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CCL2 antibody
CCL2
Reactivity: Human, Mouse, Monkey
WB, ELISA, IHC, IF/ICC, FACS
Host: Mouse
Monoclonal
unconjugated
Product Details anti-CCL2 Antibody
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Target
See all CCL2 Antibodies
CCL2
(Chemokine (C-C Motif) Ligand 2 (CCL2))
Reactivity
All reactivities for CCL2 antibodies
Human, Mouse, Monkey
Host
All hosts for CCL2 antibodies
Mouse
Clonality
All clonalities for CCL2 antibodies
Monoclonal
Conjugate
All conjugates for CCL2 antibodies
This CCL2 antibody is un-conjugated
Application
All applications for CCL2 antibodies
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (fixed cells) (IF/ICC), Flow Cytometry (FACS)
Purification
Purified antibody
Immunogen
Purified recombinant fragment of human CCL2 expressed in E. Coli.
Isotype
IgG1
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1.0 mg/mL
Buffer
PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Target Details for CCL2
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Target
CCL2
(Chemokine (C-C Motif) Ligand 2 (CCL2))
Alternative Name
CCL2 (CCL2 Products )
Synonyms
GDCF-2 antibody, HC11 antibody, HSMCR30 antibody, MCAF antibody, MCP-1 antibody, MCP1 antibody, SCYA2 antibody, SMC-CF antibody, AI323594 antibody, JE antibody, Scya2 antibody, Sigje antibody, MCP-1A antibody, MCP1A antibody, C-C motif chemokine ligand 2 antibody, chemokine (C-C motif) ligand 2 antibody, C-C motif chemokine 2 antibody, CCL2 antibody, Ccl2 antibody, LOC101120093 antibody
Background
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
Molecular Weight
11 kDa
Gene ID
6347
UniProt
P13500
Pathways
Cellular Response to Molecule of Bacterial Origin , Positive Regulation of Immune Effector Process , ER-Nucleus Signaling , Unfolded Protein Response , The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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