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anti-Chemokine (C-C Motif) Receptor 4 (CCR4) Antibodies

The protein encoded by CCR4 belongs to the G-protein-coupled receptor family . Additionally we are shipping CCR4 Kits (20) and CCR4 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CCR4 104625 Q8K3P5
CCR4 287249 Q6AXU9
CCR4 1233 P51679
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Top anti-CCR4 Antibodies at

Showing 10 out of 198 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CCR4 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 721_B cell lysate 100 μL Log in to see 2 to 3 Days
Human Goat Un-conjugated ICC, FACS, IHC (fro), IF, IHC (p), IHC, ELISA, WB Immunohistochemistry on paraffin section of human spleen 0.1 mg Log in to see 5 to 7 Days
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat exfoliated cells tissue labeled with Anti-CCR4 Polyclonal Antibody, Unconjugated (ABIN738666) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat cells labeled with Anti-CCR4/CD194 Polyclonal Antibody, Unconjugated (ABIN738666) followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
Cow Rabbit Un-conjugated EIA, IHC (fro), IP, WB   0.1 mg Log in to see 6 to 8 Days
Human Mouse Un-conjugated cELISA, FACS FACS analysis of BOSC23 cells using KH-4F5. BOSC23 cells were transientlytransfected with an expression vector encodingeither CCR4 (red curve) or an irrelevant protein(control transfectant). Binding of KH-4F5 was detected with a PE conjugated secondary antibody. A positive signal was obtained only with CCR4 transfected cells. Spectral Confocal Microscopy of CHO cells using KH-4F5. CHO cells were transiently transfected with an expression vector encoding CCR4. Binding of KH-4F5 was visualized with a FITC-conjugated secondary antibody (green). Actin filaments are labeled with A 100 μg Log in to see 5 to 6 Days
Human Rabbit Un-conjugated IHC (p) 50 μg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IHC (p), WB Anti-CCR4 antibody, Western blotting Lane 1: CEM Cell Lysate Lane 2: JURKAT Cell Lysate Lane 3: HELA Cell Lysate Anti-CCR4 antibody, IHC(P) IHC(P): Human Tonsil Tissue 100 μg Log in to see 4 to 6 Days
Mouse Rabbit Un-conjugated WB Anti-CCR4 antibody, Western blotting All lanes: Anti CCR4  at 0.5ug/ml Lane 1: Rat Thymus Tissue Lysate at 50ug Lane 2: Rat Spleen Tissue Lysate at 50ug Lane 3: HEPA Whole Cell Lysate at 40ug Predicted bind size: 41KD Observed bind size: 41KD 100 μg Log in to see 4 to 6 Days
Human Rabbit Un-conjugated IF, ELISA Immunofluorescence analysis of HuvEc cells, using CCR4 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated EIA, IHC (p) 50 μg Log in to see 6 to 8 Days

CCR4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CCR4 Antibodies

  1. Human Polyclonal CCR4 Primary Antibody for ICC, FACS - ABIN152140 : Power, Meyer, Nemeth, Bacon, Hoogewerf, Proudfoot, Wells: Molecular cloning and functional expression of a novel CC chemokine receptor cDNA from a human basophilic cell line. in The Journal of biological chemistry 1995 (PubMed)
    Show all 6 references for ABIN152140

  2. Human Monoclonal CCR4 Primary Antibody for cELISA, FACS - ABIN179723 : Andrew, Ruffing, Kim, Miao, Heath, Li, Murphy, Campbell, Butcher, Wu: C-C chemokine receptor 4 expression defines a major subset of circulating nonintestinal memory T cells of both Th1 and Th2 potential. in Journal of immunology (Baltimore, Md. : 1950) 2001 (PubMed)
    Show all 5 references for ABIN179723

  3. Cow (Bovine) Polyclonal CCR4 Primary Antibody for EIA, IHC (fro) - ABIN492852 : Tran, Miller: Chemokine receptors: signposts to brain development and disease. in Nature reviews. Neuroscience 2003 (PubMed)
    Show all 3 references for ABIN492852

  4. Human Polyclonal CCR4 Primary Antibody for IF (p), IHC (p) - ABIN738666 : Ge, Li, Jiang, You, Liu, Zhong, Huang, Xing: Integration of nondegradable polystyrene and degradable gelatin in a core-sheath nanofibrous patch for pelvic reconstruction. in International journal of nanomedicine 2015 (PubMed)

  5. Cow (Bovine) Polyclonal CCR4 Primary Antibody for WB - ABIN2792190 : Nakayama, Hieshima, Arao, Jin, Nagakubo, Shirakawa, Yamada, Fujii, Oiso, Kawada, Nishio, Yoshie: Aberrant expression of Fra-2 promotes CCR4 expression and cell proliferation in adult T-cell leukemia. in Oncogene 2008 (PubMed)

More Antibodies against CCR4 Interaction Partners

Mouse (Murine) Chemokine (C-C Motif) Receptor 4 (CCR4) interaction partners

  1. CCR4 is involved in immunosuppression after severe sepsis and suggest that CCR4+ Regulatory T Cells negatively modulate the short and long-term immune responses.

