulli, Spagnolo, Fonseca, Welsh, duBois, Black, Denton: Single-nucleotide polymorphisms in CCL2 gene are not associated with susceptibility to systemic sclerosis. in The Journal of rheumatology 2008 (PubMed)

More Antibodies against Chemokine (C-C Motif) Ligand 2 Interaction Partners

Human Chemokine (C-C Motif) Ligand 2 (CCL2) interaction partners

  1. immunosensor allowed the rapid detection of MCP-1 in buffer and spiked human serum samples. An almost 2 order of magnitude linear range was observed, between 84.3 and 1582.1pg/mL and the limits of blank and detection were determined to be 0.3 and 0.5pg/mL, respectively

  2. Results indicate that urinary MCP-1 was associated with blood pressure elevation in this population of obese young adults.

  3. our data confirmed the relevance of the MCP1 gene as a risk locus to Pott's disease in a trans-populational manner.

  4. genetic association study in population in China: Data suggest higher frequency of GG genotype/G allele in -2518 SNP in MCP1 is observed in diabetes type 2 (DT2) with proliferative/non-proliferative retinopathies as compared with DT2 without retinopathy.

  5. the MCP1-induced cortactin (show CTTN Antibodies) phosphorylation is dependent on PLCbeta3-mediated PKCdelta (show PKCd Antibodies) activation, and siRNA-mediated down-regulation of either of these molecules prevents cortactin (show CTTN Antibodies) interaction with WAVE2 (show WASF2 Antibodies)

  6. MCP-1-2518 A/G polymorphism is associated with increased risk to breast cancer.

  7. Data show that monocytes from elderly denture wearers with Candida-related denture stomatitis produced lower levels of proinflammatory cytokines CXCL-8 (show IL8 Antibodies), IL-6 (show IL6 Antibodies) and MCP-1.

  8. CCL2 downregulation in South Asians may be an attempt to protect muscle against macrophage infiltration, and defects in fatty acid partitioning to muscle may lead to the disproportionate adiposity and adverse cardiometabolic profile in South Asians.

  9. R/R genotype of FCGR2A (show FCGR2A Antibodies) p.R131H and G/G genotype of CCL2 c.-2518 A > G polymorphisms are associated with thrombocytopenia, which is a characteristic laboratory finding in dengue infections.

  10. Together, these findings suggest that CCL2, RARRES2 (show RARRES2 Antibodies) and EFNB2 (show EFNB2 Antibodies) are host cell factors involved in respiratory syncytial virus replication.

Mouse (Murine) Chemokine (C-C Motif) Ligand 2 (CCL2) interaction partners

  1. FAMP significantly preserved cytochrome C (show CYCS Antibodies) in the mitochondrial fraction and inhibited its release into the cytosolic fraction in the heart, but did not significantly reduce mRNA levels of monocyte chemoattractant protein-1

  2. Mycobacterium chelonae activates the gene expressions of chemokine (C-C motif) ligand 2 (CCL2) and CCL5 (show CCL5 Antibodies) in murine bone marrow-derived macrophages and in vivo mouse model.

  3. This study demonstrated that Chemokine (show CCL1 Antibodies) CCL2 Mediates the Seizure-enhancing Effects of Systemic Inflammation.

  4. cl2 (show DCLK2 Antibodies) mRNAs increased within 5 h after injury in mouse cortical slices.

  5. Data show that cathepsins S (CatS) regulates CCL2 chemokine (show CCL1 Antibodies) expression by modulation of CD74 (show CD74 Antibodies) antigen processing.

  6. Data show that monocyte chemotactic protein 1 (MCP-1) expressed by HEK293T cells could apparently increase the migration of macrophages.

  7. Data indicate that Zoledronic acid (ZA) decreased mesenchymal stem cells (MSC (show MSC Antibodies))-monocyte chemotactic protein 1 (MCP-1) and therefore reduced the recruitment of tumor-associated macrophages (TAMs) to the tumor sites and hence inhibited the tumor growth.

  8. activation of canonical Wnt (show WNT2 Antibodies) signaling might contribute to the focal retinal degeneration of mouse models with Ccl2 and Cx3cr1 (show CX3CR1 Antibodies) deficiency

  9. Genetically modified mice overexpressing a human PS1 (show PSEN1 Antibodies) familial Alzheimer's disease mutant on a CCL2 null background significantly decreased hippocampal neurogenesis and affected age-dependent learning and memory.

  10. Given the important role of the TAM (show CCNA1 Antibodies) phenotype in the tumor microenvironment, inhibitory effect of luteolin on the monocyte recruitment and cancer migration via suppression of the TAM (show CCNA1 Antibodies)-secreted CCL2 suggests a novel therapeutic approach to treat tumors.

Cow (Bovine) Chemokine (C-C Motif) Ligand 2 (CCL2) interaction partners

  1. resence of type 2 diabetes negatively affects the work of cytokines and markers of fibrosis, as evidenced by higher levels of interleukin-1beta and monocyte chemoattractant protein-1, compared with patients without diabetes

  2. Studied SNPs in the bovine toll-like receptor 4 (TLR4 (show TLR4 Antibodies)) and monocyte chemo attractant protein-1(CCL2) genes.