  2. CCL22 (show CCL22 Antibodies) was localised mainly on the cell surface and or in the cytoplasm. Within sections of omental milky spot micrometastases, CCR4 was recognised on or in gastric cancer cells, constituent cells milky spots, blood cells and blood endothelial cells

  3. CCR4 is involved in regulating negative selection of polyclonal and T cell receptor (TCR) transgenic thymocytes

  4. results show that the IL-4 (show IL4 Antibodies)/CCL22 (show CCL22 Antibodies)/CCR4 axis is involved in the migration of Tregs to osteolytic lesion sites, and attenuates development of lesions by inhibiting inflammatory migration and the production of proinflammatory and osteoclastogenic mediators

  5. These data have uncovered a novel role of core components of the Ccr4-Not complex as regulators of transition from partial to genuine induced pluripotent stem cells.

  6. that effective engagement of CCR4 by CCL17 (show CCL17 Antibodies) involves two distinct binding domains and interaction with both is required for signaling

  7. NF-kappaB (show NFKB1 Antibodies) signaling pathway was involved in the asthmatic change induced by CKLF1, among which CCR4 might play a crucial role

  8. CCR4-expressing Th2cells play a critical role in the pathogenesis of bronchial asthma by producing Th2 cytokines.

  9. CCR4 promotes natural killer cell priming/activation by mediating contacts with sentinel cells in the lung.

  10. Combining a panel of thymocyte maturation markers with cell surface analysis of CCR7 (show CCR7 Antibodies) and CCR4 identifies distinct stages in the development of multiple alphabetaT cell lineages in the adult thymus.

Human Chemokine (C-C Motif) Receptor 4 (CCR4) interaction partners

  1. CCL22 (show CCL22 Antibodies)-specific antibodies reveal that engagement of two distinct binding domains on CCL22 (show CCL22 Antibodies) is required for CCR4-mediated function.

  2. CCR4 mutation is an important determinant of the clinical course in ATLL cases, and that NS and FS mutations of CCR4 behave differently with respect to ATLL pathophysiology.

  3. Distinctive Treg associated CCR4-CCL22 (show CCL22 Antibodies) expression profile with altered frequency of Th17/Treg cell in the immunopathogenesis of Pemphigus Vulgaris (show DSG3 Antibodies).

  4. Data show that CCR4 was over-expressed in lymph node-negative human gastric cancer tissues and suggest its involvement in promoting tumor invasion probably, through up-regulation of MMP9 (show MMP9 Antibodies).

  5. CCR4 C1014T and CCL22 (show CCL22 Antibodies) C16A genetic variations were neither associated with the risk, nor with the progression of colorectal cancer in Iranian population

  6. Higher percentages of CCR4+ CD4 (show CD4 Antibodies) TEM (show CYLD Antibodies) cells in acute RSV infection were accompanied with higher percentages of CXCR3 (show CXCR3 Antibodies)+ CD8 (show CD8A Antibodies) TEM (show CYLD Antibodies) cells, whereas the development of long-lived memory CXCR3 (show CXCR3 Antibodies)+ CD4 (show CD4 Antibodies) and CD8 (show CD8A Antibodies) TCM cells seems to be compromised

  7. These findings implicate somatic gain-of-function CCR4 mutations in the pathogenesis of adult T cell leukemia/lymphoma.

  8. CCR4 has a role in tumor aggressive behavior in renal cell carcinoma (show MOK Antibodies)

  9. Data show that CCR4 exists in at least two distinct conformations, which are differentially activated by ligand.

  10. CCR4 mediates CCL17 (show CCL17 Antibodies) induced cell migration via increased total RhoA (show RHOA Antibodies) and active RhoA (show RHOA Antibodies) protein levels in colon cancer cells.

CCR4 Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.

Gene names and symbols associated with CCR4

  • chemokine (C-C motif) receptor 4 (CCR4) antibody
  • CCR4-NOT transcription complex, subunit 6 (Cnot6) antibody
  • chemokine (C-C motif) receptor 4 (Ccr4) antibody
  • A230103N10Rik antibody
  • AA407540 antibody
  • AW456442 antibody
  • C-C CKR-4 antibody
  • CC-CKR-4 antibody
  • CCR4 antibody
  • CD194 antibody
  • CHEMR1 antibody
  • ChemR13 antibody
  • CKR4 antibody
  • Cmkbr4 antibody
  • HGCN:14099 antibody
  • K5-5 antibody
  • LESTR antibody
  • RGD1310783 antibody
  • Sdf1r antibody

Protein level used designations for CCR4

chemokine (C-C motif) receptor 4 , C-C chemokine receptor type 4-like , c-C chemokine receptor type 4-like , CCR4-NOT transcription complex subunit 6 , carbon catabolite repressor protein 4 homolog , cytoplasmic deadenylase , C-C CKR-4 , C-C chemokine receptor type 4 , CCR-4 , chemokine (C-C) receptor 4 , CC chemokine receptor 4 , CC-CKR-4 , fusin , leukocyte-expressed seven-transmembrane-domain receptor , C-C chemokine receptor 4

100397096 Callithrix jacchus
100445664 Pongo abelii
100585668 Nomascus leucogenys
104625 Mus musculus
287249 Rattus norvegicus
1233 Homo sapiens
403541 Canis lupus familiaris
408019 Bos taurus
12773 Mus musculus
171054 Rattus norvegicus
Selected quality suppliers for anti-CCR4 (CCR4) Antibodies
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