  3. The LEP (show LEP Antibodies), IGF2 and CCL2 genes showed allelic expression imbalance in liver, kidney and pituitary glands of Polish Holstein-Friesian bulls.

  4. immune cells and endothelial cells can interact cooperatively to increase CCL2 secretion in the corpus luteum

Rabbit Chemokine (C-C Motif) Ligand 2 (CCL2) interaction partners

  1. Data show that peripheral blood endothelial progenitor cells can increase the expressions of chemokines CCL2 and CXCL12 (show CXCL12 Antibodies) and promote the migration of enhanced green fluorescent protein-positive bone marrow stromal cells to bone defect site.

  2. In a cerebral aneurysm, expression of MCP1 peaked after induction for one week, then decreased. MCP1 induced macrophage adhesion and infiltration in the artery wall of aneurysms, and contributed to the occurrence and development of brain aneurysm.

  3. Data show that the serum levels of mast cell tryptase, monocyte chemoattractant protein-1 (MCP-1) and interleukin-8 (IL-8 (show IL8 Antibodies)) decreased significantly in Dachengqi decoction treatment group.

  4. measurements of CCL2 and macrophages can serve as new inflammatory biomarkers to evaluate the safety of promising novel microbicides for prevention of HIV.

  5. Expression of MCP-1 was successfully inhibited by transfecting MCP-1 siRNA expression plasmid to the carotid artery, and the progression of atherosclerosis was restricted by RNAi-mediated silencing of MCP-1 expression.

Pig (Porcine) Chemokine (C-C Motif) Ligand 2 (CCL2) interaction partners

  1. CXCL10 (show CXCL10 Antibodies) protein was detected in serum from pigs infected with a high virulence African swine fever virus isolate. Levels of CCL2 mRNA were increased in pigs infected with the high virulence isolate compared to a low virulence isolate.

  2. Porcine CCL2 binding on Tuk4+SLA (show SLA Antibodies)-II- but not on Tuk4-SLA (show SLA Antibodies)-II+ cells was detected by using a CCL2-green fluorescence protein fusion protein.

  3. The protective properties of flavonoids, such as EGCG, against endothelial inflammation may be regulated in part though induction of HO-1 and subsequent activator protein-1 signaling.

  4. MCP-1 contributes to functional and structural impairment in the kidney in renal artery stenosis, mainly in the tubulointerstitial compartment

  5. Contrast media did not affect bone marrow cell viability/MCP-1 secretion.

  6. Porcine vessel wall injury via balloon arthroplasty upregulates expression of CCL2 by coronary artery transmural and perivascular cells in a sequential pattern.

  7. in the aortic arch expression of monocyte chemoattractant protein 1 (MCP-1) was upregulated, compared with the thoracic aorta

  8. Variable gene expression (eg, matrix metalloproteinase-9 (show MMP9 Antibodies), CCL2 and Lp-PLA(2 (show Lp-PLA2 Antibodies)) mRNAs), both in regard to the arterial bed and duration of disease, was associated with variable plaque development and progression.

  9. myocardial infarction induced proinflammatory gene and protein expression in peripheral blood mononuclear cells of tissue factor (show F3 Antibodies) cyclo-oxygenase-2, monocyte chemoattractant protein-1 and CRP (show CRP Antibodies)

Chemokine (C-C Motif) Ligand 2 (CCL2) Antigen Profile

Protein Summary

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.

Gene names and symbols associated with CCL2

  • chemokine (C-C motif) ligand 2 (CCL2) antibody
  • chemokine (C-C motif) ligand 2 (Ccl2) antibody
  • macrophage cationic peptide 1 (MCP-1) antibody
  • mast cell proteinase-1 (MCP1) antibody
  • AI323594 antibody
  • GDCF-2 antibody
  • HC11 antibody
  • HSMCR30 antibody
  • JE antibody
  • MCAF antibody
  • MCP-1 antibody
  • MCP-1A antibody
  • MCP1 antibody
  • MCP1A antibody
  • SCYA2 antibody
  • Sigje antibody
  • SMC-CF antibody

Protein level used designations for CCL2

small inducible cytokine A2 , C-C motif chemokine 2 , immediate-early serum-responsive JE protein , immediate-early serum-responsive protein JE , monocyte chemoattractant protein 1 , monocyte chemoattractant protein-1 , monocyte chemotactic protein 1 , small inducible gene JE , small-inducible cytokine A2 , monocyte chemotactic and activating factor , monocyte secretory protein JE , small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je) , small inducible cytokine subfamily A (Cys-Cys), member 2 , platelet-derived growth factor-inducible protein JE , acidic seminal fluid protein , monocyte chemotactic protein 1A , MCP-1 , chemokine CCL2/MCP-1 , CS-III , NP-1 , antiadrenocorticotropin peptide III , corticostatin III , corticostatin-3 , macrophage antibiotic peptide MCP-1 , SMCP-1A , mast cell protease 1A

748205 Pan troglodytes
24770 Rattus norvegicus
6347 Homo sapiens
20296 Mus musculus
281043 Bos taurus
100009130 Oryctolagus cuniculus
397422 Sus scrofa
403981 Canis lupus familiaris
100135494 Cavia porcellus
100034136 Equus caballus
100172740 Pongo abelii
101120093 Ovis aries
574138 Macaca mulatta
100009115 Oryctolagus cuniculus
443546 Ovis aries
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